#Multitarget
Hi @springernature.com
How come this article got published in Scientific Reports despite not meeting any of the criteria you claim to use for clinical trials?
pubpeer.com/publications...
#autism
PubPeer - Unveiling the multitarget mechanism of Liuwei Dihuang decoct...
There are comments on PubPeer for publication: Unveiling the multitarget mechanism of Liuwei Dihuang decoction in autism spectrum disorder via network pharmacology and molecular docking (2025)
pubpeer.com
December 6, 2025 at 1:44 PM
Huge thanks to J.Bewersdorf @fbzt.bsky.social A.Sentenac @vicidominilab.bsky.social for the super-resolution session #MiFobio2025 organized with @lydiadanglot.bsky.social @gdrimabio.bsky.social. Great overview of SMLM+3D/multitarget imaging, MinFlux, structured illumination towards RIM and ISM
October 12, 2025 at 9:14 AM
The new scroll system they added in I&II HD-2D is a fantastic way of adding more skills and spells to the game without completely overhauling the character's intended growth but Midenhall not getting any multitarget stuff and Cannock getting everything multitarget is a bit silly
November 7, 2025 at 5:11 PM
thinking about the mechanical trend of battle-groups replacing having 2d6+2 shitty little individual goblins, resolving swarms as single entities, and the weirdness that leads into with "AOE/Multitarget characters" not actually being better at dealing with the simplistic representation of a Horde
February 21, 2026 at 11:56 PM
Zenti has a fireball if you have a multitarget situation that needs a solution! - #furryart #slatepaw #stormbreak
February 20, 2026 at 9:18 PM
One of the most fun recent projects is our paper "AlphaFold Meets De Novo Drug Design: Leveraging Structural Protein Information in Multitarget Molecular Generative Models" by Andrius Bernatavicius. We show that the combined network learns target related chemical space.
pubs.acs.org/doi/10.1021/...
AlphaFold Meets De Novo Drug Design: Leveraging Structural Protein Information in Multitarget Molecular Generative Models
Recent advancements in deep learning and generative models have significantly expanded the applications of virtual screening for drug-like compounds. Here, we introduce a multitarget transformer model, PCMol, that leverages the latent protein embeddings derived from AlphaFold2 as a means of conditioning a de novo generative model on different targets. Incorporating rich protein representations allows the model to capture their structural relationships, enabling the chemical space interpolation of active compounds and target-side generalization to new proteins based on embedding similarities. In this work, we benchmark against other existing target-conditioned transformer models to illustrate the validity of using AlphaFold protein representations over raw amino acid sequences. We show that low-dimensional projections of these protein embeddings cluster appropriately based on target families and that model performance declines when these representations are intentionally corrupted. We also show that the PCMol model generates diverse, potentially active molecules for a wide array of proteins, including those with sparse ligand bioactivity data. The generated compounds display higher similarity known active ligands of held-out targets and have comparable molecular docking scores while maintaining novelty. Additionally, we demonstrate the important role of data augmentation in bolstering the performance of generative models in low-data regimes. Software package and AlphaFold protein embeddings are freely available at https://github.com/CDDLeiden/PCMol.
pubs.acs.org
November 30, 2024 at 7:46 AM
finished somethiiiiing! my very favorite persona healer so far, yukiko amagi! seriously idk why she gets both the best healing spell AND the only t4 multitarget skill you gcan get in the game. but you know what? good for her. she deserves it. weirdgirl swag.
January 18, 2025 at 1:28 AM
my coach yelled at me because i repeatedly kept trying to icicle dart, completely forgetting the fact tjat i have multitarget leaf. i like my coach :]
May 24, 2026 at 3:28 PM
Our team members @iratiijurco.bsky.social and Maite Lacuesta teamed up with the IBeA group to analyse lettuce 🥬 bioassays in antimicrobial-contaminated 🦠 soils, revealing their transfer to the lettuce🥬, but also their degradation. #SoilHealth

Check it out here:
www.sciencedirect.com/science/arti...
Multitarget and suspect-screening of antimicrobials in vegetables samples: Uptake experiments and identification of transformation products
This work provided an accurate analytical method to perform a multitarget analysis of a variety of antimicrobials (AMs) including sulfonamides, tetrac…
www.sciencedirect.com
January 17, 2025 at 1:46 PM
Double the Firepower: How to Master the ‘Multitarget Kill’ Ability in Ghost Justice

techmash.co.uk/2026/08/05/d...

@techmashcouk #GhostJustice #GamingNews #TacticalGaming #PCGaming #SteamWishlist #StrategyGames #IndieGames #TechMash
August 5, 2026 at 11:13 AM
(And of course the PC has a good Edge stat that makes the single-target ability free and makes the multitarget ability only cost 1 point. So you can single-blast all day long, or multi-blast at a low cost and slowly deplete yourself.)
August 12, 2026 at 8:40 PM
Optimization and Metabolomic Profiling of Wolffia globosa Extract Reveal Multitarget Neuroprotective Activity Against Alzheimer's Disease with In Vitro, In Silico, and In Vivo Validation
#Drosophila
Optimization and Metabolomic Profiling of <em>Wolffia globosa</em> Extract Reveal Multitarget Neuroprotective Activity Against Alzheimer's Disease with In Vitro, In Silico, and In Vivo Validation #Drosophila
PubMed link
pubmed.ncbi.nlm.nih.gov
September 26, 2026 at 10:23 AM
Now a contributed talk by Rohin E. McIntosh from @yale.edu about multitarget spatiotemporal power deposition inside diffusive media. From diffusive to decisive media!
May 8, 2026 at 9:33 AM
One assault. Two eliminations.

Multitarget Kill adds another layer of tactical depth to Ghost Justice.

Read more:
store.steampowered.com/news/app/417...

#GhostJustice #TurnBasedTactics #IndieGame
August 4, 2026 at 10:31 AM
Still cant believe Mega Emboar has fucking MOLD BREAKER as an ability while the other two got custom abilities. Like idk, an ability that turns multitarget attacks into singletarget and increases the damage when in doubles? Idk anything to give it something original.

Or at worst give it Sheer Force
August 9, 2026 at 3:31 AM
Fell Seal update: Final boss time!

Attempt #1: multitarget counters upon death kick my ass

Attempt #2: game crashes after I try to load it up after eating dinner

Attempt #3: the final boss uses HP-1 on me right before the 'low multitarget damage' move goes off. i am slain
November 24, 2024 at 2:55 AM
Projected impact & cost-effectiveness of new screening tests for colorectal cancer

Colonoscopy & FIT ⬆️ effective & ⬇️ costly than cell-free blood & multitarget stool DNA tests

Multitarget stool DNA test ⬆️ effective & ⬇️ costly than cell-free blood test

www.acpjournals.org/doi/10.7326/... #GastroSky
Projected Impact and Cost-Effectiveness of Novel Molecular Blood-Based or Stool-Based Screening Tests for Colorectal Cancer | Annals of Internal Medicine
Background: Cell-free DNA blood tests (cf-bDNA) and next-generation stool tests could change colorectal cancer (CRC) screening. Objective: To estimate the clinical and economic impacts of novel CRC sc...
www.acpjournals.org
November 24, 2024 at 6:37 PM
Macrophage-augmented organoids recapitulate the complex pathophysiology of viral diseases and enable development of multitarget therapeutics @natbiomedeng.nature.com
www.nature.org/articles/s41...
June 13, 2025 at 2:47 PM
relatedly i remember really liking, in lufia 1, multitarget spells playing out their animations and displaying their damage numbers one by one. in the wrong context that would be incredibly tedious, but since i was actually invested in the outcome, drawing it out gave me time to feel the drama of it
February 10, 2026 at 6:21 PM
Diría que hay 2 ligeras diferencias del combate de FES y los siguientes juegos, los ataques multitarget no te dan un turno extra y se tarda un turno entero en levantarse
Parecerá poco pero explican muchas cosas
October 30, 2024 at 7:08 PM
yeah, since the other raids have had multitarget fights, I was thinking a dual target Odin/Alexander fight would be so dope.
January 3, 2026 at 1:45 PM
also it would make the multitarget stuff kind of unwieldy but maybe that's cool
May 2, 2025 at 5:42 AM