#JR-446
LightNews LightNews
newnews0320.bsky.social
【帰省ラッシュ】JRの年末年始の予約数が過去最高を更新
news.livedoor.com/article/deta...
JR各社によると、末年始期間の新幹線などの指定席の予約数は446万席で、前の年より17%増えて過去最高となった。東海道新幹線のピークは下りが28日、上りが1月4日で、「のぞみ」は全席指定席で運行される。
December 12, 2024 at 12:21 AM
npub1qspus6smkn8mcdxg5jflh50s69vdgtwsd5p74gmjpzp2qekn5duqfv5afj.momostr.pink.ap.brid.gy
📺 [ #GaMeTiMe ]
Victor Mesa Jr. 2-run homer to put the Rays back on top🔥
https://files.mastodon.social/cache/media_attachments/files/117/402/810/650/427/446/original/cc29a22edd3fa846.mp4
#PREDYX 🌐 #MLB
October 8, 2026 at 2:02 AM
baseballjeff1.bsky.social
R11: No. 326 - C Rod Barajas Jr.
R12: No. 356 - P Cody Delvecchio
R13: No. 386 - C Broedy Poppell
R14: No. 416 - P Trey Seeley
R15: No. 446 - OF Damian Bravo
R16: No. 476 - P Garrett Langrell
R17: No. 506 - P Luke Mensik
R18: No. 536 - P Cooper McGrath
R19: No. 566 - P Braydon Risley
July 15, 2025 at 2:44 AM
natumi-kaoru.fedibird.com.ap.brid.gy
いまから18日までは「秋の乗り放題パス」が利用可能ですよ
連続3日間全JR線普通列車（含快速・新快速・特快）乗り放題で7850円（1日あたり2616.7円）

詳細：https://www.jrkyushu-kippu.jp/fare/ticket/446
秋の乗り放題パス｜JR九州
JR九州のきっぷ詳細に関するページです。
www.jrkyushu-kippu.jp
October 4, 2026 at 2:29 PM
bigcases.bots.law
New filing: "Julia Hubbard v. Trammell Crow, Jr. (sex trafficking billionaire)"
Doc #446: Advisory to the Court

Download PDF | View Full Case

#CL67346920
July 7, 2026 at 3:06 AM
sushinateur.bsky.social
Heute wieder zurück zum leicht enttäuschenden Normalzustand ☺️

#ows899 🔎 4/5 (01:18)
⭐⭐⭐⭐
🔥 streak: 446
🧞 #owsgenius
puzzlist.com/onewordsearch
Robert Downey Jr. Relief
ALT: Robert Downey Jr. Relief
static.klipy.com
August 6, 2026 at 10:07 PM
47news.jp
JRの年末年始予約、17％増 旅客6社、9連休でピーク分散
JRの年末年始予約、17％増 旅客6社、9連休でピーク分散
　JR旅客6社は11日、年末年始（27日～2025年1月5日）の新幹線と在来線の指定席の予約数が10日時点で、前年度比17％増の446万席だったと発表した。9連休まで取れる曜日の並びが好調の要因とみて ...
www.47news.jp
December 11, 2024 at 9:21 AM
tokyo-days.bsky.social
ムコ多糖症 IIIB型向け新治療薬JR-446の臨床試験が始動#JR-446#MPS_IIIB#ライソゾーム病

新薬JR-446によるムコ多糖症IIIB型の治療を目指し、グローバル臨床試験がスタートしました。患者さんの新たな希望となることを期待しましょう。
ムコ多糖症 IIIB型向け新治療薬JR-446の臨床試験が始動
新薬JR-446によるムコ多糖症IIIB型の治療を目指し、グローバル臨床試験がスタートしました。患者さんの新たな希望となることを期待しましょう。
tokyo.publishing.3rd-in.co.jp
September 11, 2026 at 1:37 AM
new3rd.bsky.social
希少疾患ムコ多糖症IIIB型にJR-446がオーファンドラッグ指定#東京都#中央区#ムコ多糖症#JR-446#オーファンドラッグ

メディパルとJCRが共同開発中のJR-446が、欧州委員会からオーファンドラッグに指定されました。この進展が示す意味とは？
希少疾患ムコ多糖症IIIB型にJR-446がオーファンドラッグ指定
メディパルとJCRが共同開発中のJR-446が、欧州委員会からオーファンドラッグに指定されました。この進展が示す意味とは？
news.3rd-in.co.jp
June 24, 2025 at 6:47 AM
theouterhaven.net
Nintendo Entertainment Podcast – Episode 446 – Justice For Bowser Jr.! #NintendoEntertainmentPodcast #FireEmblem
Nintendo Entertainment Podcast – Episode 446 – Justice For Bowser Jr.!
The Nintendo Entertainment Podcast is back to its regularly scheduled format, and they’ll have plenty to talk about…despite SOMEONE not being here again. Just saying. First, Todd and Will break down their gaming exploits over the last few weeks. Todd has dove into Trails of the Sky First Chapter due to the “nudging” of a [...] The post Nintendo Entertainment Podcast – Episode 446 – Justice For Bowser Jr.! first appeared on The Outerhaven.
dlvr.it
September 26, 2025 at 1:06 PM
random-jays-hr.bsky.social
Vladimir Guerrero Jr. 💥 HOMER! 🏠
Off José Urquidy | 3 inning | April 29, 2022

Pitch: Sweeper 80.5 mph (2558 rpm)
Hit: 114.4 mph | 446 ft | 20°
July 26, 2025 at 10:31 PM
discover.holos.social.web.brid.gy
Resistbot (@resistbot@mastodon.social)
🔥 Top Campaigns, Last 24 Hours:1️⃣ “Support Rep Cohen's articles of impeachment: your oath requires it” (+876)2️⃣ “Defend Congressional Spending Authority — Stop Unlawful Rescissions Now” (+831)3️⃣ “Clean House at the Department of Retribution” (+477)4️⃣ “Remove Secretary Robert F. Kennedy Jr. Immediately” (+446)5️⃣ “Investigate Trump's Stock Trading and Hold His Administration Accountable” (+371) https://resist.bot/petitions
mastodon.social
September 28, 2026 at 4:56 AM
mikemaher.bsky.social
💣 HR LEANS

⚾ Drake Baldwin (+480 ProphetX)
⚾ Danny Jansen (+730 FD)
⚾ Jazz Chisholm Jr. (+525 BetRivers)
⚾ Jordan Walker (+713 Novig)
⚾ Eugenio Suarez (+446 Novig)
⚾ Christian Walker (+456 Kalshi)
⚾ Oneil Cruz (+456 Kalshi)
⚾ Bryce Harper (+488 Kalshi)
⚾ Kyle Stowers
April 25, 2026 at 4:55 PM
rsnstats.com
Top #RedSox SLG at
#Angels Stadium
Since 2010
Min. 40 At-Bats:

1. J.D. Martinez, .809
2. Mookie Betts, .677
3. Rafael Devers, .446 <<<
4. Xander Bogaerts, .427
5. David Ortiz, .419
6. Brock Holt, .373
7. Jackie Bradley Jr., .328
8. Jacoby Ellsbury, .326
9. Dustin Pedroia, .272
April 6, 2024 at 3:25 AM
47news.jp
JRの年末年始予約、17％増 旅客6社、9連休でピーク分散
JRの年末年始予約、17％増 旅客6社、9連休でピーク分散
　JR旅客6社は11日、年末年始（27日～2025年1月5日）の新幹線と在来線の指定席の予約数が10日時点で、前年度比17％増の446万席だったと発表した。9連休まで取れる曜日の並びが好調の要因とみて ...
www.47news.jp
December 11, 2024 at 9:16 AM
tovahr.bsky.social
youtube.com/watch?v=Q8Ie...

MLK Community Hospital in Watts, Los Angeles is one of 446 hospitals nationwide at high risk of closure under Trump's Medicaid cuts. The hospital serves a predominantly Black and Latino community — 75% of its revenue comes from Medi-Cal.
Trump Named It the 'Big Beautiful Bill'. It's Closing the Hospital Named After MLK Jr.
YouTube video by The Logical Leftist
youtube.com
May 6, 2026 at 1:15 AM
reggieisdead.bsky.social
For all my people in the Philly area that need warmth during this weather/possible snowstorm…here’s some warming centers around the city
DAYTIME WARMING CENTERS • Blackwell Regional Library 125 South 52nd St. 19139 9am-9pm • Bustleton Library 10199 Bustleton Ave. 19116 9am-9pm • Haddington Library 446 North 65' St. 19151 9am-9pm • Kensington Library 104 West Dauphin St. 19133 9am-9pm • Lillian Marrero Library 601 West Lehigh Ave. 19133 9am-9pm • Logan Library 1333 Wagner St. 19141 9am-9pm • Nicetown/ Tioga Library 3720 North Broad St. 19140 9am-9pm • Northeast Regional Library 2228 Cottman Ave. 19149 9am-9pm • Parkway Central Library 1901 Vine St. 19103 9am-9pm • Queen Memorial Library 1201 S 23'd St. 19146 *Enter on Federal St. 9am-9pm • Walnut St. West Library 201 South 40th St. 19104 9am-9pm NIGHTTIME WARMING CENTERS • DiSilvestro Rec Center 1701 S 15th St 19145 9pm-9am • Dr Martin Luther King Jr Rec Center 2101 Cecil B. Moore Ave 9pm-9am • Scanlon Rec Center 1099 E Venango 9pm-9am
January 24, 2026 at 10:41 PM
tamosan.bsky.social
ほうほう、珈琲野郎さんの横くらいね：【開店】マシマシスタンド安城緑町店 – 開店閉店.com https://kaiten-heiten-24.com/mashi-mashi-anjomidoricho/
【開店】マシマシスタンド安城緑町店 | 開店閉店.com
愛知県安城市 2024年12月12日（木）オープン 住所 〒446-0055 愛知県安城市緑町1丁目8−18 電話番号 アクセス JR東海道本線 東刈谷駅 営業時間 平日11:30〜14:30〜22:00（L.O21:3...
kaiten-heiten-24.com
December 13, 2024 at 7:43 AM
boxtoppers.bsky.social
😖 Sunday’s lowest Box-Toppers game scores
By pitchers:
-14.9 — Brandon Young #Orioles 4.1IP 9H 7R 0BB 4K L
By batters:
-5.0 — Ronald Acuña Jr. #Braves 0‑5 3K
-5.0 — Kyle Schwarber #Phillies 0‑5 3K
www.box-toppers.com/blog/2025/7/...
Lowest Box-Toppers game scores Out of 446 total players Sunday, 124 pitchers -14.9—Brandon Young, Orioles (4.1IP 9H 7R 0BB 4K L vs. MIA) -12.0—Jesse Chavez, Braves -11.0—José Berríos, Blue Jays -10.0—Jackson Rutledge, Nationals Lowest Box-Toppers game scores by batters Out of 322 total batters Sunday -5.0—Ronald Acuña Jr., Braves 0-5 3K -5.0—Kyle Schwarber, Phillies 0-5 3K -5.0—Corbin Carroll, Diamondbacks 0-5 2K -5.0—Rafael Devers, Giants 0-5 2K -5.0—Tommy Edman, Dodgers 0-5 2K -5.0—Francisco Lindor, Mets 0-5 2K -5.0—Josh Smith, Rangers 0-5 2K -5.0—Lenyn Sosa, White Sox 0-5 2K
July 14, 2025 at 6:38 PM
tamosan.bsky.social
あらら、三河安城のあそこ閉まるのか（昔も一度閉まってたよーな？）：【閉店】松坂屋 安城ギフトショップ – 開店閉店.com https://kaiten-heiten-24.com/matsuzakaya-anjo-gs/
【閉店】松坂屋 安城ギフトショップ | 開店閉店.com
愛知県安城市 2025年1月31日（金）閉店 情報のご提供は さま　ありがとうございました。 住所 〒446-0059 愛知県安城市三河安城本町1丁目29−1 アクセス JR三河安城駅より西へ徒歩約7分 営業時間 定休日...
kaiten-heiten-24.com
October 17, 2024 at 1:33 PM
antoniodatsch.bsky.social
privatização de 200 escolas, mensagens do estado todo e saibam que vocês têm o meu compromisso de votar contra esse projeto na Alep e trabalhar para que essa proposta desastrosa seja barrada! Ratinho Jr. quer acabar com a educação pública, mas nós vamos lutar contra
www.instagram.com/reel/C7ZT0zt...
Dep. Arilson Chiorato on Instagram: "A população do Paraná está indignada com a privatização de 200 escolas! Tenho recebido inúmeras mensagens do estado todo e saibam que vocês tem o meu compromisso d...
446 likes, 137 comments - arilsonchiorato on May 25, 2024: "A população do Paraná está indignada com a privatização de 200 escolas! Tenho recebido inúmeras mensagens do estado todo e saibam ...".
www.instagram.com
May 27, 2024 at 6:07 PM
bigcases.bots.law
New filing: "U.S. v. Trump (mar-a-lago docs)"
Doc #451: PAPERLESS Minute Entry for Hearing held before Judge Aileen M. Cannon on April 12, 2024. The Court heard argument on Motions filed by Defendants Nauta and De Oliveira…

[full entry below 👇]

[Download PDF] | [View Full Case]

#CL67490070
The entry's text: PAPERLESS Minute Entry for Hearing held before Judge Aileen M. Cannon on April 12, 2024. The Court heard argument on Motions filed by Defendants Nauta and De Oliveira 323 446 448 . The parties also presented argument on the need for continued sealing of certain grand jury materials. Orders to follow. Total time in court: 2 hours 5 minutes. Attorney Appearances: Jay I. Bratt, David Harbach, Stanley Woodward, Sasha Dadan, Larry Donald Murrell, Jr., John S. Irving, Lazaro Fields. Other Appearances: Defendants Waltine Nauta, Carlos De Oliveira. Court Reporter: Laura Melton, 305-523-5633 / Laura_Melton@flsd.uscourts.gov. (jf01) (Entered: 04/12/2024)
April 13, 2024 at 1:28 AM
kylecbarry.bsky.social
Not as fun as his Shelby County takedown, but Justice Eddins' opinion is also a tour de force on how state constitutions can and often do provide stronger civil rights than SCOTUS precedent -- looking to distinct text, history, clauses, local values, & interpretive methods bsky.app/profile/mjsd...
A state high court interprets a state constitution its own way. State v. Wilson, 154 Hawaiʻi 8, 14, 543 P.3d 440, 446 (2024). This court has long understood federalism principles and operated with a no lock-stepping approach. William J. Brennan, Jr., State Constitutions and the Protection of Individual Rights, 90 Harv. L. Rev. 489, 499-500 (1977) (shout out to the Hawaiʻi Supreme Court). Our state constitutional provisions offer greater rights protection than federal *** counterparts. See, e.g., State v. Texeira, 50 Haw. 138, 142 n.2, 433 P.2d 593, 597 n.2 (1967). This court may interpret Hawaiʻi’s Establishment Clause broader than the federal Establishment Clause. The Hawaiʻi Constitution’s Preamble reflects Hawaiʻi’s multi-cultural and multi-religious character. “We, the people of Hawaii, grateful for Divine Guidance, and mindful of our Hawaiian heritage and uniqueness as an island State, dedicate our efforts to fulfill the philosophy decreed by the Hawaii State motto, ‘Ua mau ke ea o ka aina i ka pono [The life of the land is perpetuated in righteousness].’” Haw. Const. pmbl. (The first known expression of our state motto came from King Kamehameha III’s address on Lā Hoʻihoʻi Ea, or Restoration Day, after political power was restored to the Kingdom of Hawaiʻi following an unlawful British occupation. See 2022 Haw. Sess. Laws Act 82, § 1 at 188-89.). The Hawaiʻi Constitution is respectful to all faiths and philosophies. Our state’s religious diversity and inclusivity, the delegates appreciated, differed from the Christian-dominated context in other parts of the country. To avoid governmental endorsement and support of any faith, the Preamble reads “Divine Guidance” – not a specific deity. First, “[n]o grant shall be made in violation of Section 4 of Article I of this constitution.” Haw. Const. art. VII, § 4. Second, the public school system shall be “free from sectarian control” and public funds shall not be appropriated to support or benefit “any sectarian or nonsectarian private educational institution.” Haw. Const. art. X, § 1. Reinforced by generations of jurisprudence, the wall stands for the principle that government neither advances nor inhibits religion. Besides Everson and McCollum, other mid-20th century opinions shared the 18th century vision that government involvement in religion undermines the secular character of civil society.
September 21, 2025 at 1:53 AM
epsteinweb.bsky.social
Parts 1-4/6 — EFTA01140247.jpg
#epsteinweb #efta01140247
https://epsteinweb.org
Available in the iOS app store now!
https://apps.apple.com/us/app/epstein-web/id6758880661
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May 10, 2026 at 3:37 PM
seennfl.bsky.social
Xavier Johnson leads FCS with 472 receiving yards. The top five are separated by 58 yards.
Receiving Yards, top 5 for FCS. 1. Xavier Johnson 472. 2. Samuel Gbatu Jr. 468. 3. Brooks Davis 446. 4. Kory Jones 419. 5. Marquis Willis 414.
September 22, 2026 at 10:24 PM