VK can change what the Russian Max messenger does to you, one user at a time. Its surveillance features can be switched on without you noticing. Read our full analysis.

Lois Lowry’s The Giver is the quintessential dystopian novel, followed by its remarkable companions, Gathering Blue, Messenger, and Son.Jonas's world is perfect. Everything is under control. There is ...

Das Softwareunternehmen Photon hat am 2. Oktober 2026 eine Seed-Finanzierungsrunde über 4,5 Millionen US-Dollar abgeschlossen. Die Runde wurde von den Wagniskapitalgebern Gradient und A* angeführt. Zudem beteiligten sich Vercel, HongShan, Z Fellows, Llama Ventures, Karman sowie mehrere Angel-Investoren an dem Infrastrukturanbieter für mobile Kommunikationskanäle. Schnittstelle für Konversationen über etablierte Messenger Photon entwickelt technische Infrastruktur, um […] The post Photon: Messaging-Infrastruktur für KI-Agenten erhält 4,5 Millionen Dollar appeared first on BornCity.

To assess CMA activity during senescence in aging cells, we isolated mouse ear fibroblasts (mEFs), a reliable primary cell model for the study of aging in vitro39,40, as, at early passages, they allow analyzing aging separately from replicative senescence. We confirmed, as reported previously39, that mEFs from aged mice (23-month-old; 23 m) were not more senescent than those from young mice (4-month-old; 4 m) using senescence-associated β-galactosidase (SA-β-gal) staining or p16INK4A messenger RNA, but could still be induced into senescence 7 days after initial treatment with palbociclib (Palbo) (Extended Data Fig. 1a,b). ProteoSTAT staining confirmed the characteristic loss of proteostasis and increased protein aggregation in aged mEFs (Extended Data Fig. 1c), which could be directly attributed to the CMA decline with age29, as we found comparable protein aggregation in mEFs from 4 m CMA-deficient (L2AKO) mice32 (Extended Data Fig. 1c). To monitor CMA activity upon senescence induction, we used mEFs from transgenic KFERQDendra mice, which systemically express a fluorescent CMA reporter41,42 consisting of the CMA-targeting motif KFERQ fused to Dendra2. KFERQDendra is recognized by Hsc70 and delivered to LAMP2A, generating fluorescent lysosomal puncta42. Following LAMP2A binding and unfolding, KFERQDendra is translocated for degradation in the lysosomal lumen42. The number of...