#LD50-Test
Jeff gonna test the LD50 of schadenfreude.
May 30, 2024 at 9:56 PM
LD50 is the lethal dose of 50% of test animals exposed to a substance.

The LD50 of the Inland Taipan is 0.025mg/kg.

For comparison, cyanide has an LD50 of 4mg/kg.
Bad news: He probably won't survive this unless one of the zoos with access to the antivenom offers him some and at least one outright refused because it's precious and he's... that.

Good news: Surviving this without antivenom is so rare he'll force the wikipedia to update if he makes it. 🤷🏾‍♂️
there's currently massive unrest in the venomous snake hobbyist community bc some dumbfuck who owned an inland taipan in the US, encouraged free handling and didn't have anti-venom (insane) got bit and now he's in the hospital on a ventilator and also he posted this one (1) week ago
September 7, 2024 at 5:34 PM
For everyone in the back, the LD50 is the Lethal Dose in 50% of (animal) test subjects.

Cannabis is not poison lol not even close
Poison? Well, all things can be poison but the dose makes the poison…

The estimated (bc it isn’t something that has ever happened) LD50 for THC is 4-15 grams!

That means an adult would need to take ~800-3000 standard (and this is the higher end of standard dosing) edibles at once to be a concern.
'This is a poison': Texas Senate passes bill that would ban THC products from being sold
April 11, 2025 at 3:39 AM
Über 160.000 Mäuse sterben jedes Jahr in der EU für Botox-Tests. Doch jetzt kommt Bewegung in das Thema: Der grausame LD50-Test könnte zum Glück schon bald der Vergangenheit angehören. Jetzt lesen! 🐭✨

soundsvegan.com/2026/08/boto...

#vegan #crueltyfree #tierschutz #botox #tierversuche #SoundsVegan
Botox ohne Mäuseleid: Das Ende des LD50-Tests
Uber 160.000 Mäuse sterben jährlich in der EU fuer Botox-Tests. Die EDQM plant die Abschaffung des LD50-Tests. Jetzt Fakten und Hintergründe holen!
soundsvegan.com
August 19, 2026 at 1:17 PM
You’d better not try an LD50 test on him
June 25, 2025 at 7:49 PM
Well obviously you can’t do an LD50 test on an individual! 😈
June 25, 2025 at 7:50 PM
The censors wouldn't let it run one minute longer because that was the LD50/50 for the test audience.
September 21, 2025 at 1:47 AM
🎉 Cruelty Free International welcomes the European Directorate for the Quality of Medicines and Healthcare's commitment to phase out the mouse lethal dose 50 (LD50) test for Botox products.

#AnimalWelfare #GoodNews
September 9, 2026 at 2:26 PM
A delicious spice, but you can also raise entries by quoting its LD50 value (dose that kills 50% of test animals)
November 28, 2024 at 11:00 PM
One last fact - "Most venomous" is based on the LD50 test which finds the minimal dosage to kill 50% of envenomated mice. Specialist rodent feeders score high on this test.
December 9, 2024 at 9:51 PM
Lethality should (but doesn't) play a part in whether something is dangerous enough to even be listed at all. Lethal dose (LD50) is the amount of an ingested substance that kills 50% of a test sample.

Aspirin : 1500 mg/kg body weight
Cannabis : They estimate you'd need to ingest 1,500lbs in 15mins
February 1, 2024 at 7:18 PM
View the full report here 👉 irishantivivisection.org/statistics/

How you can help: The Irish Anti-Vivisection Society calls on the Irish Government to enact legislation immediately to ban the LD50 Botulinum Toxin Potency Test for cosmetic procedures.

✍️ my.uplift.ie/petitions/st...
Statistics - Irish Anti-Vivisection Society
The Irish government’s HPRA has just released its statistics report for animal experiments in Ireland for the year 2022.
irishantivivisection.org
January 27, 2026 at 12:09 PM
You’re proposing an alternative universe where we run an extended test on both the ballistic and adhesive properties of excrement, and on the LD50 of schadenfruede?

That’s bold.
November 4, 2024 at 10:44 PM
according to Pfizer the ld50 of oral estradiol varies depending on what I assume is different pill medium but is at least 2000-10000mg/kg in rats

“at least” because “the toxicity endpoint being tested was not achievable at the highest dose used in the test”
July 21, 2025 at 11:43 PM
Über 200.000 Mäuse sterben jährlich in #Europa für #Botox-Tests – trotz #tierversuchsfreier Testmethoden! Der grausame #LD50-Test wird weiter eingesetzt. Wir fordern: Schluss mit #Tierleid – tierversuchsfreie Methoden müssen #europaweit verpflichtend werden!
August 6, 2025 at 10:35 AM
Learned today that they use animal testing on every batch of botox before using it on humans.

”Each batch of botox is tested using what is known as the LD50 test. That involves injecting a sample of botox, which is the brand name for the nerve poison botulinum toxin A, into the abdomen of mice.
February 22, 2025 at 3:50 PM
The lethal dose which kills 50% of the test subjects given it. eg the LD50 for table salt (in humans) is approximately 3.75g/kg of body weight.
October 27, 2025 at 10:53 PM
The Irish Anti-Vivisection Society calls on the Irish Government to enact legislation immediately to ban the LD50 Botulinum Toxin Potency Test for cosmetic procedures.

my.uplift.ie/petitions/st...
February 15, 2026 at 10:57 AM
Not exclusively. A measure of toxicity is the LD50 (lethal dose to kill 50% of the test population). Apparently, it takes less salt to kill vs glyphosate.

Note that this is ONLY lethality. Which I question as a measure of safety since a compound can wreak havoc on your body before it kills you 🤪
October 1, 2025 at 5:33 PM