#IL-27p28
A paper using RRID:AB_466346 from @thermofishersci.bsky.social was just published in eLife. RRIDs improve reproducibility in scientific research. #ReproducibleResearch #OpenScience #accelerateopenscience
Thymic dendritic cell-derived IL-27p28 promotes the establishment of functional bias against IFN-γ production in newly generated CD4+ T cells through STAT1-related epigenetic mechanisms
doi.org
May 29, 2025 at 7:00 AM
Egypt, 242 COVID-19 patients, 187 controls: IL-27 gene variants linked to higher infection risk but not severity.

IFITM3 gene variant showed no clear effect.

virologyj.biomedcentral.com/articles/10....
Impact of single nucleotide polymorphism of IL-27P28 rs153109 and IFITM3 rs12252 on susceptibility and severity of COVID-19 in Egyptian patients: a case control study - Virology Journal
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes Coronavirus disease 2019 (COVID-19), which is a huge global health threat. Interleukin27 (IL-27) gene is a cytokine that ...
virologyj.biomedcentral.com
March 10, 2025 at 1:41 PM
Thymic dendritic cell-derived IL-27p28 promotes the establishment of functional bias against IFN-γ production in newly generated CD4+ T cells through STAT1-related epigenetic mechanisms https://www.biorxiv.org/content/10.1101/2024.03.02.583138v1
Thymic dendritic cell-derived IL-27p28 promotes the establishment of functional bias against IFN-γ production in newly generated CD4+ T cells through STAT1-related epigenetic mechanisms https://www.biorxiv.org/content/10.1101/2024.03.02.583138v1
The newly generated CD4 single-positive (SP) T lymphocytes are featured by enhanced IL-4 but repress
www.biorxiv.org
March 6, 2024 at 7:21 PM
Thymic dendritic cell-derived IL-27p28 promotes the establishment of functional bias against IFN-γ production in newly generated CD4+ T cells through STAT1-related epigenetic mechanisms https://www.biorxiv.org/content/10.1101/2024.03.02.583138v1
Thymic dendritic cell-derived IL-27p28 promotes the establishment of functional bias against IFN-γ production in newly generated CD4+ T cells through STAT1-related epigenetic mechanisms https://www.biorxiv.org/content/10.1101/2024.03.02.583138v1
The newly generated CD4 single-positive (SP) T lymphocytes are featured by enhanced IL-4 but repress
www.biorxiv.org
March 6, 2024 at 7:21 PM
Project is straight out of 1995, but that early casdo data is great bait..... casdo/avastin/tecentriq, and #CHRS plans casdo/avastin/loqtorzi going forward. Great for loqtorzi, but crap for casdo if and when? #IL-27 #IL-27p28
November 29, 2024 at 8:54 PM