Sounds promising! Glad to see RFK hasn’t deleted this study from PubMed yet pubmed.ncbi.nlm.nih.gov/41363805/
Universal Base-Edited CAR7 T Cells for T-Cell Acute Lymphoblastic Leukemia - PubMed
Universal BE-CAR7 T cells induced leukemic remission in patients with relapsed or refractory T-cell ALL, thus allowing successful allogeneic hematopoietic stem-cell transplantation in most of the patients. (Funded by the Medical Research Council and others; ISRCTN Registry number, ISRCTN15323014.).
pubmed.ncbi.nlm.nih.gov
January 31, 2026 at 4:29 PM
Sounds promising! Glad to see RFK hasn’t deleted this study from PubMed yet pubmed.ncbi.nlm.nih.gov/41363805/
"A clinical trial to determine the safety and immune responses to a new vaccine against Hantavirus disease"
https://www.isrctn.com/ISRCTN17868912
https://www.isrctn.com/ISRCTN17868912
ISRCTN
www.isrctn.com
May 12, 2026 at 7:51 AM
"A clinical trial to determine the safety and immune responses to a new vaccine against Hantavirus disease"
https://www.isrctn.com/ISRCTN17868912
https://www.isrctn.com/ISRCTN17868912
This is interesting
⬇️
"A clinical trial to determine the safety and immune responses to a new vaccine against Hantavirus disease" ( @apsmunro.bsky.social )
https://www.isrctn.com/ISRCTN17868912
⬇️
"A clinical trial to determine the safety and immune responses to a new vaccine against Hantavirus disease" ( @apsmunro.bsky.social )
https://www.isrctn.com/ISRCTN17868912
ISRCTN
www.isrctn.com
May 6, 2026 at 8:00 AM
This is interesting
⬇️
"A clinical trial to determine the safety and immune responses to a new vaccine against Hantavirus disease" ( @apsmunro.bsky.social )
https://www.isrctn.com/ISRCTN17868912
⬇️
"A clinical trial to determine the safety and immune responses to a new vaccine against Hantavirus disease" ( @apsmunro.bsky.social )
https://www.isrctn.com/ISRCTN17868912
December 1st marks #WorldAIDSDay 2025. Across our Research Communities, we are sharing a selection of blogs from researchers around the world that explore the latest insights on HIV and AIDS.
➡️ Find out more here: spklr.io/63323BVkSv
#WorldAIDSDay2025 #EndAIDS
➡️ Find out more here: spklr.io/63323BVkSv
#WorldAIDSDay2025 #EndAIDS
World AIDS Day 2025
In this blog, we share a selection of Springer Nature journal articles, collections, ISRCTN clinical studies, books, and blogs to celebrate World AIDS Day 2025.
spklr.io
December 1, 2025 at 2:14 PM
December 1st marks #WorldAIDSDay 2025. Across our Research Communities, we are sharing a selection of blogs from researchers around the world that explore the latest insights on HIV and AIDS.
➡️ Find out more here: spklr.io/63323BVkSv
#WorldAIDSDay2025 #EndAIDS
➡️ Find out more here: spklr.io/63323BVkSv
#WorldAIDSDay2025 #EndAIDS
This blog commemorates #RareDiseaseDay2025 by sharing a selection of @springernature.com journal articles, collections, ISRCTN clinical study registrations and blog posts chosen by our publishers.
go.nature.com/3EIatgF
go.nature.com/3EIatgF
Rare Disease Day 2025 - “Raising awareness and generating change for the 300 million people worldwide living with a rare disease, their families and carers.”
This blog commemorates Rare Disease Day by sharing a selection of Springer Nature journal articles, collections, ISRCTN clinical study registrations and blog posts chosen by our publishers.
go.nature.com
February 19, 2025 at 10:46 AM
This blog commemorates #RareDiseaseDay2025 by sharing a selection of @springernature.com journal articles, collections, ISRCTN clinical study registrations and blog posts chosen by our publishers.
go.nature.com/3EIatgF
go.nature.com/3EIatgF
2) The repeated statements on physical and mental health rehabilitation (that it improves depression, quality of life, and recovery) are all based on 1 study: the REGAIN trial.
pubmed.ncbi.nlm.nih.gov/38325873/
pubmed.ncbi.nlm.nih.gov/38325873/
Clinical effectiveness of an online supervised group physical and mental health rehabilitation programme for adults with post-covid-19 condition (REGAIN study): multicentre randomised controlled trial...
ISRCTN registry ISRCTN11466448.
pubmed.ncbi.nlm.nih.gov
November 29, 2024 at 3:35 PM
2) The repeated statements on physical and mental health rehabilitation (that it improves depression, quality of life, and recovery) are all based on 1 study: the REGAIN trial.
pubmed.ncbi.nlm.nih.gov/38325873/
pubmed.ncbi.nlm.nih.gov/38325873/
April marks 25 years since the first records published on ISRCTN, the UK's Clinical Study Registry! On thia occasion, we've compiled some Q&A blogs with the researchers behind some of our milestone records, and some infographics showing how far trial registration has come in that time.
#MedSky
#MedSky
25 years of ISRCTN registry: a timeline
The ISRCTN registry is the UK's clinical study registry recognised by the World Health Organisation (WHO). To celebrate 25 years since the publication of the first study records in April 2000, in this timeline we look back at the history of ISRCTN and the key milestones in its development.
bit.ly
April 19, 2025 at 3:30 PM
April marks 25 years since the first records published on ISRCTN, the UK's Clinical Study Registry! On thia occasion, we've compiled some Q&A blogs with the researchers behind some of our milestone records, and some infographics showing how far trial registration has come in that time.
#MedSky
#MedSky
In this post we take a look at a selection of the ongoing clinical studies of possible new vaccines and treatments for Bundibugyo virus disease registered with WHO-recognised registries including ISRCTN, the UK’s clinical study registry: spklr.io/63320ER7w0
#PublicHealth 🩺
#PublicHealth 🩺
The Ebola Bundibugyo virus outbreak: clinical studies in progress
Taking a look at a selection of the ongoing clinical studies of possible new vaccines and treatments for Bundibugyo virus disease registered with WHO-recognised registries including ISRCTN, the UK’s clinical study registry.
spklr.io
August 24, 2026 at 12:52 PM
In this post we take a look at a selection of the ongoing clinical studies of possible new vaccines and treatments for Bundibugyo virus disease registered with WHO-recognised registries including ISRCTN, the UK’s clinical study registry: spklr.io/63320ER7w0
#PublicHealth 🩺
#PublicHealth 🩺
Registered: "Understanding the changing needs of autistic children in speech and language therapy services: exploring children’s priorities and preferences alongside current practice" www.isrctn.com/ISRCTN11768137 3-phase study including autistics aged 9-17 & SLTs (speech and language therapists)
ISRCTN
www.isrctn.com
March 23, 2026 at 8:52 AM
Registered: "Understanding the changing needs of autistic children in speech and language therapy services: exploring children’s priorities and preferences alongside current practice" www.isrctn.com/ISRCTN11768137 3-phase study including autistics aged 9-17 & SLTs (speech and language therapists)
Registered: "Is the Strengths and Needs Assessment acceptable for use by autistic adults after receiving an autism diagnosis? What are the potential benefits or harms of completing the Strengths and Needs Assessment?" www.isrctn.com/ISRCTN10283350 N=72 acceptability & feasibility RCT
ISRCTN
www.isrctn.com
February 12, 2025 at 10:13 AM
Registered: "Is the Strengths and Needs Assessment acceptable for use by autistic adults after receiving an autism diagnosis? What are the potential benefits or harms of completing the Strengths and Needs Assessment?" www.isrctn.com/ISRCTN10283350 N=72 acceptability & feasibility RCT
At the University of Manchester and Salford Royal NHS, 100 patients with long COVID joined a trial of a self-help lymphatic drainage routine.
Fatigue dropped more in the treatment group than in controls after 3 months, suggesting early promise.
pubmed.ncbi.nlm.nih.gov/41442105/
Fatigue dropped more in the treatment group than in controls after 3 months, suggesting early promise.
pubmed.ncbi.nlm.nih.gov/41442105/
Testing the Feasibility of a Self-Help Intervention That Includes Lymphatic Drainage to Reduce Fatigue-Related Symptoms Among Patients with Long COVID in General Practice: Experiences from Our Randomized Controlled Trial (RCT) - PubMed
International Standard Randomized Controlled Trial Number (ISRCTN): 99840264.
pubmed.ncbi.nlm.nih.gov
December 24, 2025 at 8:15 PM
At the University of Manchester and Salford Royal NHS, 100 patients with long COVID joined a trial of a self-help lymphatic drainage routine.
Fatigue dropped more in the treatment group than in controls after 3 months, suggesting early promise.
pubmed.ncbi.nlm.nih.gov/41442105/
Fatigue dropped more in the treatment group than in controls after 3 months, suggesting early promise.
pubmed.ncbi.nlm.nih.gov/41442105/
Registered: "This is a feasibility study of psychological well-being groups for autistic teenagers, called an autism social identity group (a-island)" which is "facilitated by two adults, one of whom will be autistic" www.isrctn.com/ISRCTN18332093 planned N=70 RCT (a-island vs care as usual)
ISRCTN
www.isrctn.com
December 15, 2025 at 9:47 AM
Registered: "This is a feasibility study of psychological well-being groups for autistic teenagers, called an autism social identity group (a-island)" which is "facilitated by two adults, one of whom will be autistic" www.isrctn.com/ISRCTN18332093 planned N=70 RCT (a-island vs care as usual)
Clinical trials analyses? Retrieve now also historic versions of #studies in CTGOV2 as structured data with #R #package ctrdata, supporting EUCTR (43,800 #trials), CTIS (780), CTGOV (490,000 studies) and ISRCTN (24,800) — feedback welcome paediatricdata.eu/cl...
Clinical trials analyses: ctrdata, a tool for leveraging register data – PaediatricData.EU
PaediatricData.EU informs policies and strategies for promoting child health, medical research and treatment development through analysis and discussion of public data sets
paediatricdata.eu
May 14, 2024 at 1:01 PM
Clinical trials analyses? Retrieve now also historic versions of #studies in CTGOV2 as structured data with #R #package ctrdata, supporting EUCTR (43,800 #trials), CTIS (780), CTGOV (490,000 studies) and ISRCTN (24,800) — feedback welcome paediatricdata.eu/cl...
The global community comes together for #WorldTBday on the 24th March every year. This blog commemorates the day by sharing a selection of articles, collections, ISRCTN clinical study registrations and blog posts chosen by our publishers.
World Tuberculosis Day 2025: Yes! We Can End TB : Commit, Invest, Deliver
For World Tuberculosis Day 2025, Springer Nature highlights contributions from our publishers and community that support this year's theme 'Yes! We Can End TB : Commit, Invest, Deliver’
spklr.io
March 24, 2025 at 2:58 PM
The global community comes together for #WorldTBday on the 24th March every year. This blog commemorates the day by sharing a selection of articles, collections, ISRCTN clinical study registrations and blog posts chosen by our publishers.
Microbiome research plays a vital role in understanding health and disease. On account of the recently observed World Microbiome Day, join us in celebrating the communities of microorganisms that live in and around us!
#MicrobiomeSky #MedSky
#MicrobiomeSky #MedSky
World Microbiome Day 2026
This blog commemorates World Microbiome Day in the context of SDG 3, by sharing a selection of Springer Nature journal articles, collections, ISRCTN clinical study registrations and blog posts on the Microbiome and its impact on SDG 3: Good health and well-being.
bit.ly
July 3, 2026 at 6:00 PM
Microbiome research plays a vital role in understanding health and disease. On account of the recently observed World Microbiome Day, join us in celebrating the communities of microorganisms that live in and around us!
#MicrobiomeSky #MedSky
#MicrobiomeSky #MedSky
Check out the protocol for the RELATE-YP study with @penninecarenhs.bsky.social authors #selfharm #youngpeople #cognitiveanalytictherapy @simonkaye.bsky.social @laurajeffreys.bsky.social @drsarahparry.bsky.social
pubmed.ncbi.nlm.nih.gov/42449446/
pubmed.ncbi.nlm.nih.gov/42449446/
Cognitive analytic therapy for self-harm with young people: protocol for the RELATE-YP feasibility randomized controlled trial - PubMed
The trial was pre-registered (01/08/25) on ISR CTN (ISRCTN code: ISRCTN11505839).
pubmed.ncbi.nlm.nih.gov
July 16, 2026 at 9:21 AM
Check out the protocol for the RELATE-YP study with @penninecarenhs.bsky.social authors #selfharm #youngpeople #cognitiveanalytictherapy @simonkaye.bsky.social @laurajeffreys.bsky.social @drsarahparry.bsky.social
pubmed.ncbi.nlm.nih.gov/42449446/
pubmed.ncbi.nlm.nih.gov/42449446/
How are children in Australia who've experienced grief being supported by a clinical study at Curtin University? Read the ISRCTN Registry's Q&A with Professor Sarah Egan, a clinical psychologist based within Curtin University in Perth, Australia, to find out more.
#MedSky #PsychSciSky
#MedSky #PsychSciSky
Supporting Kids in Loss - a Q&A with Professor Sarah Egan
This Q&A forms part of the upcoming SDG 3 Newsletter on Children and Young People, and focuses on the research of Professor Sarah Egan as part of the Project SKIL study on online Cognitive Behavioural Therapy.
bit.ly
May 1, 2025 at 4:30 PM
How are children in Australia who've experienced grief being supported by a clinical study at Curtin University? Read the ISRCTN Registry's Q&A with Professor Sarah Egan, a clinical psychologist based within Curtin University in Perth, Australia, to find out more.
#MedSky #PsychSciSky
#MedSky #PsychSciSky
New Article pubmed.ncbi.nlm.nih.gov/39806665/
Novel prehospital lactate cut-off estimation for mortality: a multicentre observational study - PubMed
ISRCTN Registry (ISRCTN17676798, ISRCTN48326533, ISRCTN49321933).
pubmed.ncbi.nlm.nih.gov
January 15, 2025 at 10:20 PM
New Article pubmed.ncbi.nlm.nih.gov/39806665/
February 4th marks #WorldCancerDay. Across our Research Communities, we are spotlighting journal articles, collections, clinical trial registrations and blogs that share the latest insights in cancer research.
#MedSky #OncoSky
#MedSky #OncoSky
World Cancer Day 2026: United by Unique
In this blog, we share a selection of Springer Nature journal articles, collections, ISRCTN clinical studies, books, and blogs to commemorate World Cancer Day 2026.
bit.ly
February 4, 2026 at 10:00 PM
February 4th marks #WorldCancerDay. Across our Research Communities, we are spotlighting journal articles, collections, clinical trial registrations and blogs that share the latest insights in cancer research.
#MedSky #OncoSky
#MedSky #OncoSky
Totton et al published an interesting review exploring what sample sizes have been used in pilot and feasibility studies over recent years 4/6
pilotfeasibilitystudies.biomedcentral.com/articles/10....
pilotfeasibilitystudies.biomedcentral.com/articles/10....
A review of sample sizes for UK pilot and feasibility studies on the ISRCTN registry from 2013 to 2020 - Pilot and Feasibility Studies
Background Pilot and feasibility studies provide information to be used when planning a full trial. A sufficient sample size within the pilot/feasibility study is required so this information can be e...
pilotfeasibilitystudies.biomedcentral.com
September 8, 2025 at 6:42 AM
Totton et al published an interesting review exploring what sample sizes have been used in pilot and feasibility studies over recent years 4/6
pilotfeasibilitystudies.biomedcentral.com/articles/10....
pilotfeasibilitystudies.biomedcentral.com/articles/10....
It is irrational to assert things without evidence.
It does, in fact, work. People are demonstrably, provably happier in spaces that have been designed and arranged according to the rules of Feng Shui. The practices it encourages mostly align with modern understandings of design.
It does, in fact, work. People are demonstrably, provably happier in spaces that have been designed and arranged according to the rules of Feng Shui. The practices it encourages mostly align with modern understandings of design.
A randomized controlled trial of Golden Ratio, Feng Shui, and evidence based design in healthcare - PubMed
The trial is registered with ISRCTN, ISRCTN10480033.
pubmed.ncbi.nlm.nih.gov
August 30, 2026 at 2:11 AM
It is irrational to assert things without evidence.
It does, in fact, work. People are demonstrably, provably happier in spaces that have been designed and arranged according to the rules of Feng Shui. The practices it encourages mostly align with modern understandings of design.
It does, in fact, work. People are demonstrably, provably happier in spaces that have been designed and arranged according to the rules of Feng Shui. The practices it encourages mostly align with modern understandings of design.
Did you know that last week marked 25 years since the first records were published on ISRCTN, a primary clinical trial registry?
Check out the series of blogs from milestones to infographics showing how far they’ve come: http://spklr.io/63327Aa7S
🩺 #medsky
Check out the series of blogs from milestones to infographics showing how far they’ve come: http://spklr.io/63327Aa7S
🩺 #medsky
April 17, 2025 at 4:42 PM
Did you know that last week marked 25 years since the first records were published on ISRCTN, a primary clinical trial registry?
Check out the series of blogs from milestones to infographics showing how far they’ve come: http://spklr.io/63327Aa7S
🩺 #medsky
Check out the series of blogs from milestones to infographics showing how far they’ve come: http://spklr.io/63327Aa7S
🩺 #medsky
Does anyone know where we could register a study that's *about* clinical trials but isn't a trial itself? ISRCTN etc. not suitable as it's focused on researcher education, not patient outcomes.
October 24, 2025 at 10:13 AM
Does anyone know where we could register a study that's *about* clinical trials but isn't a trial itself? ISRCTN etc. not suitable as it's focused on researcher education, not patient outcomes.