#NanoTemper
Nanotemper #Prometheus looks so cool 😎
November 19, 2024 at 11:08 PM
#EBSA2025 is coming to an end with prizes from Nanotemper Avanti and EBSA young investigator
July 4, 2025 at 12:57 PM
250 scientists. 1 meetup. Infinite ideas. Mike Ouren takes us inside the SLAS Munich Meetup at NanoTemper HQ - where lab automation meets community.

🎧 Full episode drops Sunday: From Munich to Montreal on YouTube.com/@HelicalBrew

#HelicalBrew #SLAS #LabAutomation #ScienceMeansBusiness
October 23, 2025 at 10:38 PM
Congratulation to the marvellous Anyah Settle for her first PhD publication (and not finished yet!).
Fantastic collaborators @tucksengwong.bsky.social and @astra-zeneca.bsky.social . Thank you @royalsociety.org, BBSRC, AstraZeneca and NanoTemper Technologies for funding.
www.jbc.org/article/S002...
Cosolute effects reveal the nature of weak forces governing GLP-1 oligomer stability
Glucagon-like peptide-1 (GLP-1) is an incretin hormone widely used to manage diabetes and obesity through its ability to regulate glucose homeostasis. Clinically relevant GLP-1 sequences form oligomer...
www.jbc.org
April 26, 2026 at 8:03 AM
Any experience here with Alternative capillaries for Microscale Thermophoresis (MST, Nanotemper)? We tried some medical capillaries and a 3D printer holder which seem to work well
April 30, 2026 at 2:11 PM
Protein Purification and Biophysical Characterisation 2025 has come to a close. Thank you to all attendees for their attentive participation, with special mention to our Programme Coordinators, speakers and sponsors: Clinisciences, Nanotemper and Constant Systems. #BiochemEvent
July 2, 2025 at 2:00 PM
Unfortunately, the nanotemper system we are using does not allow adjustment of wavelengths. We could do it in a regular spectrophotometer at a much lower through-put though.
April 10, 2026 at 8:33 AM
Welcome to the herd @NanoTemper! We are proud to join you on your mission to enable everyone who is working with proteins to "always push the limits" and offer your customers a more convenient, customer-centric experience based on Spryker.
November 21, 2024 at 12:38 AM
Interested in #molecularglues?
Learn how #NanoTemper Dianthus affinity tech showed novel inhibitors, BLUEs, block interactions of BRISC with SHMT2.

BLUEs inhibit #protein complexes by inducing #PP!s

Many thanks to Elton Zeqiraj et al, @universityofleeds.bsky.social

www.nature.com/articles/s41...
Molecular glues that inhibit deubiquitylase activity and inflammatory signaling - Nature Structural & Molecular Biology
The BRCC36 isopeptidase complex (BRISC) is a deubiquitylase that stabilizes interferon receptors, driving inflammation. We discovered ‘BRISC molecular glue’ inhibitors (BLUEs) that selectively inactiv...
www.nature.com
March 20, 2025 at 10:27 PM
In #epitransciptomics, there is a need to measure #RNA-#protein interactions which can be problematic from RNA conformational dynamics.
The in-solution measurement on #NanoTemper Monolith X means biomolecules retain conformations for these studies
#biophysics

www.tandfonline.com/doi/full/10....
Mechanistic studies on HNRNPA2B1 suggest binding but not selective recognition of m6A
HNRNPA2B1 contains two RRM domains and has been investigated for its possible role as an m6A reader protein. The targetome of HNRNPA2B1 was shown to overlap with the m6A methylation motif, but furt...
www.tandfonline.com
March 12, 2026 at 10:21 PM
Visiting NanoTemper and siTOOls in Munich.
A few impressions from our M.Sc. Biochemistry industry excursion @uniregensburg.bsky.social, joined by exchange students from @colorado.edu. Great insights into how scientific ideas become products.
Many thanks to both companies for the warm welcome!😊
July 23, 2026 at 9:28 AM
🔬 Hands-on workshop alert!

Learn nanoDSF, DLS & Spectral Shift methods - and try them on your own samples at the NanoTemper Technologies in CMS workshop.

📅 May 5–6, 2026
📍 BIOCEV, Vestec

👉 More info: 1url.cz/2eEKO
April 22, 2026 at 10:02 AM
NanoTemper's Strategic Advancements in Biopharma Through Envue Acquisition and Dianthus α Launch#Germany#Munich#NanoTemper#Dianthus_α#Envue_Technologies
NanoTemper's Strategic Advancements in Biopharma Through Envue Acquisition and Dianthus α Launch
NanoTemper has enhanced its biopharma discovery portfolio by acquiring Envue Technologies and launching the innovative Dianthus α application, driving advancements in drug discovery.
third-news.com
November 5, 2025 at 3:26 PM
#FundaciónMEDINA NanoTemper Technologies Instituto de Química Física "Blas Cabrera" (IQF-CSIC) Universidad de Granada MSD España Junta de Andalucía #HighThroughputScreening #DrugDiscovery #MolecularInteractions #Biophysics #IQFSymposium
February 16, 2026 at 8:50 AM
These insights will drive our future projects and enhance our capabilities. Big thank you to the #NanoTemper Technologies team and to @eu-openscreen.bsky.social for their support. Stay tuned for impactful outcomes from MEDINA! #Biophysics #Innovation #Collaboration #Nanotemper #MolecularInteractions
May 20, 2025 at 11:47 AM
Next up ➡️ SLAS Munich with NanoTemper 🇩🇪 #SLAS #Munich #HelicalBrew
October 5, 2025 at 3:49 PM
What motivates you to start your own biotech company? Philipp Baaske, CEO of NanoTemper, spoke today at the PioneerCampus seminar about his journey from science to business - inspiring 🚀 #HelmholtzMunich #NanoTemper
February 4, 2025 at 3:21 PM
Studying #inflammasomes, caspase-4 & #pyroptosis? Learn how the binding affinities of #caspase-4 protein interaction with #lipopolysaccharide (micelles) was enabled by the in-solution measurement of a NanoTemper Technologies Monolith X spectral shift detection
Caspase-4 binds to LPS membranes with positive curvature for non-canonical inflammasome activation
The cytosolic LPS sensor caspase-4 controls antibacterial immunity by inducing pyroptosis and cytokine secretion. Began et al. show how remodeling of LPS membranes by interferon-induced GTPase GBP1 pr...
www.cell.com
March 1, 2026 at 8:34 PM
Working on #MHC-peptide presentation? Learn how NanoTemper Prometheus Panta label-free, high-throughput nanoDSF measures peptide binding strength via thermal stability (Tm) on HLA-E & Mamu-E.

Thanks to Geraldine Gillespie
#immunology #biophysics #peptide
onlinelibrary.wiley.com/doi/10.1002/...
Shared HLA‐E and Mamu‐E Peptide Repertoires With Subtle Peptide Binding Differences Revealed by Combined nDSF‐ and Fluorescence Polarisation‐Based Methods
The MHC-E peptide binding methods described here—nano-differential scanning fluorimetry and fluorescence polarisation—demonstrate shared peptide binding repertoires with subtle binding hierarchy diff....
onlinelibrary.wiley.com
January 25, 2026 at 5:21 PM
Many thanks to Charlotte Hunter, Stefanie Freitag-Pohl & Ehmke Pohl #Durhamuniversity for this review.
It candidly shows spectral shift detection on a #nanotemper Dianthus can #screen #macromolecular interactions in solution i.e. in (near to) natve conformation.
#biiphysics #drugdiscovery #hts
September 4, 2025 at 9:08 PM
Also, generating robust data requires high-quality platforms. At NanoTemper Technologies we see adoption of Prometheus Panta to produce #protein thermal & colloidal stability data for #biologic developability & feeding #AI/#ML tools for biologic attribute predictions

www.nature.com/articles/s41...
Calling all data - Nature Methods
As life sciences research becomes enmeshed in the age of AI, real experimental data are more valuable than ever.
www.nature.com
July 12, 2025 at 8:07 PM
Join us at the Stability & #screening in #drugdiscovery Regional Meeting:

You’ll hear real success stories, pick up useful tips, & explore how the right #biophysical tools can help your own #research.

📍 I-HUB, @imperialcollegeldn.bsky.social
📅 June 24, 2025

nanotempertech.com/events/excha...
Stability and Screening in Drug Discovery Regional User Meeting - NanoTemper Technologies
Connect, Learn, and Discover in London: Dive into protein stability and high-throughput screening solutions with engaging talks, peer exchange, and instrument showcases.
nanotempertech.com
June 7, 2025 at 12:00 PM
Webinar tomorrow: Learn how nanoDSF simplifies ID testing in biologics manufacturing.

Join Marius Müller from J & J as he shares how Prometheus Panta ensures accurate and reliable Drug Substance identification

📅 Tuesday, March 11: 9am PT | 12pm ET | 5pm CET

www.linkedin.com/posts/nanote...
Identification (ID) testing is a critical requirement in biologics… | NanoTemper Technologies
Identification (ID) testing is a critical requirement in biologics manufacturing, and scientists need robust and reliable methods to confidently identify Drug…
www.linkedin.com
March 10, 2025 at 7:35 PM
Working in #biologic manufacturing, #QC or #analytics & looking for novel approaches for ID testing? Then join this webinar to learn more:
www.linkedin.com/posts/nanote...
NanoTemper Technologies on LinkedIn: Identification (ID) testing is a critical requirement in biologics…
Identification (ID) testing is a critical requirement in biologics manufacturing, and scientists need robust and reliable methods to confidently identify Drug…
www.linkedin.com
March 6, 2025 at 9:36 PM