#PLOSPathogens
In reality:

1. Roughly half of historical Ebola outbreaks are linked to wildlife use, while the other half are something of a mystery.
September 25, 2026 at 7:36 PM
#PhageSky is curious to learn more about this fancy phage 👋
March 2, 2026 at 2:53 PM
Autoimmunität ausgelöst? Ist es eine frühere oder eine aktuelle Infektion, die zu den vielen Befunden von Immunstörungen bei #MECFS geführt hat?“

https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1011523

#LongCovid COVID19 #Coronavirus #SARSCoV2 #Enterovirus #MaskUp #CleanAir
August 20, 2023 at 10:44 PM
The best way to start 2025: our latest work is out in #PLOSPathogens. It discusses ApiAP2 transcription factors and daughter cell assembly in T. gondii. A work spearheaded by @be-maanasa.bsky.social with the contribution of @mudiyamv.bsky.social
dx.plos.org/10.1371/jour...
Cascading expression of ApiAP2 transcription factors controls daughter cell assembly in Toxoplasma gondii
Author summary Toxoplasma gondii is a is a unicellular eukaryotic pathogen that infects a wide range of animals. Pathogenesis of this parasite relies on its ability to rapidly proliferate and dissemin...
dx.plos.org
January 2, 2025 at 11:02 AM
Incredibly proud to share that our work on Cryptosporidium Oocyst Wall Proteins is published in
@PLOSPathogens
journals.plos.org/plospathogen...

Led by previous PhD student
@BacchettiRoss
and carried on by current PhD student, Sarah Stevens.
Cryptosporidium oocyst wall proteins are true components of the oocyst wall and COWP8 is not required for parasite transmission
Author summary Infection with Cryptosporidium causes diarrhoea, which can be fatal for malnourished children or people who are immunocompromised. There is no vaccine or effective medicines available t...
journals.plos.org
October 23, 2025 at 6:40 PM
📣 Excited to share our latest PLOS Pathogens paper

We developed a reverse genetics system for Bhanja virus and show that lineage-specific NSs proteins differentially antagonise interferon, affecting viral fitness. 🎉
🔗 doi.org/10.1371/jour...

#Virology #PLOSPathogens
Functional divergence of the Bhanja virus NSs protein modulates interferon antagonism and viral fitness across divergent lineages
Author summary Bhanja virus is a tick-borne virus distributed across Asia, Africa, and Europe that causes neurological disease, yet little is known about how it replicates or evades immunity. We devel...
doi.org
September 25, 2026 at 8:15 AM
NEW publication in PLOSPathogens.

Know the enemy and know yourself: Addressing cryptic fungal pathogens of humans and beyond

We outline five key steps toward combatting and preventing disease caused by cryptic fungal pathogens and beyond.

journals.plos.org/plospathogen...
October 20, 2023 at 3:26 PM

A conserved switch controls virulence, sporulation, and motility in C. difficile

#PLOSPathogens

journals.plos.org/plospathogen...
May 14, 2024 at 11:44 AM
Pseudomonas aeruginosa senses and responds to epithelial potassium flux via Kdp operon to promote biofilm

#PLOSPathogens from Jennifer M. Bomberger
with Dominique Limoli @catarmbruster.bsky.social

journals.plos.org/plospathogen...
June 2, 2024 at 1:58 PM
🚀Happy to share that from January 2025, I'll serve as an Academic Editor at PLOSPathogens.

Very pleased to join @plos.bsky.social, it's Publication Model and Handle First-Class Manuscripts from my Peers.

Looking forward to seeing your submission(s) in 2025! 📝🗞️🧫🧬🦠🔬💊
December 6, 2024 at 11:02 AM
Happy to share our publication in #PlosPathogens investigating repression of varicella zoster virus in neuron-like cells: journals.plos.org/plospathogen...
Thanks to @dandepledge.bsky.social and other colleagues for their contribution!
Repression of varicella zoster virus gene expression during quiescent infection in the absence of detectable histone deposition
Author summary Varicella zoster virus (VZV) establishes latent infection exclusively in human neurons. This phase of infection is characterized by restricted viral gene expression, lack of detectable ...
journals.plos.org
February 20, 2025 at 5:26 PM
It's HERE! Our long awaited paper revealing phylogenomic variations in #Salmonella Agona that lead to persistent infection in @PLOSPathogens

dx.plos.org/10.1371/jour...

Thanks Gemma Langridge, UKHSA's, Marie Chattaway
& Amina Ismail Ahmed & Winnie Lee

Now to the next 3 papers..
From acute to persistent infection: revealing phylogenomic variations in Salmonella Agona
Author summary The persistence of non-typhoidal Salmonella following acute gastroenteritis is a significant challenge for public health but the causes that lead to such chronic infections are understu...
dx.plos.org
November 19, 2024 at 9:47 AM
yeah, phages 🤗 «mystique» 🤩 bravo, ellinor 👏
#PhageSky
April 10, 2025 at 9:35 PM
Our study of coronavirus structural proteins that interfere with host responses to infection, led by Drs. Taylor Caddell and Eric Pringle, with support from colleagues @rorymulloy.bksy.social and @corcoranlab.bsky.social, is now published in @PLOSPathogens
journals.plos.org/plospathogen...
(1/8)
Coronavirus M protein disperses the trans-Golgi network and inhibits anterograde protein trafficking in the secretory pathway
Author summary Coronaviruses (CoVs) use the endoplasmic reticulum (ER) for synthesis and processing of viral transmembrane proteins, including those that sculpt ER membranes into replication compartme...
journals.plos.org
May 13, 2026 at 8:58 PM
Brilliant new review in Plos Pathogens looking at how RND efflux pumps contribute to virulence from @ilyasalav.bsky.social and Corella Detweiler. This one is going to be super useful for efflux folks! 🤩https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1014228
How resistance-nodulation-division (RND) efflux pumps contribute to virulence
In Gram-negative bacteria, multi-subunit efflux pumps transport molecules across the inner membrane, periplasm, and outer membrane to the extracellular environment. These efflux pumps include the Resi...
journals.plos.org
May 20, 2026 at 11:20 AM
Dive into our latest study in @PLOS Pathogens where we reveal hidden strategies for the subversion of host translation by the potyvirus TuMV in Arabidopsis

https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1011417

A Blue 🧵
November 21, 2023 at 6:44 PM
Our new manuscript on LTB4 and plague is out in #PLOSPathogens! We used Y. pestis to identify distinct mechanisms of pathogen recognition in leukocytes. Thanks to all our collaborators for much needed help! journals.plos.org/plospathogen...
Distinct mechanisms of type 3 secretion system recognition control LTB4 synthesis in neutrophils and macrophages
Author summary The production of inflammatory lipid mediators by the host is essential for timely inflammation in response to invasion by bacterial pathogens. Therefore, defining how immune cells reco...
journals.plos.org
October 21, 2024 at 12:57 AM
New publication from Pete Gwynne from @TuftsLyme in PlosPathogens doing a deep dive into lipid scavenging by B. burgdorferi. Once again and example of Bb being lazy and depending on its environment 😀 journals.plos.org/plospathogen...
Lipid scavenging by the Lyme disease spirochete Borrelia burgdorferi
Author summary Lyme disease is caused by a bacterium, Borrelia burgdorferi, which has an unusually small genome; it scavenges most of the nutrients it needs to survive from its hosts. This scavenging ...
journals.plos.org
January 15, 2026 at 3:58 AM
Direct and indirect pathways linking the Lon protease to motility behaviors in the pathogen Pseudomonas aeruginosa

#PLOSPathogens from @krijonas.bsky.social

journals.plos.org/plospathogen...
Direct and indirect pathways linking the Lon protease to motility behaviors in the pathogen Pseudomonas aeruginosa
Author summary Proteases specifically degrade other proteins inside cells and constitute promising drug targets due to their central roles in cell physiology. In the human pathogen Pseudomonas aerugin...
journals.plos.org
June 26, 2025 at 10:21 AM
It's HERE! Our long awaited paper revealing phylogenomic variations in #Salmonella Agona that lead toward persistent infection in @PLOSPathogens

https://t.co/iDY38oiVbJ

Great job to our @EmmaBeansworth, @gemma_langridge,@Winni_l08 & @UKHSA's @MarieChattaway & Amina Ismail Ahmed
November 20, 2024 at 1:57 PM
#PLOSPathogens: Casein Kinases 2-dependent phosphorylation of the placental ligand VAR2CSA regulates Plasmodium falciparum-infected erythrocytes cytoadhesion. (ParaFrap Team: Benoit Gamain) dx.plos.org/10.1371/jour... @plos.org
Casein Kinases 2-dependent phosphorylation of the placental ligand VAR2CSA regulates Plasmodium falciparum-infected erythrocytes cytoadhesion
Author summary Plasmodium falciparum-infected erythrocytes (IEs) isolated from pregnant women suffering from malaria express at their surface a specific variant of the P. falciparum Erythrocyte Membra...
dx.plos.org
February 10, 2025 at 10:03 AM
Excited to see our study published in @PLOSPathogens. Multi-stage activity & single oral dose killing of P. falciparum in vivo. Structural basis for improved potency and selectivity of this reaction-hijacking inhibitor are revealed. doi.org/10.1371/journal.ppat.1012429
December 19, 2024 at 9:17 PM
Crosstalk between circadian clocks and pathogen niche

#PLOSPathogens Review

journals.plos.org/plospathogen...
May 14, 2024 at 12:41 PM
Study from my Lab detailing how Aerobactin-mediated iron acquisition is critical for hypervirulent Klebsiella to disseminate from the gut to cause invasive disease. Tour de Force work led by my wonderful Grad student, Giovanna Hernandez! #PLoSPathogens #Klebsiella journals.plos.org/plospathogen...
Aerobactin is a key driver of hypervirulent Klebsiella pneumoniae translocation and virulence
Author summary The emergence of hypervirulent Klebsiella pneumoniae (hvKP) poses a significant public health threat due to its capacity to cause severe, often fatal, systemic infections. Of further co...
journals.plos.org
April 19, 2026 at 7:30 PM