#Metaflammation
Really glad we pulled this of together! @wachtenlab.bsky.social, Andreas Schlitzer and all PIs from #Metaflammation
After the celebrations of making it into the second funding period, we are now ready for a fresh start in this community - stay tuned for more information about #metaflammation #obesity from our @sfb1454.bsky.social funded by the @dfgpublic.bsky.social
www.sfb1454-metaflammation.de
December 5, 2024 at 1:04 PM
Kicking off the 2nd funding period of our SFB1454 on #metaflammation ! Lots of great discussions and visiting our #healthybition at the #museumkoenig in Bonn! Go and visit the exhibition until end of October 2025!
January 30, 2025 at 8:27 PM
After the celebrations of making it into the second funding period, we are now ready for a fresh start in this community - stay tuned for more information about #metaflammation #obesity from our @sfb1454.bsky.social funded by the @dfgpublic.bsky.social
www.sfb1454-metaflammation.de
December 5, 2024 at 12:51 PM
Great to see research from our SFB featured at the Bardet-Biedl Syndrome Patient Days 2024! Fantastic discussions and engagement! #BBS #cilia #metaflammation
Fantastic discussions and interactions at the Bardet-Biedl Syndrome Patient Days 2024 — huge thanks to Helen for organizing such a meaningful event! #cilia #BBS @wachtenlab.bsky.social
May 25, 2025 at 2:13 PM
New collaborative effort from our #metaflammation SFB1454 PIs headed by @masslab.bsky.social
1/ 🚨 New preprint alert! 🚨
Micro- and nanoplastics (MNPs) are everywhere, but what happens when they get inside us? Our latest study reveals how chronic plastic exposure affects macrophages and metabolism in a size-dependent manner. 🧵👇 www.researchsquare.com/article/rs-6...
Size-dependent plastic exposure disrupts macrophage function and tissue-specific metabolism
Plastic pollution is an emerging yet understudied environmental risk to the immune system. Once ingested, nano- and microplastic particles (MNPs) can translocate from the gut to internal organs, with ...
www.researchsquare.com
March 19, 2025 at 7:57 AM
🔬 Neuer Forschungsschwerpunkt an der #MedUniWien:

Das neu eröffnete Christian Doppler Labor für #Metaflammation in der #Peritonealdialyse erforscht neue Therapieansätze bei chronischem #Nierenversagen – zur Verbesserung von Lebensqualität und Lebenserwartung von Patient:innen. ⬇️
CD-Labor für Metaflammation in der Peritonealdialyse eröffnet
Weitere Details erfahren!
www.meduniwien.ac.at
May 21, 2026 at 7:05 AM
SFB 1454 #Metaflammation on air 📻: Im Deutschlandfunk erläutern führende Wissenschaftler wie Waldemar Kolanus & Christoph Wilhelm wie #Ernährung, #Fasten und #Stoffwechselprozesse die #Immunantwort beeinflussen.
🎧 Hier anhören: lnkd.in/emkKSiQN; @unibonn.bsky.social
May 7, 2026 at 6:49 AM
Chronic low-grade metabolic #inflammation drives insulin resistance and metabolic dysfunction in #obesity. Yun Sok Lee highlights the lesser known beneficial effects of this inflammation and how they can transition into detrimental outcomes. 🧪
Immunometabolism in obesity: Understanding the beneficial and detrimental roles of inflammation
Chronic low-grade metabolic inflammation (known as metaflammation) drives insulin resistance and metabolic dysfunction in obesity. This Essay discusses the immunometabolic mechanisms underlying…
plos.io
January 22, 2026 at 5:25 PM
Chronic low-grade metabolic #inflammation drives insulin resistance and metabolic dysfunction in #obesity. Yun Sok Lee highlights the lesser known beneficial effects of this inflammation and how they can transition into detrimental outcomes. 🧪
Immunometabolism in obesity: Understanding the beneficial and detrimental roles of inflammation
Chronic low-grade metabolic inflammation (known as metaflammation) drives insulin resistance and metabolic dysfunction in obesity. This Essay discusses the immunometabolic mechanisms underlying…
plos.io
January 23, 2026 at 9:00 AM
Am I reading well that endocannabinoids are anti-inflammatory?
"Endocannabinoid stimulation shifts activated macrophage outputs away from pro-inflammatory cytokines (Il1b, Ccl2) toward extracellular matrix (ECM) proteoglycan remodeling and intercellular signaling."

www.biorxiv.org/content/10.6...
Metabolomics identifies endocannabinoid system remodeling during obesity associated inflammation in adipose tissue
Visceral white adipose tissue (vAT) is more susceptible than subcutaneous white adipose tissue (scAT) to obesity-associated metaflammation, but the metabolic pathways accompanying this depot specific ...
www.biorxiv.org
September 28, 2026 at 8:47 AM
What defines the #WesternLifestyle and how does it impact our health and the planet? 🌍
“What the Health – Eine Welt. Deine Gesundheit!” explores these connections!
Visit our #healthybition and the accompanying program
📍 @museumkoenig until 26.10.2025
#unibonn #metaflammation #unistiftung
December 11, 2024 at 7:33 AM
Check out this great collaboration project from our #metaflammation SFB members!
We are thrilled to present our new story on #neonatal #liver #macrophages and how they crosstalk with #hepatocytes during this early stage of life
👇
Kupffer cells control neonatal hepatic metabolism via Igf1 signaling https://www.biorxiv.org/content/10.1101/2025.02.19.638983v1
March 12, 2025 at 10:24 AM
Das klingt super.
Ich bin seit dem 6.12.25 dabei. Muss aber nur 8 kg runterbekommen. 4,5 kg sind geschafft🥳

Weniger Fett = weniger Entzündungen, ich hoffe sehr darauf 🤞🏻

www.internisten-im-netz.de/aktuelle-mel...
Stoffwechselbedingte Entzündung durch Übergewicht gefährdet die Gesundheit: Internisten im Netz
Fettzellen setzen insbesondere im Bauchbereich Mediatoren und Hormone frei, die eine Entzündung hervorrufen. Diese Metaflammation erhöht langfristig…
www.internisten-im-netz.de
January 17, 2026 at 10:24 AM
Chronic low-grade metabolic #inflammation drives insulin resistance and metabolic dysfunction in #obesity. Yun Sok Lee highlights the lesser known beneficial effects of this inflammation and how they can transition into detrimental outcomes. 🧪
Immunometabolism in obesity: Understanding the beneficial and detrimental roles of inflammation
Chronic low-grade metabolic inflammation (known as metaflammation) drives insulin resistance and metabolic dysfunction in obesity. This Essay discusses the immunometabolic mechanisms underlying…
plos.io
January 22, 2026 at 1:50 PM
TU Braunschweig provides important building blocks for inflammation research
The German Research Foundation (DFG) has approved the Collaborative Research Centre (CRC) 1454 “Metaflammation and Cellular Programming” for a second funding period...
weiterlesen
November 29, 2024 at 11:38 AM
TU Braunschweig liefert wichtige Bausteine für Entzündungsforschung
Die Deutsche Forschungsgemeinschaft (DFG) hat den Sonderforschungsbereich (SFB) „Metaflammation“ in eine zweite Förderperiode aufgenommen. Im Zentrum des Forschungsverbun...
weiterlesen
November 29, 2024 at 11:33 AM
*Job Opportunity*

Prof. Sven Burgdorf is seeking a Postdoc in Cellular Immunology and Metabolism as part of our SFB!

If you are passionate about #CellularImmunology and #Metaflammation find out more here:

www.uni-bonn.de/de/universit...
Postdoc in cellular immunology and metabolism
Full time, temporary, EG 13, Reference number: 3.3/2025/13
www.uni-bonn.de
March 10, 2025 at 1:20 PM
“ it is likely that #metaflammation is not inherently pathological, but rather its impact on metabolic health is dependent upon contextual determinants, the acuity versus chronicity of the inflammatory response, & the specific constituents of the inflammatory milieu.” This was proposed in 2003. 🙄2/2
January 22, 2026 at 2:06 PM
Exploring Metaflammation with Dr. James LaValle: Insights into Health, Nutrition, and Longevity youtu.be/b4pMi0JMHU8?...
Metaflammaging with Dr. James LaValle: Rational Wellness Podcast 388
YouTube video by Ben Weitz, DC
youtu.be
November 29, 2024 at 4:04 PM
In his Essay, Yun Sok Lee investigates the process of metaflammation, the chronic low-grade inflammatory response that occurs in metabolic diseases such as obesity and type 2 diabetes, exploring how systemic changes in #metabolism can affect tissue-resident immune cells plos.io/4sOCOqh
Immunometabolism in obesity: Understanding the beneficial and detrimental roles of inflammation
Chronic low-grade metabolic inflammation (known as metaflammation) drives insulin resistance and metabolic dysfunction in obesity. This Essay discusses the immunometabolic mechanisms underlying metafl...
plos.io
February 3, 2026 at 10:36 AM