Damage-induced pyroptosis drives endogenous thymic regeneration by activating the purinergic receptor P2Y2
www.nature.com/articles/s41...
@dudakov-lab.bsky.social @fredhutch.org
www.nature.com/articles/s41...
@dudakov-lab.bsky.social @fredhutch.org
January 4, 2026 at 7:43 PM
Damage-induced pyroptosis drives endogenous thymic regeneration by activating the purinergic receptor P2Y2
www.nature.com/articles/s41...
@dudakov-lab.bsky.social @fredhutch.org
www.nature.com/articles/s41...
@dudakov-lab.bsky.social @fredhutch.org
Happy to share the current version of our latest story, currently under peer review. Cool collab with @dablab.bsky.social @manickam-lab.bsky.social and others. We are not only understanding endothelial deficits in an #autism model, but now also capable of rescuing them! #16p11.2 #treatment #P2Y2
Purinergic receptor activation rectifies autism-associated endothelial dysfunction
Early cerebrovascular alterations affect brain maturation by impacting trophic support and energy supply. Recent evidence in a 16p11.2 deletion mouse model of autism spectrum disorder (ASD) revealed b...
www.biorxiv.org
June 3, 2025 at 8:33 AM
Happy to share the current version of our latest story, currently under peer review. Cool collab with @dablab.bsky.social @manickam-lab.bsky.social and others. We are not only understanding endothelial deficits in an #autism model, but now also capable of rescuing them! #16p11.2 #treatment #P2Y2
Sagar Joshi, Lance Davidson and team find that supracellular contractility in Xenopus embryo epithelia is regulated by extracellular ATP and the purinergic receptor P2Y2.
Highlight: journals.biologists.com/jcs/article/...
Article: journals.biologists.com/jcs/article/...
#OpenAccess #ReadandPublish
Highlight: journals.biologists.com/jcs/article/...
Article: journals.biologists.com/jcs/article/...
#OpenAccess #ReadandPublish
October 7, 2025 at 9:45 AM
Sagar Joshi, Lance Davidson and team find that supracellular contractility in Xenopus embryo epithelia is regulated by extracellular ATP and the purinergic receptor P2Y2.
Highlight: journals.biologists.com/jcs/article/...
Article: journals.biologists.com/jcs/article/...
#OpenAccess #ReadandPublish
Highlight: journals.biologists.com/jcs/article/...
Article: journals.biologists.com/jcs/article/...
#OpenAccess #ReadandPublish
Sûrement! Vous pourriez jaser de récepteurs P2Y2 pis toute. 🤣
August 31, 2023 at 10:06 AM
Sûrement! Vous pourriez jaser de récepteurs P2Y2 pis toute. 🤣
P2Y2 purinergic receptor and DNA sensor cGAS dictate ionizing radiation-mediated proinflammatory macrophage activation https://www.biorxiv.org/content/10.1101/2024.12.19.629560v1
December 22, 2024 at 8:16 PM
P2Y2 purinergic receptor and DNA sensor cGAS dictate ionizing radiation-mediated proinflammatory macrophage activation https://www.biorxiv.org/content/10.1101/2024.12.19.629560v1
RRIDs were included in this International Journal of Molecular Sciences paper. We value the author's support of reproducibility. #ReproducibleResearch #STMpublishing #STMpublishing
Disruption of P2Y2 Signaling Promotes Breast Tumor Cell Dissemination by Reducing ATP-Dependent Calcium Elevation and Actin Localization to Cell Junctions
doi.org
May 28, 2025 at 7:00 AM
RRIDs were included in this International Journal of Molecular Sciences paper. We value the author's support of reproducibility. #ReproducibleResearch #STMpublishing #STMpublishing
Does Tesla stock still deserve to be valued at a premium derived from CEO Elon Musk's leadership? #elon #musk #elonmusk
https://mu.sk/P2y2
https://mu.sk/P2y2
September 18, 2026 at 12:02 PM
Does Tesla stock still deserve to be valued at a premium derived from CEO Elon Musk's leadership? #elon #musk #elonmusk
https://mu.sk/P2y2
https://mu.sk/P2y2
RRID:AB_1074620 from @thermofishersci.bsky.social was used by authors in their The FASEB Journal paper. Thanks for making your methods matter! #RRID #accelerateopenscience #reproducibility
Purinergic Receptor P2Y2 Regulates Neurogenesis and Functional Recovery Following Spinal Cord Injury in Zebrafish
Read the full paper: Purinergic Receptor P2Y2 Regulates Neurogenesis and Functional Recovery Following Spinal Cord Injury in Zebrafish
doi.org
September 16, 2026 at 7:34 PM
RRID:AB_1074620 from @thermofishersci.bsky.social was used by authors in their The FASEB Journal paper. Thanks for making your methods matter! #RRID #accelerateopenscience #reproducibility
Bora Reviver os tempos de Lan House? LIVE 20h: www.youtube.com/watch?v=p2Y2...
INACREDITÁVEL!!! Simulador de LAN HOUSE Brasileira dos anos 2000 - Brazilian Lan House 2003
YouTube video by A Vida o Universo e Video Games
www.youtube.com
September 13, 2026 at 6:21 PM
Bora Reviver os tempos de Lan House? LIVE 20h: www.youtube.com/watch?v=p2Y2...
The authors included RRIDs in their in Journal of Immunology Research paper! Thanks for making your methods matter! #BetterScience #RRID #OpenResearch
P2Y2 Receptor Controls TLR3-Induced Chemokine Production in Intestinal Epithelial Cells
Read the full paper: P2Y2 Receptor Controls TLR3-Induced Chemokine Production in Intestinal Epithelial Cells
doi.org
September 2, 2026 at 7:01 AM
The authors included RRIDs in their in Journal of Immunology Research paper! Thanks for making your methods matter! #BetterScience #RRID #OpenResearch
A recent review published in Molecular and Digital Medicine provides an overview of the purinergic receptor P2Y2 and its involvement in cancer-related processes. Discover the study: https://www.keaipublishing.com/en/news/the-emerging-roles-of-p2y2-receptor-signaling-in-cancer-biology/
August 19, 2026 at 10:00 AM
A recent review published in Molecular and Digital Medicine provides an overview of the purinergic receptor P2Y2 and its involvement in cancer-related processes. Discover the study: https://www.keaipublishing.com/en/news/the-emerging-roles-of-p2y2-receptor-signaling-in-cancer-biology/
Hitting lung cancer where it hurts
This article frames the discovery as a direct panacea, suggesting that targeting EGFR activity alongside P2Y2 disruption is immediately actionable for NSCLC treatment. However, the leap from demonstrating protein destabilization in vitro to developing safe, sy…
This article frames the discovery as a direct panacea, suggesting that targeting EGFR activity alongside P2Y2 disruption is immediately actionable for NSCLC treatment. However, the leap from demonstrating protein destabilization in vitro to developing safe, sy…
arc-codex.com
July 31, 2026 at 3:34 AM
Hitting lung cancer where it hurts
This article frames the discovery as a direct panacea, suggesting that targeting EGFR activity alongside P2Y2 disruption is immediately actionable for NSCLC treatment. However, the leap from demonstrating protein destabilization in vitro to developing safe, sy…
This article frames the discovery as a direct panacea, suggesting that targeting EGFR activity alongside P2Y2 disruption is immediately actionable for NSCLC treatment. However, the leap from demonstrating protein destabilization in vitro to developing safe, sy…
Ancien militaire sur la BA 105, cycliste émérite, Serge Bontemps a été maire de Saint-Sébastien-de-Morsent durant deux mandats.
▶️ https://l.actu.fr/p2y2
▶️ https://l.actu.fr/p2y2
March 24, 2026 at 7:52 PM
Ancien militaire sur la BA 105, cycliste émérite, Serge Bontemps a été maire de Saint-Sébastien-de-Morsent durant deux mandats.
▶️ https://l.actu.fr/p2y2
▶️ https://l.actu.fr/p2y2
It was a Little Black Duck... but Google refuses that search.. www.youtube.com/watch?v=p2Y2...
4032. The Burl Ives Story 7. The Little White Duck (Barrows and Zaritzky) South Yarra Senior Centre
YouTube video by raymondcrooke
www.youtube.com
February 13, 2025 at 2:35 AM
It was a Little Black Duck... but Google refuses that search.. www.youtube.com/watch?v=p2Y2...
#Warsaw #Warszawa Dramatyczne sceny pod Warszawą. "Poszkodowana leżała obok składu" https://wars.aw/P2y2
March 24, 2026 at 5:58 PM
#Warsaw #Warszawa Dramatyczne sceny pod Warszawą. "Poszkodowana leżała obok składu" https://wars.aw/P2y2
A genome-wide genetic screen reveals the P2Y2-integrin axis as a stabilizer of EGFR mutants in non–small cell lung cancer (NSCLC)
Science Advances
www.science.org/doi/10.1126/...
Science Advances
www.science.org/doi/10.1126/...
A genome-wide genetic screen reveals the P2Y2-integrin axis as a stabilizer of EGFR mutants in non–small cell lung cancer (NSCLC)
The ATP, P2Y2, and integrin signaling axis helps EGFR mutants survive in lung cancer, pointing to a target to tackle resistance.
www.science.org
January 22, 2026 at 12:06 AM
A genome-wide genetic screen reveals the P2Y2-integrin axis as a stabilizer of EGFR mutants in non–small cell lung cancer (NSCLC)
Science Advances
www.science.org/doi/10.1126/...
Science Advances
www.science.org/doi/10.1126/...
#TechRadar It's the perfect time to try Visible Wireless – this deal gets you the best cheap unlimited plan for just $22.50/mo https://techrad.ar/P2y2 #NetworkProviders #Phones
October 9, 2025 at 2:38 PM
#TechRadar It's the perfect time to try Visible Wireless – this deal gets you the best cheap unlimited plan for just $22.50/mo https://techrad.ar/P2y2 #NetworkProviders #Phones
Feed: "GEN – Genetic Engineering and Biotechnology News"
By: John Sterling on Friday, January 23, 2026
By: John Sterling on Friday, January 23, 2026
Lung Cancer’s “Bodyguard System” Discovered by Singapore Scientists
When the team knocked out the P2Y2 receptor in drug-resistant cancer cells, it led to an almost complete loss of the mutant EGFR protein.
www.genengnews.com
January 24, 2026 at 2:27 PM
Feed: "GEN – Genetic Engineering and Biotechnology News"
By: John Sterling on Friday, January 23, 2026
By: John Sterling on Friday, January 23, 2026
A genome-wide genetic screen reveals the P2Y2-integrin axis as a stabilizer of EGFR mutants in non–small cell lung cancer (NSCLC)
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
A genome-wide genetic screen reveals the P2Y2-integrin axis as a stabilizer of EGFR mutants in non–small cell lung cancer (NSCLC)
The ATP, P2Y2, and integrin signaling axis helps EGFR mutants survive in lung cancer, pointing to a target to tackle resistance.
www.science.org
January 25, 2026 at 6:17 PM
A genome-wide genetic screen reveals the P2Y2-integrin axis as a stabilizer of EGFR mutants in non–small cell lung cancer (NSCLC)
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Supracellular contractility in Xenopus laevis embryonic epithelia regulated by extracellular nucleotides and the purinergic G-protein coupled receptor P2Y2. https://www.biorxiv.org/content/10.1101/2025.01.21.634176v1
January 23, 2025 at 10:34 AM
Supracellular contractility in Xenopus laevis embryonic epithelia regulated by extracellular nucleotides and the purinergic G-protein coupled receptor P2Y2. https://www.biorxiv.org/content/10.1101/2025.01.21.634176v1
P2Y2 receptors are essential for hepatic clearance ofuropathogenic E. coli in a murine sepsis model https://www.biorxiv.org/content/10.1101/2025.06.10.658777v1
June 15, 2025 at 3:01 AM
P2Y2 receptors are essential for hepatic clearance ofuropathogenic E. coli in a murine sepsis model https://www.biorxiv.org/content/10.1101/2025.06.10.658777v1
P2Y2 receptors are essential for hepatic clearance ofuropathogenic E. coli in a murine sepsis model https://www.biorxiv.org/content/10.1101/2025.06.10.658777v1
June 15, 2025 at 3:01 AM
P2Y2 receptors are essential for hepatic clearance ofuropathogenic E. coli in a murine sepsis model https://www.biorxiv.org/content/10.1101/2025.06.10.658777v1
P2Y2 purinergic receptor and DNA sensor cGAS dictate ionizing radiation-mediated proinflammatory macrophage activation https://www.biorxiv.org/content/10.1101/2024.12.19.629560v1
December 22, 2024 at 8:16 PM
P2Y2 purinergic receptor and DNA sensor cGAS dictate ionizing radiation-mediated proinflammatory macrophage activation https://www.biorxiv.org/content/10.1101/2024.12.19.629560v1