October 28, 2025 at 5:52 PM
Oh, indeed. If you see someone about to do something like this, remind them to mask up!
bsky.app/profile/prrs...
bsky.app/profile/prrs...
Swasticars also have a ton of cameras.
February 1, 2025 at 9:36 PM
Oh, indeed. If you see someone about to do something like this, remind them to mask up!
bsky.app/profile/prrs...
bsky.app/profile/prrs...
Settink ma watsch nao. 4 prrs, gott itt. Gracias, imb awayke!
September 13, 2026 at 7:50 PM
Settink ma watsch nao. 4 prrs, gott itt. Gracias, imb awayke!
Get you a Social Democrat who can also competently serve as a Senior Vice President at a Fortune 500 company
bsky.app/profile/prrs...
bsky.app/profile/prrs...
Leftists refuse to believe that leadership and management skills have any value, let alone more value than operating a kick press.
November 7, 2025 at 7:51 PM
Get you a Social Democrat who can also competently serve as a Senior Vice President at a Fortune 500 company
bsky.app/profile/prrs...
bsky.app/profile/prrs...
Dangerous. This requires soliciting the innate immune system- a generalized network of defenses that focuses on recognizing conserved molecular patterns that occur in danger through pattern recognition receptors (PRRs). For example, we have PRRs that can distinguish between viral and human DNA.
January 24, 2025 at 11:08 PM
Dangerous. This requires soliciting the innate immune system- a generalized network of defenses that focuses on recognizing conserved molecular patterns that occur in danger through pattern recognition receptors (PRRs). For example, we have PRRs that can distinguish between viral and human DNA.
1️⃣ Kent no era socialista. Era del PRRS que no tenía nada que ver con el socialismo de la época.
2️⃣ Campoamor no era radical-socialista, era diputada del PRR de Lerroux. Partido que votó en contra.
3️⃣ Largo Caballero no dijo esa frase.
4️⃣ Caballero defendió el sufragio femenino.
2️⃣ Campoamor no era radical-socialista, era diputada del PRR de Lerroux. Partido que votó en contra.
3️⃣ Largo Caballero no dijo esa frase.
4️⃣ Caballero defendió el sufragio femenino.
July 23, 2026 at 4:49 PM
1️⃣ Kent no era socialista. Era del PRRS que no tenía nada que ver con el socialismo de la época.
2️⃣ Campoamor no era radical-socialista, era diputada del PRR de Lerroux. Partido que votó en contra.
3️⃣ Largo Caballero no dijo esa frase.
4️⃣ Caballero defendió el sufragio femenino.
2️⃣ Campoamor no era radical-socialista, era diputada del PRR de Lerroux. Partido que votó en contra.
3️⃣ Largo Caballero no dijo esa frase.
4️⃣ Caballero defendió el sufragio femenino.
Very happy to share our latest work “Systematic discovery and engineering of synthetic immune receptors in plants” out in @science.org !
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Systematic discovery and engineering of synthetic immune receptors in plants
Plants deploy a diverse array of pattern recognition receptors (PRRs), which perceive microbe-associated molecular patterns to activate immune responses. Leucine-rich repeat receptor-like kinase subgr...
www.science.org
September 4, 2025 at 7:33 PM
Very happy to share our latest work “Systematic discovery and engineering of synthetic immune receptors in plants” out in @science.org !
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
We also have PRRs that recognize the presence of molecules that occur only when there is damage to the cell. The problem is: a purified viral or bacterial protein does not have these conserved molecular features. Yes, some of them are able to bind and trigger PRRs but it is not an inherent property.
January 24, 2025 at 11:08 PM
We also have PRRs that recognize the presence of molecules that occur only when there is damage to the cell. The problem is: a purified viral or bacterial protein does not have these conserved molecular features. Yes, some of them are able to bind and trigger PRRs but it is not an inherent property.
🪲 REVIEW 🪲
This review uncovers the critical role of the plant cell wall in pest defence, integrating structural, molecular, and genetic insights to highlight its emerging significance in plant–pest interactions during herbivory - Perez-Alonso et al.
🔗 doi.org/10.1093/jxb/...
#PlantScience 🧪
This review uncovers the critical role of the plant cell wall in pest defence, integrating structural, molecular, and genetic insights to highlight its emerging significance in plant–pest interactions during herbivory - Perez-Alonso et al.
🔗 doi.org/10.1093/jxb/...
#PlantScience 🧪
November 24, 2025 at 11:57 AM
🪲 REVIEW 🪲
This review uncovers the critical role of the plant cell wall in pest defence, integrating structural, molecular, and genetic insights to highlight its emerging significance in plant–pest interactions during herbivory - Perez-Alonso et al.
🔗 doi.org/10.1093/jxb/...
#PlantScience 🧪
This review uncovers the critical role of the plant cell wall in pest defence, integrating structural, molecular, and genetic insights to highlight its emerging significance in plant–pest interactions during herbivory - Perez-Alonso et al.
🔗 doi.org/10.1093/jxb/...
#PlantScience 🧪
*cuddles and prrs* 💗!!
August 11, 2026 at 4:26 AM
*cuddles and prrs* 💗!!
New preprint by Judith Fliegmann and Lisha Zhang on an additional regulatory layer of #plantimmunity:
the TIR-domain production of small molecules (typical during ETI) is required for PTI responses downstream of RLPs PRRs
#MPMI #ZMBP
the TIR-domain production of small molecules (typical during ETI) is required for PTI responses downstream of RLPs PRRs
#MPMI #ZMBP
Small Molecule Binding to EDS1/PAD4 in LRR-RP-Mediated Pattern-Triggered Immunity https://www.biorxiv.org/content/10.64898/2025.12.10.692544v1
December 13, 2025 at 9:16 AM
New preprint by Judith Fliegmann and Lisha Zhang on an additional regulatory layer of #plantimmunity:
the TIR-domain production of small molecules (typical during ETI) is required for PTI responses downstream of RLPs PRRs
#MPMI #ZMBP
the TIR-domain production of small molecules (typical during ETI) is required for PTI responses downstream of RLPs PRRs
#MPMI #ZMBP
as the amount you squish the cat increases the more she prrs
April 2, 2026 at 9:02 PM
as the amount you squish the cat increases the more she prrs
A great read to start off this semester! Check out this review of PRR evolution and current experimental methods to identify PRRs.
#planthealth #plantbiology 🌾🧪
#planthealth #plantbiology 🌾🧪
Plant pattern recognition receptors: from evolutionary insight to engineering - Nature Reviews Genetics
Genomic and pangenomic data are yielding insights into the evolution of plant pattern recognition receptors (PRRs) and their molecular triggers. Recent advances in in silico and in vivo methods, along...
www.nature.com
January 13, 2025 at 6:21 PM
A great read to start off this semester! Check out this review of PRR evolution and current experimental methods to identify PRRs.
#planthealth #plantbiology 🌾🧪
#planthealth #plantbiology 🌾🧪
First post on Bluesky!! ☀️
Very happy to share that my main postdoc work ‘Systematic Discovery and Design of Synthetic Immune Receptors in Plants’ is finally out on Biorxiv!
www.biorxiv.org/content/10.1...
The full story is summarized here:
Very happy to share that my main postdoc work ‘Systematic Discovery and Design of Synthetic Immune Receptors in Plants’ is finally out on Biorxiv!
www.biorxiv.org/content/10.1...
The full story is summarized here:
Systematic Discovery and Design of Synthetic Immune Receptors in Plants
Plants deploy a diverse array of pattern recognition receptors (PRRs) that perceive microbe-associated molecular patterns (MAMPs) to activate immune responses. Leucine-rich repeat receptor-like kinase...
www.biorxiv.org
March 18, 2025 at 2:01 AM
First post on Bluesky!! ☀️
Very happy to share that my main postdoc work ‘Systematic Discovery and Design of Synthetic Immune Receptors in Plants’ is finally out on Biorxiv!
www.biorxiv.org/content/10.1...
The full story is summarized here:
Very happy to share that my main postdoc work ‘Systematic Discovery and Design of Synthetic Immune Receptors in Plants’ is finally out on Biorxiv!
www.biorxiv.org/content/10.1...
The full story is summarized here:
Jenseits von „Brain Fog“: Virale Proteine als konvergente Treiber von Neuroinflammation und Proteinopathie
„Brain Fog“ könnte nur die sichtbare Spitze des Eisbergs sein: Es wird Zeit für ein Umdenken. Eine neue Sichtweise, welche die Risiken einer Infektion ganzheitlich …
„Brain Fog“ könnte nur die sichtbare Spitze des Eisbergs sein: Es wird Zeit für ein Umdenken. Eine neue Sichtweise, welche die Risiken einer Infektion ganzheitlich …
![Abbildung 1. Übersicht über die hypothetische konvergente Wirkung von Neuroinflammation und Proteinopathie [ 1] . Virale Proteine, wie das hier exemplarisch dargestellte S1-Protein, fungieren als klassische pathogenassoziierte molekulare Muster (PAMPs) und binden an Mustererkennungsrezeptoren (PRRs) auf Gliazellen, um eine chronische, neurotoxische Entzündungskaskade auszulösen. Die Interaktion von mikroglialem S1 mit TLR4 aktiviert kanonische Signalwege, darunter NF-κB und p38 MAPK. Dies führt entscheidend zur Bildung des NLRP3-Inflammasoms und zur Freisetzung von entzündungsfördernden Zytokinen (IL-18, IL-1β). Auch Astrozyten erkennen S1 über eine spezifische TLR2-MyD88-TBK1-Achse und initiieren so eine starke Produktion von Typ-I-Interferon (IFN-I). Dadurch entsteht ein entzündliches Milieu, ein wichtiger Faktor für neuronale Schäden. [2] Neben akuten Entzündungen können virale Proteine wie das S1-Protein chronische Reservoirs in den Hirnhäuten bilden und von dort aus als „Startpunkt“ für chronische, sich selbst verstärkende Proteinopathien wirken. Es ist bekannt, dass das S1-Protein die Aggregation von Wirtsproteinen (z. B. Alpha-Synuclein) katalysiert und das damit verbundene Entzündungsmilieu die Phosphorylierung von Tau beschleunigt; beide Pathologien sind zentral für neurodegenerative Erkrankungen. Abbildung erstellt mit BioRender.com . NLRP3-Inflammasom, NACHT-/LRP-/PYD-haltiges Protein 3; N-GSDMD, Gasdermin D; IL-18, Interleukin-18; IL-1β, Interleukin-1β; p38-MAPK, p38-Mitogen-aktivierte Proteinkinase; NF-κB, Nukleärer Faktor Kappa-B-Verstärker aktivierter B-Zellen. TLR, Toll-like-Rezeptor; TBK-1, Tank-bindende Kinase 1.](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:zxxec4ic2lwsyf3vlaci7ub2/bafkreiaa5lup3l4qgu2pkij553f33ffvdpz67wp5m4kmgqohmiukyiztxu)
June 7, 2026 at 8:30 PM
Jenseits von „Brain Fog“: Virale Proteine als konvergente Treiber von Neuroinflammation und Proteinopathie
„Brain Fog“ könnte nur die sichtbare Spitze des Eisbergs sein: Es wird Zeit für ein Umdenken. Eine neue Sichtweise, welche die Risiken einer Infektion ganzheitlich …
„Brain Fog“ könnte nur die sichtbare Spitze des Eisbergs sein: Es wird Zeit für ein Umdenken. Eine neue Sichtweise, welche die Risiken einer Infektion ganzheitlich …
remembering that i never specified what the prrs got printed on their new dog tags and exhausted by the fact zack probably put “baby” on there somewhere
December 21, 2024 at 4:43 AM
remembering that i never specified what the prrs got printed on their new dog tags and exhausted by the fact zack probably put “baby” on there somewhere
impressionante como essas prrs só jogam contra o Flamengo.
September 15, 2024 at 1:21 AM
impressionante como essas prrs só jogam contra o Flamengo.
¡Sin correos pendientes, prrs!
a little girl in a yellow jacket is eating cotton candy in a crowded stadium .
ALT: a little girl in a yellow jacket is eating cotton candy in a crowded stadium .
media.tenor.com
January 10, 2025 at 3:11 AM
¡Sin correos pendientes, prrs!
In this innate immunity focus issue, Roy Parker and colleagues discuss how condensation of pattern recognition receptors (PRRs) with foreign nucleic acids is regulated in innate immune activation. http://dlvr.it/TNkyJ0
October 17, 2025 at 7:14 PM
In this innate immunity focus issue, Roy Parker and colleagues discuss how condensation of pattern recognition receptors (PRRs) with foreign nucleic acids is regulated in innate immune activation. http://dlvr.it/TNkyJ0
You’re assuming they’re aware of every title withheld from them.
This list is only a small piece of the censorship happening in FL. Internal reviews are also happening and those decisions to permanently remove are rarely made public. We file PRRs trying to capture them, but we don’t get them all.
This list is only a small piece of the censorship happening in FL. Internal reviews are also happening and those decisions to permanently remove are rarely made public. We file PRRs trying to capture them, but we don’t get them all.
January 26, 2025 at 4:07 PM
You’re assuming they’re aware of every title withheld from them.
This list is only a small piece of the censorship happening in FL. Internal reviews are also happening and those decisions to permanently remove are rarely made public. We file PRRs trying to capture them, but we don’t get them all.
This list is only a small piece of the censorship happening in FL. Internal reviews are also happening and those decisions to permanently remove are rarely made public. We file PRRs trying to capture them, but we don’t get them all.
@kseniakrasileva.bsky.social is the first talk at the engineering traits session at #2025ISMPMI
Branching into PRRs thanks to @danimstevens.bsky.social.
The ?: Can we use language models to predict host and microbe proteins interaction outcomes?
The answer: Yes! New “mamp-ml”does pretty well.
Branching into PRRs thanks to @danimstevens.bsky.social.
The ?: Can we use language models to predict host and microbe proteins interaction outcomes?
The answer: Yes! New “mamp-ml”does pretty well.
July 17, 2025 at 8:41 AM
@kseniakrasileva.bsky.social is the first talk at the engineering traits session at #2025ISMPMI
Branching into PRRs thanks to @danimstevens.bsky.social.
The ?: Can we use language models to predict host and microbe proteins interaction outcomes?
The answer: Yes! New “mamp-ml”does pretty well.
Branching into PRRs thanks to @danimstevens.bsky.social.
The ?: Can we use language models to predict host and microbe proteins interaction outcomes?
The answer: Yes! New “mamp-ml”does pretty well.
A lot of the work being done IS public records. Literally. For years, folks like @flfreedomread.bsky.social and @txfreedomread.bsky.social have spent gobs of their own money filing FOIAS/PRRs to get this info.
October 9, 2025 at 3:03 PM
A lot of the work being done IS public records. Literally. For years, folks like @flfreedomread.bsky.social and @txfreedomread.bsky.social have spent gobs of their own money filing FOIAS/PRRs to get this info.
1️⃣ No se opuso "LA IZQUIERDA", fue una parte.
2️⃣ No votó a favor "LA DERECHA", fue una parte.
3️⃣ De los 161 síes la mayoría era de izquierda: 113. Por ejemplo, 84 eran PSOE.
4️⃣ Hay que sumar otros: 4 PRDF; 3 AR; 2 PRRS y 2 USC. Hacen 95 diputados.
2️⃣ No votó a favor "LA DERECHA", fue una parte.
3️⃣ De los 161 síes la mayoría era de izquierda: 113. Por ejemplo, 84 eran PSOE.
4️⃣ Hay que sumar otros: 4 PRDF; 3 AR; 2 PRRS y 2 USC. Hacen 95 diputados.
February 3, 2025 at 2:32 PM
1️⃣ No se opuso "LA IZQUIERDA", fue una parte.
2️⃣ No votó a favor "LA DERECHA", fue una parte.
3️⃣ De los 161 síes la mayoría era de izquierda: 113. Por ejemplo, 84 eran PSOE.
4️⃣ Hay que sumar otros: 4 PRDF; 3 AR; 2 PRRS y 2 USC. Hacen 95 diputados.
2️⃣ No votó a favor "LA DERECHA", fue una parte.
3️⃣ De los 161 síes la mayoría era de izquierda: 113. Por ejemplo, 84 eran PSOE.
4️⃣ Hay que sumar otros: 4 PRDF; 3 AR; 2 PRRS y 2 USC. Hacen 95 diputados.