#HostVirusInteractions
LightNews LightNews
evbc.bsky.social
VECOS enables direct CRISPR-based investigation of host–virus interactions by embedding sgRNA libraries in viral genomes, yielding precise, multidimensional data on viral propagation dynamics.
#VirusBioinformatics #HostVirusInteractions 🔬🧬
📄 doi.org/10.1038/s415...
👤 EVBC member: Noam Stern-Ginossar
Multidimensional analysis of host–virus interactions using the virus-encoded CRISPR-based direct readout system (VECOS) - Nature Protocols
In the virus-encoded CRISPR-based direct readout system, single-guide RNA libraries are expressed directly from the genomes of viruses so that single-guide RNA abundance at distinct stages of the vira...
doi.org
November 10, 2025 at 4:24 PM
evbc.bsky.social
🧬🔬 New #CRISPR-based approach VECOS enables direct, stage-specific readouts of gene perturbations during infection cycles via sgRNA libraries and maps #HostVirusInteractions with high resolution. #FunctionalGenomics
📄 https://doi.org/10.1038/s41596-025-01242-9
👤 EVBC member: Noam Stern-Ginossar
Multidimensional analysis of host–virus interactions using the virus-encoded CRISPR-based direct readout system (VECOS) - Nature Protocols
In the virus-encoded CRISPR-based direct readout system, single-guide RNA libraries are expressed directly from the genomes of viruses so that single-guide RNA abundance at distinct stages of the viral infection cycle provides direct and quantitative readout of gene-perturbation effects on viral propagation.
doi.org
May 4, 2026 at 7:29 AM