prnpラフィソルとカレーアルル★7できたー！🙌やーーーっとだよ😭
September 25, 2026 at 7:57 AM
prnpラフィソルとカレーアルル★7できたー！🙌やーーーっとだよ😭
#fluorescenceFriday. Lightsheet 3D movie of S129 Synuclein (magenta) and nuclear marker (green) in M83 mice injected with Synuclein preformed fibrils (also known as PFFs) in the right striatum. Spinal cord lights up because of high expression of human alpha-synuclein driven by the Prnp promoter
March 15, 2025 at 12:32 AM
#fluorescenceFriday. Lightsheet 3D movie of S129 Synuclein (magenta) and nuclear marker (green) in M83 mice injected with Synuclein preformed fibrils (also known as PFFs) in the right striatum. Spinal cord lights up because of high expression of human alpha-synuclein driven by the Prnp promoter
This Fascist Move by Trump’s DOJ Should Terrify You
YouTube video by Rebel HQ
youtube.com
April 13, 2025 at 6:50 PM
last but not least one on in vivo base editing in mice models of prion (PRNP) disease achieved 50% reduction in PrP protein and 52% increase in lifespan.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
December 21, 2025 at 10:09 PM
last but not least one on in vivo base editing in mice models of prion (PRNP) disease achieved 50% reduction in PrP protein and 52% increase in lifespan.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
O que, fazer um CRISPR pra deletar PRNP, botar num vetor e injetar no fluído cérebro-espinhal? Ué, até dá (com a ajuda de um laboratório inteiro de gente)
August 26, 2026 at 2:24 AM
O que, fazer um CRISPR pra deletar PRNP, botar num vetor e injetar no fluído cérebro-espinhal? Ué, até dá (com a ajuda de um laboratório inteiro de gente)
一部のprnp初代キャラの個体がプワープ産なの何故？のツイートを見かけて、(いやいや、そんなまさか…？)と思いながら各キャラのカード説明文を探ったら本当だった……。
えっ？貴方ら15thの世界線設定のキャラじゃないの？
えっ？貴方ら15thの世界線設定のキャラじゃないの？
September 25, 2026 at 12:28 AM
一部のprnp初代キャラの個体がプワープ産なの何故？のツイートを見かけて、(いやいや、そんなまさか…？)と思いながら各キャラのカード説明文を探ったら本当だった……。
えっ？貴方ら15thの世界線設定のキャラじゃないの？
えっ？貴方ら15thの世界線設定のキャラじゃないの？
youtube.com/watch?v=prNP...
THIS is a wake-up call for anyone still in a coma. IS THIS THE COUNTRY YOU WANT TO LIVE IN?
RISE UP NOW!
CALL YOUR REPS AND SENATORS AND DEMAND THEY FIGHT FOR THE CONSTITUTION AND RULE OF LAW!
RAISE YOUR VOICES LOUD!
TO THE STREETS!
SILENCE = ACQUIESCENCE
THIS is a wake-up call for anyone still in a coma. IS THIS THE COUNTRY YOU WANT TO LIVE IN?
RISE UP NOW!
CALL YOUR REPS AND SENATORS AND DEMAND THEY FIGHT FOR THE CONSTITUTION AND RULE OF LAW!
RAISE YOUR VOICES LOUD!
TO THE STREETS!
SILENCE = ACQUIESCENCE
This Fascist Move by Trump’s DOJ Should Terrify You
YouTube video by Rebel HQ
youtube.com
April 13, 2025 at 7:17 PM
youtube.com/watch?v=prNP...
THIS is a wake-up call for anyone still in a coma. IS THIS THE COUNTRY YOU WANT TO LIVE IN?
RISE UP NOW!
CALL YOUR REPS AND SENATORS AND DEMAND THEY FIGHT FOR THE CONSTITUTION AND RULE OF LAW!
RAISE YOUR VOICES LOUD!
TO THE STREETS!
SILENCE = ACQUIESCENCE
THIS is a wake-up call for anyone still in a coma. IS THIS THE COUNTRY YOU WANT TO LIVE IN?
RISE UP NOW!
CALL YOUR REPS AND SENATORS AND DEMAND THEY FIGHT FOR THE CONSTITUTION AND RULE OF LAW!
RAISE YOUR VOICES LOUD!
TO THE STREETS!
SILENCE = ACQUIESCENCE
When you think Trump has hit rock bottom with his attempts to destroy our country you get this kind of shocking revelation, I wanted to cry listening to Liz Oyer! #JesusChrist
www.youtube.com/watch?v=prNP...
www.youtube.com/watch?v=prNP...
This Fascist Move by Trump’s DOJ Should Terrify You
YouTube video by Rebel HQ
www.youtube.com
April 13, 2025 at 7:35 PM
When you think Trump has hit rock bottom with his attempts to destroy our country you get this kind of shocking revelation, I wanted to cry listening to Liz Oyer! #JesusChrist
www.youtube.com/watch?v=prNP...
www.youtube.com/watch?v=prNP...
Learned more about @millermb.bsky.social inspiration and more recent work on #prion proteins
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Neuropathologically directed profiling of PRNP somatic and germline variants in sporadic human prion disease - Acta Neuropathologica
Creutzfeldt–Jakob Disease (CJD), the most common human prion disease, is associated with pathologic misfolding of the prion protein (PrP), encoded by the PRNP gene. Of human prion disease cases, < 1% ...
link.springer.com
December 6, 2024 at 5:54 PM
Learned more about @millermb.bsky.social inspiration and more recent work on #prion proteins
link.springer.com/article/10.1...
link.springer.com/article/10.1...
🦌 Chronic wasting disease (CWD) threatens cervids worldwide. A recent study in Oregon elk reveals a high frequency of the PRNP variant 132L, which may confer some resistance.
(Photo: https://oregonwild.org/)
(Photo: https://oregonwild.org/)
November 30, 2025 at 7:15 PM
🦌 Chronic wasting disease (CWD) threatens cervids worldwide. A recent study in Oregon elk reveals a high frequency of the PRNP variant 132L, which may confer some resistance.
(Photo: https://oregonwild.org/)
(Photo: https://oregonwild.org/)
well there's fatal familial insomnia/the PRNP gene
December 11, 2024 at 5:32 PM
well there's fatal familial insomnia/the PRNP gene
youtube.com/watch?v=prNP...
STOP. FIGHT BACK NOW. ENOUGH OF THIS MISCARRIAGE OF JUSTICE.
STOP. FIGHT BACK NOW. ENOUGH OF THIS MISCARRIAGE OF JUSTICE.
This Fascist Move by Trump’s DOJ Should Terrify You
YouTube video by Rebel HQ
youtube.com
April 14, 2025 at 3:43 AM
youtube.com/watch?v=prNP...
STOP. FIGHT BACK NOW. ENOUGH OF THIS MISCARRIAGE OF JUSTICE.
STOP. FIGHT BACK NOW. ENOUGH OF THIS MISCARRIAGE OF JUSTICE.
Verstehe ich das richtig, daß PRNP in einer Variante vorliegt, die vor Erkrankung durch Prionen schützt?
Und daß wir eine funktionierende Variante brauchen, weshalb darauf hingewiesen wird, daß es heterozygot vorliegt, oder verstehe ich das falsch?
Und daß wir eine funktionierende Variante brauchen, weshalb darauf hingewiesen wird, daß es heterozygot vorliegt, oder verstehe ich das falsch?
December 17, 2025 at 9:43 PM
Verstehe ich das richtig, daß PRNP in einer Variante vorliegt, die vor Erkrankung durch Prionen schützt?
Und daß wir eine funktionierende Variante brauchen, weshalb darauf hingewiesen wird, daß es heterozygot vorliegt, oder verstehe ich das falsch?
Und daß wir eine funktionierende Variante brauchen, weshalb darauf hingewiesen wird, daß es heterozygot vorliegt, oder verstehe ich das falsch?
Did a mutant PRNP prion write this?
September 26, 2023 at 6:37 PM
Did a mutant PRNP prion write this?
No fog! What a gem! Camped at Olema nearby and enjoyed myself at PRNP.
September 27, 2025 at 6:25 PM
No fog! What a gem! Camped at Olema nearby and enjoyed myself at PRNP.
huge thanks to Ralph's grocery in Tustin for apparently being the new 80s/90s-KROQ and inspiring this Song Of The Day(ish). they apparently know their audience.
SOTD 365's fully grown, and knows where it's at...
www.youtube.com/watch?v=PRNP...
#SOTD
#BAD
#BigAudioDynamite
#Rush
SOTD 365's fully grown, and knows where it's at...
www.youtube.com/watch?v=PRNP...
#SOTD
#BAD
#BigAudioDynamite
#Rush
Rush
YouTube video by Big Audio Dynamite - Topic
www.youtube.com
October 24, 2025 at 5:58 AM
huge thanks to Ralph's grocery in Tustin for apparently being the new 80s/90s-KROQ and inspiring this Song Of The Day(ish). they apparently know their audience.
SOTD 365's fully grown, and knows where it's at...
www.youtube.com/watch?v=PRNP...
#SOTD
#BAD
#BigAudioDynamite
#Rush
SOTD 365's fully grown, and knows where it's at...
www.youtube.com/watch?v=PRNP...
#SOTD
#BAD
#BigAudioDynamite
#Rush
#CellularPrion (PRNP) is a membrane glycoprotein, which has been implicated in mouse #decidualization. In this article, the authors demonstrated that PRNP expression is present in #early embryo development and regulates decidual cell function at the maternal-fetal interface.
June 17, 2025 at 1:21 AM
#CellularPrion (PRNP) is a membrane glycoprotein, which has been implicated in mouse #decidualization. In this article, the authors demonstrated that PRNP expression is present in #early embryo development and regulates decidual cell function at the maternal-fetal interface.
I'm scared of prions I haven't eaten beef since I was a small child but that was in the nineties what if they're lurking
There is no cure, after onset of symptoms you lose your mind and then die about a year later
There is no cure, after onset of symptoms you lose your mind and then die about a year later
![Future risk
The original outbreak of vCJD only affected people with a particular genetic makeup; those
who were methionine-homozygous at the PRNP
codon 129 methionine/valine polymorphism
Studies of similar diseases in other parts of the
world have shown that methionine-homozygous
people tend to become ill relatively quickly in a
first wave, while methionine-valine heterozygous
and valine-homozgous people can be infected
but remain asymptomatic for years or even
decades.[35] This has led some researchers
including Graham Jackson of University College
London to warn that there could be a second
wave of CJD infections years later. (35|36]
In 2016, the first case of vCJD with
heterozygosity at codon 129 was identified.[37]
Wikipedia screenshot. Also some Thai text which is the album playing in the pop up window above the text (คณะ รุ่งทวี - แห่สดดนตรีพื้นบ้านหนองโก ชุดหี่ 8+9, listen to it, it bangs)](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:hz2nddanc3palswbxogq76vo/bafkreie5ji4zo66bz5sks5d5d5kwf65f7r6xvijleqwr2wiloyrp3h6jju)
January 16, 2025 at 1:32 AM
I'm scared of prions I haven't eaten beef since I was a small child but that was in the nineties what if they're lurking
There is no cure, after onset of symptoms you lose your mind and then die about a year later
There is no cure, after onset of symptoms you lose your mind and then die about a year later
2/
First let's define prions:
The normal 'prion' protein, PrPc, is a membrane-bound alpha-helical glycolipid that seems to have a role in copper transport in neurons and other cell types.
It's encoded by the PRNP gene.
pubmed.ncbi.nlm.nih.gov/34433091/
First let's define prions:
The normal 'prion' protein, PrPc, is a membrane-bound alpha-helical glycolipid that seems to have a role in copper transport in neurons and other cell types.
It's encoded by the PRNP gene.
pubmed.ncbi.nlm.nih.gov/34433091/
November 14, 2024 at 5:58 PM
2/
First let's define prions:
The normal 'prion' protein, PrPc, is a membrane-bound alpha-helical glycolipid that seems to have a role in copper transport in neurons and other cell types.
It's encoded by the PRNP gene.
pubmed.ncbi.nlm.nih.gov/34433091/
First let's define prions:
The normal 'prion' protein, PrPc, is a membrane-bound alpha-helical glycolipid that seems to have a role in copper transport in neurons and other cell types.
It's encoded by the PRNP gene.
pubmed.ncbi.nlm.nih.gov/34433091/
Neuropathologically-directed profiling of PRNP somatic and germline variants in sporadic human prion disease https://www.biorxiv.org/content/10.1101/2024.06.25.600668v1
Neuropathologically-directed profiling of PRNP somatic and germline variants in sporadic human prion disease https://www.biorxiv.org/content/10.1101/2024.06.25.600668v1
Creutzfeldt-Jakob Disease (CJD), the most common human prion disease, is associated with pathologic
www.biorxiv.org
June 29, 2024 at 10:32 PM
Neuropathologically-directed profiling of PRNP somatic and germline variants in sporadic human prion disease https://www.biorxiv.org/content/10.1101/2024.06.25.600668v1
## 코로나19 mRNA 백신 전달 효율 증진을 위한 리포좀 표면 공액된 펩타이드-RNA 나노입자 (PRNP) 플랫폼 개발
**목차** 1. **서론** * 연구 배경 및 필요성 * 연구 목표 2. **이론적 배경** * mRNA 백신 기술의 현재와 한계 * 리포좀 전달 시스템의 원리 * 펩타이드-RNA 나노입자 (PRNP)의 설계 및 특성 * 공액 기술의 최신 동향 및 활용 3. **연구 방법** * 펩타이드 서열 설계 및 최적화: 펩타이드-RNA 상호작용 및 세포 친화도 극대화 * RNA 나노입자 (RNP) 제작 및 특성…
**목차** 1. **서론** * 연구 배경 및 필요성 * 연구 목표 2. **이론적 배경** * mRNA 백신 기술의 현재와 한계 * 리포좀 전달 시스템의 원리 * 펩타이드-RNA 나노입자 (PRNP)의 설계 및 특성 * 공액 기술의 최신 동향 및 활용 3. **연구 방법** * 펩타이드 서열 설계 및 최적화: 펩타이드-RNA 상호작용 및 세포 친화도 극대화 * RNA 나노입자 (RNP) 제작 및 특성…
## 코로나19 mRNA 백신 전달 효율 증진을 위한 리포좀 표면 공액된 펩타이드-RNA 나노입자 (PRNP) 플랫폼 개발
**목차** 1. **서론** * 연구 배경 및 필요성 * 연구 목표 2. **이론적 배경** * mRNA 백신 기술의 현재와 한계 * 리포좀 전달 시스템의 원리 * 펩타이드-RNA 나노입자 (PRNP)의 설계 및 특성 * 공액 기술의 최신 동향 및 활용 3. **연구 방법** * 펩타이드 서열 설계 및 최적화: 펩타이드-RNA 상호작용 및 세포 친화도 극대화 * RNA 나노입자 (RNP) 제작 및 특성 분석: 크기, 모양, RNA 함량, 안정성 평가
freederia.com
November 30, 2025 at 5:58 AM
## 코로나19 mRNA 백신 전달 효율 증진을 위한 리포좀 표면 공액된 펩타이드-RNA 나노입자 (PRNP) 플랫폼 개발
**목차** 1. **서론** * 연구 배경 및 필요성 * 연구 목표 2. **이론적 배경** * mRNA 백신 기술의 현재와 한계 * 리포좀 전달 시스템의 원리 * 펩타이드-RNA 나노입자 (PRNP)의 설계 및 특성 * 공액 기술의 최신 동향 및 활용 3. **연구 방법** * 펩타이드 서열 설계 및 최적화: 펩타이드-RNA 상호작용 및 세포 친화도 극대화 * RNA 나노입자 (RNP) 제작 및 특성…
**목차** 1. **서론** * 연구 배경 및 필요성 * 연구 목표 2. **이론적 배경** * mRNA 백신 기술의 현재와 한계 * 리포좀 전달 시스템의 원리 * 펩타이드-RNA 나노입자 (PRNP)의 설계 및 특성 * 공액 기술의 최신 동향 및 활용 3. **연구 방법** * 펩타이드 서열 설계 및 최적화: 펩타이드-RNA 상호작용 및 세포 친화도 극대화 * RNA 나노입자 (RNP) 제작 및 특성…
Getting all fired up to some rock vibes as we "ASCEND" into action in Team Sonic Adventures!
www.youtube.com/watch?v=pRnP...
www.youtube.com/watch?v=pRnP...
ASCEND - Team Sonic Adventures (Instrumental)
YouTube video by UltraSonicHero
www.youtube.com
October 14, 2025 at 5:08 PM
Getting all fired up to some rock vibes as we "ASCEND" into action in Team Sonic Adventures!
www.youtube.com/watch?v=pRnP...
www.youtube.com/watch?v=pRnP...