#IL33
IL33 protects from recurrent C. difficile infection by restoration of humoral immunity
www.jci.org/articles/vie...
@jclinical-invest.bsky.social
March 7, 2025 at 8:02 PM
Agustus 🐕‍🦺
Adult male Border Collie mix
Adoptable from Henry County Humane Society - Geneseo (Geneseo, IL)

https://www.petfinder.com/dog/agustus-78846577/il/geneseo/henry-county-humane-society-geneseo-il33/
October 20, 2025 at 9:46 PM
#WeekendRead! #EveryOrganIsAnImmuneOrgan 😉! The Balachandran lab &co show @ Nature that the alarmin domain of IL33 expands lymphoneogenic ILC2s which favor tertiary lymphoid organ formation in colitis & during tumor growth! Engineered IL33 can be an antitumoral! www.nature.com/articles/s41...
IL-33-activated ILC2s induce tertiary lymphoid structures in pancreatic cancer - Nature
IL-33 induces tertiary lymphoid structures.
www.nature.com
January 19, 2025 at 3:52 PM
Our cool new paper depicting fibroblasts more than a scaffold during airway allergy. #Il33 #ILC2 #complement
December 3, 2025 at 1:34 AM
Aquaman 🐾
Baby female American Staffordshire Terrier mix
Adoptable from Henry County Humane Society - Geneseo (Geneseo, IL)

https://www.petfinder.com/dog/aquaman-78846733/il/geneseo/henry-county-humane-society-geneseo-il33/
October 21, 2025 at 1:45 AM
Step into a world of love and gentle purrs with, Seraphina, located in Geneseo, IL.

Learn more: https://www.petfinder.com/cat/seraphina-76535825/il/geneseo/henry-county-humane-society-geneseo-il33/
June 12, 2025 at 6:30 AM
Mini Me 🐕‍🦺
Adult female Cavalier King Charles Spaniel mix
Adoptable from Henry County Humane Society - Geneseo (Geneseo, IL)

https://www.petfinder.com/dog/mini-me-78846719/il/geneseo/henry-county-humane-society-geneseo-il33/
October 21, 2025 at 1:16 AM
Peritoneal cavity-derived GATA6+ macrophages inhibit fibrosis through IL33 in endometrium
doi.org/10.1101/2025...
Peritoneal cavity-derived GATA6+ macrophages inhibit fibrosis through IL33 in endometrium
Macrophages exhibit a high degree of plasticity and play pivotal roles both in the normal physiological cycle of the endometrium and in its regeneration following injury. Although some new subsets of ...
doi.org
February 9, 2025 at 9:44 PM
Frito 🐶
Young male Yellow Labrador Retriever mix
Adoptable from Henry County Humane Society - Geneseo (Geneseo, IL)

https://www.petfinder.com/dog/frito-78387431/il/geneseo/henry-county-humane-society-geneseo-il33/
September 23, 2025 at 2:01 AM
Your couch companion and adventure ally awaits: Crue, located in Geneseo, IL.

Learn more: https://www.petfinder.com/dog/crue-77506980/il/geneseo/henry-county-humane-society-geneseo-il33/
August 3, 2025 at 7:00 AM
Thrilled to share our work that has indeed *complemented* ongoing research in the lab!!!🙌
#complement #IL33 #fibroblast #ILC2 #airwayallergy
December 3, 2025 at 2:09 AM
#LocationLocationLocation! Wang Eisenstein Waizman @yaleschoolofmed.bsky.social &co show @ Science Immunology that physical, chemical, & radiation skin damage induces IL33 activating ILC2 & transferring to distal barrier tissues the capacity to induce antibodies causing #allergic responses!
Skin damage signals mediate allergic sensitization to spatially unlinked antigen
Skin injury releases damage-encoded systemic signals that can initiate immunity to novel antigens introduced at distal barrier sites.
www.science.org
April 4, 2025 at 8:06 PM
IL33 is linked to allergic asthma but is differentially regulated in mice & humans

doi.org/10.1172/jci....
@annesperling1.bsky.social & team employ an elegant genetic tool to identify a neg feedback loop for endothelial IL33 expression in response to allergen or exogenous IL33
May 12, 2026 at 11:01 AM
Find a place in your heart for Saige, located in Geneseo, IL.

Learn more: https://www.petfinder.com/cat/saige-66143969/il/geneseo/henry-county-humane-society-geneseo-il33/
February 14, 2025 at 7:00 AM
Systemic IL33 following skin damage can mediate sensitizwtion to a bystander antigen in the gut

www.science.org/doi/10.1126/...
Skin damage signals mediate allergic sensitization to spatially unlinked antigen
Skin injury releases damage-encoded systemic signals that can initiate immunity to novel antigens introduced at distal barrier sites.
www.science.org
April 14, 2025 at 12:11 PM
Our previous work suggested that epithelial Il33 is driven by beta-catenin activation, so we tested that in organoids and in vivo

And found Wnt-induced beta-catenin activation drastically elevated Il33 levels /4
December 1, 2024 at 11:12 PM
Ready to add a little purr to your life? Say hello to, Julius, located in Geneseo, IL.

Learn more: https://www.petfinder.com/cat/julius-45361345/il/geneseo/henry-county-humane-society-geneseo-il33/
December 16, 2024 at 5:30 AM
Cool new study from Iliev lab at Weill Cornell Medicine showing a #commensalfungi that dominates the mycobiome of wild mice driving #eosinophilia and #type2immunity through the ST2-IL33 axis, resulting in enhanced resistant to helminth infection 👇 www.nature.com/articles/s41...
Fungal symbiont transmitted by free-living mice promotes type 2 immunity - Nature
Kazachstania pintolopesii is a highly prevalent fungal symbiont that can trigger type 2 immunity and influence the composition of the gut mycobiome, as well as immune and disease phenotypes.
www.nature.com
December 1, 2024 at 1:53 AM
Wow! Two Phase 3 RCTs demonstrate that tozorakimab, an IL33 monoclonal antibody reduces moderate-to-severe COPD exacerbations by 29% to 34%. Kudos to all Oberon, Titania investigators and #ShanaTova to the #CureCOPD community!!!
www.nejm.org/doi/full/10....
Tozorakimab to Prevent COPD Exacerbations | NEJM
Many patients with chronic obstructive pulmonary disease (COPD) have exacerbations despite receiving standard-of-care inhaled maintenance therapy. Dysregulated interleukin-33 signaling is implicate...
www.nejm.org
September 14, 2026 at 11:16 AM
Very interesting talk on revving up macrophages responses using a treatment with IL33 in Glioblastoma models by Dr Donna Senger
#CCRC2025
November 2, 2025 at 6:50 PM
Who controls type-2 immunity?

Turns out fibroblasts do , via a C3–IL-33–ILC2 axis that shapes allergic inflammation in vivo. @atakkatan.bsky.social

Our new work highlighted by @cellreports.bsky.social

#Immunology #StromalBiology #Allergy #Asthma #ILC2 #IL33 #Complement
December 13, 2025 at 4:34 PM
🎉 Our latest paper is out in #FrontiersInImmunology! Our study shows that IL33 and IL12 drive a potent TCR-independent activation program in human MAIT cells, promoting IFNγ production, metabolic reprogramming and immunomodulatory functions that shape monocyte responses. 🔬🧬 doi.org/10.3389/fimm...
doi.org
July 10, 2026 at 7:12 AM