Orthohantavirus sinnombreense
Mammarenavirus lassaense
Mammarenavirus juninense
Mammarenavirus lujoense
Orthoebolavirus zairense
Orthoflavivirus zikaense
Orthoflavivirus denguei
Orthoflavivirus nilense
Henipavirus nipahense
Phlebovirus riftense
You just can't make this s*** up. You really can't.
Mammarenavirus lassaense
Mammarenavirus juninense
Mammarenavirus lujoense
Orthoebolavirus zairense
Orthoflavivirus zikaense
Orthoflavivirus denguei
Orthoflavivirus nilense
Henipavirus nipahense
Phlebovirus riftense
You just can't make this s*** up. You really can't.
July 31, 2024 at 3:56 AM
Orthohantavirus sinnombreense
Mammarenavirus lassaense
Mammarenavirus juninense
Mammarenavirus lujoense
Orthoebolavirus zairense
Orthoflavivirus zikaense
Orthoflavivirus denguei
Orthoflavivirus nilense
Henipavirus nipahense
Phlebovirus riftense
You just can't make this s*** up. You really can't.
Mammarenavirus lassaense
Mammarenavirus juninense
Mammarenavirus lujoense
Orthoebolavirus zairense
Orthoflavivirus zikaense
Orthoflavivirus denguei
Orthoflavivirus nilense
Henipavirus nipahense
Phlebovirus riftense
You just can't make this s*** up. You really can't.
Two new reports on T cells and viral infections
—the ability to prevent without neutralizing antibodies
www.nature.com/articles/s41...
—more Tregs and enhanced protection via multiple Covid booster shots
www.biorxiv.org/content/10.1...
—the ability to prevent without neutralizing antibodies
www.nature.com/articles/s41...
—more Tregs and enhanced protection via multiple Covid booster shots
www.biorxiv.org/content/10.1...
Vaccine-induced T cell responses control Orthoflavivirus challenge infection without neutralizing antibodies in humans - Nature Microbiology
The authors demonstrate the effectiveness of T cells in controlling acute viral infections, without neutralizing antibodies, by conducting an Orthoflavivirus vaccination and challenge study in humans.
www.nature.com
January 10, 2025 at 6:33 PM
Two new reports on T cells and viral infections
—the ability to prevent without neutralizing antibodies
www.nature.com/articles/s41...
—more Tregs and enhanced protection via multiple Covid booster shots
www.biorxiv.org/content/10.1...
—the ability to prevent without neutralizing antibodies
www.nature.com/articles/s41...
—more Tregs and enhanced protection via multiple Covid booster shots
www.biorxiv.org/content/10.1...
Immunologists have discovered that vaccine-induced T cells—white blood cells that destroy pathogens—can completely prevent viral infection to an extent previously unknown until now. These vax-prompted Tcells prevent infection w/out a 1st wave of neutralizing antibodies www.nature.com/articles/s41...
Vaccine-induced T cell responses control Orthoflavivirus challenge infection without neutralizing antibodies in humans - Nature Microbiology
The authors demonstrate the effectiveness of T cells in controlling acute viral infections, without neutralizing antibodies, by conducting an Orthoflavivirus vaccination and challenge study in humans.
www.nature.com
January 12, 2025 at 11:10 AM
Immunologists have discovered that vaccine-induced T cells—white blood cells that destroy pathogens—can completely prevent viral infection to an extent previously unknown until now. These vax-prompted Tcells prevent infection w/out a 1st wave of neutralizing antibodies www.nature.com/articles/s41...
ICYMI: Vaccine-induced T cell responses control Orthoflavivirus challenge infection without neutralizing antibodies in humans
by Eng Eong Ooi & co
www.nature.com/articles/s41...
by Eng Eong Ooi & co
www.nature.com/articles/s41...
Vaccine-induced T cell responses control Orthoflavivirus challenge infection without neutralizing antibodies in humans - Nature Microbiology
The authors demonstrate the effectiveness of T cells in controlling acute viral infections, without neutralizing antibodies, by conducting an Orthoflavivirus vaccination and challenge study in humans.
www.nature.com
January 30, 2025 at 9:09 AM
ICYMI: Vaccine-induced T cell responses control Orthoflavivirus challenge infection without neutralizing antibodies in humans
by Eng Eong Ooi & co
www.nature.com/articles/s41...
by Eng Eong Ooi & co
www.nature.com/articles/s41...
A CRISPR activation screen identifies SPART as a pan-orthoflavivirus restriction factor
@cp-cellhostmicrobe.bsky.social
www.cell.com/cell-host-mi...
@cp-cellhostmicrobe.bsky.social
www.cell.com/cell-host-mi...
May 19, 2026 at 8:38 PM
A CRISPR activation screen identifies SPART as a pan-orthoflavivirus restriction factor
@cp-cellhostmicrobe.bsky.social
www.cell.com/cell-host-mi...
@cp-cellhostmicrobe.bsky.social
www.cell.com/cell-host-mi...
📣 New WastewaterSCAN publication: West Nile Virus (Orthoflavivirus nilense) RNA concentrations in wastewater solids at five wastewater treatment plants in the United States 🛟🧪
Read more: peerj.com/articles/197...
Read more: peerj.com/articles/197...
West Nile Virus (Orthoflavivirus nilense) RNA concentrations in wastewater solids at five wastewater treatment plants in the United States
Background Orthoflavivirus nilense, formerly known as West Nile Virus (WNV), has become endemic to the United States since its introduction in 1999. Current surveillance methods rely primarily on mosq...
peerj.com
July 23, 2025 at 6:06 PM
📣 New WastewaterSCAN publication: West Nile Virus (Orthoflavivirus nilense) RNA concentrations in wastewater solids at five wastewater treatment plants in the United States 🛟🧪
Read more: peerj.com/articles/197...
Read more: peerj.com/articles/197...
Exploitation of host U2AF1 and U2AF2 splicing factors facilitates mosquito-borne orthoflavivirus infection across species academic.oup.com/nar/article/...
Exploitation of host U2AF1 and U2AF2 splicing factors facilitates mosquito-borne orthoflavivirus infection across species
Abstract. To identify novel host factors essential for orthoflavivirus replication, we performed proteomic profiling of endoplasmic reticulum fractions iso
academic.oup.com
July 19, 2026 at 2:38 AM
Exploitation of host U2AF1 and U2AF2 splicing factors facilitates mosquito-borne orthoflavivirus infection across species academic.oup.com/nar/article/...
#Orthoflavivirus survey in Rio Grande do Sul revealed African lineage #ZIKV circulating in NHPs, with infection confirmed in Alouatta guariba, underscoring complex #ViralEcology. #medsky #Virology
#Zoonoses #OpenAccess: doi.org/10.15212/ZOO...
#Zoonoses #OpenAccess: doi.org/10.15212/ZOO...
October 2, 2026 at 2:40 PM
#Orthoflavivirus survey in Rio Grande do Sul revealed African lineage #ZIKV circulating in NHPs, with infection confirmed in Alouatta guariba, underscoring complex #ViralEcology. #medsky #Virology
#Zoonoses #OpenAccess: doi.org/10.15212/ZOO...
#Zoonoses #OpenAccess: doi.org/10.15212/ZOO...
New insights into an old vaccine: potency and breadth of neutralizing antibodies elicited by the yellow fever vaccine 17D are boosted by heterologous Orthoflavivirus infection
✅ Just Accepted
🔗 https://bit.ly/4l9Iyr1
✅ Just Accepted
🔗 https://bit.ly/4l9Iyr1
March 1, 2026 at 12:33 AM
New insights into an old vaccine: potency and breadth of neutralizing antibodies elicited by the yellow fever vaccine 17D are boosted by heterologous Orthoflavivirus infection
✅ Just Accepted
🔗 https://bit.ly/4l9Iyr1
✅ Just Accepted
🔗 https://bit.ly/4l9Iyr1
Another new preprint! This time looking at flavivirus NS5 interactions with our collaborator Armando Arias - www.biorxiv.org/content/10.6...
Mitophagy-related prohibitin 2 is an orthoflavivirus restriction factor targeted for degradation during infection
Mitophagy selectively removes depolarised and damaged mitochondria, promoting cell viability. Some members of the Orthoflavivirus genus activate mitophagy to allow extended replication times in a surv...
www.biorxiv.org
December 6, 2025 at 11:21 AM
Another new preprint! This time looking at flavivirus NS5 interactions with our collaborator Armando Arias - www.biorxiv.org/content/10.6...
New work preprinted from the Daniels Lab!
SIRT1 remodels astrocyte metabolism and promotes viral replication during neurotropic orthoflavivirus infection
Orthoflaviviruses depend on host metabolic resources to replicate, but how distinct cell types in the central nervous system (CNS) alter their metabolism in response to infection remains incompletely ...
www.biorxiv.org
August 1, 2026 at 1:56 PM
New work preprinted from the Daniels Lab!
Viral-name-change-drama
HIV-1 -> Lentivirus humimdef1
SARS-CoV-2-> Betacoronavirus pandemicum
West Nile Virus -> Orthoflavivirus nilense
HIV-1 -> Lentivirus humimdef1
SARS-CoV-2-> Betacoronavirus pandemicum
West Nile Virus -> Orthoflavivirus nilense
‘Silly and pompous’: Official new names for viruses rile up researchers
An overhaul of viruses’ scientific naming system has incensed some virologists, but others are more accepting
www.science.org
December 15, 2024 at 1:20 PM
Viral-name-change-drama
HIV-1 -> Lentivirus humimdef1
SARS-CoV-2-> Betacoronavirus pandemicum
West Nile Virus -> Orthoflavivirus nilense
HIV-1 -> Lentivirus humimdef1
SARS-CoV-2-> Betacoronavirus pandemicum
West Nile Virus -> Orthoflavivirus nilense
Potency of nucleoside analogs against Powassan virus replication and identification of 4'-fluorouridine as a therapeutic candidate for tick-borne orthoflavivirus encephalitis https://www.biorxiv.org/content/10.64898/2026.09.24.754293v1
September 26, 2026 at 6:16 AM
Potency of nucleoside analogs against Powassan virus replication and identification of 4'-fluorouridine as a therapeutic candidate for tick-borne orthoflavivirus encephalitis https://www.biorxiv.org/content/10.64898/2026.09.24.754293v1
*flertando*
O HCV pertence a família dos flavivirus (Flaviviridae), junto com a dengue e a febre amarela. Recentemente, os vírus que pertencem ao gênero "Flavivirus" e que estavam na família Flaviviridae foram renomeados para orthoflavivirus, para evitar confusão taxonômica entre gênero e família.
O HCV pertence a família dos flavivirus (Flaviviridae), junto com a dengue e a febre amarela. Recentemente, os vírus que pertencem ao gênero "Flavivirus" e que estavam na família Flaviviridae foram renomeados para orthoflavivirus, para evitar confusão taxonômica entre gênero e família.
*flertando*
a transformada de Fourier serve pra decompor uma onda em componentes de frequência, basta convolver a resposta ao impulso com a função alvo, com base na assinatura de frequência você pode comprimir a onda original fazendo uma quantização, ou computar uma assinatura sonora pra reconhecim
a transformada de Fourier serve pra decompor uma onda em componentes de frequência, basta convolver a resposta ao impulso com a função alvo, com base na assinatura de frequência você pode comprimir a onda original fazendo uma quantização, ou computar uma assinatura sonora pra reconhecim
May 25, 2026 at 8:37 PM
*flertando*
O HCV pertence a família dos flavivirus (Flaviviridae), junto com a dengue e a febre amarela. Recentemente, os vírus que pertencem ao gênero "Flavivirus" e que estavam na família Flaviviridae foram renomeados para orthoflavivirus, para evitar confusão taxonômica entre gênero e família.
O HCV pertence a família dos flavivirus (Flaviviridae), junto com a dengue e a febre amarela. Recentemente, os vírus que pertencem ao gênero "Flavivirus" e que estavam na família Flaviviridae foram renomeados para orthoflavivirus, para evitar confusão taxonômica entre gênero e família.
SPART, a pan-orthoflavivirus restriction factor
CRISPR activation screen IDs SPART as broadly restricting orthoflaviviruses by altering localization of ITCH. ITCH mediates capsid ubiquitination, triggering its degradation & release of viral RNA
www.cell.com/cell-host-mi...
CRISPR activation screen IDs SPART as broadly restricting orthoflaviviruses by altering localization of ITCH. ITCH mediates capsid ubiquitination, triggering its degradation & release of viral RNA
www.cell.com/cell-host-mi...
A CRISPR activation screen identifies SPART as a pan-orthoflavivirus restriction factor
Li et al. demonstrate that the host protein SPART broadly restricts orthoflavivirus
infections by modulating the localization of ITCH. ITCH plays critical roles in orthoflavivirus
infection by mediati...
www.cell.com
May 22, 2026 at 2:14 PM
SPART, a pan-orthoflavivirus restriction factor
CRISPR activation screen IDs SPART as broadly restricting orthoflaviviruses by altering localization of ITCH. ITCH mediates capsid ubiquitination, triggering its degradation & release of viral RNA
www.cell.com/cell-host-mi...
CRISPR activation screen IDs SPART as broadly restricting orthoflaviviruses by altering localization of ITCH. ITCH mediates capsid ubiquitination, triggering its degradation & release of viral RNA
www.cell.com/cell-host-mi...
WastewaterSCAN research demonstrates that #WestNileVirus (WNV) RNA can be detected in #wastewater samples during viral circulation within a community, after measuring WNV RNA concentrations in over 600 samples collected from 5 wastewater treatment plants. 🛟🧪
Check it out: peerj.com/articles/197...
Check it out: peerj.com/articles/197...
West Nile Virus (Orthoflavivirus nilense) RNA concentrations in wastewater solids at five wastewater treatment plants in the United States
Background Orthoflavivirus nilense, formerly known as West Nile Virus (WNV), has become endemic to the United States since its introduction in 1999. Current surveillance methods rely primarily on mosq...
peerj.com
July 29, 2025 at 9:30 PM
WastewaterSCAN research demonstrates that #WestNileVirus (WNV) RNA can be detected in #wastewater samples during viral circulation within a community, after measuring WNV RNA concentrations in over 600 samples collected from 5 wastewater treatment plants. 🛟🧪
Check it out: peerj.com/articles/197...
Check it out: peerj.com/articles/197...
Here are some of the other other new 'latinized' names:
HIV-1: Lentivirus humimdef1
West Nile virus: Orthoflavivirus nilense
Shark River virus: Orthobunyavirus squalofluvii
🧪
HIV-1: Lentivirus humimdef1
West Nile virus: Orthoflavivirus nilense
Shark River virus: Orthobunyavirus squalofluvii
🧪
December 13, 2024 at 6:48 PM
Here are some of the other other new 'latinized' names:
HIV-1: Lentivirus humimdef1
West Nile virus: Orthoflavivirus nilense
Shark River virus: Orthobunyavirus squalofluvii
🧪
HIV-1: Lentivirus humimdef1
West Nile virus: Orthoflavivirus nilense
Shark River virus: Orthobunyavirus squalofluvii
🧪
Vaccine-induced T cell responses control Orthoflavivirus challenge infection without neutralizing antibodies in humans
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Vaccine-induced T cell responses control Orthoflavivirus challenge infection without neutralizing antibodies in humans - Nature Microbiology
The authors demonstrate the effectiveness of T cells in controlling acute viral infections, without neutralizing antibodies, by conducting an Orthoflavivirus vaccination and challenge study in humans.
www.nature.com
January 10, 2025 at 5:32 PM
Vaccine-induced T cell responses control Orthoflavivirus challenge infection without neutralizing antibodies in humans
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Delighted to see Marielena Saivish's manuscript on the "Standardization of Quantitative Plaque-Based Viral Assays for Orthoflavivirus Cacipacoré" published. A collaborative effort with colleagues on our drive to characterize Brazilian neglected orthoflaviviruses. #UTMBHealth #FAMERP #FAPESP #SBV
October 10, 2025 at 12:58 PM
Delighted to see Marielena Saivish's manuscript on the "Standardization of Quantitative Plaque-Based Viral Assays for Orthoflavivirus Cacipacoré" published. A collaborative effort with colleagues on our drive to characterize Brazilian neglected orthoflaviviruses. #UTMBHealth #FAMERP #FAPESP #SBV
A genus-wide interaction atlas across NS4B orthologues identifies a conserved role for UFMylation in orthoflavivirus replication https://www.biorxiv.org/content/10.1101/2025.05.15.653649v1
May 16, 2025 at 4:16 AM
A genus-wide interaction atlas across NS4B orthologues identifies a conserved role for UFMylation in orthoflavivirus replication https://www.biorxiv.org/content/10.1101/2025.05.15.653649v1
Fil très intéressant (comme toujours...).
(un détail : en anglais le nom du virus est West Nile)
Deux compléments : Usutu, un autre virus proche (Orthoflavivirus, comme West Nile, avec le même vecteur Culex) mais peu zoonotique est en expansion dans les populations d'oiseaux en Europe.
(un détail : en anglais le nom du virus est West Nile)
Deux compléments : Usutu, un autre virus proche (Orthoflavivirus, comme West Nile, avec le même vecteur Culex) mais peu zoonotique est en expansion dans les populations d'oiseaux en Europe.
September 30, 2025 at 11:46 AM
Fil très intéressant (comme toujours...).
(un détail : en anglais le nom du virus est West Nile)
Deux compléments : Usutu, un autre virus proche (Orthoflavivirus, comme West Nile, avec le même vecteur Culex) mais peu zoonotique est en expansion dans les populations d'oiseaux en Europe.
(un détail : en anglais le nom du virus est West Nile)
Deux compléments : Usutu, un autre virus proche (Orthoflavivirus, comme West Nile, avec le même vecteur Culex) mais peu zoonotique est en expansion dans les populations d'oiseaux en Europe.
Our EU-funded project REFINE has finally kicked off! Super proud to be part of this inspiring initiative with great scientists from across Europe and Australia. We aim to address the escalating challenge of mosquito-borne orthoflavivirus infections.
www.refine-project.org/news/refine-...
#EU #HADEA
www.refine-project.org/news/refine-...
#EU #HADEA
REFINE Launch event – REFINE
www.refine-project.org
March 18, 2025 at 4:30 PM
Our EU-funded project REFINE has finally kicked off! Super proud to be part of this inspiring initiative with great scientists from across Europe and Australia. We aim to address the escalating challenge of mosquito-borne orthoflavivirus infections.
www.refine-project.org/news/refine-...
#EU #HADEA
www.refine-project.org/news/refine-...
#EU #HADEA
Japanese encephalitis virus in Australia.
Japanese encephalitis virus (JEV) in Australia – a 2022 study and the current state
A brief overview of a report describing the 2022 discovery of Japanese encephalitis virus (JEV) in Australia. This was the first local outbreak in southern Australia and set the stage for an ongoing virus presence. Some JEV backstory JEV is a virus belonging to the species Orthoflavivirus japonicum. Infection was rare in Australia but is a leading cause of childhood viral encephalitis in Asia.
virologydownunder.com
January 29, 2025 at 6:43 AM
Japanese encephalitis virus in Australia.