#JAK1-#STAT6
Young Jun Kang shows that mitochondrial phosphatase #PGAM5 negatively regulates #IL4-induced anti-inflammatory responses and metabolic reprogramming of #Macrophages by controlling #JAK1-#STAT6 signaling
Mitochondrial phosphatase PGAM5 negatively regulates the induction of anti-inflammatory macrophages
Mitochondrial phosphatase PGAM5 negatively regulates IL-4-induced anti-inflammatory responses and metabolic reprogramming of macrophages by controlling JAK
doi.org
September 30, 2026 at 4:07 PM
The authors included RRIDs in their paper! Thanks for making your methods matter! #accelerateopenscience #reproducibility #ReproducibleResearch
Berberine suppresses hepatocellular carcinoma progression by blocking IL-4-JAK1-STAT6-mediated M2 polarization of macrophage
doi.org
February 1, 2026 at 8:03 AM
STAT5 and STAT3 balance shapes dendritic cell function and tumour immunity

Antibodies, plasmids and reagents Western blot analyses were performed using primary antibodies at a dilution of 1:1,000 unless otherwise specified. Anti-STAT1 (D1K9Y, 14994), anti-STAT2 (D9J7L, 72604), anti-STAT3 (Rabbit,…
STAT5 and STAT3 balance shapes dendritic cell function and tumour immunity
Antibodies, plasmids and reagents Western blot analyses were performed using primary antibodies at a dilution of 1:1,000 unless otherwise specified. Anti-STAT1 (D1K9Y, 14994), anti-STAT2 (D9J7L, 72604), anti-STAT3 (Rabbit, 79D7, 4904; Mouse, 124H6, 9139), anti-STAT4 (C46B10, 2653), anti-STAT5 (D2O6Y, 94205), anti-STAT6 (D3H4, 5397), anti-JAK1 (6G4, 3344), anti-JAK2 (D2E12, 3230), anti-JAK3 (D7B12, 8863), anti-TYK2 (E9H4T, 35615), anti-p65 (D14E12, 8242), anti-CD80 (E6J6N, 54521), anti-CD86 (E5W6H, 19589), anti-IL-6Rα (E7H4J, 39837), anti-GP130 (3732), anti-pSTAT1 (58D6, 9167), anti-pSTAT3 (D3A7, 9145), anti-pSTAT5 (D47E7, 4322), anti-pSTAT6 (D8S9Y, 56554), anti-pJAK1 (D7N4Z, 74129), anti-pJAK2 (C80C3, 3776), anti-pJAK3 (D44E3, 5031), anti-pp65 (93H1, 3033) and anti-β-actin (4967) were from Cell Signaling Technology.
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May 15, 2025 at 10:45 AM