Wondering what papers did Nature Microbiology editors find super interesting (besides the cool content they are already handling!) ? 🤔
Check out #NatMicroPicks at @natmicrobiol.nature.com!
Check out #NatMicroPicks at @natmicrobiol.nature.com!
#NatMicroPicks
Synthetic evolution overdrive 🦠🔧🚅
A highly mutagenic DNA replication system speeds up evolution in Escherichia coli, without harming the host, opening a new way to accelerate protein engineering.
#SynBio #MicroSky
www.science.org/doi/10.1126/...
Synthetic evolution overdrive 🦠🔧🚅
A highly mutagenic DNA replication system speeds up evolution in Escherichia coli, without harming the host, opening a new way to accelerate protein engineering.
#SynBio #MicroSky
www.science.org/doi/10.1126/...
An orthogonal T7 replisome for continuous hypermutation and accelerated evolution in E. coli
Systems that perform continuous hypermutation of designated genes without compromising the integrity of the host genome can substantially accelerate the evolution of new or enhanced protein functions....
www.science.org
August 8, 2025 at 1:42 PM
Wondering what papers did Nature Microbiology editors find super interesting (besides the cool content they are already handling!) ? 🤔
Check out #NatMicroPicks at @natmicrobiol.nature.com!
Check out #NatMicroPicks at @natmicrobiol.nature.com!
#NatMicroPicks
Hidden in plain sight! 💊🦠
Assessing overlooked minor compounds uncovered a new antibiotic, manikomycin, from well-studied Streptomyces species that kills bacteria by uniquely targeting the ribosomal E-site
#MicroSky
www.nature.com/articles/s41...
Hidden in plain sight! 💊🦠
Assessing overlooked minor compounds uncovered a new antibiotic, manikomycin, from well-studied Streptomyces species that kills bacteria by uniquely targeting the ribosomal E-site
#MicroSky
www.nature.com/articles/s41...
A natural depsipeptide antibiotic binds the E-site of the bacterial ribosome - Nature
Improved fractionation strategies can identify antibiotics with previously unseen scaffolds and mechanisms, exemplified by manikomycin from Streptomyces rimosus, which acts by targeting the E-site of ...
www.nature.com
June 19, 2026 at 12:55 PM
#NatMicroPicks
Hidden in plain sight! 💊🦠
Assessing overlooked minor compounds uncovered a new antibiotic, manikomycin, from well-studied Streptomyces species that kills bacteria by uniquely targeting the ribosomal E-site
#MicroSky
www.nature.com/articles/s41...
Hidden in plain sight! 💊🦠
Assessing overlooked minor compounds uncovered a new antibiotic, manikomycin, from well-studied Streptomyces species that kills bacteria by uniquely targeting the ribosomal E-site
#MicroSky
www.nature.com/articles/s41...
#NatMicroPicks
A network like none other! 🌍🍄
Global data and modeling estimates that arbuscular mycorrhizal fungi form extensive underground networks that play a major role in plant carbon–nutrient exchange
#MicroSky
www.science.org/doi/10.1126/...
A network like none other! 🌍🍄
Global data and modeling estimates that arbuscular mycorrhizal fungi form extensive underground networks that play a major role in plant carbon–nutrient exchange
#MicroSky
www.science.org/doi/10.1126/...
Global density and biomass of arbuscular mycorrhizal fungal networks
Arbuscular mycorrhizal fungi form symbioses with ~70% of plant species, building hyphal networks that exchange nutrients for host-derived carbon. These tubular networks move ~1 billion metric tons of ...
www.science.org
June 19, 2026 at 12:51 PM
#NatMicroPicks
A network like none other! 🌍🍄
Global data and modeling estimates that arbuscular mycorrhizal fungi form extensive underground networks that play a major role in plant carbon–nutrient exchange
#MicroSky
www.science.org/doi/10.1126/...
A network like none other! 🌍🍄
Global data and modeling estimates that arbuscular mycorrhizal fungi form extensive underground networks that play a major role in plant carbon–nutrient exchange
#MicroSky
www.science.org/doi/10.1126/...
#NatMicroPicks
Phage-to-phage dialogue! 🗨️💬
Arbitrium peptide signaling systems in bacteriophages exhibit cross-communication where peptides can influence non-cognate receptors to promote lysogeny
#MicroSky
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Phage-to-phage dialogue! 🗨️💬
Arbitrium peptide signaling systems in bacteriophages exhibit cross-communication where peptides can influence non-cognate receptors to promote lysogeny
#MicroSky
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Arbitrium phages can manipulate each other’s lysis/lysogeny decisions
Arbitrium phages belonging to different species and genera can influence each other’s
infection dynamics by secreting chemically similar, non-cognate signal peptides. These
findings indicate that arbi...
www.cell.com
June 19, 2026 at 12:45 PM
#NatMicroPicks
Phage-to-phage dialogue! 🗨️💬
Arbitrium peptide signaling systems in bacteriophages exhibit cross-communication where peptides can influence non-cognate receptors to promote lysogeny
#MicroSky
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Phage-to-phage dialogue! 🗨️💬
Arbitrium peptide signaling systems in bacteriophages exhibit cross-communication where peptides can influence non-cognate receptors to promote lysogeny
#MicroSky
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
#NatMicroPicks
Been plaguing humans for long! 🦠
Ancient Yersinia pestis strains caused lethal outbreaks as early as 5,500 years ago indicating that plague epidemics occurred before the rise of dense societies.
#MicroSky
www.nature.com/articles/s41...
Been plaguing humans for long! 🦠
Ancient Yersinia pestis strains caused lethal outbreaks as early as 5,500 years ago indicating that plague epidemics occurred before the rise of dense societies.
#MicroSky
www.nature.com/articles/s41...
Lethal plague outbreaks in Lake Baikal hunter-gatherers 5,500 years ago - Nature
Analyses of ancient DNA from hunter-gatherers near Lake Baikal in southeast Siberia around 5,500 years ago indicate that highly virulent Yersinia pestis emerged earlier than previously estimated, far&...
www.nature.com
June 19, 2026 at 12:37 PM
#NatMicroPicks
Been plaguing humans for long! 🦠
Ancient Yersinia pestis strains caused lethal outbreaks as early as 5,500 years ago indicating that plague epidemics occurred before the rise of dense societies.
#MicroSky
www.nature.com/articles/s41...
Been plaguing humans for long! 🦠
Ancient Yersinia pestis strains caused lethal outbreaks as early as 5,500 years ago indicating that plague epidemics occurred before the rise of dense societies.
#MicroSky
www.nature.com/articles/s41...
#NatMicroPicks
GTP-based control of proteome allocation and metabolic flux in bacteria. 🦠
In B. subtilis GTP acts as a key regulator that decouples metabolism from proteome under stress, revealing a distinct resource-allocation strategy
#MicroSky
www.science.org/doi/10.1126/...
GTP-based control of proteome allocation and metabolic flux in bacteria. 🦠
In B. subtilis GTP acts as a key regulator that decouples metabolism from proteome under stress, revealing a distinct resource-allocation strategy
#MicroSky
www.science.org/doi/10.1126/...
Decoupling of global metabolic flux and proteome partitioning in bacteria
Bacteria regulate homeostatic growth by adjusting proteome composition. In Escherichia coli, this coordination is mediated by guanosine tetraphosphate and pentaphosphate, collectively termed (p)ppGpp,...
www.science.org
June 19, 2026 at 12:33 PM
#NatMicroPicks
GTP-based control of proteome allocation and metabolic flux in bacteria. 🦠
In B. subtilis GTP acts as a key regulator that decouples metabolism from proteome under stress, revealing a distinct resource-allocation strategy
#MicroSky
www.science.org/doi/10.1126/...
GTP-based control of proteome allocation and metabolic flux in bacteria. 🦠
In B. subtilis GTP acts as a key regulator that decouples metabolism from proteome under stress, revealing a distinct resource-allocation strategy
#MicroSky
www.science.org/doi/10.1126/...
#NatMicroPicks
A step towards HIV vaccine 💉⚕️
Engineered SHIV infection in macaques successfully induced broadly neutralizing HIV antibodies through a two-step coevolution process, providing insights to guide future vaccine design.
#MicroSky
www.science.org/doi/10.1126/...
A step towards HIV vaccine 💉⚕️
Engineered SHIV infection in macaques successfully induced broadly neutralizing HIV antibodies through a two-step coevolution process, providing insights to guide future vaccine design.
#MicroSky
www.science.org/doi/10.1126/...
Induction of broadly neutralizing HIV antibodies by a two-step mechanism informs vaccine design
A major obstacle confronting HIV-1 vaccine and cure research is the lack of an outbred animal model for rapid and consistent induction of broadly neutralizing antibodies (bNAbs). We designed an epitop...
www.science.org
June 19, 2026 at 12:30 PM
#NatMicroPicks
A step towards HIV vaccine 💉⚕️
Engineered SHIV infection in macaques successfully induced broadly neutralizing HIV antibodies through a two-step coevolution process, providing insights to guide future vaccine design.
#MicroSky
www.science.org/doi/10.1126/...
A step towards HIV vaccine 💉⚕️
Engineered SHIV infection in macaques successfully induced broadly neutralizing HIV antibodies through a two-step coevolution process, providing insights to guide future vaccine design.
#MicroSky
www.science.org/doi/10.1126/...
#NatMicroPicks
A new way to defeat Mycobacterium! 🦠💉
Metabolic overactivation of the L‑histidine biosynthesis pathway in M. tuberculosis impairs its growth and infectivity, revealing a novel bactericidal mechanism for antimycobacterial drug discovery.
#MicroSky
www.nature.com/articles/s41...
A new way to defeat Mycobacterium! 🦠💉
Metabolic overactivation of the L‑histidine biosynthesis pathway in M. tuberculosis impairs its growth and infectivity, revealing a novel bactericidal mechanism for antimycobacterial drug discovery.
#MicroSky
www.nature.com/articles/s41...
Activation of l-histidine biosynthesis as a new antibiotic strategy against Mycobacterium tuberculosis - Nature Communications
Here, the authors report metabolic activation as a potential antimicrobial strategy against Mycobacterium tuberculosis. They show that supra-physiological activation of L-histidine biosynthesis r...
www.nature.com
March 27, 2026 at 4:17 PM
#NatMicroPicks
A new way to defeat Mycobacterium! 🦠💉
Metabolic overactivation of the L‑histidine biosynthesis pathway in M. tuberculosis impairs its growth and infectivity, revealing a novel bactericidal mechanism for antimycobacterial drug discovery.
#MicroSky
www.nature.com/articles/s41...
A new way to defeat Mycobacterium! 🦠💉
Metabolic overactivation of the L‑histidine biosynthesis pathway in M. tuberculosis impairs its growth and infectivity, revealing a novel bactericidal mechanism for antimycobacterial drug discovery.
#MicroSky
www.nature.com/articles/s41...
#NatMicroPicks
Opportunistic Pseudomonas 🦠🌱
Root‑secreted coumarins can be exploited by Pseudomonas NyZ480, whose coumarin‑degrading genes enable opportunistic colonization that worsens plant iron deficiency and impairs overall plant fitness.
#MicroSky
www.nature.com/articles/s41...
Opportunistic Pseudomonas 🦠🌱
Root‑secreted coumarins can be exploited by Pseudomonas NyZ480, whose coumarin‑degrading genes enable opportunistic colonization that worsens plant iron deficiency and impairs overall plant fitness.
#MicroSky
www.nature.com/articles/s41...
Rhizobacteria opportunistically boost colonization and impair plant fitness by degrading plant-derived coumarins under iron deficiency - Nature Communications
Here, the authors show that rhizobacteria can utilize and detoxify simple coumarins secreted by iron-deficient plants, thereby enhancing their root colonization. This, in turn, hampers plant iron acqu...
www.nature.com
March 27, 2026 at 3:31 PM
#NatMicroPicks
Opportunistic Pseudomonas 🦠🌱
Root‑secreted coumarins can be exploited by Pseudomonas NyZ480, whose coumarin‑degrading genes enable opportunistic colonization that worsens plant iron deficiency and impairs overall plant fitness.
#MicroSky
www.nature.com/articles/s41...
Opportunistic Pseudomonas 🦠🌱
Root‑secreted coumarins can be exploited by Pseudomonas NyZ480, whose coumarin‑degrading genes enable opportunistic colonization that worsens plant iron deficiency and impairs overall plant fitness.
#MicroSky
www.nature.com/articles/s41...
#NatMicroPicks
Transmission dynamics of Oropouche virus 🌐
A comprehensive assessment of OROV transmission in 2023-24 epidemic in Manaus City & estimated OROV infections across Latin America and the Caribbean provides better understanding of the OROV burden
#MicroSky
www.nature.com/articles/s41...
Transmission dynamics of Oropouche virus 🌐
A comprehensive assessment of OROV transmission in 2023-24 epidemic in Manaus City & estimated OROV infections across Latin America and the Caribbean provides better understanding of the OROV burden
#MicroSky
www.nature.com/articles/s41...
Transmission dynamics of Oropouche virus in Latin America and the Caribbean - Nature Medicine
The transmission dynamics of the 2023–2024 Oropouche virus (OROV) outbreak in Brazil (Manaus City) revealed a twofold increase in Oropouche seroprevalence in Manaus, and in a separate historical recon...
www.nature.com
March 27, 2026 at 3:23 PM
#NatMicroPicks
Transmission dynamics of Oropouche virus 🌐
A comprehensive assessment of OROV transmission in 2023-24 epidemic in Manaus City & estimated OROV infections across Latin America and the Caribbean provides better understanding of the OROV burden
#MicroSky
www.nature.com/articles/s41...
Transmission dynamics of Oropouche virus 🌐
A comprehensive assessment of OROV transmission in 2023-24 epidemic in Manaus City & estimated OROV infections across Latin America and the Caribbean provides better understanding of the OROV burden
#MicroSky
www.nature.com/articles/s41...
#NatMicroPicks
Diet-microbiome analysis at population scale 💻🦠
Diet shaped gut microbiome composition and function analysed at species-level resolution might enabling long‑term predictions and personalized dietary intervention strategies.
#MicroSky #MicrobiomeSky
www.nature.com/articles/s41...
Diet-microbiome analysis at population scale 💻🦠
Diet shaped gut microbiome composition and function analysed at species-level resolution might enabling long‑term predictions and personalized dietary intervention strategies.
#MicroSky #MicrobiomeSky
www.nature.com/articles/s41...
Diet–microbiome associations in 10,068 individuals from the Human Phenotype Project to guide personalized nutrition - Nature Medicine
Analyses of more than 10,000 participants from the Human Phenotype Project revealed distinct, persistent food–microbiome associations that can be used to simulate personalized dietary interventions to...
www.nature.com
March 27, 2026 at 2:46 PM
#NatMicroPicks
Diet-microbiome analysis at population scale 💻🦠
Diet shaped gut microbiome composition and function analysed at species-level resolution might enabling long‑term predictions and personalized dietary intervention strategies.
#MicroSky #MicrobiomeSky
www.nature.com/articles/s41...
Diet-microbiome analysis at population scale 💻🦠
Diet shaped gut microbiome composition and function analysed at species-level resolution might enabling long‑term predictions and personalized dietary intervention strategies.
#MicroSky #MicrobiomeSky
www.nature.com/articles/s41...
#NatMicroPicks
Microbial factor in cancer immunotherapy resistance 🦀🦠💉
Ligilactobacillus salivarius–derived indole-3-lactic acid suppresses anti-tumor T‑cell populations, driving resistance to anti‑PD‑1 therapy in ESCC
#MicroSky #CancerSky #MicrobiomeSky
www.cell.com/cell-host-mi...
Microbial factor in cancer immunotherapy resistance 🦀🦠💉
Ligilactobacillus salivarius–derived indole-3-lactic acid suppresses anti-tumor T‑cell populations, driving resistance to anti‑PD‑1 therapy in ESCC
#MicroSky #CancerSky #MicrobiomeSky
www.cell.com/cell-host-mi...
Gut microbiota-derived indole-3-lactic acid suppresses anti-PD-1 efficacy in esophageal squamous cell carcinoma
Zhou et al. reveal that gut L. salivarius and its metabolite indole-3-lactic acid
(ILA) drive anti-PD-1 resistance in ESCC. Mechanistically, ILA activates AhR to suppress
NF-κB signaling, triggering t...
www.cell.com
March 27, 2026 at 2:41 PM
#NatMicroPicks
Microbial factor in cancer immunotherapy resistance 🦀🦠💉
Ligilactobacillus salivarius–derived indole-3-lactic acid suppresses anti-tumor T‑cell populations, driving resistance to anti‑PD‑1 therapy in ESCC
#MicroSky #CancerSky #MicrobiomeSky
www.cell.com/cell-host-mi...
Microbial factor in cancer immunotherapy resistance 🦀🦠💉
Ligilactobacillus salivarius–derived indole-3-lactic acid suppresses anti-tumor T‑cell populations, driving resistance to anti‑PD‑1 therapy in ESCC
#MicroSky #CancerSky #MicrobiomeSky
www.cell.com/cell-host-mi...
#NatMicroPicks
Influenza in the sneeze 🤧🦠
A modular sampling tunnel captures, cultures, and sequences virus in human respiratory expulsions, revealing wide individual variation and preserved viral diversity in aerosols.
#MicroSky
www.cell.com/cell/fulltex...
Influenza in the sneeze 🤧🦠
A modular sampling tunnel captures, cultures, and sequences virus in human respiratory expulsions, revealing wide individual variation and preserved viral diversity in aerosols.
#MicroSky
www.cell.com/cell/fulltex...
Controlled human influenza infection reveals heterogeneous expulsion of infectious virus into air
A platform called MIST enables quantification and genotyping of infectious influenza
in expelled respiratory particles, revealing diverse, individual-specific viral loads
and aerosolized variants that...
www.cell.com
March 27, 2026 at 2:38 PM
#NatMicroPicks
Influenza in the sneeze 🤧🦠
A modular sampling tunnel captures, cultures, and sequences virus in human respiratory expulsions, revealing wide individual variation and preserved viral diversity in aerosols.
#MicroSky
www.cell.com/cell/fulltex...
Influenza in the sneeze 🤧🦠
A modular sampling tunnel captures, cultures, and sequences virus in human respiratory expulsions, revealing wide individual variation and preserved viral diversity in aerosols.
#MicroSky
www.cell.com/cell/fulltex...
#NatMicroPicks
Same destination, different routes 🍄🧫🧪
Following 10,000 generations, parallel evolution occurred in separate yeast species, but took different genetic routes driven largely by transcriptomic and trans‑regulatory differences.
#MicroSky
www.nature.com/articles/s41...
Same destination, different routes 🍄🧫🧪
Following 10,000 generations, parallel evolution occurred in separate yeast species, but took different genetic routes driven largely by transcriptomic and trans‑regulatory differences.
#MicroSky
www.nature.com/articles/s41...
Parallel but distinct adaptive routes in the budding and fission yeasts after 10,000 generations of experimental evolution - Nature Ecology & Evolution
Experimental evolution of fission yeast (Schizosaccharomyces pombe) in the same environment as a previous experiment with budding yeast (Saccharomyces cerevisiae) reveals parallel evolution but distin...
www.nature.com
March 20, 2026 at 11:04 AM
#NatMicroPicks
Same destination, different routes 🍄🧫🧪
Following 10,000 generations, parallel evolution occurred in separate yeast species, but took different genetic routes driven largely by transcriptomic and trans‑regulatory differences.
#MicroSky
www.nature.com/articles/s41...
Same destination, different routes 🍄🧫🧪
Following 10,000 generations, parallel evolution occurred in separate yeast species, but took different genetic routes driven largely by transcriptomic and trans‑regulatory differences.
#MicroSky
www.nature.com/articles/s41...
#NatMicroPicks
Vaccination boost! 🦠💉
A delayed booster given 18 months after the initial dose generates a stronger, more diverse, and long‑lasting high‑affinity antibody response to Ebola glycoprotein than a single vaccination.
#MicroSky
www.nature.com/articles/s41...
Vaccination boost! 🦠💉
A delayed booster given 18 months after the initial dose generates a stronger, more diverse, and long‑lasting high‑affinity antibody response to Ebola glycoprotein than a single vaccination.
#MicroSky
www.nature.com/articles/s41...
Improved VSV-Ebola-GP booster vaccination approach promotes antibody affinity maturation and durable anti-Ebola immunity in humans - Nature Immunology
A delayed booster of Ebola vaccine induces a stronger and durable antibody response with higher affinity maturation than a single dose, providing long-lasting immunity and enhancing the ability to pre...
www.nature.com
March 20, 2026 at 11:01 AM
#NatMicroPicks
Vaccination boost! 🦠💉
A delayed booster given 18 months after the initial dose generates a stronger, more diverse, and long‑lasting high‑affinity antibody response to Ebola glycoprotein than a single vaccination.
#MicroSky
www.nature.com/articles/s41...
Vaccination boost! 🦠💉
A delayed booster given 18 months after the initial dose generates a stronger, more diverse, and long‑lasting high‑affinity antibody response to Ebola glycoprotein than a single vaccination.
#MicroSky
www.nature.com/articles/s41...
#NatMicroPicks
Host-microbe cycle in chronic kidney disease 🦠⚕️
Inefficient removal of indole derivatives due to kidney dysfunction in mice raises the levels of nitrate that in turn promote indole producing E. coli
#MicroSky
www.science.org/doi/10.1126/...
Host-microbe cycle in chronic kidney disease 🦠⚕️
Inefficient removal of indole derivatives due to kidney dysfunction in mice raises the levels of nitrate that in turn promote indole producing E. coli
#MicroSky
www.science.org/doi/10.1126/...
Host-derived nitrate fuels indole production by Escherichia coli to drive chronic kidney disease progression
Chronic kidney disease (CKD) is linked to an elevated fecal abundance of Enterobacteriaceae, but the ecological drivers of this shift and its impact on disease progression remain unclear. The uremic t...
www.science.org
March 20, 2026 at 10:58 AM
#NatMicroPicks
Host-microbe cycle in chronic kidney disease 🦠⚕️
Inefficient removal of indole derivatives due to kidney dysfunction in mice raises the levels of nitrate that in turn promote indole producing E. coli
#MicroSky
www.science.org/doi/10.1126/...
Host-microbe cycle in chronic kidney disease 🦠⚕️
Inefficient removal of indole derivatives due to kidney dysfunction in mice raises the levels of nitrate that in turn promote indole producing E. coli
#MicroSky
www.science.org/doi/10.1126/...
#NatMicroPicks
Live biotherapeutics for bacterial vaginosis 🚺🦠
A short course of vaginal Lactobacillus crispatus biotherapeutics after antibiotics safely achieved sustained colonization in many women recovering from bacterial vaginosis.
#MicroSky
www.cell.com/cell-host-mi...
Live biotherapeutics for bacterial vaginosis 🚺🦠
A short course of vaginal Lactobacillus crispatus biotherapeutics after antibiotics safely achieved sustained colonization in many women recovering from bacterial vaginosis.
#MicroSky
www.cell.com/cell-host-mi...
VIBRANT: A phase 1 randomized trial of multi-strain vaginal L. crispatus live biotherapeutic products in people with bacterial vaginosis
In this phase 1 randomized trial of women with bacterial vaginosis in South Africa and the United States, Potloane et al. show that a multi-strain vaginal Lactobacillus crispatus live biotherapeutic administered for just 3–7 days following antibiotics can achieve vaginal colonization lasting up to 12 weeks.
www.cell.com
March 20, 2026 at 10:29 AM
#NatMicroPicks
Live biotherapeutics for bacterial vaginosis 🚺🦠
A short course of vaginal Lactobacillus crispatus biotherapeutics after antibiotics safely achieved sustained colonization in many women recovering from bacterial vaginosis.
#MicroSky
www.cell.com/cell-host-mi...
Live biotherapeutics for bacterial vaginosis 🚺🦠
A short course of vaginal Lactobacillus crispatus biotherapeutics after antibiotics safely achieved sustained colonization in many women recovering from bacterial vaginosis.
#MicroSky
www.cell.com/cell-host-mi...
#NatMicroPicks
From trash to treasure 🦠🔧♻️
Engineered E. coli convert the plastic PET to levodopa - a frontline medication for Parkinson’s disease.
#MicroSky
www.nature.com/articles/s41...
From trash to treasure 🦠🔧♻️
Engineered E. coli convert the plastic PET to levodopa - a frontline medication for Parkinson’s disease.
#MicroSky
www.nature.com/articles/s41...
Microbial upcycling of plastic waste to levodopa - Nature Sustainability
The production of high-value chemicals can involve energy-intensive processes, necessitating sustainable production strategies. Here the authors present a circular bioeconomy approach, upcycling plast...
www.nature.com
March 20, 2026 at 10:19 AM
#NatMicroPicks
From trash to treasure 🦠🔧♻️
Engineered E. coli convert the plastic PET to levodopa - a frontline medication for Parkinson’s disease.
#MicroSky
www.nature.com/articles/s41...
From trash to treasure 🦠🔧♻️
Engineered E. coli convert the plastic PET to levodopa - a frontline medication for Parkinson’s disease.
#MicroSky
www.nature.com/articles/s41...
#NatMicroPicks
Engineered E. coli boosts tumour immunotherapy 🦠🔧💉
A synthetic arginine–nitric oxide (NO) circuit enables sustained intratumoral NO production that promotes vascular normalization and immune reprogramming in mouse models
#MicroSky
www.nature.com/articles/s41...
Engineered E. coli boosts tumour immunotherapy 🦠🔧💉
A synthetic arginine–nitric oxide (NO) circuit enables sustained intratumoral NO production that promotes vascular normalization and immune reprogramming in mouse models
#MicroSky
www.nature.com/articles/s41...
An engineered E. coli strain sustains intratumoral nitric oxide production to boost effectiveness of tumor immunotherapy - Nature Biotechnology
An engineered Escherichia coli Nissle 1917 strain carrying a synthetic arginine–nitric oxide (NO) circuit enables sustained intratumoral NO production that promotes vascular normalization and immune r...
www.nature.com
March 20, 2026 at 10:15 AM
#NatMicroPicks
Engineered E. coli boosts tumour immunotherapy 🦠🔧💉
A synthetic arginine–nitric oxide (NO) circuit enables sustained intratumoral NO production that promotes vascular normalization and immune reprogramming in mouse models
#MicroSky
www.nature.com/articles/s41...
Engineered E. coli boosts tumour immunotherapy 🦠🔧💉
A synthetic arginine–nitric oxide (NO) circuit enables sustained intratumoral NO production that promotes vascular normalization and immune reprogramming in mouse models
#MicroSky
www.nature.com/articles/s41...
#NatMicroPicks
Sending evolution into overdrive 🔧🦠
A Φ29‑based DNA replication system in E. coli enables stable and targeted hypermutation achieving evolution of enzyme activities within days
#MicroSky
www.nature.com/articles/s41...
Sending evolution into overdrive 🔧🦠
A Φ29‑based DNA replication system in E. coli enables stable and targeted hypermutation achieving evolution of enzyme activities within days
#MicroSky
www.nature.com/articles/s41...
Highly mutagenic continuous evolution in E. coli using a Φ29-based orthogonal replication system - Nature Biotechnology
Mutational rates of bacterial evolution are increased using an error-prone orthogonal system.
www.nature.com
March 13, 2026 at 12:39 PM
#NatMicroPicks
Sending evolution into overdrive 🔧🦠
A Φ29‑based DNA replication system in E. coli enables stable and targeted hypermutation achieving evolution of enzyme activities within days
#MicroSky
www.nature.com/articles/s41...
Sending evolution into overdrive 🔧🦠
A Φ29‑based DNA replication system in E. coli enables stable and targeted hypermutation achieving evolution of enzyme activities within days
#MicroSky
www.nature.com/articles/s41...
#NatMicroPicks
No-GMO enhanced Bt toxin 🦠🌱🪲
Naturally occurring 'sporesilk' matrix coating the Bacillus thuringiensis toxin crystals boosts insecticidal activity providing a non-GMO pest biocontrol.
#MicroSky
www.nature.com/articles/s41...
No-GMO enhanced Bt toxin 🦠🌱🪲
Naturally occurring 'sporesilk' matrix coating the Bacillus thuringiensis toxin crystals boosts insecticidal activity providing a non-GMO pest biocontrol.
#MicroSky
www.nature.com/articles/s41...
Auto-crosslinking sporesilk fibers promote endospore and Cry toxin clustering - Nature Communications
Authors reveal that protein nanofibrils govern assembly of bacterial spores and extrasporal toxins into insecticidal aggregates. Spores and parasporal bodies are incased in a “sporesilk” matrix that d...
www.nature.com
March 13, 2026 at 12:36 PM
#NatMicroPicks
No-GMO enhanced Bt toxin 🦠🌱🪲
Naturally occurring 'sporesilk' matrix coating the Bacillus thuringiensis toxin crystals boosts insecticidal activity providing a non-GMO pest biocontrol.
#MicroSky
www.nature.com/articles/s41...
No-GMO enhanced Bt toxin 🦠🌱🪲
Naturally occurring 'sporesilk' matrix coating the Bacillus thuringiensis toxin crystals boosts insecticidal activity providing a non-GMO pest biocontrol.
#MicroSky
www.nature.com/articles/s41...
#NatMicroPicks
The versatile Acinetobacter baumannii! 🦠
The dreaded pathogen naturally occupies soil and airborne niches that underpin its recalcitrance and human contact may have shaped its evolution.
#MicroSky
www.nature.com/articles/s41...
The versatile Acinetobacter baumannii! 🦠
The dreaded pathogen naturally occupies soil and airborne niches that underpin its recalcitrance and human contact may have shaped its evolution.
#MicroSky
www.nature.com/articles/s41...
Acinetobacter baumannii’s lifestyle includes soil-dwelling colonization of decaying plant material and airborne spread - Nature Communications
Little is known about the ecology and evolution of the nosocomial pathogen Acinetobacter baumannii outside the hospital. Here, Wilharm et al. show that the lifestyle of A. baumannii includes soil-dwel...
www.nature.com
March 13, 2026 at 12:27 PM
#NatMicroPicks
The versatile Acinetobacter baumannii! 🦠
The dreaded pathogen naturally occupies soil and airborne niches that underpin its recalcitrance and human contact may have shaped its evolution.
#MicroSky
www.nature.com/articles/s41...
The versatile Acinetobacter baumannii! 🦠
The dreaded pathogen naturally occupies soil and airborne niches that underpin its recalcitrance and human contact may have shaped its evolution.
#MicroSky
www.nature.com/articles/s41...
#NatMicroPicks
Multi-kingdom microbial interplay in cancer 🦠🍄🦀⚕️
Candida albicans synergizes with Fusobacterium nucleatum in colorectal cancer offering a potential therapeutic target via L‑arginine disruption.
#MicroSky #CancerSky
www.cell.com/cancer-cell/...
Multi-kingdom microbial interplay in cancer 🦠🍄🦀⚕️
Candida albicans synergizes with Fusobacterium nucleatum in colorectal cancer offering a potential therapeutic target via L‑arginine disruption.
#MicroSky #CancerSky
www.cell.com/cancer-cell/...
Candida albicans synergizes with Fusobacterium nucleatum in colorectal cancer progression via the Flo9-RadD interaction
How does other types of microbe like fungi influence tumor-promoting role of Fusobacterium
nucleatum? In this study, Li et al. establish that commensal fungi facilitate translocation
of pro-tumor bact...
www.cell.com
March 13, 2026 at 12:17 PM
#NatMicroPicks
Multi-kingdom microbial interplay in cancer 🦠🍄🦀⚕️
Candida albicans synergizes with Fusobacterium nucleatum in colorectal cancer offering a potential therapeutic target via L‑arginine disruption.
#MicroSky #CancerSky
www.cell.com/cancer-cell/...
Multi-kingdom microbial interplay in cancer 🦠🍄🦀⚕️
Candida albicans synergizes with Fusobacterium nucleatum in colorectal cancer offering a potential therapeutic target via L‑arginine disruption.
#MicroSky #CancerSky
www.cell.com/cancer-cell/...
#NatMicroPicks
Antibiotics in the long run ⌛💊🦠
Antibiotic use shows lasting associations with reduced gut microbial diversity for up to 8 years, indicating long-term impacts on the adult gut microbiome.
#MicroSky #MicrobiomeSky
www.nature.com/articles/s41...
Antibiotics in the long run ⌛💊🦠
Antibiotic use shows lasting associations with reduced gut microbial diversity for up to 8 years, indicating long-term impacts on the adult gut microbiome.
#MicroSky #MicrobiomeSky
www.nature.com/articles/s41...
Antibiotic use and gut microbiome composition links from individual-level prescription data of 14,979 individuals - Nature Medicine
Using individual-level data from the Swedish Prescribed Drug Register and fecal metagenomes of 14,979 individuals in Sweden, the authors examined the association between oral antibiotic use over 8 yea...
www.nature.com
March 13, 2026 at 12:14 PM
#NatMicroPicks
Antibiotics in the long run ⌛💊🦠
Antibiotic use shows lasting associations with reduced gut microbial diversity for up to 8 years, indicating long-term impacts on the adult gut microbiome.
#MicroSky #MicrobiomeSky
www.nature.com/articles/s41...
Antibiotics in the long run ⌛💊🦠
Antibiotic use shows lasting associations with reduced gut microbial diversity for up to 8 years, indicating long-term impacts on the adult gut microbiome.
#MicroSky #MicrobiomeSky
www.nature.com/articles/s41...