Great pleasure to have worked on this! Design peptides, miniproteins, megaproteins, nanobodies, ScFvs, anything you want all under one roof of BindCraft2. And it's easier, faster, and better than ever! Includes multitargeting against multiple different proteins as well.
ʙɪɴᴅᴄʀᴀꜰᴛ2 is out, and we're not waiting for the paper. The full code drops today, free for academic and industry use.
We're releasing it early so you can start designing right now, and bring its full power to the current Adaptyv competition.
github.com/PacesaLab/Bi...
We're releasing it early so you can start designing right now, and bring its full power to the current Adaptyv competition.
github.com/PacesaLab/Bi...
September 21, 2026 at 10:06 AM
Great pleasure to have worked on this! Design peptides, miniproteins, megaproteins, nanobodies, ScFvs, anything you want all under one roof of BindCraft2. And it's easier, faster, and better than ever! Includes multitargeting against multiple different proteins as well.
Natural Coumarin-Hybridized Thiazolylbenzonitriles as New Structural Scaffolds to Exert Potentially Multitargeting Supramolecular Antibacterial Behavior
doi.org/10.1002/cjoc...
doi.org/10.1002/cjoc...
May 23, 2025 at 11:24 PM
Natural Coumarin-Hybridized Thiazolylbenzonitriles as New Structural Scaffolds to Exert Potentially Multitargeting Supramolecular Antibacterial Behavior
doi.org/10.1002/cjoc...
doi.org/10.1002/cjoc...
@cp-trendspharma.bsky.social Multitargeting neuroimmune pathways: novel candidates for chronic pain relief
www.cell.com/trends/pharm...
www.cell.com/trends/pharm...
September 4, 2025 at 4:05 AM
@cp-trendspharma.bsky.social Multitargeting neuroimmune pathways: novel candidates for chronic pain relief
www.cell.com/trends/pharm...
www.cell.com/trends/pharm...
Boomerangs. I really only use dragons in boss fights, so swords kind of become less useful than multitargeting in rando battles.
May 21, 2026 at 3:38 PM
Boomerangs. I really only use dragons in boss fights, so swords kind of become less useful than multitargeting in rando battles.
oomf helped me get through subterra sanctum i actually liked that even if i dislike multitargeting in this game (and eternal bloom)
February 24, 2026 at 2:56 AM
oomf helped me get through subterra sanctum i actually liked that even if i dislike multitargeting in this game (and eternal bloom)
any chance it has multitargeting capabilities
August 10, 2026 at 6:02 AM
any chance it has multitargeting capabilities
Clickable Multitargeting Cross-Linkers Based on SuFEx for In Vivo Cross-Linking Mass Spectrometry pubs.acs.org/doi/10....
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#proteomics #prot-paper
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#proteomics #prot-paper
December 23, 2025 at 1:40 PM
Clickable Multitargeting Cross-Linkers Based on SuFEx for In Vivo Cross-Linking Mass Spectrometry pubs.acs.org/doi/10....
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#proteomics #prot-paper
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#proteomics #prot-paper
Multitargeting neuroimmune pathways: novel candidates for chronic pain relief
Multitargeting neuroimmune pathways: novel candidates for chronic pain relief
Chronic pain remains inadequately managed, partly because of insufficient consideration of neuroimmune interactions in therapeutic design and a continued reliance on single-target strategies ill-suited to its complexity. Multitarget-directed ligands that modulate the non-neuronal microenvironment of neuronal pain pathways show promise, supported by encouraging preclinical data and initial clinical findings.
dlvr.it
September 4, 2025 at 11:42 AM
Multitargeting neuroimmune pathways: novel candidates for chronic pain relief
I'm playing on Hard mode, but only like Lv. 5. I've heard the difficulty spikes at a certain point and I'm excited for that, it's crazy how many tools I have already (three different ways of multitargeting)
November 16, 2024 at 2:34 PM
I'm playing on Hard mode, but only like Lv. 5. I've heard the difficulty spikes at a certain point and I'm excited for that, it's crazy how many tools I have already (three different ways of multitargeting)
Curious paper!
„Accessory microRNA byproducts expand RNA interference via microprocessor-mediated cleavage activation“
I was thinking offset reads first, but this does not look like it? Thoughts?
www.science.org/doi/10.1126/...
„Accessory microRNA byproducts expand RNA interference via microprocessor-mediated cleavage activation“
I was thinking offset reads first, but this does not look like it? Thoughts?
www.science.org/doi/10.1126/...
Accessory microRNA byproducts expand RNA interference via microprocessor-mediated cleavage activation
Insights into microRNA processing guide the design of an RNA medicine strategy that enables precise multitargeting against cancer.
www.science.org
March 2, 2026 at 10:24 PM
Curious paper!
„Accessory microRNA byproducts expand RNA interference via microprocessor-mediated cleavage activation“
I was thinking offset reads first, but this does not look like it? Thoughts?
www.science.org/doi/10.1126/...
„Accessory microRNA byproducts expand RNA interference via microprocessor-mediated cleavage activation“
I was thinking offset reads first, but this does not look like it? Thoughts?
www.science.org/doi/10.1126/...
And finally, please join us in congratulating this year’s RSC Emerging Technologies competition Health category winner University of Liverpool for their work on Synthetic teixobactins: multitargeting antibiotics to combat resistant superbugs.
#ChemSky #RSCEmergingTech #technology #health
#ChemSky #RSCEmergingTech #technology #health
July 8, 2025 at 10:00 AM
And finally, please join us in congratulating this year’s RSC Emerging Technologies competition Health category winner University of Liverpool for their work on Synthetic teixobactins: multitargeting antibiotics to combat resistant superbugs.
#ChemSky #RSCEmergingTech #technology #health
#ChemSky #RSCEmergingTech #technology #health
They first discuss penicillin and its derivatives that interfere with production of the bacterial peptidoglycan cell wall. They note a key feature: it targets a protein is is "both essential and highly conserved. Penicillin is the first example of this multitargeting paradigm." 3/n
September 22, 2024 at 1:51 PM
They first discuss penicillin and its derivatives that interfere with production of the bacterial peptidoglycan cell wall. They note a key feature: it targets a protein is is "both essential and highly conserved. Penicillin is the first example of this multitargeting paradigm." 3/n
../.. tener algún tipo de enfermedad o condición endocrino-metabólica donde esos ejes no estén alterados 😅
Ello sin entrar en la parte SNC.
En otras palabras, en endocrino-metabólico y cardiovascular los resultados superan expectativas por efecto multitargeting no (tan) pronosticado.
Ello sin entrar en la parte SNC.
En otras palabras, en endocrino-metabólico y cardiovascular los resultados superan expectativas por efecto multitargeting no (tan) pronosticado.
July 29, 2026 at 4:26 PM
../.. tener algún tipo de enfermedad o condición endocrino-metabólica donde esos ejes no estén alterados 😅
Ello sin entrar en la parte SNC.
En otras palabras, en endocrino-metabólico y cardiovascular los resultados superan expectativas por efecto multitargeting no (tan) pronosticado.
Ello sin entrar en la parte SNC.
En otras palabras, en endocrino-metabólico y cardiovascular los resultados superan expectativas por efecto multitargeting no (tan) pronosticado.
Discovery of benzopyronyl imidazolidinediones as new structural skeleton of potential multitargeting antibacterial agents
Discovery of benzopyronyl imidazolidinediones as new structural skeleton of potential multitargeting antibacterial agents - PubMed
This work developed a class of unique benzopyronyl imidazolidinediones (BIs) as new structural skeleton of potential multitargeting antibacterial agents to confront dreadful Staphylococcus aureus infections....
t.co
September 16, 2025 at 11:05 AM
Discovery of benzopyronyl imidazolidinediones as new structural skeleton of potential multitargeting antibacterial agents
Clickable Multitargeting Cross-Linkers Based on SuFEx for In Vivo Cross-Linking Mass Spectrometry #AC pubs.acs.org/doi/10.1021/...
Clickable Multitargeting Cross-Linkers Based on SuFEx for In Vivo Cross-Linking Mass Spectrometry
Cross-linking mass spectrometry (XL-MS) is a powerful technique to study protein structures and protein–protein interactions. The coverage of amino acids determines the depth of the XL-MS analysis and...
pubs.acs.org
December 23, 2025 at 1:35 PM
Clickable Multitargeting Cross-Linkers Based on SuFEx for In Vivo Cross-Linking Mass Spectrometry #AC pubs.acs.org/doi/10.1021/...
⚡ Dein #dotnetMAUI-Boost!
Hol dir das kostenlose #CheatSheet von Dr. Veikko Krypczyk – kompakt & superpraktisch für #UI, Architektur, #MultiTargeting & mehr.
💡Zum Dowload: https://basta.net/cheat-sheet-dotnet-maui/?loc=ffm&utm_source=bluesky&utm_medium=social&utm_campaign=content-basta
#bastacon
Hol dir das kostenlose #CheatSheet von Dr. Veikko Krypczyk – kompakt & superpraktisch für #UI, Architektur, #MultiTargeting & mehr.
💡Zum Dowload: https://basta.net/cheat-sheet-dotnet-maui/?loc=ffm&utm_source=bluesky&utm_medium=social&utm_campaign=content-basta
#bastacon
December 3, 2025 at 10:02 AM
⚡ Dein #dotnetMAUI-Boost!
Hol dir das kostenlose #CheatSheet von Dr. Veikko Krypczyk – kompakt & superpraktisch für #UI, Architektur, #MultiTargeting & mehr.
💡Zum Dowload: https://basta.net/cheat-sheet-dotnet-maui/?loc=ffm&utm_source=bluesky&utm_medium=social&utm_campaign=content-basta
#bastacon
Hol dir das kostenlose #CheatSheet von Dr. Veikko Krypczyk – kompakt & superpraktisch für #UI, Architektur, #MultiTargeting & mehr.
💡Zum Dowload: https://basta.net/cheat-sheet-dotnet-maui/?loc=ffm&utm_source=bluesky&utm_medium=social&utm_campaign=content-basta
#bastacon
No multitargeting in Visual C++ 2010 http://social.msdn.microsoft.com/Forums/en-US/vcprerelease/thread/9b08cc5e-933e-4916-8c3c-8c3cbf9beaf5/
November 21, 2024 at 5:27 PM
No multitargeting in Visual C++ 2010 http://social.msdn.microsoft.com/Forums/en-US/vcprerelease/thread/9b08cc5e-933e-4916-8c3c-8c3cbf9beaf5/
BriaCell’s Subsidiary, BriaPro, Files Patent Application for Immuno-Oncology Platform with Novel Multitargeting Agents - GlobeNewswire: BriaCell’s Subsidiary, BriaPro, Files Patent Application for Immuno-Oncology Platform with Novel Multitargeting Agents GlobeNewswire
BriaCell’s Subsidiary, BriaPro, Files Patent Application for Immuno-Oncology Platform with Novel Multitargeting Agents - GlobeNewswire
BriaCell’s Subsidiary, BriaPro, Files Patent Application for Immuno-Oncology Platform with Novel Multitargeting Agents GlobeNewswire
news.google.com
July 29, 2025 at 11:35 AM
BriaCell’s Subsidiary, BriaPro, Files Patent Application for Immuno-Oncology Platform with Novel Multitargeting Agents - GlobeNewswire: BriaCell’s Subsidiary, BriaPro, Files Patent Application for Immuno-Oncology Platform with Novel Multitargeting Agents GlobeNewswire
💡CBD+ Active Cream - Multi-target Anti-aging
7 scientific mechanisms in one cream!
#OptoDerm #CBDActiveCream #CBDSkincare #SkinTransformation #AntiInflammatory #SensitiveSkin #SkincareScience #SkinCalming #SkinHealth #Antiaging #MultiTargeting #OxidativeStress #BarrierFunction #Collagen
7 scientific mechanisms in one cream!
#OptoDerm #CBDActiveCream #CBDSkincare #SkinTransformation #AntiInflammatory #SensitiveSkin #SkincareScience #SkinCalming #SkinHealth #Antiaging #MultiTargeting #OxidativeStress #BarrierFunction #Collagen
November 4, 2025 at 10:00 AM
💡CBD+ Active Cream - Multi-target Anti-aging
7 scientific mechanisms in one cream!
#OptoDerm #CBDActiveCream #CBDSkincare #SkinTransformation #AntiInflammatory #SensitiveSkin #SkincareScience #SkinCalming #SkinHealth #Antiaging #MultiTargeting #OxidativeStress #BarrierFunction #Collagen
7 scientific mechanisms in one cream!
#OptoDerm #CBDActiveCream #CBDSkincare #SkinTransformation #AntiInflammatory #SensitiveSkin #SkincareScience #SkinCalming #SkinHealth #Antiaging #MultiTargeting #OxidativeStress #BarrierFunction #Collagen
Head Explody: still the best super power.
The winner and all time champion: unlimited range head explody by category.
First runner up: field of view multitargeting line of sight head explody.
Miss Congeniality: head explody when you see the whites of their eyes.
The winner and all time champion: unlimited range head explody by category.
First runner up: field of view multitargeting line of sight head explody.
Miss Congeniality: head explody when you see the whites of their eyes.
January 21, 2025 at 8:36 PM
Head Explody: still the best super power.
The winner and all time champion: unlimited range head explody by category.
First runner up: field of view multitargeting line of sight head explody.
Miss Congeniality: head explody when you see the whites of their eyes.
The winner and all time champion: unlimited range head explody by category.
First runner up: field of view multitargeting line of sight head explody.
Miss Congeniality: head explody when you see the whites of their eyes.
Visual Studio 2019 for Mac version 8.3 with support for .NET Core 3.0, Android 10, iOS 13, MultiTargeting, XAML Hot Reload, etc.
devblogs.microsoft.com/visualstudio/v…
devblogs.microsoft.com/visualstudio/v…
November 27, 2024 at 12:53 PM
Visual Studio 2019 for Mac version 8.3 with support for .NET Core 3.0, Android 10, iOS 13, MultiTargeting, XAML Hot Reload, etc.
devblogs.microsoft.com/visualstudio/v…
devblogs.microsoft.com/visualstudio/v…
#BCTX #BCTXW #BCTXZ BriaCell’s Subsidiary, BriaPro, Files Patent Application for Immuno-Oncology Platform with Novel Multitargeting Agents
https://www.stocktitan.net/news/BCTX/bria-cell-s-subsidiary-bria-pro-files-patent-application-for-immuno-f92cgu0wpnyl.html
https://www.stocktitan.net/news/BCTX/bria-cell-s-subsidiary-bria-pro-files-patent-application-for-immuno-f92cgu0wpnyl.html
Revolutionary Cancer Treatment: BriaCell's New Platform Targets 5 Major Cancer Types Simultaneously
Novel TILsRx platform enables targeted treatment of multiple cancers including prostate, lung, and breast. Discover how this breakthrough technology transforms immunotherapy. Learn more.
www.stocktitan.net
July 29, 2025 at 11:30 AM
#BCTX #BCTXW #BCTXZ BriaCell’s Subsidiary, BriaPro, Files Patent Application for Immuno-Oncology Platform with Novel Multitargeting Agents
https://www.stocktitan.net/news/BCTX/bria-cell-s-subsidiary-bria-pro-files-patent-application-for-immuno-f92cgu0wpnyl.html
https://www.stocktitan.net/news/BCTX/bria-cell-s-subsidiary-bria-pro-files-patent-application-for-immuno-f92cgu0wpnyl.html
We're still far from treating #Parkinson #dementia with #DBS, yet our trial indicates that:
- multitargeting is possible (GPi+Nucleus Basalis of Meynert): we're moving away from targets and focusing on trajectories
- GPi DBS is feasible in frail patients excluded in the past
- multitargeting is possible (GPi+Nucleus Basalis of Meynert): we're moving away from targets and focusing on trajectories
- GPi DBS is feasible in frail patients excluded in the past
November 23, 2024 at 7:07 PM
We're still far from treating #Parkinson #dementia with #DBS, yet our trial indicates that:
- multitargeting is possible (GPi+Nucleus Basalis of Meynert): we're moving away from targets and focusing on trajectories
- GPi DBS is feasible in frail patients excluded in the past
- multitargeting is possible (GPi+Nucleus Basalis of Meynert): we're moving away from targets and focusing on trajectories
- GPi DBS is feasible in frail patients excluded in the past
jesus; all it took was clearing everything out of bin; removing alpine; purging dotnet from the system because ubuntu was on 9.0.108 which was before multitargeting was enabled, hitting repeatedly with a rock and it finally works.
July 23, 2025 at 4:42 PM
jesus; all it took was clearing everything out of bin; removing alpine; purging dotnet from the system because ubuntu was on 9.0.108 which was before multitargeting was enabled, hitting repeatedly with a rock and it finally works.