#ILC2022
@EASLnews When the airline cancels your incoming flight to #ILC2022 due to “staffing issues” and books you on a flight that leaves 2 days later. “We upgraded you” fortunately was able to get on an earlier flight that gets in on June 21 after 90 minutes on the phone
December 3, 2024 at 1:53 AM
@EASLnews Less than 2 days to the start of #ILC2022. Highlights for me will be all things Baveno and checkpoint inhibitor immune mediated hepatitis. Staples of modern hepatology practice. #LiverTwitter
December 3, 2024 at 1:53 AM
What's in store for you at ILC 2022? https://easl.eu/blog/ilc2022/
What's in store for you at ILC 2022?
The International Liver Congress™ is around the corner, a...
easl.eu
December 3, 2024 at 1:53 AM
@EASLnews 1st international flight in 2 yrs (Mexico and Canada excluded) and going as poorly as expected. Cancellations, delays and a @LondonTubeLive strike awaiting me at @HeathrowAirport . #ilc2022 + human, ZOOM-FREE interaction should make it well worth the inconvenience
December 3, 2024 at 1:53 AM
@EASLnews To quote Barry Manilow:
“looks like we made it”
Bonus view of the English countryside #ilc2022
December 3, 2024 at 1:53 AM
@EASLnews @ggarciatsao @YaleDigestive:
Decompensated advanced chronic liver disease (dACLD)=onset of ascites, varciceal bleed, HE. Jaundice currently “debated” but doesn’t define dACLD
Jaundice, second event, HRS and SBP is further decomp event=80% mortality at 5y #ILC2022
December 3, 2024 at 1:53 AM
@EASLnews Prof. Genesca @UGTValleHebron nice summary of LSM and how it ties into risk of liver related events #ILC2022
December 3, 2024 at 1:48 AM
@EASLnews LSM 20-25 and plt<150 = at least 60% likely to have CSPH (HVPG 7 mm Hg or more). Obese NASH throws this off to some extent because LSM for NASH sucks #ILC2022
December 3, 2024 at 1:48 AM
@EASLnews risk of liver related events much lower for #NAFLD than other etiologies #ILC2022
December 3, 2024 at 1:48 AM
@EASLnews prof Tsochatzis @ucl main issue with #NAFLD is that PPV of LSM for CSPH is not as good as for other etiologies. Not clear why and how BMI factors into it #ILC2022
December 3, 2024 at 1:48 AM
@EASLnews prof. Tsochatzis: it’s difficult to justify starting carvedilol for CSPH even with high LSM if a #NAFLD patient has CPT A5 because NNT to prevent decomp would be very high #ILC2022
December 3, 2024 at 1:48 AM
@EASLnews interesting point raised by @ggarciatsao during Q&A: if patient has simultaneous onset of 2 decomp events, this doesn’t seem to raise their mortality risk like it would if they developed one and then the other at a later time interval. #ILC2022
December 3, 2024 at 1:48 AM
@EASLnews @DJPinato @imperialcollege addresses the elusive task of predictive biomarkers to IO therapy in #HCC #ILC2022
December 3, 2024 at 1:48 AM
@DJPinato @EASLnews @EASLedu what might biomarkers of response to #Immunotherapy in #HCC look like? A general overview below #ILC2022
December 3, 2024 at 1:48 AM
@EASLedu @EASLnews great discussion of all things predictive biomarkers in #HCC @LorenzaRimassa @DJPinato @NaultJc #ILC2022
December 3, 2024 at 1:48 AM
@EASLedu @EASLedu Prof. Mario Rizetto, a fitting honorary president of #ILC2022 at the time when new and exciting things are happening in #HDV
December 3, 2024 at 1:18 AM
@EASLedu @EASLnews congratulations to @salvatore_piano for a well deserved Emerging leader award #ILC2022
December 3, 2024 at 1:13 AM
@docberza nice summary of NITs for assessment of liver fibrosis @EASLnews @EASLedu #ILC2022
December 3, 2024 at 1:13 AM
@EASLedu @EASLnews @docberza draws attention to important pitfalls to interpreting LSM #ILC2022
December 3, 2024 at 1:13 AM
@EASLedu @EASLnews so far this has been a #BIOMARKER meeting par excellence
✅ Predictors of dACLD
✅ NITs in #NAFLD
✅ response to IO rx in #HCCref="/hashtag/HCC" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link">#HCC
✅ severity of liver disease for organ allocation
✅ biomarkers for diagnosis and follow up of #HCC
#ILC2022
December 3, 2024 at 1:13 AM
@EASLnews @EASLedu @RautouE Liver surface nodularity on CT, multiparametric MRE, presence of Porto systemic shunts and hepatocyte extra cellular vesicles may also be promising quantifiable biomarkers #ILC2022
December 3, 2024 at 1:13 AM
@EASLedu @EASLnews @elizabeth_verna shows the decline in the performance of #MELD and MELD-Na in predicting wait list mortality. Possible drivers: tx for alcohol related hepatitis and rise in number of people with CKD related to metabolic risk #ILC2022
December 3, 2024 at 1:13 AM
@EASLedu @EASLnews @elizabeth_verna highlights sex disparities in MELD performance related to body size and more importantly the fact that creatinine overestimates eGFR in women compared to men #ILC2022
December 3, 2024 at 1:13 AM
@EASLedu @elizabeth_verna eGFR estimate equations instead of creatinine may help address disparities. Equations that include sex and cystatin c may be better.
Edit. Note: not a big fan of cystatin C
#ILC2022
December 3, 2024 at 1:13 AM
⁦@EASLedu⁩ @EASLnews⁩ link to MELD 3.0 below. This is currently under consideration for replacement of previous version as early as next weekand may address issues with albumin, CKD and sex disparities #ilc2022 https://medcalculators.stanford.edu/meld
medcalculators | MELD 3.0
medcalculators.stanford.edu
December 3, 2024 at 1:13 AM