The shots are coming from inside the myocardium.
April 26, 2026 at 1:07 AM
The shots are coming from inside the myocardium.
Stoked to present our latest, superbly led by Chris et al & @torres-sanchez.bsky.social We tackled a fundamental problem – how tissues are patterned during development – found that geometry-constrained ECM fractures pattern the myocardium in the vertebrate heart 1/n www.biorxiv.org/content/10.1...
March 10, 2025 at 2:43 AM
Stoked to present our latest, superbly led by Chris et al & @torres-sanchez.bsky.social We tackled a fundamental problem – how tissues are patterned during development – found that geometry-constrained ECM fractures pattern the myocardium in the vertebrate heart 1/n www.biorxiv.org/content/10.1...
Originalpublikation: onlinelibrary.wiley.com/doi/full/10....
Anatomy of the heart with the highest heart rate
Chang et al. investigate the hearts of shrews, the mammals with the greatest heart rate. Mostly, the hearts have the expected anatomical traits, but the extent of the myocardium in the pulmonary vein...
onlinelibrary.wiley.com
September 21, 2025 at 10:33 AM
Originalpublikation: onlinelibrary.wiley.com/doi/full/10....
Happy Myocardium Day 🫀❣️ (watch out for the arrows, they may be lethal i fear)
February 14, 2025 at 6:09 PM
Happy Myocardium Day 🫀❣️ (watch out for the arrows, they may be lethal i fear)
Pls use every chance you get to remind Christian nationalists that the Bible says life begins at the first breath, not at the moment of fertilization of an egg or when electrical activity is detectable in fetal myocardium. So if they say/do/believe otherwise then they must think the Bible is wrong!
March 16, 2024 at 2:55 AM
Pls use every chance you get to remind Christian nationalists that the Bible says life begins at the first breath, not at the moment of fertilization of an egg or when electrical activity is detectable in fetal myocardium. So if they say/do/believe otherwise then they must think the Bible is wrong!
💥 ❤️🔥 🧪 Gene Therapy to Improve Heart Function After Heart Attacks
September 13, 2025 at 1:09 PM
💥 ❤️🔥 🧪 Gene Therapy to Improve Heart Function After Heart Attacks
New @science.org
A peptide released from white blood cells, directed against bacteria, can also poke holes in the membrane of heart muscle cells and induce a lethal arrhythmia (ventricular tachycardia). In the mouse model.
www.science.org/doi/10.1126/...
A peptide released from white blood cells, directed against bacteria, can also poke holes in the membrane of heart muscle cells and induce a lethal arrhythmia (ventricular tachycardia). In the mouse model.
www.science.org/doi/10.1126/...
Resistin-like molecule γ attacks cardiomyocyte membranes and promotes ventricular tachycardia
Ventricular tachycardia disrupts the heart’s coordinated pump function, leading to sudden cardiac death. Neutrophils, which are recruited in high numbers to the ischemic myocardium, promote these arrh...
www.science.org
September 4, 2025 at 6:03 PM
New @science.org
A peptide released from white blood cells, directed against bacteria, can also poke holes in the membrane of heart muscle cells and induce a lethal arrhythmia (ventricular tachycardia). In the mouse model.
www.science.org/doi/10.1126/...
A peptide released from white blood cells, directed against bacteria, can also poke holes in the membrane of heart muscle cells and induce a lethal arrhythmia (ventricular tachycardia). In the mouse model.
www.science.org/doi/10.1126/...
Excited to see (newly Dr) Greg Milburn's paper on cardiac amyloidosis in human myocardium with cell-level mechanics, histology, and gel-based analysis of sarcomeric proteins.
Myocardium From Patients With ATTR Amyloidosis Produces Less Force Secondary to Increased Fibrosis
doi.org/10.1016/j.ja...
Myocardium From Patients With ATTR Amyloidosis Produces Less Force Secondary to Increased Fibrosis
doi.org/10.1016/j.ja...
May 10, 2025 at 5:24 PM
Excited to see (newly Dr) Greg Milburn's paper on cardiac amyloidosis in human myocardium with cell-level mechanics, histology, and gel-based analysis of sarcomeric proteins.
Myocardium From Patients With ATTR Amyloidosis Produces Less Force Secondary to Increased Fibrosis
doi.org/10.1016/j.ja...
Myocardium From Patients With ATTR Amyloidosis Produces Less Force Secondary to Increased Fibrosis
doi.org/10.1016/j.ja...
“A heart scan. In layers.”
epicardium / myocardium / endocardium
#sherepoetry #poetry #poem #writingcommunity
epicardium / myocardium / endocardium
#sherepoetry #poetry #poem #writingcommunity
July 31, 2025 at 6:11 PM
“A heart scan. In layers.”
epicardium / myocardium / endocardium
#sherepoetry #poetry #poem #writingcommunity
epicardium / myocardium / endocardium
#sherepoetry #poetry #poem #writingcommunity
Tunneling nanotube–like structures regulate distant cellular interactions during heart formation | Science www.science.org/doi/10.1126/...
Tunneling nanotube–like structures regulate distant cellular interactions during heart formation
In the developing mammalian heart, the endocardium and the myocardium are separated by so-called cardiac jelly. Communication between the endocardium and the myocardium is essential for cardiac morpho...
www.science.org
March 13, 2025 at 7:54 PM
Tunneling nanotube–like structures regulate distant cellular interactions during heart formation | Science www.science.org/doi/10.1126/...
Hearts have topological defects. By treating the mouse myocardium as a 3D nematic, we found disclination lines threading through it. In situs inversus hearts, twist must match structural chirality for contraction to work, as found by quantifying the nematic chirality.
biorxiv.org/content/10.6...
biorxiv.org/content/10.6...
biorxiv.org
April 18, 2026 at 9:30 PM
Hearts have topological defects. By treating the mouse myocardium as a 3D nematic, we found disclination lines threading through it. In situs inversus hearts, twist must match structural chirality for contraction to work, as found by quantifying the nematic chirality.
biorxiv.org/content/10.6...
biorxiv.org/content/10.6...
Heart #Assembloid Vascularization (+pericyte coverage) & Innervation
1⃣#hiPSC-derived epicardium-myocardium #Organoid + 2⃣Sympathetic neuron #Spheroid
Beautiful vascular network!
Can we further differentiate it into A-C-V microcirculatory unit?😁
bioRxiv 2025
www.biorxiv.org/content/10.1...
1⃣#hiPSC-derived epicardium-myocardium #Organoid + 2⃣Sympathetic neuron #Spheroid
Beautiful vascular network!
Can we further differentiate it into A-C-V microcirculatory unit?😁
bioRxiv 2025
www.biorxiv.org/content/10.1...
January 18, 2025 at 12:44 PM
Heart #Assembloid Vascularization (+pericyte coverage) & Innervation
1⃣#hiPSC-derived epicardium-myocardium #Organoid + 2⃣Sympathetic neuron #Spheroid
Beautiful vascular network!
Can we further differentiate it into A-C-V microcirculatory unit?😁
bioRxiv 2025
www.biorxiv.org/content/10.1...
1⃣#hiPSC-derived epicardium-myocardium #Organoid + 2⃣Sympathetic neuron #Spheroid
Beautiful vascular network!
Can we further differentiate it into A-C-V microcirculatory unit?😁
bioRxiv 2025
www.biorxiv.org/content/10.1...
Awesome!
Tunneling nanotubes are getting to the mainstream high profile journals!
(21 years after the paper that coined the name #TunnelingNanotubes was published in Science)
#cytoskeleton
www.science.org/doi/10.1126/...
Tunneling nanotubes are getting to the mainstream high profile journals!
(21 years after the paper that coined the name #TunnelingNanotubes was published in Science)
#cytoskeleton
www.science.org/doi/10.1126/...
Tunneling nanotube–like structures regulate distant cellular interactions during heart formation
In the developing mammalian heart, the endocardium and the myocardium are separated by so-called cardiac jelly. Communication between the endocardium and the myocardium is essential for cardiac morpho...
www.science.org
March 15, 2025 at 2:14 PM
Awesome!
Tunneling nanotubes are getting to the mainstream high profile journals!
(21 years after the paper that coined the name #TunnelingNanotubes was published in Science)
#cytoskeleton
www.science.org/doi/10.1126/...
Tunneling nanotubes are getting to the mainstream high profile journals!
(21 years after the paper that coined the name #TunnelingNanotubes was published in Science)
#cytoskeleton
www.science.org/doi/10.1126/...
LIFE HACK: create a rhythmic tendency to depolarize throughout your myocardium so that the loss of a distinct pacemaker doesn’t completely halt the cardiac cycle.
July 30, 2023 at 6:11 PM
LIFE HACK: create a rhythmic tendency to depolarize throughout your myocardium so that the loss of a distinct pacemaker doesn’t completely halt the cardiac cycle.
Snap goes the pulmonary valve, crackle goes the cholesterol and pop goes the myocardium. Enjoy!
January 31, 2025 at 4:46 PM
Snap goes the pulmonary valve, crackle goes the cholesterol and pop goes the myocardium. Enjoy!
#DBfeature
Voltage-gated ion channel’s gene expression in the myocardium of embryo and adult chickens
by Elena Lebedeva et al
www.sciencedirect.com/science/arti...
Voltage-gated ion channel’s gene expression in the myocardium of embryo and adult chickens
by Elena Lebedeva et al
www.sciencedirect.com/science/arti...
December 16, 2024 at 1:20 PM
#DBfeature
Voltage-gated ion channel’s gene expression in the myocardium of embryo and adult chickens
by Elena Lebedeva et al
www.sciencedirect.com/science/arti...
Voltage-gated ion channel’s gene expression in the myocardium of embryo and adult chickens
by Elena Lebedeva et al
www.sciencedirect.com/science/arti...
I am hoping it’s his myocardium.
Clots and prayers.
Clots and prayers.
September 7, 2025 at 10:11 PM
I am hoping it’s his myocardium.
Clots and prayers.
Clots and prayers.
The most egregious part is when the revived person just gets up and continues the plot as if major trauma hasn't just been infliced on their ribs, intercostal muscles, and their myocardium.
Person after CPR belongs in hospital, not carrying a gun!
Person after CPR belongs in hospital, not carrying a gun!
August 13, 2025 at 6:08 AM
The most egregious part is when the revived person just gets up and continues the plot as if major trauma hasn't just been infliced on their ribs, intercostal muscles, and their myocardium.
Person after CPR belongs in hospital, not carrying a gun!
Person after CPR belongs in hospital, not carrying a gun!
Here we study the origin of the cardiac cell lineages in the mouse embryo. Separate but coordinated lineages independently specified at gastrulation generate the myocardium and endocardium. Credits: Miquel Sendra & coll: Jorge Dominguez, K. McDole and L. Guinard
authors.elsevier.com/sd/article/S...
authors.elsevier.com/sd/article/S...
ScienceDirect.com | Science, health and medical journals, full text articles and books.
authors.elsevier.com
May 27, 2025 at 3:18 PM
Here we study the origin of the cardiac cell lineages in the mouse embryo. Separate but coordinated lineages independently specified at gastrulation generate the myocardium and endocardium. Credits: Miquel Sendra & coll: Jorge Dominguez, K. McDole and L. Guinard
authors.elsevier.com/sd/article/S...
authors.elsevier.com/sd/article/S...
Restrictive Cardiomyopathy
- Normal systolic fx
- Small LV chamber size
- Granular myocardium
- Mild atrial enlargement
- Normal systolic fx
- Small LV chamber size
- Granular myocardium
- Mild atrial enlargement
November 29, 2024 at 6:20 PM
Restrictive Cardiomyopathy
- Normal systolic fx
- Small LV chamber size
- Granular myocardium
- Mild atrial enlargement
- Normal systolic fx
- Small LV chamber size
- Granular myocardium
- Mild atrial enlargement
NK cells are recruited to the ischemic myocardium in a CCR2-dependent manner, become activated, release granzyme B, promoting cardiomyocyte apoptosis, adverse ventricular remodeling, and impaired cardiac function @natcomms.nature.com @inserm.fr
www.nature.com/articles/s41...
www.nature.com/articles/s41...
April 2, 2026 at 2:17 AM
NK cells are recruited to the ischemic myocardium in a CCR2-dependent manner, become activated, release granzyme B, promoting cardiomyocyte apoptosis, adverse ventricular remodeling, and impaired cardiac function @natcomms.nature.com @inserm.fr
www.nature.com/articles/s41...
www.nature.com/articles/s41...
His myocardium.
January 4, 2026 at 2:06 AM
His myocardium.
I examined a native heart in a transplant patient who had previously undergone bone marrow injections into the scarred LV myocardium. By microscopy, there was hematopoiesis in the myocardial fibrosis. You are correct. Bone marrow cells are committed, and injections are voodoo medicine.
April 6, 2025 at 2:27 AM
I examined a native heart in a transplant patient who had previously undergone bone marrow injections into the scarred LV myocardium. By microscopy, there was hematopoiesis in the myocardial fibrosis. You are correct. Bone marrow cells are committed, and injections are voodoo medicine.