#OMM12
Bet that when you woke up this morning you thought "you know what would be nice? A review of #microbiome research performed with #OMM12 mice" 🐀

Well, have we got some good news for you

The latest paper from the BBH lab was published TODAY 🚨

www.tandfonline.com/doi/full/10....
The OMM12 mice: a decade of dissecting host-microbiome interactions
Humans and their associated microbes form a multifaceted ecosystem. Gaining mechanistic insight into this system necessitates reductionist models integrating ecological and immunological dimensions...
www.tandfonline.com
September 23, 2026 at 9:43 AM
Uwe now switches to a stable 10-member course gut community (from OMM12 strains) and the influence of different polymers

and back to marine systems and chitin particles (spatial restrictions) through the PNAS paper of @sammy-pontrelli.bsky.social
www.pnas.org/doi/10.1073/...

#MibiNet
Hypersensitivity of chitin degradation to initial species densities due to monomer diffusion | PNAS
Resource competition strongly shapes microbial community dynamics and functionality. In polysaccharide-degrading communities, primary degraders rel...
www.pnas.org
September 30, 2026 at 12:48 PM
Munich researchers found that mice colonized with a 12-strain microbial community (OMM12) showed stronger Th1 immune responses and cleared LCMV virus more effectively, but suffered worse disease than mice with a typical or no microbiome

www.nature.com/articles/s41...
A specific microbial consortium enhances Th1 immunity, improves LCMV viral clearance but aggravates LCMV disease pathology in mice - Nature Communications
How gut microbiota affect systemic responses to viral infection is still unclear. Here the authors use LCMV mouse infection model to show that a low complexity 12-strains community but not germ-free c...
www.nature.com
April 25, 2025 at 2:53 PM