#OncoDailyGI
We described the role of ecDNA in pancreatic cancer. Thank you to all the people and funding involved @natureportfolio.nature.com @BottonChamp @vincorbo @AIRC @PrecodeP @Valsecchifdn @ItalianPCC @OncoDailyGI @OncoAlert
www.nature.com/articles/s41...
MYC ecDNA promotes intratumour heterogeneity and plasticity in PDAC - Nature
In a model of pancreatic ductal adenocarcinoma, extrachromosomal DNAs are shown to be a source of high-level focal amplification driving MYC heterogeneity and phenotypic adaptation.
www.nature.com
March 13, 2025 at 9:10 AM