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zbw.weather.im
Urgent pilot report at 1800Z: ISP UUA /OV ISPT/TM 1800/FL014/TP A320/RM +10 KTS AND LIGHT TURB RWY 06 FINAL
September 25, 2026 at 6:02 PM
natmachinery.bsky.social
The Uracil-DNA Glycosylase2 UNG2 is degraded via a novel N-degron | CTLH-MKLN1-FAM72A E3 ligase recognizes the N-terminally acetylated UNG2 | @ispt-proteinterm.bsky.social
www.biorxiv.org/content/10.6...
September 22, 2026 at 11:41 AM
natmachinery.bsky.social
Coenzyme A biosynthesis is regulated by two distinct Ubiquitin E3 ligase complexes | UBR4-KCMF1 and MKLN1-CTLH independently converge on a common N-terminal MK Arg/N-degron to promote PANK degradation and restrict CoA biosynthesis | @ispt-proteinterm.bsky.social www.biorxiv.org/content/10.6...
Parallel Arg/N-degron recognition systems regulate coenzyme A biosynthesis
Coenzyme A (CoA) is an essential metabolic cofactor whose biosynthesis is controlled by pantothenate kinases (PANKs), the rate-limiting enzymes in CoA synthesis. Although CoA production is extensively...
www.biorxiv.org
September 21, 2026 at 7:44 AM
zbw.weather.im
Urgent pilot report at 1552Z: ISP UUA /OV ISPT/TM 1552/FLDURD/TP B738/SK BASES 015 BKN/RM RWY 15R
September 20, 2026 at 3:58 PM
natmachinery.bsky.social
Tideglusib as a First-in-Class Chemical Probe for the major N-terminal acetyltransferase NatA | By Rong Huang's lab and collaborators @ispt-proteinterm.bsky.social pubs.acs.org/acbcct/artic...
September 13, 2026 at 6:46 AM
linuxmanr4.bsky.social
⏱ Recordando artículos publicados #linuxmanr4
Función para calcular el ISPT 2014 en Excel y LibreOffice
August 21, 2026 at 3:53 PM
natmachinery.bsky.social
Symbiosis: An N-terminally acetylated peptide from the bacterium Photorhabdus modulates nematode development | Novel prokaryotic NAT enzyme PasC | @ispt-proteinterm.bsky.social www.pnas.org/doi/10.1073/...
An N-acetylated daropeptide modulates nematode development | PNAS
The symbiotic bacterium Photorhabdus is a rich source of bioactive secondary metabolites that mediate tripartite interactions with nematodes and in...
www.pnas.org
August 12, 2026 at 9:03 AM
natmachinery.bsky.social
α-Synuclein N-terminal acetylation tunes both its structural and physicochemical properties to enhance binding to lipid bilayers @ispt-proteinterm.bsky.social
pubs.acs.org/bichaw/artic...
N-Terminal Amine Chemistry Influences α-Synuclein Interactions with Lipid Bilayers
Abstract. α-Synuclein (αSyn) is an intrinsically disordered protein whose reversible membrane binding via amphipathic α-helix formation is central to its f
pubs.acs.org
July 28, 2026 at 2:33 PM
hpunkopunkt.bsky.social
das ist der "preis" für's nächste exklusiv-interview, sonst bekommt es eben jemand anders

aber ja, es ispt ein unding
July 1, 2026 at 7:05 AM
footyprime.bsky.social
Give it to me straight, Footy Prime!

We Do!

Let the Unpacking Begin+Rd. of 32 Beckons!
#CANMNT #CanadaSoccer #LACity
#FIFAWorldCup

GET IN!
Youtu.be/ISpt-cKuIqk💻

Full Paudio:
podcasts.apple.com/ca/podcast/foo…���
https://tu.be/ISpt-cKuIqk💻
June 25, 2026 at 3:41 PM
twegalcz.bsky.social
Ponkia slibuje virtuální realitu bez headsetu, stačí strčit hlavu do obří koule. Čínský startup Ponkia nabízí místo klasických VR brýlí 80centimetrovou kouli se 4K displejem uvnitř.

Zdroj: Ponkia / Indiegogo

Článek: www.twegal.com/novinky/ponk...

#ponkia #vr #gadgets #tech #hardware #future
Vizualizace terminálu Ponkia iSPT znázorňuje jeho využití při hraní videoher a simulátorů.
June 23, 2026 at 11:32 AM
natmachinery.bsky.social
Structural and mechanistic insights into the UBR4-KCMF1-Calmodulin complex @ispt-proteinterm.bsky.social academic.oup.com/proteincell/...
Structural and mechanistic insights into the UBR4-KCMF1-Calmodulin complex
Dear Editor,
academic.oup.com
June 23, 2026 at 9:20 AM
natmachinery.bsky.social
Structure of the E3 ligase CRL2ZYG11B with substrates reveals the molecular basis for N-degron recognition and ubiquitination. @ispt-proteinterm.bsky.social @cp-cellreports.bsky.social www.cell.com/cell-reports...
Structure of the E3 ligase CRL2ZYG11B with substrates reveals the molecular basis for N-degron recognition and ubiquitination
Liu et al. define how the CRL2ZYG11B ubiquitin ligase assembles and recognizes Gly/N-degron substrates by cryo-EM. Structures with an NLRP1 Gly/N-degron and SARS-CoV-2 ORF10 reveal extended substrate-...
www.cell.com
June 8, 2026 at 7:14 PM
leparisien.fr
Yvelines : des diagnostics médicaux effectués directement en prison grâce à une technologie… venue de l’espace
➡️ https://l.leparisien.fr/ispT
June 4, 2026 at 7:10 AM
natmachinery.bsky.social
New review out on protein N-terminal formylation - a stress-inducible modification of eukaryotic proteins #N-degron @ispt-proteinterm.bsky.social
www.nature.com/articles/s12...
N-terminal formylmethionine as a degron and a specific signal in proteostasis and stress adaptation - Experimental & Molecular Medicine
N-terminal methionine formylation, a protein modification once thought to be exclusive to bacteria and organelles, also occurs on proteins synthesized in the cytosol of yeast and human cells, challeng...
www.nature.com
May 8, 2026 at 1:03 PM
zbw.weather.im
Urgent pilot report at 1926Z: ISP UUA /OV ISPT/TM 1926/FLDURD/TP B738M/RM RWY24 +/- 10 KTS
April 22, 2026 at 7:28 PM
natmachinery.bsky.social
N-terminal cysteine dependent proteolysis of RGS4/5 is not sensitive to physiological oxidative stress | Preprint by Ya-Min Tian, Haeun Kim, Peter Ratcliffe & Thomas Keeley @ox.ac.uk @ispt-proteinterm.bsky.social #N-degron #cysteine www.biorxiv.org/content/10.6...
www.biorxiv.org
April 22, 2026 at 5:13 PM
zbw.weather.im
Urgent pilot report at 1427Z: ISP UUA /OV ISPT/TM 1427/FLDURD/TP BCS3/TB LGT/RM RWY 24 +10/-5 KTS
March 17, 2026 at 2:28 PM
zbw.weather.im
Urgent pilot report at 1400Z: ISP UUA /OV ISPT/TM 1400/FLDURD/TP E35L/TB LGT/RM RWY 24 +/- 10 KTS
March 17, 2026 at 2:01 PM
zbw.weather.im
Urgent pilot report at 2228Z: ISP UUA /OV ISPT/TM 2228/FLDURD/TP B737/SK BASES 003 BKN/RM RWY 24 BA GOOD
March 12, 2026 at 10:30 PM
zbw.weather.im
Urgent pilot report at 2317Z: ISP UUA /OV ISPT/TM 2317/FLDURD/TP C402/RM RWY 24 +/- 10 KTS, PRETTY CHOPPY
March 11, 2026 at 11:20 PM
zbw.weather.im
Urgent pilot report at 2238Z: ISP UUA /OV ISPT/TM 2238/FLDURD/TP BCS3/RM RWY 24 +/- 10 KTS
March 11, 2026 at 10:39 PM
zbw.weather.im
Urgent pilot report at 1625Z: ISP UUA /OV ISPT/TM 1625/FLDURD/TP B737/SK BASES OVC 002/RM RWY 06 BA GOOD
March 7, 2026 at 4:28 PM
zbw.weather.im
Urgent pilot report at 1711Z: ISP UUA /OV ISPT/TM 1711/FLDURD/TP A320/SK BASES OVC 007/RM RWY 06
March 6, 2026 at 5:13 PM
zbw.weather.im
Urgent pilot report at 1449Z: ISP UUA /OV ISPT/TM 1449/FLDURD/TP A320/SK BASES OVC 008/RM RWY 06
March 6, 2026 at 2:52 PM