Yes! It's even in my profile background
bsky.app/profile/jkpr...
bsky.app/profile/jkpr...
January 24, 2025 at 6:18 PM
Yes! It's even in my profile background
bsky.app/profile/jkpr...
bsky.app/profile/jkpr...
It's bittersweet leaving @jkpritch.bsky.social's group after 6 wonderful years. I had an amazing time in his lab, and cannot recommend this opportunity enough:
bsky.app/profile/jkpr...
bsky.app/profile/jkpr...
I have an opportunity to hire a staff scientist for my lab. Looking for someone with outstanding skillset in ML/statistics, genomics applications; interest in mentoring, strong publication record, PD experience required.
Email CV to me+cc my assistant (see 'contact' on my website). Ad to follow.
Email CV to me+cc my assistant (see 'contact' on my website). Ad to follow.
June 2, 2025 at 5:45 PM
It's bittersweet leaving @jkpritch.bsky.social's group after 6 wonderful years. I had an amazing time in his lab, and cannot recommend this opportunity enough:
bsky.app/profile/jkpr...
bsky.app/profile/jkpr...
I posted a couple days ago about our new paper on building causal graphs from genetic associations + Perturb-seq.
Here I want to expand on the value of using DIRECTIONAL information contained in LoF burden tests.🧵
[work led by @minetoota.bsky.social ]
bsky.app/profile/jkpr...
Here I want to expand on the value of using DIRECTIONAL information contained in LoF burden tests.🧵
[work led by @minetoota.bsky.social ]
bsky.app/profile/jkpr...
GWAS provides a unique tool in human biology as it can establish causal links from variants to trait.
But interpretation is difficult as most effects flow through (unobserved) gene regulatory networks. Can we gain insight by linking to modern Perturb-seq data?
www.biorxiv.org/content/10.1...
But interpretation is difficult as most effects flow through (unobserved) gene regulatory networks. Can we gain insight by linking to modern Perturb-seq data?
www.biorxiv.org/content/10.1...
Causal modeling of gene effects from regulators to programs to traits: integration of genetic associations and Perturb-seq
Genetic association studies provide a unique tool for identifying causal links from genes to human traits and diseases. However, it is challenging to determine the biological mechanisms underlying mos...
www.biorxiv.org
January 27, 2025 at 7:19 PM
I posted a couple days ago about our new paper on building causal graphs from genetic associations + Perturb-seq.
Here I want to expand on the value of using DIRECTIONAL information contained in LoF burden tests.🧵
[work led by @minetoota.bsky.social ]
bsky.app/profile/jkpr...
Here I want to expand on the value of using DIRECTIONAL information contained in LoF burden tests.🧵
[work led by @minetoota.bsky.social ]
bsky.app/profile/jkpr...
Excited to see this out. It looks great. Also nicely highlights how useful OA books can be. There's a bunch of chapters here I'd definitely think of assigning to upper division students, without the guilt of asking them to buy a book.
bsky.app/profile/jkpr...
bsky.app/profile/jkpr...
I'm delighted to release the first half of my new textbook in human genetics:
web.stanford.edu/group/pritch...
"An Owner's Guide to the Human Genome: an introduction to human population genetics, variation and disease"
web.stanford.edu/group/pritch...
"An Owner's Guide to the Human Genome: an introduction to human population genetics, variation and disease"
An Owner's Guide to the Human Genome
An Owner's Guide to the Human Genome
web.stanford.edu
October 1, 2023 at 11:57 PM
Excited to see this out. It looks great. Also nicely highlights how useful OA books can be. There's a bunch of chapters here I'd definitely think of assigning to upper division students, without the guilt of asking them to buy a book.
bsky.app/profile/jkpr...
bsky.app/profile/jkpr...
Check out this delightfully devious trailer for The Best of @agatha-vile.bsky.social ! www.youtube.com/watch?v=jkPr...
FULL TRAILER - The Best Of Agatha Vile
YouTube video by FireBlast Studios
www.youtube.com
August 2, 2025 at 12:55 AM
Check out this delightfully devious trailer for The Best of @agatha-vile.bsky.social ! www.youtube.com/watch?v=jkPr...
I'm starting to poke around this new textbook from @jkpritch.bsky.social
A fantastic resource for graduate students in human genetics. Thanks for sharing online!
bsky.app/profile/jkpr...
A fantastic resource for graduate students in human genetics. Thanks for sharing online!
bsky.app/profile/jkpr...
I'm delighted to release the first half of my new textbook in human genetics:
web.stanford.edu/group/pritch...
"An Owner's Guide to the Human Genome: an introduction to human population genetics, variation and disease"
web.stanford.edu/group/pritch...
"An Owner's Guide to the Human Genome: an introduction to human population genetics, variation and disease"
An Owner's Guide to the Human Genome
An Owner's Guide to the Human Genome
web.stanford.edu
December 11, 2023 at 2:47 PM
I'm starting to poke around this new textbook from @jkpritch.bsky.social
A fantastic resource for graduate students in human genetics. Thanks for sharing online!
bsky.app/profile/jkpr...
A fantastic resource for graduate students in human genetics. Thanks for sharing online!
bsky.app/profile/jkpr...
Here's the explainer thread from the preprint, but we also added a few new analyses (read on below).
bsky.app/profile/jkpr...
bsky.app/profile/jkpr...
Our latest preprint revisits the classic model of mutation-selection balance.
Do human recessive genes fit Haldane's 100-year old model?
This work is by the wonderful @jonj-udd.bsky.social, and co-mentored by @jeffspence.github.io
www.biorxiv.org/content/10.6...
Do human recessive genes fit Haldane's 100-year old model?
This work is by the wonderful @jonj-udd.bsky.social, and co-mentored by @jeffspence.github.io
www.biorxiv.org/content/10.6...
Allele Frequencies at Recessive Disease Genes are Mainly Determined by Pleiotropic Effects in Heterozygotes
The classic theory of mutation-selection balance predicts the equilibrium frequency of genetic variation under negative selection. The model predicts a simple relationship between the total frequency ...
www.biorxiv.org
June 22, 2026 at 7:11 PM
Here's the explainer thread from the preprint, but we also added a few new analyses (read on below).
bsky.app/profile/jkpr...
bsky.app/profile/jkpr...
For example, @minetoota.bsky.social used direction-of-effect estimates from LoF burden tests to build out causal graphs!
bsky.app/profile/jkpr...
4/n
bsky.app/profile/jkpr...
4/n
GWAS has been an incredible discovery tool for human genetics: it regularly identifies *causal* links from 1000s of SNPs to any given trait. But mechanistic interpretation is usually difficult.
Our latest work on causal models for this is out yesterday:
www.nature.com/articles/s41...
A short🧵:
Our latest work on causal models for this is out yesterday:
www.nature.com/articles/s41...
A short🧵:
Causal modelling of gene effects from regulators to programs to traits - Nature
Approaches combining genetic association and Perturb-seq data that link genetic variants to functional programs to traits are described.
www.nature.com
January 6, 2026 at 2:30 AM
For example, @minetoota.bsky.social used direction-of-effect estimates from LoF burden tests to build out causal graphs!
bsky.app/profile/jkpr...
4/n
bsky.app/profile/jkpr...
4/n
Here is an excellent example of how valuable perturbation experiments that can only scale in a single cell-line can be. This is K562 btw with some absolutely insane genomic rearrangements.
bsky.app/profile/jkpr...
bsky.app/profile/jkpr...
Modern GWAS can identify 1000s of significant hits but it can be hard to turn this into biological insight. What key cellular functions link genetic variation to disease?
I'm very excited to present our new work combining associations and Perturb-seq to build interpretable causal graphs! A 🧵
I'm very excited to present our new work combining associations and Perturb-seq to build interpretable causal graphs! A 🧵
January 28, 2025 at 1:18 AM
Here is an excellent example of how valuable perturbation experiments that can only scale in a single cell-line can be. This is K562 btw with some absolutely insane genomic rearrangements.
bsky.app/profile/jkpr...
bsky.app/profile/jkpr...
🎬 It all started with one cookie...
No one thought it would become an office scandal. Until someone took the last one. JKPR's take on the viral Netflix Documentary trend. Based on actual events. 🍪 Who's guilty? #CookieGate
#NetflixDocumentary #OfficeMystery #JKPR #Reels #Trending
No one thought it would become an office scandal. Until someone took the last one. JKPR's take on the viral Netflix Documentary trend. Based on actual events. 🍪 Who's guilty? #CookieGate
#NetflixDocumentary #OfficeMystery #JKPR #Reels #Trending
August 14, 2026 at 6:53 PM
🎬 It all started with one cookie...
No one thought it would become an office scandal. Until someone took the last one. JKPR's take on the viral Netflix Documentary trend. Based on actual events. 🍪 Who's guilty? #CookieGate
#NetflixDocumentary #OfficeMystery #JKPR #Reels #Trending
No one thought it would become an office scandal. Until someone took the last one. JKPR's take on the viral Netflix Documentary trend. Based on actual events. 🍪 Who's guilty? #CookieGate
#NetflixDocumentary #OfficeMystery #JKPR #Reels #Trending
✨ Meet Jaden, our newest Fall intern at JKPR! ✨ He’s already jumping into the mix, bringing fresh ideas, good vibes… and yes, a few bloopers along the way 🤭🍂 We love the energy he brings to the team. Welcome, Jaden — we can’t wait to see all you’ll do this season!
September 30, 2025 at 1:11 PM
✨ Meet Jaden, our newest Fall intern at JKPR! ✨ He’s already jumping into the mix, bringing fresh ideas, good vibes… and yes, a few bloopers along the way 🤭🍂 We love the energy he brings to the team. Welcome, Jaden — we can’t wait to see all you’ll do this season!
💕 Love is in the air at JKPR! 💕
Our team is getting into the Valentine’s Day spirit with sweet treats, festive vibes, and love for what we do! 💖 Whether it’s spreading kindness or crafting amazing PR magic, we’re feeling the love today. Wishing you a day of joy and maybe a little chocolate! 🍫✨
Our team is getting into the Valentine’s Day spirit with sweet treats, festive vibes, and love for what we do! 💖 Whether it’s spreading kindness or crafting amazing PR magic, we’re feeling the love today. Wishing you a day of joy and maybe a little chocolate! 🍫✨
February 11, 2025 at 1:02 PM
💕 Love is in the air at JKPR! 💕
Our team is getting into the Valentine’s Day spirit with sweet treats, festive vibes, and love for what we do! 💖 Whether it’s spreading kindness or crafting amazing PR magic, we’re feeling the love today. Wishing you a day of joy and maybe a little chocolate! 🍫✨
Our team is getting into the Valentine’s Day spirit with sweet treats, festive vibes, and love for what we do! 💖 Whether it’s spreading kindness or crafting amazing PR magic, we’re feeling the love today. Wishing you a day of joy and maybe a little chocolate! 🍫✨
⚽️🏆 The World Cup spirit has officially arrived at JKPR!
The JKPR team stepped up to the table for the 2026 World Cup Foosball Tournament - bringing strategy, teamwork, and a little friendly competition. 🌎🔥
The JKPR team stepped up to the table for the 2026 World Cup Foosball Tournament - bringing strategy, teamwork, and a little friendly competition. 🌎🔥
July 19, 2026 at 10:32 PM
⚽️🏆 The World Cup spirit has officially arrived at JKPR!
The JKPR team stepped up to the table for the 2026 World Cup Foosball Tournament - bringing strategy, teamwork, and a little friendly competition. 🌎🔥
The JKPR team stepped up to the table for the 2026 World Cup Foosball Tournament - bringing strategy, teamwork, and a little friendly competition. 🌎🔥
We can't wait to see all that she'll accomplish this summer. Welcome to JKPR, Melissa!
#JKPR #SummerIntern #TeamJKPR #WelcomeMelissa
#JKPR #SummerIntern #TeamJKPR #WelcomeMelissa
June 11, 2026 at 10:25 PM
We can't wait to see all that she'll accomplish this summer. Welcome to JKPR, Melissa!
#JKPR #SummerIntern #TeamJKPR #WelcomeMelissa
#JKPR #SummerIntern #TeamJKPR #WelcomeMelissa
Say hello to Brynn 🌸 Our newest Spring Intern has officially arrived at JKPR - bringing fresh energy, sharp instincts, and a passion for storytelling.
From day one, she’s diving in, learning fast, and already making her mark. Spring just got a little brighter. ✨
#meettheintern
From day one, she’s diving in, learning fast, and already making her mark. Spring just got a little brighter. ✨
#meettheintern
March 26, 2026 at 12:26 PM
Say hello to Brynn 🌸 Our newest Spring Intern has officially arrived at JKPR - bringing fresh energy, sharp instincts, and a passion for storytelling.
From day one, she’s diving in, learning fast, and already making her mark. Spring just got a little brighter. ✨
#meettheintern
From day one, she’s diving in, learning fast, and already making her mark. Spring just got a little brighter. ✨
#meettheintern
Meet Nina ✨ We’re excited to welcome our new intern to JKPR! Fresh perspective, sharp instincts, and ready to dive in — we can’t wait to see the ideas, energy, and creativity she brings to the table.
Here’s to learning, growing, and building something great together. 💼💫 #NewIntern #PublicRelations
Here’s to learning, growing, and building something great together. 💼💫 #NewIntern #PublicRelations
February 19, 2026 at 10:36 PM
Meet Nina ✨ We’re excited to welcome our new intern to JKPR! Fresh perspective, sharp instincts, and ready to dive in — we can’t wait to see the ideas, energy, and creativity she brings to the table.
Here’s to learning, growing, and building something great together. 💼💫 #NewIntern #PublicRelations
Here’s to learning, growing, and building something great together. 💼💫 #NewIntern #PublicRelations
The JKPR elves are officially on the move 🎄✨
Bundt cakes in hand, spreading sweet cheer to everyone on the Nice List — our amazing media friends. Thank you for another year of great stories, partnerships, and support. Happy holidays from all of us at JKPR! 🍰🎁
#JKPR #JKPRElves #NiceListOnly
#JKPR #JKPRElves #NiceListOnly
December 19, 2025 at 6:08 PM
The JKPR elves are officially on the move 🎄✨
Bundt cakes in hand, spreading sweet cheer to everyone on the Nice List — our amazing media friends. Thank you for another year of great stories, partnerships, and support. Happy holidays from all of us at JKPR! 🍰🎁
#JKPR #JKPRElves #NiceListOnly
#JKPR #JKPRElves #NiceListOnly
The JKPR elves are hard at work 🎄✨
Bundt cakes? Checked.
Naughty & Nice lists? Double-checked.
Reindeer ready? You bet. 🦌
Here’s Jaden, Sofia & Lauren spreading holiday cheer—singing it loud and proud—as we get ready for today’s annual JKPR Bundt Cake deliveries. Let the festive fun begin!
Bundt cakes? Checked.
Naughty & Nice lists? Double-checked.
Reindeer ready? You bet. 🦌
Here’s Jaden, Sofia & Lauren spreading holiday cheer—singing it loud and proud—as we get ready for today’s annual JKPR Bundt Cake deliveries. Let the festive fun begin!
December 18, 2025 at 6:25 PM
The JKPR elves are hard at work 🎄✨
Bundt cakes? Checked.
Naughty & Nice lists? Double-checked.
Reindeer ready? You bet. 🦌
Here’s Jaden, Sofia & Lauren spreading holiday cheer—singing it loud and proud—as we get ready for today’s annual JKPR Bundt Cake deliveries. Let the festive fun begin!
Bundt cakes? Checked.
Naughty & Nice lists? Double-checked.
Reindeer ready? You bet. 🦌
Here’s Jaden, Sofia & Lauren spreading holiday cheer—singing it loud and proud—as we get ready for today’s annual JKPR Bundt Cake deliveries. Let the festive fun begin!
🍁 Meet Annalyse, our new Fall intern at JKPR! ✨
She’s bringing curiosity, creativity, and a true passion for PR — eager to dive into media, strategy, and storytelling that makes an impact. 🎤💡
We can’t wait to see what she’ll create and learn this season with the team. Welcome, Annalyse! 🌟
We can’t wait to see what she’ll create and learn this season with the team. Welcome, Annalyse! 🌟
November 3, 2025 at 6:40 PM
🍁 Meet Annalyse, our new Fall intern at JKPR! ✨
She’s bringing curiosity, creativity, and a true passion for PR — eager to dive into media, strategy, and storytelling that makes an impact. 🎤💡
We can’t wait to see what she’ll create and learn this season with the team. Welcome, Annalyse! 🌟
We can’t wait to see what she’ll create and learn this season with the team. Welcome, Annalyse! 🌟
🎃 The JKPR team is back at it — decking out the office with treats, tricks, and plenty of Halloween spirit! 👻💀🕸️
Who says PR can’t be a little spooky? 😉
#JKPR #OfficeVibes #HalloweenFun #SpookySeason #TeamJKPR
Who says PR can’t be a little spooky? 😉
#JKPR #OfficeVibes #HalloweenFun #SpookySeason #TeamJKPR
October 30, 2025 at 5:36 PM
🎃 The JKPR team is back at it — decking out the office with treats, tricks, and plenty of Halloween spirit! 👻💀🕸️
Who says PR can’t be a little spooky? 😉
#JKPR #OfficeVibes #HalloweenFun #SpookySeason #TeamJKPR
Who says PR can’t be a little spooky? 😉
#JKPR #OfficeVibes #HalloweenFun #SpookySeason #TeamJKPR
🍂✨ Fall vibes are in full swing at JKPR! Our team got the office pumpkin-ready 🎃, added cozy plushies, and sprinkled a little autumn magic everywhere. Who else is feeling the October energy? 🍁 #FallFeels #OfficeVibes #JKPRLife #PumpkinSeason #CozyCorners
October 10, 2025 at 8:39 PM
🍂✨ Fall vibes are in full swing at JKPR! Our team got the office pumpkin-ready 🎃, added cozy plushies, and sprinkled a little autumn magic everywhere. Who else is feeling the October energy? 🍁 #FallFeels #OfficeVibes #JKPRLife #PumpkinSeason #CozyCorners