#SARS-CoV2 Herbstwelle, Österreich
Anstieg der respiratorischen Virusaktivität
Infektionsgeschehen wird dominiert durch #Rhinoviren
und #SARS-CoV-2
-saisonaleCoVs #NL63
-1 sporadischer #Influenzafall
#MonikaRedlberger #Sentinelsystem #MedUniWien #ZentrumVirologie
Anstieg der respiratorischen Virusaktivität
Infektionsgeschehen wird dominiert durch #Rhinoviren
und #SARS-CoV-2
-saisonaleCoVs #NL63
-1 sporadischer #Influenzafall
#MonikaRedlberger #Sentinelsystem #MedUniWien #ZentrumVirologie
September 26, 2025 at 6:17 PM
#SARS-CoV2 Herbstwelle, Österreich
Anstieg der respiratorischen Virusaktivität
Infektionsgeschehen wird dominiert durch #Rhinoviren
und #SARS-CoV-2
-saisonaleCoVs #NL63
-1 sporadischer #Influenzafall
#MonikaRedlberger #Sentinelsystem #MedUniWien #ZentrumVirologie
Anstieg der respiratorischen Virusaktivität
Infektionsgeschehen wird dominiert durch #Rhinoviren
und #SARS-CoV-2
-saisonaleCoVs #NL63
-1 sporadischer #Influenzafall
#MonikaRedlberger #Sentinelsystem #MedUniWien #ZentrumVirologie
Diese Woche im Sentinelsystem Österreich noch immer viele Rhinovirusinfektionen
- Rückgang der SARS-CoV2
Nachweise: Positivrate 9%
- Einige Parainfluenzafälle
- Saisonale Coronaviren (NL63)
- 2 Metapneumovirusfälle…
#DINÖ #MonikaRedlberger #ZentrumVirologie #MedUniWien
- Rückgang der SARS-CoV2
Nachweise: Positivrate 9%
- Einige Parainfluenzafälle
- Saisonale Coronaviren (NL63)
- 2 Metapneumovirusfälle…
#DINÖ #MonikaRedlberger #ZentrumVirologie #MedUniWien
November 15, 2024 at 5:56 PM
Diese Woche im Sentinelsystem Österreich noch immer viele Rhinovirusinfektionen
- Rückgang der SARS-CoV2
Nachweise: Positivrate 9%
- Einige Parainfluenzafälle
- Saisonale Coronaviren (NL63)
- 2 Metapneumovirusfälle…
#DINÖ #MonikaRedlberger #ZentrumVirologie #MedUniWien
- Rückgang der SARS-CoV2
Nachweise: Positivrate 9%
- Einige Parainfluenzafälle
- Saisonale Coronaviren (NL63)
- 2 Metapneumovirusfälle…
#DINÖ #MonikaRedlberger #ZentrumVirologie #MedUniWien
Update Infektionsgeschehen in Österreich
Entsprechend der Jahreszeit - hohe Aktivität saisonaler Coronaviren: 12% Positivrate im #Sentinelsystem
Vor allem deutlicher Anstieg von Infektionen mit HCoV-NL63 📈
1/2
Entsprechend der Jahreszeit - hohe Aktivität saisonaler Coronaviren: 12% Positivrate im #Sentinelsystem
Vor allem deutlicher Anstieg von Infektionen mit HCoV-NL63 📈
1/2
December 8, 2024 at 10:02 AM
Update Infektionsgeschehen in Österreich
Entsprechend der Jahreszeit - hohe Aktivität saisonaler Coronaviren: 12% Positivrate im #Sentinelsystem
Vor allem deutlicher Anstieg von Infektionen mit HCoV-NL63 📈
1/2
Entsprechend der Jahreszeit - hohe Aktivität saisonaler Coronaviren: 12% Positivrate im #Sentinelsystem
Vor allem deutlicher Anstieg von Infektionen mit HCoV-NL63 📈
1/2
Im #Sentinelsystem Österreich nachgewiesene Infektionen auch diese Woche großteils durch
Rhinoviren: 19% Positivrate
SARS-CoV2: 11%
Erhöhte Aktivität Parainfluenza-
und saisonale Coronaviren NL63
- RSV bisher nicht nachweisbar
- Ein sporadischer Influenza B Fall
#ZentrumVirologie #MedUniWien
Rhinoviren: 19% Positivrate
SARS-CoV2: 11%
Erhöhte Aktivität Parainfluenza-
und saisonale Coronaviren NL63
- RSV bisher nicht nachweisbar
- Ein sporadischer Influenza B Fall
#ZentrumVirologie #MedUniWien
November 24, 2024 at 8:36 AM
Im #Sentinelsystem Österreich nachgewiesene Infektionen auch diese Woche großteils durch
Rhinoviren: 19% Positivrate
SARS-CoV2: 11%
Erhöhte Aktivität Parainfluenza-
und saisonale Coronaviren NL63
- RSV bisher nicht nachweisbar
- Ein sporadischer Influenza B Fall
#ZentrumVirologie #MedUniWien
Rhinoviren: 19% Positivrate
SARS-CoV2: 11%
Erhöhte Aktivität Parainfluenza-
und saisonale Coronaviren NL63
- RSV bisher nicht nachweisbar
- Ein sporadischer Influenza B Fall
#ZentrumVirologie #MedUniWien
Das Sentinelsystem verzeichnet einen Anstieg der Einsendungen
Weiterhin hohe Rhinovirusaktivität
Anstieg von Infektionen mit Parainfluenzaviren und saisonalen Coronaviren NL63
SARS-C2 Nachweisrate sinkend
🔅Erster Nachweis von RSV in Wien und NÖ
#DINÖ #MonikaRedlberger #ZentrumVirologie #MedUniWien
Weiterhin hohe Rhinovirusaktivität
Anstieg von Infektionen mit Parainfluenzaviren und saisonalen Coronaviren NL63
SARS-C2 Nachweisrate sinkend
🔅Erster Nachweis von RSV in Wien und NÖ
#DINÖ #MonikaRedlberger #ZentrumVirologie #MedUniWien
November 29, 2024 at 8:38 PM
Das Sentinelsystem verzeichnet einen Anstieg der Einsendungen
Weiterhin hohe Rhinovirusaktivität
Anstieg von Infektionen mit Parainfluenzaviren und saisonalen Coronaviren NL63
SARS-C2 Nachweisrate sinkend
🔅Erster Nachweis von RSV in Wien und NÖ
#DINÖ #MonikaRedlberger #ZentrumVirologie #MedUniWien
Weiterhin hohe Rhinovirusaktivität
Anstieg von Infektionen mit Parainfluenzaviren und saisonalen Coronaviren NL63
SARS-C2 Nachweisrate sinkend
🔅Erster Nachweis von RSV in Wien und NÖ
#DINÖ #MonikaRedlberger #ZentrumVirologie #MedUniWien
Starke Zunahme der Influenza Virus Nachweise in Österreich
- 30 Influenza positive von 266 Sentinelproben - KW51📈Erhöhte Aktivität saisonaler Coronaviren NL63, OC43
Sporadische RSV-Nachweise
SARS-CoV2 weiterhin 8%
Rhinoviren leicht rückläufig
1/2
- 30 Influenza positive von 266 Sentinelproben - KW51📈Erhöhte Aktivität saisonaler Coronaviren NL63, OC43
Sporadische RSV-Nachweise
SARS-CoV2 weiterhin 8%
Rhinoviren leicht rückläufig
1/2
December 20, 2024 at 6:59 PM
Starke Zunahme der Influenza Virus Nachweise in Österreich
- 30 Influenza positive von 266 Sentinelproben - KW51📈Erhöhte Aktivität saisonaler Coronaviren NL63, OC43
Sporadische RSV-Nachweise
SARS-CoV2 weiterhin 8%
Rhinoviren leicht rückläufig
1/2
- 30 Influenza positive von 266 Sentinelproben - KW51📈Erhöhte Aktivität saisonaler Coronaviren NL63, OC43
Sporadische RSV-Nachweise
SARS-CoV2 weiterhin 8%
Rhinoviren leicht rückläufig
1/2
The S proteins of human coronavirus NL63 and severe acute respiratory syndrome coronavirus bind overlapping regions of ACE2
Reality check: the endemic coronavirus NL63 with its Spike protein bind the same human protein: ACE2, with overlapping regions
www.sciencedirect.co...
1/7
Reality check: the endemic coronavirus NL63 with its Spike protein bind the same human protein: ACE2, with overlapping regions
www.sciencedirect.co...
1/7
The S proteins of human coronavirus NL63 and severe acute respiratory syndrome coronavirus bind overlapping regions of ACE2
The cellular receptor for human coronavirus NL63 (HCoV-NL63), a group I coronavirus, is angiotensin-converting enzyme2 (ACE2). ACE2 is also the recept…
www.sciencedirect.com
September 4, 2025 at 10:51 AM
The S proteins of human coronavirus NL63 and severe acute respiratory syndrome coronavirus bind overlapping regions of ACE2
Reality check: the endemic coronavirus NL63 with its Spike protein bind the same human protein: ACE2, with overlapping regions
www.sciencedirect.co...
1/7
Reality check: the endemic coronavirus NL63 with its Spike protein bind the same human protein: ACE2, with overlapping regions
www.sciencedirect.co...
1/7
No, it is just another variant. We do not panic, just as we do not for variants and mutations in OC43, 229E, HKU.1, NL63, RSV, seasonalç Influenza strains, etc. These are panic accounts that spread fear for clicks.
May 25, 2025 at 6:30 PM
No, it is just another variant. We do not panic, just as we do not for variants and mutations in OC43, 229E, HKU.1, NL63, RSV, seasonalç Influenza strains, etc. These are panic accounts that spread fear for clicks.
Long COVID wird uns erhalten bleiben – auch bei Kindern.
Kontext: Genau wie Langzeitfolgen von RSV, OC43, NL63, Influenza, EBV usw. werden sie sehr selten, aber vorhanden sein. Therapeutische Optionen müssen entwickelt werden.
#LongCovidkids
Kontext: Genau wie Langzeitfolgen von RSV, OC43, NL63, Influenza, EBV usw. werden sie sehr selten, aber vorhanden sein. Therapeutische Optionen müssen entwickelt werden.
#LongCovidkids
October 3, 2025 at 3:38 AM
Long COVID wird uns erhalten bleiben – auch bei Kindern.
Kontext: Genau wie Langzeitfolgen von RSV, OC43, NL63, Influenza, EBV usw. werden sie sehr selten, aber vorhanden sein. Therapeutische Optionen müssen entwickelt werden.
#LongCovidkids
Kontext: Genau wie Langzeitfolgen von RSV, OC43, NL63, Influenza, EBV usw. werden sie sehr selten, aber vorhanden sein. Therapeutische Optionen müssen entwickelt werden.
#LongCovidkids
3) Infecting this many people this frequently:
-Influenza A H1N1
-Influenza A H3N2
- Influenza B/Victoria
-OC43, NL63, 229E, HKU.1
-RSV
-~160 rhinoviruses
-adenoviruses
-etc, etc
2/2
-Influenza A H1N1
-Influenza A H3N2
- Influenza B/Victoria
-OC43, NL63, 229E, HKU.1
-RSV
-~160 rhinoviruses
-adenoviruses
-etc, etc
2/2
October 13, 2025 at 8:38 AM
3) Infecting this many people this frequently:
-Influenza A H1N1
-Influenza A H3N2
- Influenza B/Victoria
-OC43, NL63, 229E, HKU.1
-RSV
-~160 rhinoviruses
-adenoviruses
-etc, etc
2/2
-Influenza A H1N1
-Influenza A H3N2
- Influenza B/Victoria
-OC43, NL63, 229E, HKU.1
-RSV
-~160 rhinoviruses
-adenoviruses
-etc, etc
2/2
May want to watch SA. This is the single genetic change that has the potential to de attenuate clinical severity of covid to that of NL63 and dramatically reduce the frequency of LC. Or it becomes like the Feline and Porcine corona, and everyone melts from inside 🤣.
September 26, 2025 at 11:32 AM
May want to watch SA. This is the single genetic change that has the potential to de attenuate clinical severity of covid to that of NL63 and dramatically reduce the frequency of LC. Or it becomes like the Feline and Porcine corona, and everyone melts from inside 🤣.
Pre-existing IgG antibodies to HCoVs NL63 and OC43 Spike increased during the pandemic and after COVID-19 vaccination
Antibodies to SARS-CoV-2, NL63 and OC43 were all raised during the pandemic and further enhanced after COVID-19 vaccinations.
www.cell.com/heliyon...
1/2
Antibodies to SARS-CoV-2, NL63 and OC43 were all raised during the pandemic and further enhanced after COVID-19 vaccinations.
www.cell.com/heliyon...
1/2
Pre-existing IgG antibodies to HCoVs NL63 and OC43 Spike increased during the pandemic and after COVID-19 vaccination
Preexisting immunity may be associated with increased protection against non-related
pathogens such as, SARS-CoV-2. There is little information regarding endemic human
coronaviruses (HCOVs) from Pakistan, which experienced a relatively low COVID-19 morbidity
and mortality. We investigated antibodies to SARS-CoV-2 and HCoVs NL63 and OC43, comparing
sera from prepandemic controls (PPC) period with responses in healthy controls from
the pandemic (HC 2021). Further, we investigated the effect of inactivated and mRNA
COVID-19 vaccinations on antibody responses to the pandemic and endemic coronaviruses.
www.cell.com
January 26, 2025 at 12:19 PM
Pre-existing IgG antibodies to HCoVs NL63 and OC43 Spike increased during the pandemic and after COVID-19 vaccination
Antibodies to SARS-CoV-2, NL63 and OC43 were all raised during the pandemic and further enhanced after COVID-19 vaccinations.
www.cell.com/heliyon...
1/2
Antibodies to SARS-CoV-2, NL63 and OC43 were all raised during the pandemic and further enhanced after COVID-19 vaccinations.
www.cell.com/heliyon...
1/2
Innate immune responses differ among coronaviruses: HCoV-229E and -NL63 activate strong interferon signals, while SARS-CoV-2 has moderate activation, and MERS-CoV nearly disables these defenses.
https://buff.ly/3BEMXzR
https://buff.ly/3BEMXzR
December 20, 2024 at 6:02 AM
Innate immune responses differ among coronaviruses: HCoV-229E and -NL63 activate strong interferon signals, while SARS-CoV-2 has moderate activation, and MERS-CoV nearly disables these defenses.
https://buff.ly/3BEMXzR
https://buff.ly/3BEMXzR
Check out the latest from @viralvaxlab.bsky.social postdoc Wen Shi Lee, developing monoclonal antibodies that neutralise the NL63 coronavirus!
Potent neutralising monoclonal antibodies targeting the spike of NL63 coronavirus
www.nature.com/articles/s44...
www.nature.com/articles/s44...
Potent neutralising monoclonal antibodies targeting the spike of NL63 coronavirus - npj Viruses
npj Viruses - Potent neutralising monoclonal antibodies targeting the spike of NL63 coronavirus
www.nature.com
April 25, 2025 at 11:54 PM
Check out the latest from @viralvaxlab.bsky.social postdoc Wen Shi Lee, developing monoclonal antibodies that neutralise the NL63 coronavirus!
New SARS-CoV-2 variants will keep coming, just like new influenza and RSV, OC43, NL63, etc variants. These can tell us something about the new variant and help plan new vaccines for vulnerable groups.
They do not spell doom, gloom or panic. They do not escape your immune system.
1/4
They do not spell doom, gloom or panic. They do not escape your immune system.
1/4
March 12, 2025 at 9:54 PM
New SARS-CoV-2 variants will keep coming, just like new influenza and RSV, OC43, NL63, etc variants. These can tell us something about the new variant and help plan new vaccines for vulnerable groups.
They do not spell doom, gloom or panic. They do not escape your immune system.
1/4
They do not spell doom, gloom or panic. They do not escape your immune system.
1/4
The RBD footprint is largely shared with ACE2-using sarbecoviruses and NL63. It does infect human cells.
2/2
2/2
February 19, 2025 at 9:57 PM
The RBD footprint is largely shared with ACE2-using sarbecoviruses and NL63. It does infect human cells.
2/2
2/2
We are excited to share our paper describing neutralising monoclonal antibodies against human coronavirus NL63, an alphacoronavirus that uses the same ACE2 receptor as SARS-CoV and SARS-CoV-2, but generally only causes mild respiratory illness. www.nature.com/articles/s44...
Potent neutralising monoclonal antibodies targeting the spike of NL63 coronavirus - npj Viruses
npj Viruses - Potent neutralising monoclonal antibodies targeting the spike of NL63 coronavirus
www.nature.com
May 1, 2025 at 4:06 AM
We are excited to share our paper describing neutralising monoclonal antibodies against human coronavirus NL63, an alphacoronavirus that uses the same ACE2 receptor as SARS-CoV and SARS-CoV-2, but generally only causes mild respiratory illness. www.nature.com/articles/s44...
No. NL63 also binds to ACE2. Influenza binds to a sugar proteins present on most or all cells, etc.
March 22, 2025 at 4:58 PM
No. NL63 also binds to ACE2. Influenza binds to a sugar proteins present on most or all cells, etc.
It is as if OC43, NL63, HKU1 and 229E did not accept SC2 into the same timeframe.
It will be interesting to see if this years SC2 peak is again earlier, from middel September to possibly August, or it may have found the best spot and middle of September is where it settles?
4/4
It will be interesting to see if this years SC2 peak is again earlier, from middel September to possibly August, or it may have found the best spot and middle of September is where it settles?
4/4
May 20, 2026 at 1:16 PM
It is as if OC43, NL63, HKU1 and 229E did not accept SC2 into the same timeframe.
It will be interesting to see if this years SC2 peak is again earlier, from middel September to possibly August, or it may have found the best spot and middle of September is where it settles?
4/4
It will be interesting to see if this years SC2 peak is again earlier, from middel September to possibly August, or it may have found the best spot and middle of September is where it settles?
4/4
Yes, SARS-CoV-2 binds to and uses the ACE2 protein to infect our cells.
Yes, coronavirus NL63 does this as well, the exact same ACE2 protein.
2/10
Yes, coronavirus NL63 does this as well, the exact same ACE2 protein.
2/10
February 13, 2026 at 5:48 PM
Yes, SARS-CoV-2 binds to and uses the ACE2 protein to infect our cells.
Yes, coronavirus NL63 does this as well, the exact same ACE2 protein.
2/10
Yes, coronavirus NL63 does this as well, the exact same ACE2 protein.
2/10
RFK Jr.; "attacks races"-
Due to ACE2? Does he know NL63 does the same?
3/5
Due to ACE2? Does he know NL63 does the same?
3/5
November 15, 2024 at 12:10 AM
RFK Jr.; "attacks races"-
Due to ACE2? Does he know NL63 does the same?
3/5
Due to ACE2? Does he know NL63 does the same?
3/5
HL2019's genome is similar to human coronaviruses HCoV 229E and NL63, raising concerns about potential cross-species transmission.
November 14, 2024 at 10:22 AM
HL2019's genome is similar to human coronaviruses HCoV 229E and NL63, raising concerns about potential cross-species transmission.
Potent neutralising monoclonal antibodies targeting the spike of NL63 coronavirus
www.nature.com/articles/s44...
www.nature.com/articles/s44...
Potent neutralising monoclonal antibodies targeting the spike of NL63 coronavirus - npj Viruses
npj Viruses - Potent neutralising monoclonal antibodies targeting the spike of NL63 coronavirus
www.nature.com
April 25, 2025 at 7:27 PM
Potent neutralising monoclonal antibodies targeting the spike of NL63 coronavirus
www.nature.com/articles/s44...
www.nature.com/articles/s44...
With the more well-known virus season approaching, this, unfortunately, will be a regular occurrence again. SARS-CoV-2, like OC43, NL63, HKU1, 229E, influenza viruses, RSV, etc., poses a risk. But this doesn´t need exaggeration for clicks!
Most will have immune memory.
Most will have immune memory.
Covid is on the rise in TX (and US, more so in South & West).
Covid and other respiratory viruses are a concern, and it's good to be aware of what's going on and take sensible precautions.
But, we can be certain 1 in 20 Texans do not have covid right now. This misinformation serves no one.
1/
Covid and other respiratory viruses are a concern, and it's good to be aware of what's going on and take sensible precautions.
But, we can be certain 1 in 20 Texans do not have covid right now. This misinformation serves no one.
1/
August 26, 2026 at 11:10 AM
With the more well-known virus season approaching, this, unfortunately, will be a regular occurrence again. SARS-CoV-2, like OC43, NL63, HKU1, 229E, influenza viruses, RSV, etc., poses a risk. But this doesn´t need exaggeration for clicks!
Most will have immune memory.
Most will have immune memory.
Why?
For the same reasons as we keep getting infected with many pathogens, including influenza, RSV, HSV, OC43, NL63, etc.
.
1) Antibody waning
2) Variant selection
1/2
For the same reasons as we keep getting infected with many pathogens, including influenza, RSV, HSV, OC43, NL63, etc.
.
1) Antibody waning
2) Variant selection
1/2
August 27, 2024 at 8:02 AM
Why?
For the same reasons as we keep getting infected with many pathogens, including influenza, RSV, HSV, OC43, NL63, etc.
.
1) Antibody waning
2) Variant selection
1/2
For the same reasons as we keep getting infected with many pathogens, including influenza, RSV, HSV, OC43, NL63, etc.
.
1) Antibody waning
2) Variant selection
1/2