Patterned brain stimulation is commonly employed to modulate brain circuits and treat neuropsychiatric disorders. Although it is widely used in clinical settings, there remains limited understanding of how stimulation alters neural oscillations and how these effects relate to baseline evoked network responses. To address this question, we applied 15 min of 10-Hz focal electrical stimulation delivered as 5-s trains separated by 10-s rest intervals, a pattern resembling “excitatory” transcranial magnetic stimulation, to 14 patients with epilepsy undergoing intracranial electroencephalography in premotor, parietal, and temporal cortical sites. We quantified spectral features of cortico-cortical evoked potentials (CCEPs) before and after stimulation. We hypothesized that the temporal and spectral components of the CCEP predicted the location and degree of stimulation-induced modulation. Across patients, low-frequency power (alpha, beta) showed the broadest change, whereas the magnitude of change was stronger in high frequencies (beta, gamma). Next, we demonstrated that regions with stronger prestimulation evoked spectral responses were more likely to exhibit larger poststimulation spectral changes. These findings were specific to frequency in a temporal window. Poststimulation power changes were driven by interaction between direction of change in prestimulation power and temporal window. Finally, regions exhibiting early increases and late decreases in prestimulation power exhibited power changes after stimulation. These patterns were consistent across premotor, parietal, and temporal sites, but the magnitude and latency varied by stimulation location. Together, these findings demonstrate that time-frequency prestimulation features predict poststimulation modulation of human neural oscillations and highlight temporally specific, state-dependent properties of stimulation responses in humans, thereby improving our understanding of stimulation-associated changes in human brain networks and helping inform more effective brain stimulation techniques. NEW & NOTEWORTHY Brain stimulation treats neuropsychiatric disorders, yet spectral changes remain poorly understood. We performed patterned stimulation in epilepsy patients, using intracranial recordings to study oscillatory plasticity. We found predictable changes: low frequencies were widespread, whereas high frequencies showed greater magnitude. These shifts were predicted by prestimulation activity. Our study reveals that baseline brain states determine spectral plasticity, providing insights to optimize stimulation techniques and understand human brain dynamics.

For six years, Mahir Munot couldn't make a first impression because the rumours made it for him. This is the story of what it took to get his voice back. Mahir Munot is a journalism and law student at UTS, a Headspace youth advisor, R U OK? ambassador, and TEDxSydney Youth speaker. In this conversation with Mark Henderson, he walks back through his high school years at a small, high-performing Sydney boys school: the six years of bullying that wore him down without ever quite becoming physical, until the day before his HSC exams when it did. He talks about why he stayed, how he compartmentalised, and the two things that eventually broke the silence: a stranger on a bus, and a mum who knew her son. He also talks about what came after, including journalism, law, a nine-day volunteer road trip with eighty strangers, and the voice that had been waiting for somewhere safe to go. In this conversation - Why the rumours do more damage than the bullying itself, and the preformed narrative effect - How Mahir compartmentalised six years of exclusion to protect his academic future - The day-before-HSC water fight that turned into fifteen boys chasing him across the oval - The stranger on the bus who wouldn't let him keep it to himself - The Big Lift: nine days, eighty strangers, and closing the loop on friendship Mahir's direct message: use your voice to uplift, not to drown Chapters 00:00 Introduction 02:17 Primary school: energy and curiosity 03:08 Year 7: a broken arm and a new school 06:35 The preformed narrative 10:22 Why he stayed 12:18 The water fight before the HSC 15:27 The stranger on the bus 22:52 Journalism and the voice uncaged 30:51 The Big Lift: nine days, eighty strangers 40:28 Use your voice to uplift

¿Vas a conocer Schaffhausen o Escafusa? Te contamos qué ver y hacer en Schaffhausen o Escafusa en Suiza muy cerca de la selva negra.

Munot emphasized that subscribing to IPOs is not the only path to generating returns in the capital markets, warning investors against misinterpreting the acronym as an "instant profit opportunity."

Die Festung Munot: Besuche das Wahrzeichen von Schaffhausen, steige auf den Wehrturm und geniesse die Aussicht auf Rhein und Altstadt.

Surat: A 26-year-old engineer lost Rs 13 lakh in a stock trading fraud after being lured with promises of high daily returns. The victim lodged an FIR on Friday at the Cybercrime police station, stating that he was defrauded between June 12 and Aug 22.According to the complaint, the engineer searched online for stock trading options. A few days later, he received a call from a woman who introduced herself as Siddhi Munot.

Bist du bereit die Zukunft der Stadt Schaffhausen mitzugestalten? An den malerischen Hängen am Fusse unseres Wahrzeichens Munot sowie an der ...

For six years, Mahir Munot couldn't make a first impression because the rumours made it for him. This is the story of what it took to get his voice back. Mahir Munot is a journalism and law student at UTS, a Headspace youth advisor, R U OK? ambassador, and TEDxSydney Youth speaker. In this conversation with Mark Henderson, he walks back through his high school years at a small, high-performing Sydney boys school: the six years of bullying that wore him down without ever quite becoming physical, until the day before his HSC exams when it did. He talks about why he stayed, how he compartmentalised, and the two things that eventually broke the silence: a stranger on a bus, and a mum who knew her son. He also talks about what came after, including journalism, law, a nine-day volunteer road trip with eighty strangers, and the voice that had been waiting for somewhere safe to go. In this conversation - Why the rumours do more damage than the bullying itself, and the preformed narrative effect - How Mahir compartmentalised six years of exclusion to protect his academic future - The day-before-HSC water fight that turned into fifteen boys chasing him across the oval - The stranger on the bus who wouldn't let him keep it to himself - The Big Lift: nine days, eighty strangers, and closing the loop on friendship Mahir's direct message: use your voice to uplift, not to drown Chapters 00:00 Introduction 02:17 Primary school: energy and curiosity 03:08 Year 7: a broken arm and a new school 06:35 The preformed narrative 10:22 Why he stayed 12:18 The water fight before the HSC 15:27 The stranger on the bus 22:52 Journalism and the voice uncaged 30:51 The Big Lift: nine days, eighty strangers 40:28 Use your voice to uplift

¿Vas a conocer Schaffhausen o Escafusa? Te contamos qué ver y hacer en Schaffhausen o Escafusa en Suiza muy cerca de la selva negra.