THIS IS HUGE! Researchers at the University of Illinois have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections (MORE THAN 130 multidrug-resistant bacterial strains, in fact) while sparing the gut microbiome!
Let’s talk about that! 🧪🧵⬇️
Let’s talk about that! 🧪🧵⬇️
June 11, 2024 at 4:00 PM
THIS IS HUGE! Researchers at the University of Illinois have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections (MORE THAN 130 multidrug-resistant bacterial strains, in fact) while sparing the gut microbiome!
Let’s talk about that! 🧪🧵⬇️
Let’s talk about that! 🧪🧵⬇️
mRNA vaccines for multidrug-resistant bacteria: promise, challenges, and microbiome-informed strategies - The Lancet Microbe www.thelancet.com/journals/lan...
mRNA vaccines for multidrug-resistant bacteria: promise, challenges, and microbiome-informed strategies
Antimicrobial resistance (AMR) has made multidrug-resistant organisms (MDROs), particularly
ESKAPE-E pathogens (including Enterococcus faecium, Staphylococcus aureus, Klebsiella
pneumoniae, Acinetobac...
www.thelancet.com
July 27, 2026 at 2:43 PM
mRNA vaccines for multidrug-resistant bacteria: promise, challenges, and microbiome-informed strategies - The Lancet Microbe www.thelancet.com/journals/lan...
💊 New antibiotic class
Scientists have developed Novltex, a new antibiotic with strong activity against multidrug-resistant bacteria like MRSA. It’s cheaper to make and highly effective in lab tests.
🔗 pubs.acs.org/doi/10.1021/...
#SciComm #Antibiotics #AMR 🧪
Scientists have developed Novltex, a new antibiotic with strong activity against multidrug-resistant bacteria like MRSA. It’s cheaper to make and highly effective in lab tests.
🔗 pubs.acs.org/doi/10.1021/...
#SciComm #Antibiotics #AMR 🧪
Novltex: A New Class of Antibiotics with Potent Activity against Multidrug-Resistant Bacterial Pathogens─Design, Synthesis, and Biological Evaluation
Increasing spread of multidrug-resistant (MDR) bacteria demands antibiotics that combine potent activity with scalable synthesis. Novo29 (clovibactin) is promising but suffers from low yield (1%), dep...
pubs.acs.org
September 20, 2025 at 6:21 PM
💊 New antibiotic class
Scientists have developed Novltex, a new antibiotic with strong activity against multidrug-resistant bacteria like MRSA. It’s cheaper to make and highly effective in lab tests.
🔗 pubs.acs.org/doi/10.1021/...
#SciComm #Antibiotics #AMR 🧪
Scientists have developed Novltex, a new antibiotic with strong activity against multidrug-resistant bacteria like MRSA. It’s cheaper to make and highly effective in lab tests.
🔗 pubs.acs.org/doi/10.1021/...
#SciComm #Antibiotics #AMR 🧪
October 6, 2025 at 2:50 PM
Very nice review on multi-drug resistant bacterial infections of the #IDSky Crew. some fantastic summary figures it there. Please tag the authors if they are on here :)
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
Multidrug-resistant Gram-negative bacterial infections
Multidrug-resistant Gram-negative bacterial infections cause significant morbidity
and mortality globally. These pathogens easily acquire antimicrobial resistance (AMR),
further highlighting their cli...
www.thelancet.com
January 20, 2025 at 9:11 PM
Very nice review on multi-drug resistant bacterial infections of the #IDSky Crew. some fantastic summary figures it there. Please tag the authors if they are on here :)
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
Researchers have found that multidrug-resistant bacteria from hospitals are also highly resistant to the common herbicide glyphosate. The study sparks concerns that exposure to the common chemical could be allowing drug-resistant bacteria to thrive.
#chemsky 🧪
#chemsky 🧪
Glyphosate could be boosting spread of multidrug-resistant bacteria
Extensive application of the weed killer in Argentina may be unintentionally selecting for bacteria already resistant to many antibiotics
cen.acs.org
March 28, 2026 at 4:28 PM
Researchers have found that multidrug-resistant bacteria from hospitals are also highly resistant to the common herbicide glyphosate. The study sparks concerns that exposure to the common chemical could be allowing drug-resistant bacteria to thrive.
#chemsky 🧪
#chemsky 🧪
🧵(1/6)
Time for a history lesson from your favorite public health nerds 🤓
After the USSR collapsed, Tuberculosis (TB) surged—especially in prisons. Treatment crumbled. Drug supplies dried up.
The result? A catastrophic outbreak of drug-resistant TB.
Time for a history lesson from your favorite public health nerds 🤓
After the USSR collapsed, Tuberculosis (TB) surged—especially in prisons. Treatment crumbled. Drug supplies dried up.
The result? A catastrophic outbreak of drug-resistant TB.
Prisons in Post-Soviet Russia Incubate
a Plague
The collapse of the Soviet health care system in the 1990s coupled with prisons releasing improperly treated inmates and endemic poverty escalated incidences of multidrug-resistant tuberculosis to epi...
www.scientificamerican.com
May 12, 2025 at 1:54 PM
🧵(1/6)
Time for a history lesson from your favorite public health nerds 🤓
After the USSR collapsed, Tuberculosis (TB) surged—especially in prisons. Treatment crumbled. Drug supplies dried up.
The result? A catastrophic outbreak of drug-resistant TB.
Time for a history lesson from your favorite public health nerds 🤓
After the USSR collapsed, Tuberculosis (TB) surged—especially in prisons. Treatment crumbled. Drug supplies dried up.
The result? A catastrophic outbreak of drug-resistant TB.
Merck discontinues imipenem-cilastatin plus relebactam, a combination agent primarily used to target multidrug-resistant Pseudomonas aeruginosa.
Apparently Merck is no longer supplying Recarbrio. “In an unexpected move, Merck discontinued an important antibiotic from the U.S. market earlier this month, underscoring concerns about the commitment large pharmaceutical companies are willing to make to a field that is crucial to public health”
Merck discontinues a crucial antibiotic despite concerns over superbug resistance
Merck discontinued Recarbio, an important antibiotic in the U.S., despite concerns over resistance to superbugs.
www.statnews.com
September 28, 2026 at 11:51 PM
Merck discontinues imipenem-cilastatin plus relebactam, a combination agent primarily used to target multidrug-resistant Pseudomonas aeruginosa.
Next, researchers evaluated how well lolamicin worked against the multi-drug-resistant clinical isolates. They found that “Lolamicin has activity against a panel of more than 130 multidrug-resistant clinical isolates,” so the drug showed great promise as an effective antibiotic.
June 11, 2024 at 4:01 PM
Next, researchers evaluated how well lolamicin worked against the multi-drug-resistant clinical isolates. They found that “Lolamicin has activity against a panel of more than 130 multidrug-resistant clinical isolates,” so the drug showed great promise as an effective antibiotic.
#IDSky #MedSky required reading:
Multidrug-resistant Gram-negative bacterial infections
Nenad Macesic, Anne-Catrin Uhlemann, Anton Peleg
Review in @thelancet.bsky.social
doi.org/10.1016/S014...
Multidrug-resistant Gram-negative bacterial infections
Nenad Macesic, Anne-Catrin Uhlemann, Anton Peleg
Review in @thelancet.bsky.social
doi.org/10.1016/S014...
January 17, 2025 at 2:21 PM
#IDSky #MedSky required reading:
Multidrug-resistant Gram-negative bacterial infections
Nenad Macesic, Anne-Catrin Uhlemann, Anton Peleg
Review in @thelancet.bsky.social
doi.org/10.1016/S014...
Multidrug-resistant Gram-negative bacterial infections
Nenad Macesic, Anne-Catrin Uhlemann, Anton Peleg
Review in @thelancet.bsky.social
doi.org/10.1016/S014...
High rates of multidrug-resistant bacteria found in West Bank hospitals
More than one third of the 10,007 bacterial isolates collected from 13 West Bank hospitals were classified as multidrug-resistant.
www.cidrap.umn.edu/a...
More than one third of the 10,007 bacterial isolates collected from 13 West Bank hospitals were classified as multidrug-resistant.
www.cidrap.umn.edu/a...
November 6, 2025 at 9:47 PM
High rates of multidrug-resistant bacteria found in West Bank hospitals
More than one third of the 10,007 bacterial isolates collected from 13 West Bank hospitals were classified as multidrug-resistant.
www.cidrap.umn.edu/a...
More than one third of the 10,007 bacterial isolates collected from 13 West Bank hospitals were classified as multidrug-resistant.
www.cidrap.umn.edu/a...
Did you know that if tuberculosis (TB) medicines are used incorrectly or if the treatment is stopped too soon, the antibiotics can lose their power?
Learn more about fighting multidrug-resistant TB.
Remember, TB is curable!
Learn more about fighting multidrug-resistant TB.
Remember, TB is curable!
March 24, 2026 at 8:25 AM
Did you know that if tuberculosis (TB) medicines are used incorrectly or if the treatment is stopped too soon, the antibiotics can lose their power?
Learn more about fighting multidrug-resistant TB.
Remember, TB is curable!
Learn more about fighting multidrug-resistant TB.
Remember, TB is curable!
3) A USAID memo estimated that cases of multidrug-resistant tuberculosis will rise by ~30%⬆️ in the next few years, an unprecedented regression in the history of humankind’s fight against the disease.
March 16, 2025 at 5:08 PM
3) A USAID memo estimated that cases of multidrug-resistant tuberculosis will rise by ~30%⬆️ in the next few years, an unprecedented regression in the history of humankind’s fight against the disease.
Ita already pretty bad and in the wild already. Completely controllable with antibiotics - but of you weaponozed it to be multidrug resistant - yeah. Black death all over again. WTF.
October 4, 2026 at 8:45 PM
Ita already pretty bad and in the wild already. Completely controllable with antibiotics - but of you weaponozed it to be multidrug resistant - yeah. Black death all over again. WTF.
Antimicrobial peptide delivery to lung as peptibody mRNA in anti-inflammatory lipids treats multidrug-resistant bacterial pneumonia - @yizhoudonglab.bsky.social @icahngenomics.bsky.social go.nature.com/3LZS6HD
Antimicrobial peptide delivery to lung as peptibody mRNA in anti-inflammatory lipids treats multidrug-resistant bacterial pneumonia - Nature Biotechnology
Antimicrobial peptides delivered to mouse lung as mRNA peptibodies eradicate multidrug-resistant pneumonia.
go.nature.com
November 26, 2025 at 3:11 PM
Antimicrobial peptide delivery to lung as peptibody mRNA in anti-inflammatory lipids treats multidrug-resistant bacterial pneumonia - @yizhoudonglab.bsky.social @icahngenomics.bsky.social go.nature.com/3LZS6HD
Analysis highlights bacterial contamination, multidrug-resistance, in retail meat samples
FDA data show over 1/3rd of US retail meat samples tested positive for potentially harmful bacteria, and nearly 1 in 4 bacterial isolates were multidrug-resistant.
www.cidrap.umn.edu/f...
FDA data show over 1/3rd of US retail meat samples tested positive for potentially harmful bacteria, and nearly 1 in 4 bacterial isolates were multidrug-resistant.
www.cidrap.umn.edu/f...
June 18, 2025 at 9:16 PM
Analysis highlights bacterial contamination, multidrug-resistance, in retail meat samples
FDA data show over 1/3rd of US retail meat samples tested positive for potentially harmful bacteria, and nearly 1 in 4 bacterial isolates were multidrug-resistant.
www.cidrap.umn.edu/f...
FDA data show over 1/3rd of US retail meat samples tested positive for potentially harmful bacteria, and nearly 1 in 4 bacterial isolates were multidrug-resistant.
www.cidrap.umn.edu/f...
Antibiotic resistance: it's complicated.
This study compared the prevalence of resistant E. coli strains to antibiotic use in UK and Norway. The relationship is there, but less clear than one would expect.
The researchers think that it's b/c of non-resistant strains outcompeting resistant strains.
🧪
This study compared the prevalence of resistant E. coli strains to antibiotic use in UK and Norway. The relationship is there, but less clear than one would expect.
The researchers think that it's b/c of non-resistant strains outcompeting resistant strains.
🧪
Modulation of multidrug-resistant clone success in Escherichia coli populations: a longitudinal, mul...
The effect of antibiotic usage on the success of multidrug-resistant (MDR) clones in a population remains unclear. With this genomics-based molecular …
www.sciencedirect.com
January 12, 2024 at 7:04 AM
Antibiotic resistance: it's complicated.
This study compared the prevalence of resistant E. coli strains to antibiotic use in UK and Norway. The relationship is there, but less clear than one would expect.
The researchers think that it's b/c of non-resistant strains outcompeting resistant strains.
🧪
This study compared the prevalence of resistant E. coli strains to antibiotic use in UK and Norway. The relationship is there, but less clear than one would expect.
The researchers think that it's b/c of non-resistant strains outcompeting resistant strains.
🧪
Last month the WHO recommended three new regimens for multidrug-resistant tuberculosis. It's a big breakthrough—the new regimens allow patients to be cured in nine months with all-oral treatments.
https://buff.ly/4dpP5bz
#ShareGoodNewsToo
https://buff.ly/4dpP5bz
#ShareGoodNewsToo
Major advance in the fight against MDR-TB: four new short and effective treatments from recent clinical trials approved by the WHO
Boston, 19 August 2024 – Today, in a rapid communication, the World Health Organization (WHO) recommended 3 new regimens for multidrug- or rifampicin-resistant tuberculosis (MDR/RR-TB), which were…
buff.ly
October 3, 2024 at 1:50 PM
Last month the WHO recommended three new regimens for multidrug-resistant tuberculosis. It's a big breakthrough—the new regimens allow patients to be cured in nine months with all-oral treatments.
https://buff.ly/4dpP5bz
#ShareGoodNewsToo
https://buff.ly/4dpP5bz
#ShareGoodNewsToo
December 30, 2025 at 6:19 AM
34ème rétractation pour l'IHU et toujours 29ème pour Raoult.
RETRACTED ARTICLE: Pulmonary Isolation of Multidrug resistant “Mycobacterium simulans” and Mycobacterium tuberculosis from a patient in the Horn of Africa
www.nature.com/articles/s41...
RETRACTED ARTICLE: Pulmonary Isolation of Multidrug resistant “Mycobacterium simulans” and Mycobacterium tuberculosis from a patient in the Horn of Africa
www.nature.com/articles/s41...
RETRACTED ARTICLE: Pulmonary Isolation of Multidrug resistant “Mycobacterium simulans” and Mycobacterium tuberculosis from a patient in the Horn of Africa - Scientific Reports
Scientific Reports - RETRACTED ARTICLE: Pulmonary Isolation of Multidrug resistant “Mycobacterium simulans” and Mycobacterium tuberculosis from a patient in the Horn of Africa
www.nature.com
December 28, 2024 at 12:02 AM
34ème rétractation pour l'IHU et toujours 29ème pour Raoult.
RETRACTED ARTICLE: Pulmonary Isolation of Multidrug resistant “Mycobacterium simulans” and Mycobacterium tuberculosis from a patient in the Horn of Africa
www.nature.com/articles/s41...
RETRACTED ARTICLE: Pulmonary Isolation of Multidrug resistant “Mycobacterium simulans” and Mycobacterium tuberculosis from a patient in the Horn of Africa
www.nature.com/articles/s41...
Multidrug-resistant (MDR) & extensively drug-resistant (XDR) Shigella infections are increasing in Europe.
Since 2023, > 2 300 infections linked to 7 distinct resistant Shigella clusters have been reported in Europe and the US, particularly among gay, bisexual & other men who have sex with men.
Since 2023, > 2 300 infections linked to 7 distinct resistant Shigella clusters have been reported in Europe and the US, particularly among gay, bisexual & other men who have sex with men.
ECDC warns of growing spread of multidrug-resistant Shigella in Europe
ECDC is warning of the increasing spread of multidrug-resistant (MDR) and extensively drug-resistant (XDR) Shigella infections across Europe, particularly among men who have sex with men.
bit.ly
May 21, 2026 at 9:20 PM
Multidrug-resistant (MDR) & extensively drug-resistant (XDR) Shigella infections are increasing in Europe.
Since 2023, > 2 300 infections linked to 7 distinct resistant Shigella clusters have been reported in Europe and the US, particularly among gay, bisexual & other men who have sex with men.
Since 2023, > 2 300 infections linked to 7 distinct resistant Shigella clusters have been reported in Europe and the US, particularly among gay, bisexual & other men who have sex with men.
Also this year, the WHO recommended three new oral regimens for multidrug-resistant TB - allowing patients to be cured in nine months compared to the current, conventional 18-month regimen, which includes daily painful injections. https://buff.ly/4dpP5bz
#ShareGoodNewsToo
#ShareGoodNewsToo
Major advance in the fight against MDR-TB: four new short and effective treatments from recent clinical trials approved by the WHO
Boston, 19 August 2024 – Today, in a rapid communication, the World Health Organization (WHO) recommended 3 new regimens for multidrug- or rifampicin-resistant tuberculosis (MDR/RR-TB), which were…
buff.ly
January 11, 2025 at 2:50 PM
Also this year, the WHO recommended three new oral regimens for multidrug-resistant TB - allowing patients to be cured in nine months compared to the current, conventional 18-month regimen, which includes daily painful injections. https://buff.ly/4dpP5bz
#ShareGoodNewsToo
#ShareGoodNewsToo
Top 4 infectious disease fears:
Prions
Hantavirus
Rabies
Multidrug-resistant bacteria
Prions
Hantavirus
Rabies
Multidrug-resistant bacteria
Hantavirus is no joke. A friend I was visiting in Nevada had just spring cleaned a shed on her ranch and complained about feeling a little ill. We said goodbye. Three days later she was dead.
(AFP) - Three people have died on a cruise ship in the Atlantic, the WHO said Sunday, one a confirmed case of hantavirus -- an illness usually transmitted to humans from rodents.
www.yahoo.com/news/article...
www.yahoo.com/news/article...
May 3, 2026 at 8:32 PM
Top 4 infectious disease fears:
Prions
Hantavirus
Rabies
Multidrug-resistant bacteria
Prions
Hantavirus
Rabies
Multidrug-resistant bacteria
Study shows high rate of multidrug-resistant bacteria in hospitalized Ukrainian refugees
Among Ukrainian refugees treated at a Finnish hospital, 79% of those treated for war wounds carried multidrug-resistant bacteria.
www.cidrap.umn.edu/a...
Among Ukrainian refugees treated at a Finnish hospital, 79% of those treated for war wounds carried multidrug-resistant bacteria.
www.cidrap.umn.edu/a...
July 21, 2025 at 7:55 PM
Study shows high rate of multidrug-resistant bacteria in hospitalized Ukrainian refugees
Among Ukrainian refugees treated at a Finnish hospital, 79% of those treated for war wounds carried multidrug-resistant bacteria.
www.cidrap.umn.edu/a...
Among Ukrainian refugees treated at a Finnish hospital, 79% of those treated for war wounds carried multidrug-resistant bacteria.
www.cidrap.umn.edu/a...