#PITT_ID2025
Interesting article about early versus deferred antiretroviral treatment initiation for HIV and long-term cardiovascular disease. #PITT_ID2025

academic.oup.com/ofid/article...
Early versus deferred antiretroviral therapy initiation and long-term cardiovascular disease outcomes in people with HIV: The START study
While it is known that HIV increases cardiovascular disease (CVD) risk in people with immunodeficiency, we did not find evidence that delaying treatment in
academic.oup.com
September 26, 2025 at 4:21 PM
Pectus ecvavatum is a condition of congenital chest wall deformity. When undergoing invasive pectus excavatum repairs, researchers investigated if post-operative antimicrobial prophylaxis should be considered. #PITT_ID2025

jamanetwork.com/journals/jam...
Postoperative Antimicrobial Prophylaxis Use and Outcomes in Pectus Excavatum Repair
This cohort study assesses the association of postoperative antibiotic prophylaxis with surgical site infections and other postoperative outcomes in children undergoing minimally invasive pectus excav...
jamanetwork.com
September 4, 2025 at 7:04 PM
In a double-blind, placebo-controlled phase 2 clinical trial, azelastine 0.1% nasal spray has been shown to have a 2.2% infection rate in 227 participants for SARS-CoV-2 as compared to placebo group 6.7% of 223 participants.
#PITT_ID2025
jamanetwork.com/journals/jam...
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jamanetwork.com
September 4, 2025 at 6:23 PM
who.int WHO @who.int · Apr 26
Uganda has declared the end of Ebola disease outbreak, less than three months after the virus was confirmed.

Robust, coordinated response by the government, supported by WHO and partners, was critical in stopping the outbreak.
April 27, 2025 at 1:46 AM
Treating for Pseudomonas aeruginosa varies between ICU and non-ICU settings. Eid and colleagues take a look at current treatment guidelines for this pathogen and each antimicrobial agent resistant pattern. #PITT_ID2025

www.nature.com/articles/s41...
Comparison of antimicrobial resistance in Pseudomonas aeruginosa from intensive care and non-intensive care units and its impact on treatment decisions - Scientific Reports
Scientific Reports - Comparison of antimicrobial resistance in Pseudomonas aeruginosa from intensive care and non-intensive care units and its impact on treatment decisions
www.nature.com
April 17, 2025 at 12:32 PM
Antimicrobials for Pseudomonas aeruginosa is often over-prescribed in the hospital setting. This study investigates proper risk assessment diagnostics to mitigate unnecessary antimicrobial resistance. #PITT_ID2025

aricjournal.biomedcentral.com/articles/10....
Risk factors for detection of Pseudomonas aeruginosa in clinical samples upon hospital admission - Antimicrobial Resistance & Infection Control
Background/introduction Antipseudomonal antibiotics are frequently used in patients admitted to hospitals. Many of these substances are classified as a reserve or watch status by the WHO. Inappropriat...
aricjournal.biomedcentral.com
April 9, 2025 at 3:33 PM
Christopher Gregory and his research team investigate incidence rates of group A stretococcus infections in ten U.S. states. From 2013 to 2022, they saw a large trend of cases increase in the past decade. #PITT_ID2025

jamanetwork.com/journals/jam...
Invasive Group A Streptococcal Infections in 10 US States
This population-based surveillance study investigates trends in the incidence, characteristics, antimicrobial resistance, and outcomes of invasive group A Streptococcus infections among individuals in...
jamanetwork.com
April 9, 2025 at 3:25 PM
April 8, 2025 at 6:03 PM
There is an outbreak growing in measles at this moment. The rise in cases can be depicted in the graph shown in this article. #PITT_ID2025

publications.aap.org/redbook/reso...
Red Book Online Outbreaks: Measles
ul { line-height: 1.75; } Measles Cases in 2025As of March 27, 2025, a total of 483 confirmed measles cases were reported by 20 jurisdictions: Alaska, California, Florida, Georgia, Kansas, Kentucky, M...
publications.aap.org
April 1, 2025 at 3:44 AM
Important study looking behind the drug resistance of piperacillin/tazobactam to Bacteroides fragilis from 8.5% in 2012 to 42.7% in 2022. #PITT_ID2025

www.tandfonline.com/doi/full/10....
A seemingly considerable increase in antimicrobial resistance in the Bacteroides fragilis group from blood cultures – the second national study in Denmark
Bacteroides fragilis group species are the most frequently encountered bacteria involved in anaerobic bacteraemia and associated with high mortality rates. In 2012, we performed the first national ...
www.tandfonline.com
April 1, 2025 at 1:57 AM
I am surprised to see vegetables to be a second food source for causing salmonella enterica. #PITT_ID2025

wwwnc.cdc.gov/eid/article/...
Attribution of <em>Salmonella enterica</em> to Food Sources by Using Whole-Genome Sequencing Data
Attribution of <em>Salmonella enterica</em> to Food Sources
wwwnc.cdc.gov
March 26, 2025 at 9:24 PM
Many antibiotics are prescribed for 14 days in uncomplicated gram-negative bloodstream infections. This article takes a look in using 7-day regimens to help improve anti-microbial stewardship. #PITT_ID2025

jamanetwork.com/journals/jam...
Seven vs Fourteen Days of Antibiotics for Gram-Negative Bloodstream Infection
This systematic review and noninferiority meta-analysis applies bayesian statistics to randomized clinical trials comparing 7 vs 14 days of antibiotic therapy among patients with Gram-negative bloodst...
jamanetwork.com
March 26, 2025 at 9:15 PM
Here is another article integrating antimicrobial stewardship in chronic obstructive pulmonary disease through point of care testing to help guide appropriate antimicrobial use. #PITT_ID2025

www.ijidonline.com/article/S120...
Point-of-care testing reduces antibiotic prescribing in acute exacerbations of chronic obstructive pulmonary disease: a systematic review and meta-analysis
Chronic obstructive pulmonary disease (COPD) imposes a significant global health burden as the third leading cause of death worldwide. In 2019, COPD was responsible for 3.23 million deaths globally [1...
www.ijidonline.com
March 19, 2025 at 5:48 PM
This article takes a look into antimicrobial stewardship by critiquing suppressive antibiotic therapy use for prosthetic joint infection. The focus is to reduce antimicrobial use to avoid unnecessary resistance rates. #PITT_ID2025

jamanetwork.com/journals/jam...
Decisions About Suppressive Antibiotics After Prosthetic Joint Infection
This qualitative study characterizes clinical decision-making about suppressive antibiotic therapy after prosthetic joint infection and identifies stewardship intervention opportunities to stop or red...
jamanetwork.com
March 19, 2025 at 5:40 PM
This article introduces a vaccine for preventing Chlamydia trachomatis which is a highly prevalent bacteria causing sexually transmitted infection around the world. #PITT_ID2025

www.ijidonline.com/article/S120...
Innovative Approach for the Clinical Development of a Chlamydia trachomatis Vaccine Through a Human-Challenge Model in Women
Chlamydia trachomatis is the most prevalent bacterial sexually transmitted infection globally. Although antibiotic treatment is highly effective, most infections go undetected and untreated because th...
www.ijidonline.com
March 11, 2025 at 3:46 AM
This article takes a look into prophylactic use of antibiotics in children with cholecystectomy where the Infectious Disease Society of America recommends against in adult surgical populations, but not specified for children. #PITT_ID2025

jamanetwork.com/journals/jam...
Antimicrobial Prophylaxis Use and Outcomes for Children Undergoing Cholecystectomy
This cohort study compares surgical site infection outcomes between children undergoing cholecystectomy who received prophylaxis and those who did not.
jamanetwork.com
March 11, 2025 at 3:41 AM
Interesting article about how climate change is affecting the prevelance of coccidioidomycosis. Infections with this bacteria hit high in California in 2023. #PITT_ID2025

jamanetwork.com/journals/jam...
Climate Change and Coccidioidomycosis
This JAMA Insights discusses the increased risk of coccidioidomycosis due to climate change and the importance of clinicians, patients, and health systems being educated about the disease to ensure ac...
jamanetwork.com
February 26, 2025 at 3:15 AM
This study focuses on the use of IV and PO antibiotics in the treatment of fractured related infections. #PITT_ID2025

jamanetwork.com/journals/jam...
Oral vs Intravenous Antibiotics for Fracture-Related Infections
The POvIV randomized clinical trial evaluates the effectiveness of treatment of fracture-related infection with oral vs intravenous antibiotics across 24 trauma centers in the US among patients aged 1...
jamanetwork.com
February 18, 2025 at 5:49 PM