Breaking the boundaries of affinity selection-mass spectrometry: From ligand screening to target-ligand interaction insights #JPharmAnal www.sciencedirect.com/science/arti...
Breaking the boundaries of affinity selection-mass spectrometry: From ligand screening to target-ligand interaction insights
Affinity selection mass spectrometry (AS-MS) has emerged as a powerful label-free technique for identifying and characterizing ligand-target interacti…
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February 24, 2026 at 9:21 PM
Breaking the boundaries of affinity selection-mass spectrometry: From ligand screening to target-ligand interaction insights #JPharmAnal www.sciencedirect.com/science/arti...
Integration of deep neural network modeling and LC-MS-based pseudo-targeted metabolomics to discriminate easily confused ginseng species #JPharmAnal www.sciencedirect.com/science/arti...
Integration of deep neural network modeling and LC-MS-based pseudo-targeted metabolomics to discriminate easily confused ginseng species
Metabolomics covers a wide range of applications in life sciences, biomedicine, and phytology. Data acquisition (to achieve high coverage and efficien…
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February 4, 2025 at 1:11 PM
Integration of deep neural network modeling and LC-MS-based pseudo-targeted metabolomics to discriminate easily confused ginseng species #JPharmAnal www.sciencedirect.com/science/arti...
Software-aided efficient identification of the components of compound formulae and their metabolites in rats by UHPLC/IM-QTOF-MS and an in-house high-definition MS2 library: Sishen formula as a case #JPharmAnal www.sciencedirect.com/science/arti...
Software-aided efficient identification of the components of compound formulae and their metabolites in rats by UHPLC/IM-QTOF-MS and an in-house high-definition MS2 library: Sishen formula as a case
Identifying the compound formulae-related xenobiotics in bio-samples is full of challenges. Conventional strategies always exhibit the insufficiencies…
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January 24, 2025 at 12:35 PM
Software-aided efficient identification of the components of compound formulae and their metabolites in rats by UHPLC/IM-QTOF-MS and an in-house high-definition MS2 library: Sishen formula as a case #JPharmAnal www.sciencedirect.com/science/arti...
FPS_P/N: A two-dimensional mass spectrometry utilization program with precursor ion determination for accurately distinguishing anthocyanin from other flavonoids #JPharmAnal www.sciencedirect.com/science/arti...
FPS_P/N: A two-dimensional mass spectrometry utilization program with precursor ion determination for accurately distinguishing anthocyanin from other flavonoids
Anthocyanins, a unique class of flavonoids with flavylium skeletons, are valued for antioxidant properties. However, distinguishing anthocyanins from …
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February 4, 2026 at 8:17 PM
FPS_P/N: A two-dimensional mass spectrometry utilization program with precursor ion determination for accurately distinguishing anthocyanin from other flavonoids #JPharmAnal www.sciencedirect.com/science/arti...
Decoding protein dynamics with limited proteolysis coupled to mass spectrometry: A comprehensive review #JPharmAnal www.sciencedirect.com/science/arti...
Decoding protein dynamics with limited proteolysis coupled to mass spectrometry: A comprehensive review
Proteins are indispensable to all biological systems and drive life processes through activities that are intricately linked to their three-dimensiona…
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January 5, 2026 at 1:19 PM
Decoding protein dynamics with limited proteolysis coupled to mass spectrometry: A comprehensive review #JPharmAnal www.sciencedirect.com/science/arti...
Recent advances in mass spectrometry-based bioanalytical methods for endogenous biomarkers analysis in transporter-mediated drug-drug interactions #JPharmAnal www.sciencedirect.com/science/arti...
Recent advances in mass spectrometry-based bioanalytical methods for endogenous biomarkers analysis in transporter-mediated drug-drug interactions
Drug-drug interactions (DDI) are a critical concern in drug development and clinical practice. A new molecular entity often requires numerous clinical…
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December 16, 2025 at 8:20 PM
Recent advances in mass spectrometry-based bioanalytical methods for endogenous biomarkers analysis in transporter-mediated drug-drug interactions #JPharmAnal www.sciencedirect.com/science/arti...
Screening of glycan biomarkers for early detection of colorectal cancer based on novel isotope labeling relative quantitative method #JPharmAnal #MassSpec www.sciencedirect.com/science/arti...
Screening of glycan biomarkers for early detection of colorectal cancer based on novel isotope labeling relative quantitative method
Colorectal cancer (CRC) is a prevalent gastrointestinal malignancy. However, the lack of diagnostic accuracy of traditional clinical serum biomarkers …
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December 16, 2025 at 8:19 PM
Screening of glycan biomarkers for early detection of colorectal cancer based on novel isotope labeling relative quantitative method #JPharmAnal #MassSpec www.sciencedirect.com/science/arti...
Lipidome atlas of human myometrium reveals distinctive lipid signatures associated with adenomyosis: Combination of high-coverage lipidomics and mass spectrometry imaging #JPharmAnal www.sciencedirect.com/science/arti...
Lipidome atlas of human myometrium reveals distinctive lipid signatures associated with adenomyosis: Combination of high-coverage lipidomics and mass spectrometry imaging
Adenomyosis is a common gynecological disease characterized by the invasion of endometrial glands and stroma into the myometrium of uterus, the pathol…
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October 6, 2025 at 6:37 PM
Lipidome atlas of human myometrium reveals distinctive lipid signatures associated with adenomyosis: Combination of high-coverage lipidomics and mass spectrometry imaging #JPharmAnal www.sciencedirect.com/science/arti...
Disorder of phospholipid metabolism in the renal cortex and medulla contributes to acute tubular necrosis in mice after cantharidin exposure using integrative lipidomics and spatial metabolomics #JPharmAnal #MassSpec www.sciencedirect.com/science/arti...
Disorder of phospholipid metabolism in the renal cortex and medulla contributes to acute tubular necrosis in mice after cantharidin exposure using integrative lipidomics and spatial metabolomics
Cantharidin (CTD), a natural compound used to treat multiple tumors in the clinic setting, has been limited due to acute kidney injury (AKI). However,…
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July 31, 2025 at 1:08 PM
Disorder of phospholipid metabolism in the renal cortex and medulla contributes to acute tubular necrosis in mice after cantharidin exposure using integrative lipidomics and spatial metabolomics #JPharmAnal #MassSpec www.sciencedirect.com/science/arti...
Strategy for cysteine-targeting covalent inhibitors screening using in-house database based LC-MS/MS and drug repurposing #JPharmAnal www.sciencedirect.com/science/arti...
Strategy for cysteine-targeting covalent inhibitors screening using in-house database based LC-MS/MS and drug repurposing
Targeted covalent inhibitors, primarily targeting cysteine residues, have attracted great attention as potential drug candidates due to good potency a…
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April 9, 2025 at 6:04 PM
Strategy for cysteine-targeting covalent inhibitors screening using in-house database based LC-MS/MS and drug repurposing #JPharmAnal www.sciencedirect.com/science/arti...
Targeted screening and profiling of massive components of colistimethate sodium by two-dimensional-liquid chromatography-mass spectrometry based on self-constructed compound database #JPharmAnal www.sciencedirect.com/science/arti...
Targeted screening and profiling of massive components of colistimethate sodium by two-dimensional-liquid chromatography-mass spectrometry based on self-constructed compound database
In-depth study of the components of polymyxins is the key to controlling the quality of this class of antibiotics. Similarities and variations of comp…
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February 17, 2025 at 6:55 PM
Targeted screening and profiling of massive components of colistimethate sodium by two-dimensional-liquid chromatography-mass spectrometry based on self-constructed compound database #JPharmAnal www.sciencedirect.com/science/arti...
Spatial metabolomics reveal metabolic alternations in the injured mice kidneys induced by triclocarban treatment #JPharmAnal #MassSpec www.sciencedirect.com/science/arti...
Spatial metabolomics reveal metabolic alternations in the injured mice kidneys induced by triclocarban treatment
Triclocarban (TCC) is a common antimicrobial agent that has been widely used in medical care. Given the close association between TCC treatment and me…
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December 24, 2024 at 7:35 PM
Spatial metabolomics reveal metabolic alternations in the injured mice kidneys induced by triclocarban treatment #JPharmAnal #MassSpec www.sciencedirect.com/science/arti...
Comparative study of trastuzumab modification analysis using mono/multi-epitope affinity technology with LC-QTOF-MS #JPharmAnal www.sciencedirect.com/science/arti...
Comparative study of trastuzumab modification analysis using mono/multi-epitope affinity technology with LC-QTOF-MS
Dynamic tracking analysis of monoclonal antibodies (mAbs) biotransformation in vivo is crucial, as certain modifications could inactivate the protein …
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December 19, 2024 at 7:12 PM
Comparative study of trastuzumab modification analysis using mono/multi-epitope affinity technology with LC-QTOF-MS #JPharmAnal www.sciencedirect.com/science/arti...