Some framing projects are designed to display something beautiful. Others are created to make sure someone is remembered. Picture Worth Custom Framing recently completed this deeply personal memorial for a fallen police officer and motorcycle rider. Rather than using a conventional mat and simply placing memorabilia around it, PWCF created a custom, multi-layered presentation built specifically around his story. Look Closely—That Isn't an Ordinary Mat The background surrounding the centerpiece is a PWCF-exclusive personalized vinyl-wrapped mat. Instead of relying on a traditional solid-color mat, we used the surface itself to help tell the story.

Sometimes the right custom frame shouldn't compete with the artwork. It should make you notice the artwork before you even realize why the entire presentation works so well. That was the goal with this original piece recently framed by Picture Worth Custom Framing. Why We Used an Outer Frame AND an Inner Fillet Look closely at the finished piece. Rather than surrounding the artwork with one visually heavy frame, PWCF paired a warm wood-toned outer frame with a darker inner fillet. The contrast helps transition the eye from the frame toward the lighter artwork while picking up some of the deeper tones within the piece.

Abstract. Allergic bronchopulmonary aspergillosis (ABPA) is a significant complication in people with cystic fibrosis (pwCF), driven by hypersensitivity to

Polymicrobial interactions impact disease outcomes in pwCF who suffer from chronic respiratory infections. Previous work established a CF-relevant polymicrobial community model that allows experimenta...

Cystic fibrosis (CF) is an autosomal recessive condition leading to progressive lung disease and often necessitating lung transplantation. Historically, CF has been one of the leading indications for lung transplants in the United States. The advent of CF transmembrane conductance regulator (CFTR) modulators, particularly elexacaftor-tezacaftor-ivacaftor (ETI), has significantly improved clinical outcomes for people with CF (pwCF), offering potential alterations in disease progression and transplantation needs.

Background Acute pulmonary exacerbations (PEx) are associated with increased morbidity and earlier mortality for people living with cystic fibrosis (pwCF). The most common causes of PEx in CF are by b...

findings Studies show that a minority of persons with cystic fibrosis (PwCF) initiating cystic fibrosis transmembrane conductance regulator (CFTR) modulators experience neuropsychiatric AEs includin...

A H3N2 virus - dubbed 'super flu' - is sweeping hospitals in England - and people with one health condition may be more at risk

YouTube video by Vidas Ajenas

The influence of NTM infection in pwCF is still debated, and the extent of their contribution to mortality and morbidity is still questioned. Findings in this study highlight a link between the presen...

YouTube video by Phil Ochs - Topic

AbstractThe study investigates therapeutic strategies for managing chronic Mycobacterium abscessus infections, particularly in people with cystic fibrosis (PWCF) who are ineligible for standard elexacaftor, tezacaftor, ivakaftor (ETI) treatments. Apoptotic body-like liposomes loaded with phosphatidylinositol 5-phosphate (ABL/PI5P) were tested in vitro in M. abscessus-infected macrophages from PWCF as potential treatment. ABL/PI5P reduced intracellular bacterial viability and showed enhanced effects on a M. abscessus clinical strain when combined with amikacin. Notably, ABL/PI5P was effective on macrophages from PWCF not receiving ETI therapy. The findings suggest ABL/PI5P liposomes as a promising alternative or adjunct therapy, especially for those who cannot access ETI treatment, warranting further clinical investigation.

Respiratory viral infections in people with Cystic Fibrosis (pwCF) significantly impact disease progression, and their molecular diagnosis should be part of the recommendations. Sputum, the routinely ...

Rationale: People with cystic fibrosis (pwCF) are living longer with increasing comorbidities.

Background While the widespread initiation of elexacaftor/tezacaftor/ivacaftor (ETI) has led to dramatic clinical improvements among persons with cystic fibrosis (pwCF), little is known about how ET...