New from CIDRAP & @NEJMEvidence
Public Health Alerts: Paenibacillus dendritiformis as a cause of destructive meningitis in infants
One infected premature infant was still not able to eat by mouth, sit unsupported, or roll over at 8 months of age
www.cidrap.umn.edu/p...
Public Health Alerts: Paenibacillus dendritiformis as a cause of destructive meningitis in infants
One infected premature infant was still not able to eat by mouth, sit unsupported, or roll over at 8 months of age
www.cidrap.umn.edu/p...
February 3, 2026 at 8:23 PM
New from CIDRAP & @NEJMEvidence
Public Health Alerts: Paenibacillus dendritiformis as a cause of destructive meningitis in infants
One infected premature infant was still not able to eat by mouth, sit unsupported, or roll over at 8 months of age
www.cidrap.umn.edu/p...
Public Health Alerts: Paenibacillus dendritiformis as a cause of destructive meningitis in infants
One infected premature infant was still not able to eat by mouth, sit unsupported, or roll over at 8 months of age
www.cidrap.umn.edu/p...
Which Patients with Heart Failure Benefit from an SGLT2 Inhibitor?
evidence.nejm.org/doi/full/10....
@nejm.org
#CardioSky #MedSky #NejmEvidence #HeartFailure #SGLT2i #Flozin
evidence.nejm.org/doi/full/10....
@nejm.org
#CardioSky #MedSky #NejmEvidence #HeartFailure #SGLT2i #Flozin
July 22, 2025 at 2:20 PM
Which Patients with Heart Failure Benefit from an SGLT2 Inhibitor?
evidence.nejm.org/doi/full/10....
@nejm.org
#CardioSky #MedSky #NejmEvidence #HeartFailure #SGLT2i #Flozin
evidence.nejm.org/doi/full/10....
@nejm.org
#CardioSky #MedSky #NejmEvidence #HeartFailure #SGLT2i #Flozin
Cardiopulmonary Exercise Testing.
evidence.nejm.org/doi/full/10....
@nejm.org
#NejmEvidence #CardioSky #MedSky #Cardiology #CPET
#ReviewArticle
evidence.nejm.org/doi/full/10....
@nejm.org
#NejmEvidence #CardioSky #MedSky #Cardiology #CPET
#ReviewArticle
January 28, 2025 at 3:11 PM
Cardiopulmonary Exercise Testing.
evidence.nejm.org/doi/full/10....
@nejm.org
#NejmEvidence #CardioSky #MedSky #Cardiology #CPET
#ReviewArticle
evidence.nejm.org/doi/full/10....
@nejm.org
#NejmEvidence #CardioSky #MedSky #Cardiology #CPET
#ReviewArticle
What a great honour to contribute to this piece on the evidence and the implementation considerations for ERAS and look to ERAS's future potential
with Gregg Nelson and Kevin Elias for @nejm.org NEJMEvidence
evidence.nejm.org/doi/full/10....
with Gregg Nelson and Kevin Elias for @nejm.org NEJMEvidence
evidence.nejm.org/doi/full/10....
Enhanced Recovery after Surgery — Evidence and Practice
Enhanced Recovery After Surgery (ERAS) is a global initiative comprised of a series
of evidence-based interventions in the preoperative, intraoperative, and postoperative
surgical phases. When impl...
evidence.nejm.org
February 25, 2025 at 4:00 PM
What a great honour to contribute to this piece on the evidence and the implementation considerations for ERAS and look to ERAS's future potential
with Gregg Nelson and Kevin Elias for @nejm.org NEJMEvidence
evidence.nejm.org/doi/full/10....
with Gregg Nelson and Kevin Elias for @nejm.org NEJMEvidence
evidence.nejm.org/doi/full/10....
Here is our June 2025 #PICUJournalWatch collection! picujournalwatch.com/journalwatch.... Topics inc. enteral nutrition, PICU survival & CPR. AOTM: REDvent - an RCT on lung and diaphragm protection
picujournalwatch.com/journalwatch... in @NEJMEvidence. Enjoy!
@picujournalwatch.bsky.social
picujournalwatch.com/journalwatch... in @NEJMEvidence. Enjoy!
@picujournalwatch.bsky.social
picujournalwatch.com
July 8, 2025 at 1:58 AM
Here is our June 2025 #PICUJournalWatch collection! picujournalwatch.com/journalwatch.... Topics inc. enteral nutrition, PICU survival & CPR. AOTM: REDvent - an RCT on lung and diaphragm protection
picujournalwatch.com/journalwatch... in @NEJMEvidence. Enjoy!
@picujournalwatch.bsky.social
picujournalwatch.com/journalwatch... in @NEJMEvidence. Enjoy!
@picujournalwatch.bsky.social
🆕in @NEJMEvidence: CP3's @TimAndersonMD & coauthors discuss what "tomorrow's trial" of inpatient BP management should look like & challenges in conducting it.
evidence.nejm.org/doi/full/10....
@pittgim.bsky.social @pittdeptofmed.bsky.social
evidence.nejm.org/doi/full/10....
@pittgim.bsky.social @pittdeptofmed.bsky.social
December 5, 2024 at 5:56 PM
🆕in @NEJMEvidence: CP3's @TimAndersonMD & coauthors discuss what "tomorrow's trial" of inpatient BP management should look like & challenges in conducting it.
evidence.nejm.org/doi/full/10....
@pittgim.bsky.social @pittdeptofmed.bsky.social
evidence.nejm.org/doi/full/10....
@pittgim.bsky.social @pittdeptofmed.bsky.social
Estamos muy orgullosas(os) de presentar los resultados de un estudio colaborativo publicado en @NEJMEvidence que evalúa la posibilidad de #ulipristal en lugar de #mifepristona en un régimen combinado con #misoprostol para #abortoconmedicamentos evidence.nejm.org/doi/full/10....
A Proof-of-Concept Study of Ulipristal Acetate for Early Medication Abortion
The current regimen for early medication abortion in many countries is mifepristone and misoprostol, but mifepristone is relatively expensive and limited in many regions. Ulipristal acetate, with a...
evidence.nejm.org
May 15, 2025 at 2:43 PM
Estamos muy orgullosas(os) de presentar los resultados de un estudio colaborativo publicado en @NEJMEvidence que evalúa la posibilidad de #ulipristal en lugar de #mifepristona en un régimen combinado con #misoprostol para #abortoconmedicamentos evidence.nejm.org/doi/full/10....
NEJM Evidence
@NEJMEvidence
“… the investigators found a relationship between diastolic blood pressure and stroke, despite the fact that the study population could be considered low risk.” 📈 Read the editorial by Drs. @sarah_gorey and @JaneALeopold
: eviden.cc/3Z0GUgL
@NEJMEvidence
“… the investigators found a relationship between diastolic blood pressure and stroke, despite the fact that the study population could be considered low risk.” 📈 Read the editorial by Drs. @sarah_gorey and @JaneALeopold
: eviden.cc/3Z0GUgL
January 14, 2025 at 1:42 AM
NEJM Evidence
@NEJMEvidence
“… the investigators found a relationship between diastolic blood pressure and stroke, despite the fact that the study population could be considered low risk.” 📈 Read the editorial by Drs. @sarah_gorey and @JaneALeopold
: eviden.cc/3Z0GUgL
@NEJMEvidence
“… the investigators found a relationship between diastolic blood pressure and stroke, despite the fact that the study population could be considered low risk.” 📈 Read the editorial by Drs. @sarah_gorey and @JaneALeopold
: eviden.cc/3Z0GUgL
We're proud to present the results from a collaborative study assessing the possibility of #ulipristal instead of #mifepristone in a combined regimen with #misoprostol for #medicationabortion. @OPTinnovate. Article published in @NEJMEvidence -- evidence.nejm.org/doi/full/10....
A Proof-of-Concept Study of Ulipristal Acetate for Early Medication Abortion
The current regimen for early medication abortion in many countries is mifepristone and misoprostol, but mifepristone is relatively expensive and limited in many regions. Ulipristal acetate, with a...
evidence.nejm.org
May 15, 2025 at 2:43 PM
We're proud to present the results from a collaborative study assessing the possibility of #ulipristal instead of #mifepristone in a combined regimen with #misoprostol for #medicationabortion. @OPTinnovate. Article published in @NEJMEvidence -- evidence.nejm.org/doi/full/10....
Blood pressure targets for vasodilatory shock: IPD-MA @NEJMevidence
3 RCTs with 3352 pts
RR for 90-day mortality associated with a lower blood pressure target was 0.93 (95% CrI, 0.76 to 1.07; low certainty, posterior probability of benefit 87%).
evidence.nejm.org/doi/full/10....
3 RCTs with 3352 pts
RR for 90-day mortality associated with a lower blood pressure target was 0.93 (95% CrI, 0.76 to 1.07; low certainty, posterior probability of benefit 87%).
evidence.nejm.org/doi/full/10....
Blood Pressure Targets for Adults with Vasodilatory Shock — An Individual Patient Data Meta-Analysis
We sought to estimate whether a lower mean arterial blood pressure target, compared
with a higher mean arterial blood pressure target, reduced 90-day all-cause mortality
among critically ill adult ...
evidence.nejm.org
November 20, 2024 at 4:06 AM
Blood pressure targets for vasodilatory shock: IPD-MA @NEJMevidence
3 RCTs with 3352 pts
RR for 90-day mortality associated with a lower blood pressure target was 0.93 (95% CrI, 0.76 to 1.07; low certainty, posterior probability of benefit 87%).
evidence.nejm.org/doi/full/10....
3 RCTs with 3352 pts
RR for 90-day mortality associated with a lower blood pressure target was 0.93 (95% CrI, 0.76 to 1.07; low certainty, posterior probability of benefit 87%).
evidence.nejm.org/doi/full/10....
x.com/erictopol/st... @angushervey.com @fixthenews.com.web.brid.gy @progressntwrk.bsky.social @freethink.com
Eric Topol on X: "How to detect a single case of measles in a population of >1 million people? Wastewater sequencing picked it up from 0.000005% of ~1 billion sequencing reads! https://t.co/TT33Cpeog6 @NEJMEvidence https://t.co/FNwMBz2rHJ" / X
How to detect a single case of measles in a population of >1 million people? Wastewater sequencing picked it up from 0.000005% of ~1 billion sequencing reads! https://t.co/TT33Cpeog6 @NEJMEvidence https://t.co/FNwMBz2rHJ
x.com
May 2, 2026 at 12:44 PM
x.com
x.com
December 24, 2024 at 10:47 AM
It turns out the assumptions required to adopt typically used natural experiments to inform specific clinical scenarios (as opposed to typical health policy questions) are quite strong.
#HealthPolicy #NaturalExperiments #ClinicalResearch #NEJMEvidence
#HealthPolicy #NaturalExperiments #ClinicalResearch #NEJMEvidence
April 29, 2025 at 12:43 PM
It turns out the assumptions required to adopt typically used natural experiments to inform specific clinical scenarios (as opposed to typical health policy questions) are quite strong.
#HealthPolicy #NaturalExperiments #ClinicalResearch #NEJMEvidence
#HealthPolicy #NaturalExperiments #ClinicalResearch #NEJMEvidence
https://evidence.nejm.org/pb-assets/evidence-site/content/EVIDoa2100021-1636059484090.pdf Prescribed Water Intake in Autosomal Dominant
Polycystic Kidney Disease @NEJMEvidence - new journal
Polycystic Kidney Disease @NEJMEvidence - new journal
December 11, 2024 at 2:22 AM
https://evidence.nejm.org/pb-assets/evidence-site/content/EVIDoa2100021-1636059484090.pdf Prescribed Water Intake in Autosomal Dominant
Polycystic Kidney Disease @NEJMEvidence - new journal
Polycystic Kidney Disease @NEJMEvidence - new journal
May 2023 issue @KidneyNews - do we need to rethink the overcorrection of hyponatremia? @NephroMD and Stern http://onlinedigeditions.com/publication/?m=15191&i=790744&p=14&ver=html5 on a controversial editorial on a reject paper in @NEJMEvidence...
403 Forbidden
onlinedigeditions.com
December 9, 2024 at 10:39 PM
May 2023 issue @KidneyNews - do we need to rethink the overcorrection of hyponatremia? @NephroMD and Stern http://onlinedigeditions.com/publication/?m=15191&i=790744&p=14&ver=html5 on a controversial editorial on a reject paper in @NEJMEvidence...
NEJM Evidence
@NEJMEvidence
Original Article: “Adolescent Blood Pressure and Early Age Stroke” by B. Fishman et al.: eviden.cc/3YJ36f2
#Cardiology
@NEJMEvidence
Original Article: “Adolescent Blood Pressure and Early Age Stroke” by B. Fishman et al.: eviden.cc/3YJ36f2
#Cardiology
January 9, 2025 at 12:51 AM
NEJM Evidence
@NEJMEvidence
Original Article: “Adolescent Blood Pressure and Early Age Stroke” by B. Fishman et al.: eviden.cc/3YJ36f2
#Cardiology
@NEJMEvidence
Original Article: “Adolescent Blood Pressure and Early Age Stroke” by B. Fishman et al.: eviden.cc/3YJ36f2
#Cardiology
TET2 mutations → ↑ cytopenia risk (HR=1.19)
Spliceosome genes (SF3B1, SRSF2) → ↑↑ risk (HR=1.93)
TP53 pathway → ↑ risk (HR=1.28)
IDH1/2 mutations → ↑↑ risk (HR=2.24)
Building on @LDWeeks_MD @NEJMEvidence
work on CHIP risk prediction!
Spliceosome genes (SF3B1, SRSF2) → ↑↑ risk (HR=1.93)
TP53 pathway → ↑ risk (HR=1.28)
IDH1/2 mutations → ↑↑ risk (HR=2.24)
Building on @LDWeeks_MD @NEJMEvidence
work on CHIP risk prediction!
et.al
June 5, 2025 at 12:52 AM
TET2 mutations → ↑ cytopenia risk (HR=1.19)
Spliceosome genes (SF3B1, SRSF2) → ↑↑ risk (HR=1.93)
TP53 pathway → ↑ risk (HR=1.28)
IDH1/2 mutations → ↑↑ risk (HR=2.24)
Building on @LDWeeks_MD @NEJMEvidence
work on CHIP risk prediction!
Spliceosome genes (SF3B1, SRSF2) → ↑↑ risk (HR=1.93)
TP53 pathway → ↑ risk (HR=1.28)
IDH1/2 mutations → ↑↑ risk (HR=2.24)
Building on @LDWeeks_MD @NEJMEvidence
work on CHIP risk prediction!