NOVO VÍDEO
Enfim chegou a hora de zerar e analisar o sofrido Mortal Kombat Mythologies SubZero no Zerando64
www.youtube.com/watch?v=jmml...
Enfim chegou a hora de zerar e analisar o sofrido Mortal Kombat Mythologies SubZero no Zerando64
www.youtube.com/watch?v=jmml...
May 13, 2025 at 9:14 PM
NOVO VÍDEO
Enfim chegou a hora de zerar e analisar o sofrido Mortal Kombat Mythologies SubZero no Zerando64
www.youtube.com/watch?v=jmml...
Enfim chegou a hora de zerar e analisar o sofrido Mortal Kombat Mythologies SubZero no Zerando64
www.youtube.com/watch?v=jmml...
Hey everyone on #bloodsky (🩸🧬), go check out this amazing paper from @mphartmann.bsky.social and @dblipka.bsky.social ‘s lab showing the roles of metabolic and oncofetal reprogramming in JMML. www.biorxiv.org/content/10.1...
It may not be how you imagined it! JMML always challenges our assumptions.
It may not be how you imagined it! JMML always challenges our assumptions.
February 9, 2024 at 7:27 PM
Support the YouTube upload too!
www.youtube.com/watch?v=JmMl...
www.youtube.com/watch?v=JmMl...
POPCORN Trailer
YouTube video by MoonToon
www.youtube.com
August 8, 2025 at 6:16 PM
Support the YouTube upload too!
www.youtube.com/watch?v=JmMl...
www.youtube.com/watch?v=JmMl...
Very happy and proud to see this story finally published! 🎉🥳
#epigenetics #hematology #jmml #leukemia
#epigenetics #hematology #jmml #leukemia
ONLINE FIRST ALERT!
Molecular #Plasticity Results in #Oncofetal #Reprogramming and Therapeutic Vulnerabilities in Juvenile Myelomonocytic Leukemia
aacrjournals.org/bloodcancerd...
@aacrjournals.bsky.social
#childhoodcancer
#epigenetics
#precisiononcology
Molecular #Plasticity Results in #Oncofetal #Reprogramming and Therapeutic Vulnerabilities in Juvenile Myelomonocytic Leukemia
aacrjournals.org/bloodcancerd...
@aacrjournals.bsky.social
#childhoodcancer
#epigenetics
#precisiononcology
December 6, 2025 at 1:07 AM
Very happy and proud to see this story finally published! 🎉🥳
#epigenetics #hematology #jmml #leukemia
#epigenetics #hematology #jmml #leukemia
Absolutely outstanding presentation by @ellouka.bsky.social at #ASH24 about the role of dendritic cells secreting GAS6 in maintaining LSCs in juvenile myelomonocytic leukemia #jmml #HemeSky
December 10, 2024 at 12:22 AM
Absolutely outstanding presentation by @ellouka.bsky.social at #ASH24 about the role of dendritic cells secreting GAS6 in maintaining LSCs in juvenile myelomonocytic leukemia #jmml #HemeSky
this is basically me
a girl in a school uniform is dancing on a tiled floor with jmml written on the bottom
ALT: a girl in a school uniform is dancing on a tiled floor with jmml written on the bottom
media.tenor.com
April 17, 2025 at 7:14 PM
this is basically me
To conclude our #RareDiseaseDay series, we spoke with @ellouka.bsky.social, a clinician scientist researching Paediatric Myelodysplastic Syndromes (MDS) and Juvenile Myelomonocytic Leukaemia (JMML). These are incredibly rare childhood cancers, with no current treatment options available. 🧪
Rare Disease Day 2025: Paediatric Leukaemias
YouTube video by MRC Weatherall Institute of Molecular Medicine
youtu.be
February 28, 2025 at 10:28 AM
To conclude our #RareDiseaseDay series, we spoke with @ellouka.bsky.social, a clinician scientist researching Paediatric Myelodysplastic Syndromes (MDS) and Juvenile Myelomonocytic Leukaemia (JMML). These are incredibly rare childhood cancers, with no current treatment options available. 🧪
to be fair to the translator, this is the first diagram in the original Chinese PDF. I have a degree in computer science and can read Chinese and certainly have no idea what's going on here.
April 22, 2026 at 11:12 AM
to be fair to the translator, this is the first diagram in the original Chinese PDF. I have a degree in computer science and can read Chinese and certainly have no idea what's going on here.
Multi-omics integration reveals risk-associated gene expression signatures, identifying CD52 as a potential therapeutic target for high-risk JMML.
Anti-CD52 treatment depletes JMML stem cells and disrupts disease propagation in a JMML PDX model.
Anti-CD52 treatment depletes JMML stem cells and disrupts disease propagation in a JMML PDX model.
December 6, 2025 at 12:59 AM
Multi-omics integration reveals risk-associated gene expression signatures, identifying CD52 as a potential therapeutic target for high-risk JMML.
Anti-CD52 treatment depletes JMML stem cells and disrupts disease propagation in a JMML PDX model.
Anti-CD52 treatment depletes JMML stem cells and disrupts disease propagation in a JMML PDX model.
RAS-pathway mutations induce fetal-like gene expression programs in a JMML mouse model, suggesting RAS-driven oncofetal reprogramming in murine JMML stem cells.
December 6, 2025 at 12:59 AM
RAS-pathway mutations induce fetal-like gene expression programs in a JMML mouse model, suggesting RAS-driven oncofetal reprogramming in murine JMML stem cells.
A big thank you to Elliot for organizing this great meeting every year at #ASH! It’s always fun to be there and lots of interesting talks. #JMML #HemeSky
@dblipka.bsky.social closing out the Alex’s Lemonade Stand Foundation JMML Summit by reminding us that these kids really are 1 in a million
(also featuring Eliot Stieglitz’s head). Phenomenal talks today
(also featuring Eliot Stieglitz’s head). Phenomenal talks today
December 7, 2024 at 12:53 AM
#MedSky🧪 #ImmunoSky Patients with inherited CBL mutation & somatic loss-of-heterozygosity are known to develop spontaneously resolving JMML and to suffer from #autoinflammation, particularly #vasculitis …
www.jci.org/articles/vie...
www.jci.org/articles/vie...
October 18, 2024 at 7:09 PM
#MedSky🧪 #ImmunoSky Patients with inherited CBL mutation & somatic loss-of-heterozygosity are known to develop spontaneously resolving JMML and to suffer from #autoinflammation, particularly #vasculitis …
www.jci.org/articles/vie...
www.jci.org/articles/vie...
Warming up for #ASH24 at the JMML summit. @ellouka.bsky.social presenting exciting multiomic single-cell and functional studies highlighting the role of HSC-cDC interactions in altering the leukaemia microenvironment.
December 7, 2024 at 2:02 AM
Warming up for #ASH24 at the JMML summit. @ellouka.bsky.social presenting exciting multiomic single-cell and functional studies highlighting the role of HSC-cDC interactions in altering the leukaemia microenvironment.
JMML stem cells aren’t epigenetically “stuck” in a fetal state.
They mature postnatally—yet show striking transcriptional plasticity, with oncofetal reprogramming in high-risk disease, challenging the classic “maturation block” model.
doi.org/10.1158/2643...
#JMML #epigenetics #hematology #cancer
They mature postnatally—yet show striking transcriptional plasticity, with oncofetal reprogramming in high-risk disease, challenging the classic “maturation block” model.
doi.org/10.1158/2643...
#JMML #epigenetics #hematology #cancer
Molecular Plasticity Results in Oncofetal Reprogramming and Therapeutic Vulnerabilities in Juvenile Myelomonocytic Leukemia
AbstractPersistent fetal gene expression in childhood neoplasms is usually explained by a maturation block originating in the prenatal phase. In contrast, reactivation of fetal genes in adult malignan...
doi.org
February 4, 2026 at 6:28 PM
JMML stem cells aren’t epigenetically “stuck” in a fetal state.
They mature postnatally—yet show striking transcriptional plasticity, with oncofetal reprogramming in high-risk disease, challenging the classic “maturation block” model.
doi.org/10.1158/2643...
#JMML #epigenetics #hematology #cancer
They mature postnatally—yet show striking transcriptional plasticity, with oncofetal reprogramming in high-risk disease, challenging the classic “maturation block” model.
doi.org/10.1158/2643...
#JMML #epigenetics #hematology #cancer
Great to meet friends and colleagues at this year’s EWOG-MDS meeting in Berlin. We had great discussions and developed new project ideas and collaborations with the aim of improving risk stratification and patient care for JMML patients.
#jmml #ewogmds #precisionmedicine www.ewogberlin2025.org
#jmml #ewogmds #precisionmedicine www.ewogberlin2025.org
On the Verge to Malignancy: Cytopenia and Beyond - Ewog Symposium
On the Verge to Malignancy:
Cytopenia and Beyond
International Symposium on
bone marrow failure, predisposition,
MDS and MPD in the Young
Dear colleagues and friends,
we are pleased to wel...
www.ewogberlin2025.org
September 19, 2025 at 5:07 PM
Great to meet friends and colleagues at this year’s EWOG-MDS meeting in Berlin. We had great discussions and developed new project ideas and collaborations with the aim of improving risk stratification and patient care for JMML patients.
#jmml #ewogmds #precisionmedicine www.ewogberlin2025.org
#jmml #ewogmds #precisionmedicine www.ewogberlin2025.org
Hey everyone on #bloodsky (🩸🧬), go check out this amazing paper from @mphartmann.bsky.social and @dblipka.bsky.social ‘s lab showing the roles of metabolic and oncofetal reprogramming in JMML. www.biorxiv.org/content/10.1...
It may not be how you imagined it! JMML always challenges our assumptions.
It may not be how you imagined it! JMML always challenges our assumptions.
February 9, 2024 at 3:42 PM
Hey everyone on #bloodsky (🩸🧬), go check out this amazing paper from @mphartmann.bsky.social and @dblipka.bsky.social ‘s lab showing the roles of metabolic and oncofetal reprogramming in JMML. www.biorxiv.org/content/10.1...
It may not be how you imagined it! JMML always challenges our assumptions.
It may not be how you imagined it! JMML always challenges our assumptions.
Here’s our labs latest work on CAR Ts for treatment of JMML. Great work from Juwita Werner and Alex Lee 🎉
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Cellular immunotherapy targeting CLL-1 for juvenile myelomonocytic leukemia - Nature Communications
JMML is an aggressive hematologic malignancy with myeloproliferative characteristics affecting young children. Here the authors report that C-type lectin-like molecule-1 (CLL-1) is upregulated in JMML...
www.nature.com
May 1, 2025 at 9:02 PM
Here’s our labs latest work on CAR Ts for treatment of JMML. Great work from Juwita Werner and Alex Lee 🎉
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Fetal HSC signatures are enriched in patients without detectable JMML driver mutations at birth.
December 6, 2025 at 12:59 AM
Fetal HSC signatures are enriched in patients without detectable JMML driver mutations at birth.
Juvenile Myelomonocytic Leukemia(JMML): Maria and Joseph's Story
A mother who refused to give up and three transplants later, Joseph is full of life.https://bmtinfonet.org/story/juvenile-myelomonocytic-leukemiajmml-maria-and-josephs-story
A mother who refused to give up and three transplants later, Joseph is full of life.https://bmtinfonet.org/story/juvenile-myelomonocytic-leukemiajmml-maria-and-josephs-story
February 3, 2025 at 10:27 PM
Juvenile Myelomonocytic Leukemia(JMML): Maria and Joseph's Story
A mother who refused to give up and three transplants later, Joseph is full of life.https://bmtinfonet.org/story/juvenile-myelomonocytic-leukemiajmml-maria-and-josephs-story
A mother who refused to give up and three transplants later, Joseph is full of life.https://bmtinfonet.org/story/juvenile-myelomonocytic-leukemiajmml-maria-and-josephs-story
The postnatal maturation state of JMML stem cells challenges the universality of the maturation block model in pediatric malignancies.
December 6, 2025 at 12:59 AM
The postnatal maturation state of JMML stem cells challenges the universality of the maturation block model in pediatric malignancies.
@dblipka.bsky.social closing out the Alex’s Lemonade Stand Foundation JMML Summit by reminding us that these kids really are 1 in a million
(also featuring Eliot Stieglitz’s head). Phenomenal talks today
(also featuring Eliot Stieglitz’s head). Phenomenal talks today
December 6, 2024 at 10:14 PM
@dblipka.bsky.social closing out the Alex’s Lemonade Stand Foundation JMML Summit by reminding us that these kids really are 1 in a million
(also featuring Eliot Stieglitz’s head). Phenomenal talks today
(also featuring Eliot Stieglitz’s head). Phenomenal talks today
JMML epitypes are prognostic biomarkers in JMML.
Conservation of such disease-specific epigenetic signatures in HSC-like JMML stem cells and downstream immune cells suggests HSCs or early HSPCs as the cells-of-origin in JMML across JMML epitypes.
Conservation of such disease-specific epigenetic signatures in HSC-like JMML stem cells and downstream immune cells suggests HSCs or early HSPCs as the cells-of-origin in JMML across JMML epitypes.
December 6, 2025 at 12:59 AM
JMML epitypes are prognostic biomarkers in JMML.
Conservation of such disease-specific epigenetic signatures in HSC-like JMML stem cells and downstream immune cells suggests HSCs or early HSPCs as the cells-of-origin in JMML across JMML epitypes.
Conservation of such disease-specific epigenetic signatures in HSC-like JMML stem cells and downstream immune cells suggests HSCs or early HSPCs as the cells-of-origin in JMML across JMML epitypes.
Today's #LichBop is Psychedelic Porn Crumpets' "Pukebox"
"I'm on your side most of the time"
#VTuber #LichLife
music.youtube.com/watch?v=JMMl...
"I'm on your side most of the time"
#VTuber #LichLife
music.youtube.com/watch?v=JMMl...
Pukebox
YouTube video by Psychedelic Porn Crumpets - Topic
music.youtube.com
September 16, 2025 at 7:48 AM
Today's #LichBop is Psychedelic Porn Crumpets' "Pukebox"
"I'm on your side most of the time"
#VTuber #LichLife
music.youtube.com/watch?v=JMMl...
"I'm on your side most of the time"
#VTuber #LichLife
music.youtube.com/watch?v=JMMl...