MitoCatch is a cell-type-specific mitochondrion-targeting system that links mitochondria and the cell surface by protein binders and delivers mitochondria into the target cell.

Scientists created MitoCatch, a method to send healthy mitochondria directly to specific damaged cells. This is important because mitochondrial issues are linked to diseases like Parkinson’s, Alzheimer’s, and heart failure, and current approaches can’t target the right cells well. In tests, the delivered mitochondria worked normally inside cells and improved survival of damaged neurons and eye cells without triggering immune reactions. It’s an early but promising step toward more precise treatments that fix cell energy problems at the source.

MitoCatch is a cell-type-specific mitochondrion-targeting system that links mitochondria and the cell surface by protein binders and delivers mitochondria into the target cell.

MitoCatch is a cell-type-specific mitochondrion-targeting system that links mitochondria and the cell surface by protein binders and delivers mitochondria into the target cell.

MitoCatch is a cell-type-specific mitochondrion-targeting system that links mitochondria and the cell surface by protein binders and delivers mitochondria into the target cell.

MitoCatch is a cell-type-specific mitochondrion-targeting system that links mitochondria and the cell surface by protein binders and delivers mitochondria into the target cell.

MitoCatch is a cell-type-specific mitochondrion-targeting system that links mitochondria and the cell surface by protein binders and delivers mitochondria into the target cell.

MitoCatch is a cell-type-specific mitochondrion-targeting system that links mitochondria and the cell surface by protein binders and delivers mitochondria into the target cell.

MitoCatch is a cell-type-specific mitochondrion-targeting system that links mitochondria and the cell surface by protein binders and delivers mitochondria into the target cell.

Nature Reviews Molecular Cell Biology, Published online: 09 June 2026; doi:10.1038/s41580-026-00986-wIn this Tools of the Trade article, Ayupov (Roska lab) describes the development of MitoCatch, a method to display protein binders on the mitochondrial surface to facilitate cell-type-specific targeting during mitochondrial transplantation.

Nature Reviews Molecular Cell Biology, Published online: 09 June 2026; doi:10.1038/s41580-026-00986-wIn this Tools of the Trade article, Ayupov (Roska lab) describes the development of MitoCatch, a method to display protein binders on the mitochondrial surface to facilitate cell-type-specific targeting during mitochondrial transplantation.

MitoCatch is a cell-type-specific mitochondrion-targeting system that links mitochondria and the cell surface by protein binders and delivers mitochondria into the target cell.

MitoCatch resuelve uno de los grandes retos del trasplante mitocondrial: dirigir estas estructuras energéticas a tipos celulares concretos. El estudio, liderado por la española Verónica Moreno, muestr...

MitoCatch resuelve uno de los grandes retos del trasplante mitocondrial: dirigir estas estructuras energéticas a tipos celulares concretos. El estudio, liderado por la española Verónica Moreno, muestr...

Scientists led by Botond Roska at the Institute of Molecular and Clinical Ophthalmology Basel (IOB) have developed MitoCatch, a system that enables targeted delivery of healthy mitochondria to specific cell types affected by disease. This innovation is a major step toward precision mitochondrial therapy.

MitoCatch is a cell-type-specific mitochondrion-targeting system that links mitochondria and the cell surface by protein binders and delivers mitochondria into the target cell.

MitoCatch is a cell-type-specific mitochondrion-targeting system that links mitochondria and the cell surface by protein binders and delivers mitochondria into the target cell.