Targeting PFIC Disease Mechanism: New Approach Focuses on Restoring Bile Acid Transport
7 October 2026 (Navroze Bureau) Progressive familial intrahepatic cholestasis, or PFIC, is a rare inherited liver disorder that primarily affects children and can lead to progressive liver damage. Researchers…
7 October 2026 (Navroze Bureau) Progressive familial intrahepatic cholestasis, or PFIC, is a rare inherited liver disorder that primarily affects children and can lead to progressive liver damage. Researchers…
Targeting PFIC Disease Mechanism: New Approach Focuses on Restoring Bile Acid Transport
7 October 2026 (Navroze Bureau) Progressive familial intrahepatic cholestasis, or PFIC, is a rare inherited liver disorder that primarily affects children and can lead to progressive liver damage. Researchers are increasingly focusing on treatments that address the underlying biological mechanisms of the disease rather than only managing symptoms. Hisamitsu Hayashi, PhD, associate professor at the University of Tokyo Graduate School of Pharmaceutical Sciences, has been involved in research examining the role of bile salt export pump, or BSEP, in PFIC and how existing medicines could potentially be used to restore its function.
navroze.in
October 7, 2026 at 4:10 AM
Targeting PFIC Disease Mechanism: New Approach Focuses on Restoring Bile Acid Transport
7 October 2026 (Navroze Bureau) Progressive familial intrahepatic cholestasis, or PFIC, is a rare inherited liver disorder that primarily affects children and can lead to progressive liver damage. Researchers…
7 October 2026 (Navroze Bureau) Progressive familial intrahepatic cholestasis, or PFIC, is a rare inherited liver disorder that primarily affects children and can lead to progressive liver damage. Researchers…
Targeting PFIC Disease Mechanism: New Approach Focuses on Restoring Bile Acid Transport
7 October 2026 Punjab Khabarnama Bureau : Progressive familial intrahepatic cholestasis, or PFIC, is a rare inherited liver disorder that primarily affects children and can lead to progressive liver damage.…
7 October 2026 Punjab Khabarnama Bureau : Progressive familial intrahepatic cholestasis, or PFIC, is a rare inherited liver disorder that primarily affects children and can lead to progressive liver damage.…
Targeting PFIC Disease Mechanism: New Approach Focuses on Restoring Bile Acid Transport
7 October 2026 Punjab Khabarnama Bureau : Progressive familial intrahepatic cholestasis, or PFIC, is a rare inherited liver disorder that primarily affects children and can lead to progressive liver damage. Researchers are increasingly focusing on treatments that address the underlying biological mechanisms of the disease rather than only managing symptoms. Hisamitsu Hayashi, PhD, associate professor at the University of Tokyo Graduate School of Pharmaceutical Sciences, has been involved in research examining the role of bile salt export pump, or BSEP, in PFIC and how existing medicines could potentially be used to restore its function.
punjabkhabarnama.com
October 7, 2026 at 3:36 AM
Targeting PFIC Disease Mechanism: New Approach Focuses on Restoring Bile Acid Transport
7 October 2026 Punjab Khabarnama Bureau : Progressive familial intrahepatic cholestasis, or PFIC, is a rare inherited liver disorder that primarily affects children and can lead to progressive liver damage.…
7 October 2026 Punjab Khabarnama Bureau : Progressive familial intrahepatic cholestasis, or PFIC, is a rare inherited liver disorder that primarily affects children and can lead to progressive liver damage.…
Goodnight, Bluesky!
This YouTube channel is playing LoFi tunes with a Christmas flair
Probably the only thing I'll listen to for the next month 😂😂
www.youtube.com/watch?v=pfiC...
This YouTube channel is playing LoFi tunes with a Christmas flair
Probably the only thing I'll listen to for the next month 😂😂
www.youtube.com/watch?v=pfiC...
christmas lofi radio 🎄cozy beats to get festive to
YouTube video by Lofi Girl
www.youtube.com
November 22, 2024 at 5:07 AM
Goodnight, Bluesky!
This YouTube channel is playing LoFi tunes with a Christmas flair
Probably the only thing I'll listen to for the next month 😂😂
www.youtube.com/watch?v=pfiC...
This YouTube channel is playing LoFi tunes with a Christmas flair
Probably the only thing I'll listen to for the next month 😂😂
www.youtube.com/watch?v=pfiC...
Parents often become powerful advocates when navigating Progressive Familial Intrahepatic Cholestasis (PFIC).
This PFIC Awareness Day, we're proud to share family perspectives and support PFIC Network, one of ESPGHAN's partnered Patient & Parent Organisations.
Learn more: www.pfic.org/
#ESPGHAN
This PFIC Awareness Day, we're proud to share family perspectives and support PFIC Network, one of ESPGHAN's partnered Patient & Parent Organisations.
Learn more: www.pfic.org/
#ESPGHAN
October 7, 2026 at 11:03 AM
Parents often become powerful advocates when navigating Progressive Familial Intrahepatic Cholestasis (PFIC).
This PFIC Awareness Day, we're proud to share family perspectives and support PFIC Network, one of ESPGHAN's partnered Patient & Parent Organisations.
Learn more: www.pfic.org/
#ESPGHAN
This PFIC Awareness Day, we're proud to share family perspectives and support PFIC Network, one of ESPGHAN's partnered Patient & Parent Organisations.
Learn more: www.pfic.org/
#ESPGHAN
I usually don't promote my music here that often, but my lofi music made it into the LOFI GIRL Christmas Radio! 🎄
This was made in collab with the amazing Moon-uh ♥
Full track here: t.co/5Yimev48RV
LOFI GIRL Christmas Radio: www.youtube.com/watch?v=pfiC...
This was made in collab with the amazing Moon-uh ♥
Full track here: t.co/5Yimev48RV
LOFI GIRL Christmas Radio: www.youtube.com/watch?v=pfiC...
November 18, 2024 at 5:23 PM
I usually don't promote my music here that often, but my lofi music made it into the LOFI GIRL Christmas Radio! 🎄
This was made in collab with the amazing Moon-uh ♥
Full track here: t.co/5Yimev48RV
LOFI GIRL Christmas Radio: www.youtube.com/watch?v=pfiC...
This was made in collab with the amazing Moon-uh ♥
Full track here: t.co/5Yimev48RV
LOFI GIRL Christmas Radio: www.youtube.com/watch?v=pfiC...
Today is #PFICAwarenessDay.
🤝 We are proud to partner with PFIC Network to amplify the voices and experiences of those affected👩⚕️
Learn more about Progressive Familial Intrahepatic Cholestasis (PFIC) and how you can support this important awareness initiative through PFIC Network 🔗 www.pfic.org/
🤝 We are proud to partner with PFIC Network to amplify the voices and experiences of those affected👩⚕️
Learn more about Progressive Familial Intrahepatic Cholestasis (PFIC) and how you can support this important awareness initiative through PFIC Network 🔗 www.pfic.org/
October 5, 2026 at 1:01 PM
Today is #PFICAwarenessDay.
🤝 We are proud to partner with PFIC Network to amplify the voices and experiences of those affected👩⚕️
Learn more about Progressive Familial Intrahepatic Cholestasis (PFIC) and how you can support this important awareness initiative through PFIC Network 🔗 www.pfic.org/
🤝 We are proud to partner with PFIC Network to amplify the voices and experiences of those affected👩⚕️
Learn more about Progressive Familial Intrahepatic Cholestasis (PFIC) and how you can support this important awareness initiative through PFIC Network 🔗 www.pfic.org/
For children with Progressive Familial Intrahepatic Cholestasis (PFIC), diagnosis is more than identifying a rare disease. It is the first step towards personalised care.
Learn more through PFIC Network, one of ESPGHAN's partner Patient & Parent Organisations 👉 www.pfic.org/
#ESPGHAN #PFIC
Learn more through PFIC Network, one of ESPGHAN's partner Patient & Parent Organisations 👉 www.pfic.org/
#ESPGHAN #PFIC
October 4, 2026 at 6:01 PM
For children with Progressive Familial Intrahepatic Cholestasis (PFIC), diagnosis is more than identifying a rare disease. It is the first step towards personalised care.
Learn more through PFIC Network, one of ESPGHAN's partner Patient & Parent Organisations 👉 www.pfic.org/
#ESPGHAN #PFIC
Learn more through PFIC Network, one of ESPGHAN's partner Patient & Parent Organisations 👉 www.pfic.org/
#ESPGHAN #PFIC
Although my US dual citizenship still fucks me with that country's fuckass extraterritorial special boy rules, so I have to do somewhat baroque dances with e.g. a bunch of cash-secured puts because of PFIC bullshit
June 30, 2026 at 7:45 PM
Although my US dual citizenship still fucks me with that country's fuckass extraterritorial special boy rules, so I have to do somewhat baroque dances with e.g. a bunch of cash-secured puts because of PFIC bullshit
New treatment for rare genetic liver disorder approved in Japan: Active ingredient in existing drug provides much-needed new treatment option for people with PFIC types 1 & 2. Read here: www.u-tokyo.ac.jp/focus/en/pre...
#UTokyo #Research #PFIC #Liver #Cholestasis #LiverDisorder
#UTokyo #Research #PFIC #Liver #Cholestasis #LiverDisorder
New treatment for rare genetic liver disorder approved in Japan | The University of Tokyo
Giving to UTokyo
www.u-tokyo.ac.jp
September 16, 2026 at 10:00 AM
New treatment for rare genetic liver disorder approved in Japan: Active ingredient in existing drug provides much-needed new treatment option for people with PFIC types 1 & 2. Read here: www.u-tokyo.ac.jp/focus/en/pre...
#UTokyo #Research #PFIC #Liver #Cholestasis #LiverDisorder
#UTokyo #Research #PFIC #Liver #Cholestasis #LiverDisorder
christmas lofi radio 🎄cozy beats to get festive to
YouTube video by Lofi Girl
www.youtube.com
November 19, 2024 at 12:06 AM
www.irs.gov/instructions... iDeCoのアロケーションが外国株式100%とかだとPFICに該当するが、それがiDeCoである場合Form 8621に書かなくて良い (そのPFICのshareholder扱いにならない) というのはこの辺か
February 22, 2024 at 5:38 AM
www.irs.gov/instructions... iDeCoのアロケーションが外国株式100%とかだとPFICに該当するが、それがiDeCoである場合Form 8621に書かなくて良い (そのPFICのshareholder扱いにならない) というのはこの辺か
PFIC is a rare genetic liver condition affecting 1 in 50,000 to 1 in 100,000 people. You'll find clear and trusted information on its causes, symptoms, treatment and where to find support here https://ow.ly/lcnb50ZUoV9 #PFICAwarenessDay
October 5, 2026 at 11:30 AM
PFIC is a rare genetic liver condition affecting 1 in 50,000 to 1 in 100,000 people. You'll find clear and trusted information on its causes, symptoms, treatment and where to find support here https://ow.ly/lcnb50ZUoV9 #PFICAwarenessDay
Late 8621 Filing with IRS Streamlined Penalty Relief
Form 8621 is required by the IRS when a U.S. taxpayer owns shares in a Passive Foreign Investment Company (PFIC). A PFIC is generally a foreign corporation where: At least 75% of its income is considered passive (e.g., dividends, interest,…
Form 8621 is required by the IRS when a U.S. taxpayer owns shares in a Passive Foreign Investment Company (PFIC). A PFIC is generally a foreign corporation where: At least 75% of its income is considered passive (e.g., dividends, interest,…
Late 8621 Filing with IRS Streamlined Penalty Relief
Form 8621 is required by the IRS when a U.S. taxpayer owns shares in a Passive Foreign Investment Company (PFIC). A PFIC is generally a foreign corporation where: At least 75% of its income is considered passive (e.g., dividends, interest, rents, capital gains), orAt least 50% of its assets are held for producing passive income. Most foreign mutual funds, ETFs, and pooled investment funds are treated as PFICs under U.S.
expertaccountingservicesllc.com
October 2, 2025 at 11:03 PM
Late 8621 Filing with IRS Streamlined Penalty Relief
Form 8621 is required by the IRS when a U.S. taxpayer owns shares in a Passive Foreign Investment Company (PFIC). A PFIC is generally a foreign corporation where: At least 75% of its income is considered passive (e.g., dividends, interest,…
Form 8621 is required by the IRS when a U.S. taxpayer owns shares in a Passive Foreign Investment Company (PFIC). A PFIC is generally a foreign corporation where: At least 75% of its income is considered passive (e.g., dividends, interest,…
christmas lofi radio 🎄cozy beats to get festive to
YouTube video by Lofi Girl
www.youtube.com
December 24, 2024 at 9:14 PM
what people think Americans abroad think about: "I wonder if I'll start saying 'lift' instead of 'elevator' at some point"
what we actually think about: "yikes. Congress needs to add an exception to the Securities Act of 1933 and fix PFIC taxation"
what we actually think about: "yikes. Congress needs to add an exception to the Securities Act of 1933 and fix PFIC taxation"
January 5, 2025 at 11:30 AM
what people think Americans abroad think about: "I wonder if I'll start saying 'lift' instead of 'elevator' at some point"
what we actually think about: "yikes. Congress needs to add an exception to the Securities Act of 1933 and fix PFIC taxation"
what we actually think about: "yikes. Congress needs to add an exception to the Securities Act of 1933 and fix PFIC taxation"
Good news for US investors! Metaplanet (Japanese public company) received a favorable PFIC assessment. Unlikely to be classified as a PFIC in 2025, and likely to remain that way if current operations continue. This means simpler tax implications for US shareholders. #Metaplanet #PFIC #Bitcoin
July 29, 2025 at 12:52 AM
Good news for US investors! Metaplanet (Japanese public company) received a favorable PFIC assessment. Unlikely to be classified as a PFIC in 2025, and likely to remain that way if current operations continue. This means simpler tax implications for US shareholders. #Metaplanet #PFIC #Bitcoin
Progressive Familial Intrahepatic Cholestasis (PFIC) is a rare genetic liver disease in infants and children that causes severe itching, jaundice, and liver failure.
Learn more: pfic.org
You may be rare, but you're not alone!
#rareDisease #rareDiseaseAwareness
Learn more: pfic.org
You may be rare, but you're not alone!
#rareDisease #rareDiseaseAwareness
July 14, 2026 at 2:00 PM
Progressive Familial Intrahepatic Cholestasis (PFIC) is a rare genetic liver disease in infants and children that causes severe itching, jaundice, and liver failure.
Learn more: pfic.org
You may be rare, but you're not alone!
#rareDisease #rareDiseaseAwareness
Learn more: pfic.org
You may be rare, but you're not alone!
#rareDisease #rareDiseaseAwareness
非PFICな運用先のアイディア募集中です。
May 24, 2025 at 4:22 PM
非PFICな運用先のアイディア募集中です。
みんなに教えたいこと
日米二重国籍者は気軽な気持ちでイデコや積み立てニーサに手を出してはいけない。
どちらもPFICに引っかかって、税務処理がクッソ面倒なことになる。
私は一口座あたり毎年3万円払って税務処理をしてもらっている。とんでもねー額である。そしてイデコは途中で解約できないので、毎年3万円がかかり続けるということ。3万円以上リターンがないとペイできない。
日米二重国籍者は気軽な気持ちでイデコや積み立てニーサに手を出してはいけない。
どちらもPFICに引っかかって、税務処理がクッソ面倒なことになる。
私は一口座あたり毎年3万円払って税務処理をしてもらっている。とんでもねー額である。そしてイデコは途中で解約できないので、毎年3万円がかかり続けるということ。3万円以上リターンがないとペイできない。
June 6, 2025 at 3:30 AM
みんなに教えたいこと
日米二重国籍者は気軽な気持ちでイデコや積み立てニーサに手を出してはいけない。
どちらもPFICに引っかかって、税務処理がクッソ面倒なことになる。
私は一口座あたり毎年3万円払って税務処理をしてもらっている。とんでもねー額である。そしてイデコは途中で解約できないので、毎年3万円がかかり続けるということ。3万円以上リターンがないとペイできない。
日米二重国籍者は気軽な気持ちでイデコや積み立てニーサに手を出してはいけない。
どちらもPFICに引っかかって、税務処理がクッソ面倒なことになる。
私は一口座あたり毎年3万円払って税務処理をしてもらっている。とんでもねー額である。そしてイデコは途中で解約できないので、毎年3万円がかかり続けるということ。3万円以上リターンがないとペイできない。
iDeCo（や他の日本の税優遇リタイアメント口座）のPFICの扱い、昔にどこかのUS citizens in Japan的なforumを覗いたときは、PFIC対象だから少なくともiDeCoはやめましょう説で大体統一されていた気がする。NISAは忘れた。多分彼らがよく使っている税理士、知らんけどDeloitteとか？がそう指導しているだけかなとは思うけど。
真相はIRS、またはIRSからauditされた人だけが知る…とかそういう感じなんだろうか？
真相はIRS、またはIRSからauditされた人だけが知る…とかそういう感じなんだろうか？
February 22, 2024 at 6:32 PM
iDeCo（や他の日本の税優遇リタイアメント口座）のPFICの扱い、昔にどこかのUS citizens in Japan的なforumを覗いたときは、PFIC対象だから少なくともiDeCoはやめましょう説で大体統一されていた気がする。NISAは忘れた。多分彼らがよく使っている税理士、知らんけどDeloitteとか？がそう指導しているだけかなとは思うけど。
真相はIRS、またはIRSからauditされた人だけが知る…とかそういう感じなんだろうか？
真相はIRS、またはIRSからauditされた人だけが知る…とかそういう感じなんだろうか？