Scientists develop double-punch immunotherapy to kill prostate cancer
interestingengineering.com/health/immun...
interestingengineering.com/health/immun...
Scientists develop double-punch immunotherapy to kill prostate cancer
Researchers have discovered a new approach to prostate cancer treatment by combining immunotherapy with PIM1 kinase inhibition.
interestingengineering.com
March 6, 2025 at 3:25 AM
Scientists develop double-punch immunotherapy to kill prostate cancer
interestingengineering.com/health/immun...
interestingengineering.com/health/immun...
Our new paper is out 🎉 in @narjournal.bsky.social
A fascinating complex composed of Mrx6, Mam33, and Pim1 controls #mtDNA copy number by regulating Lon-dependent substrate turnover in #yeast.
Congrats to @simonrecyclable.bsky.social, all co-authors and collaborators!
academic.oup.com/nar/article/...
A fascinating complex composed of Mrx6, Mam33, and Pim1 controls #mtDNA copy number by regulating Lon-dependent substrate turnover in #yeast.
Congrats to @simonrecyclable.bsky.social, all co-authors and collaborators!
academic.oup.com/nar/article/...
Mrx6 binds the Lon protease Pim1 N-terminal domain to confer selective substrate specificity and regulate mtDNA copy number
Abstract. Mitochondrial DNA (mtDNA) copy number regulation remains incompletely understood, despite its importance in cellular function. In Saccharomyces c
academic.oup.com
January 15, 2026 at 3:40 PM
Our new paper is out 🎉 in @narjournal.bsky.social
A fascinating complex composed of Mrx6, Mam33, and Pim1 controls #mtDNA copy number by regulating Lon-dependent substrate turnover in #yeast.
Congrats to @simonrecyclable.bsky.social, all co-authors and collaborators!
academic.oup.com/nar/article/...
A fascinating complex composed of Mrx6, Mam33, and Pim1 controls #mtDNA copy number by regulating Lon-dependent substrate turnover in #yeast.
Congrats to @simonrecyclable.bsky.social, all co-authors and collaborators!
academic.oup.com/nar/article/...
🚀 Excited to share our latest work on Mrx6 and mtDNA copy number regulation, now available on @biorxivpreprint.bsky.social ! We uncover how Mrx6 and Mam33 interact with the Lon protease Pim1 to control substrate degradation. 🔬 Check it out here: www.biorxiv.org/content/10.1... #mitochondria #mtDNA
Mrx6 binds the Lon protease Pim1 N-terminal domain to confer selective substrate specificity and regulate mtDNA copy number
Mitochondrial DNA (mtDNA) copy number regulation remains incompletely understood, despite its importance in cellular function. In Saccharomyces cerevisiae, Mrx6 belongs to the Pet20-domain-containing ...
www.biorxiv.org
February 16, 2025 at 2:04 PM
🚀 Excited to share our latest work on Mrx6 and mtDNA copy number regulation, now available on @biorxivpreprint.bsky.social ! We uncover how Mrx6 and Mam33 interact with the Lon protease Pim1 to control substrate degradation. 🔬 Check it out here: www.biorxiv.org/content/10.1... #mitochondria #mtDNA
PIM1 kinase–regulated cellular metabolism sustains differentiation and function of effector CD8+ T cells during chronic viral infection @jimmunol.bsky.social @feinberg.northwestern.edu
academic.oup.com/jimmunol/art...
academic.oup.com/jimmunol/art...
April 21, 2026 at 2:22 PM
PIM1 kinase–regulated cellular metabolism sustains differentiation and function of effector CD8+ T cells during chronic viral infection @jimmunol.bsky.social @feinberg.northwestern.edu
academic.oup.com/jimmunol/art...
academic.oup.com/jimmunol/art...
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🔬Study reveals how #Yeast regulates mitochondrial DNA copy number: Mrx6 forms complex with Mam33 to modulate Lon protease Pim1 substrate specificity, controlling degradation of key mtDNA maintenance proteins Rpo41 and Cim1
www.yeastgenome.org/reference/S1...
#YeastResearch #SGD #MitochondrialBiology
www.yeastgenome.org/reference/S1...
#YeastResearch #SGD #MitochondrialBiology
January 22, 2026 at 12:56 AM
🔬Study reveals how #Yeast regulates mitochondrial DNA copy number: Mrx6 forms complex with Mam33 to modulate Lon protease Pim1 substrate specificity, controlling degradation of key mtDNA maintenance proteins Rpo41 and Cim1
www.yeastgenome.org/reference/S1...
#YeastResearch #SGD #MitochondrialBiology
www.yeastgenome.org/reference/S1...
#YeastResearch #SGD #MitochondrialBiology
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Our vinyl material is a very sensual experience. We use the softest, most rubbery feeling material that is possible to produce. This is our RA96 Jessica Raincoat in our NAT10 vinyl with our TO22 bathing suit shown in PIM1 color. Makeitkinky.com #sensual #sensation #fetish #materialsfetish #bdsm
Excited to share our new preprint on Mrx6, who binds the Lon protease Pim1 N-terminal domain through a bipartite motif to confer selective substrate specificity and regulate mtDNA copy number! Looking forward to all your feedback and follow-ups! A huge thank you to everyone who contributed!
Mrx6 binds the Lon protease Pim1 N-terminal domain to confer selective substrate specificity and regulate mtDNA copy number
Mitochondrial DNA (mtDNA) copy number regulation remains incompletely understood, despite its importance in cellular function. In Saccharomyces cerevisiae, Mrx6 belongs to the Pet20-domain-containing ...
www.biorxiv.org
February 16, 2025 at 1:59 PM
Excited to share our new preprint on Mrx6, who binds the Lon protease Pim1 N-terminal domain through a bipartite motif to confer selective substrate specificity and regulate mtDNA copy number! Looking forward to all your feedback and follow-ups! A huge thank you to everyone who contributed!
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This is our UN19 Bo Peep dress in PIM1 color. Made of solid PVC plastic with no fabric lining. Our material feels extremely soft and rubbery. Makeitkinky.com #plasticraincoat #plasticpants #pvcfetish #plasticlover #latexfetish
This is our UN19 Bo Peep dress in PIM1 color. Made of solid PVC plastic with no fabric lining. Our material feels extremely soft and rubbery. Makeitkinky.com #plasticraincoat #plasticpants #pvcfetish #plasticlover #latexfetish
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