Many cellular innovations later used by animals were assembled long before animals evolved.We show that aerobic plasmalogen biosynthesis likely entered eukaryotes early from Myxobacteria, highlighting how bacterial genes shaped the cellular landscape from which animals emerged. 🧬✨ #protistsOnSky
March 18, 2026 at 7:41 AM
Many cellular innovations later used by animals were assembled long before animals evolved.We show that aerobic plasmalogen biosynthesis likely entered eukaryotes early from Myxobacteria, highlighting how bacterial genes shaped the cellular landscape from which animals emerged. 🧬✨ #protistsOnSky
Indeed! Very nice collaboration with @irenedelrey.bsky.social @sebasn1.bsky.social @konsmitsi.bsky.social @jtrinidad13.bsky.social Montse Elias, Padhu & others to decipher the origin of the #plasmalogen biosynthesis pathway. @ibe-barcelona.bsky.social @icreacommunity.bsky.social @csic.es
November 12, 2025 at 7:05 PM
Indeed! Very nice collaboration with @irenedelrey.bsky.social @sebasn1.bsky.social @konsmitsi.bsky.social @jtrinidad13.bsky.social Montse Elias, Padhu & others to decipher the origin of the #plasmalogen biosynthesis pathway. @ibe-barcelona.bsky.social @icreacommunity.bsky.social @csic.es
Check the summary (in Spanish) by @irenedelrey.bsky.social on our work on plasmalogen biosynthesis pathway evolution in eukaryotes. #protistsOnSky
Un pequeño resumen de nuestro artículo publicado en PNAS sobre el origen y evolución de la ruta de biosíntesis de plasmalógenos:
segenetica.es/articulo-en-...
¡Muchas gracias @segenetica.bsky.social !
Trabajo en colaboración con
@multicellgenome.bsky.social y @jtrinidad13.bsky.social
segenetica.es/articulo-en-...
¡Muchas gracias @segenetica.bsky.social !
Trabajo en colaboración con
@multicellgenome.bsky.social y @jtrinidad13.bsky.social
segenetica.es
April 10, 2026 at 6:06 AM
Check the summary (in Spanish) by @irenedelrey.bsky.social on our work on plasmalogen biosynthesis pathway evolution in eukaryotes. #protistsOnSky
After studying the effects of eating sea squirts on mice, scientists found that it may lower brain inflammation and help memory! With more research, we could discover if eating plasmalogen could help reverse aging in humans.
September 28, 2026 at 8:59 PM
After studying the effects of eating sea squirts on mice, scientists found that it may lower brain inflammation and help memory! With more research, we could discover if eating plasmalogen could help reverse aging in humans.
Origin of eukaryotic plasmalogen biosynthesis by horizontal gene transfer from myxobacteria www.pnas.org/doi/abs/10.1... #jcampubs
March 18, 2026 at 5:47 PM
Origin of eukaryotic plasmalogen biosynthesis by horizontal gene transfer from myxobacteria www.pnas.org/doi/abs/10.1... #jcampubs
Origin of eukaryotic plasmalogen biosynthesis by horizontal gene transfer from myxobacteria | PNAS https://www.pnas.org/doi/abs/10.1073/pnas.2529738123?af=R
Origin of eukaryotic plasmalogen biosynthesis by horizontal gene transfer from myxobacteria | PNAS
Plasmalogens are a unique class of glycerophospholipids defined by a distinctive vinyl ether bond. While these lipids are abundant in animals and i...
www.pnas.org
March 19, 2026 at 12:54 AM
Origin of eukaryotic plasmalogen biosynthesis by horizontal gene transfer from myxobacteria | PNAS https://www.pnas.org/doi/abs/10.1073/pnas.2529738123?af=R
📃Scientific paper: Lipid and Transcriptional Regulation in a Parkinson's Disease Mouse Model by Intranasal Vesicular and Hexosomal Plasmalogen‐Based Nanomedicines
Ref.: CCSD;Wiley, 2024
➡️ Continued on ES/IODE
Ref.: CCSD;Wiley, 2024
➡️ Continued on ES/IODE
October 6, 2026 at 12:00 PM
📃Scientific paper: Lipid and Transcriptional Regulation in a Parkinson's Disease Mouse Model by Intranasal Vesicular and Hexosomal Plasmalogen‐Based Nanomedicines
Ref.: CCSD;Wiley, 2024
➡️ Continued on ES/IODE
Ref.: CCSD;Wiley, 2024
➡️ Continued on ES/IODE
✨Our preprint about the evolution and origins of the aerobic plasmalogen biosynthesis pathway is now published in @pnas.org !
🧫Our beloved myxobacteria share more than we think with eukaryotes
Great collaboration with @multicellgenome.bsky.social and @jtrinidad13.bsky.social
🧫Our beloved myxobacteria share more than we think with eukaryotes
Great collaboration with @multicellgenome.bsky.social and @jtrinidad13.bsky.social
📝 New preprint! We trace the origin of the plasmalogen biosynthesis pathway.
🧬 Phylogenetic and functional analyses suggest eukaryotes acquired it via HGT from Myxobacteria, with major lineage-specific differences.
✨Great collaboration between our group at @UMU and @multicellgenome.bsky.social
🧬 Phylogenetic and functional analyses suggest eukaryotes acquired it via HGT from Myxobacteria, with major lineage-specific differences.
✨Great collaboration between our group at @UMU and @multicellgenome.bsky.social
March 17, 2026 at 10:12 PM
✨Our preprint about the evolution and origins of the aerobic plasmalogen biosynthesis pathway is now published in @pnas.org !
🧫Our beloved myxobacteria share more than we think with eukaryotes
Great collaboration with @multicellgenome.bsky.social and @jtrinidad13.bsky.social
🧫Our beloved myxobacteria share more than we think with eukaryotes
Great collaboration with @multicellgenome.bsky.social and @jtrinidad13.bsky.social
SD: "A substance found in edible sea squirts appeared to reverse several signs of aging in older mice. Plasmalogen supplements improved memory and learning, strengthened connections between brain cells, reduced inflammation, and even helped the mice grow thicker, darker hair . . ."
Stanford scientists discover a seafood that can reverse signs of aging
A substance found in edible sea squirts appeared to reverse several signs of aging in older mice. Plasmalogen supplements improved memory and learning, strengthened connections between brain cells, re...
www.sciencedaily.com
September 4, 2026 at 6:54 PM
SD: "A substance found in edible sea squirts appeared to reverse several signs of aging in older mice. Plasmalogen supplements improved memory and learning, strengthened connections between brain cells, reduced inflammation, and even helped the mice grow thicker, darker hair . . ."
Prodrome Science, the store for plasmologens including Glia and Neuro, gave us the affiliate code discount “Falor35” to save 35%! 💸
Glia was used in the @remissionbiome.bsky.social protocol. Go to Prodrome.com and add code “Falor35” at checkout.
Glia was used in the @remissionbiome.bsky.social protocol. Go to Prodrome.com and add code “Falor35” at checkout.
Prodrome | Plasmalogen Supplements for Brain Health
Discover the power of plasmalogen supplements at Prodrome. Real research bringing new hope for people with Dementia, Alzheimer’s, and other brain health.
Prodrome.com
November 25, 2025 at 8:10 PM
Prodrome Science, the store for plasmologens including Glia and Neuro, gave us the affiliate code discount “Falor35” to save 35%! 💸
Glia was used in the @remissionbiome.bsky.social protocol. Go to Prodrome.com and add code “Falor35” at checkout.
Glia was used in the @remissionbiome.bsky.social protocol. Go to Prodrome.com and add code “Falor35” at checkout.
1/ Prodrome Glia (link in comment below) is part of the @remissionbiome.bsky.social protocol. Plasmalogen supplements are some of the most widely used supplements in our community. Already use #prodrome products or plan to discuss with a healthcare team? Save money + give back to our NPO same time!
Prodrome | Plasmalogen Supplements for Brain Health
Discover the power of plasmalogen supplements at Prodrome. Real research bringing new hope for people with Dementia, Alzheimer’s, and other brain health.
prodrome.com
June 18, 2025 at 10:01 PM
1/ Prodrome Glia (link in comment below) is part of the @remissionbiome.bsky.social protocol. Plasmalogen supplements are some of the most widely used supplements in our community. Already use #prodrome products or plan to discuss with a healthcare team? Save money + give back to our NPO same time!
📝 New preprint! We trace the origin of the plasmalogen biosynthesis pathway.
🧬 Phylogenetic and functional analyses suggest eukaryotes acquired it via HGT from Myxobacteria, with major lineage-specific differences.
✨Great collaboration between our group at @UMU and @multicellgenome.bsky.social
🧬 Phylogenetic and functional analyses suggest eukaryotes acquired it via HGT from Myxobacteria, with major lineage-specific differences.
✨Great collaboration between our group at @UMU and @multicellgenome.bsky.social
October 22, 2025 at 9:21 AM
📝 New preprint! We trace the origin of the plasmalogen biosynthesis pathway.
🧬 Phylogenetic and functional analyses suggest eukaryotes acquired it via HGT from Myxobacteria, with major lineage-specific differences.
✨Great collaboration between our group at @UMU and @multicellgenome.bsky.social
🧬 Phylogenetic and functional analyses suggest eukaryotes acquired it via HGT from Myxobacteria, with major lineage-specific differences.
✨Great collaboration between our group at @UMU and @multicellgenome.bsky.social
30% off all Prodrome products prodrome.com
Prodrome | Plasmalogen Supplements for Brain Health
Discover the power of plasmalogen supplements at Prodrome. Real research bringing new hope for people with Dementia, Alzheimer’s, and other brain health.
prodrome.com
November 29, 2024 at 2:47 PM
30% off all Prodrome products prodrome.com
Knockdown of VAPB and ACBD5, tethering proteins that mediate ER-peroxisome contacts, reduced ether lipid and plasmalogen synthesis in iNeurons at day 14. 10/13
February 16, 2026 at 10:28 PM
Knockdown of VAPB and ACBD5, tethering proteins that mediate ER-peroxisome contacts, reduced ether lipid and plasmalogen synthesis in iNeurons at day 14. 10/13
"Three-quarters of the lipids in the deep-sea comb jellies were plasmalogens, a type of curved lipid that is rarer in surface animals..
Plasmalogen lipids are also found in the human brain, and their role in deep-sea membranes could help explain aspects of cell signaling." #ufosky
Plasmalogen lipids are also found in the human brain, and their role in deep-sea membranes could help explain aspects of cell signaling." #ufosky
The Cellular Secret to Resisting the Pressure of the Deep Sea | Quanta Magazine
Cell membranes from comb jellies reveal a new kind of adaptation to the deep sea: curvy lipids that conform to an ideal shape under pressure.
www.quantamagazine.org
February 8, 2025 at 1:13 PM
"Three-quarters of the lipids in the deep-sea comb jellies were plasmalogens, a type of curved lipid that is rarer in surface animals..
Plasmalogen lipids are also found in the human brain, and their role in deep-sea membranes could help explain aspects of cell signaling." #ufosky
Plasmalogen lipids are also found in the human brain, and their role in deep-sea membranes could help explain aspects of cell signaling." #ufosky
Higher omega-3 DHA-plasmalogen phospholipid levels across early life mediate the benefits of maternal healthy diet and breastfeeding on infant neurocognition https://www.medrxiv.org/content/10.64898/2026.03.22.26348566v1
March 24, 2026 at 10:55 PM
Higher omega-3 DHA-plasmalogen phospholipid levels across early life mediate the benefits of maternal healthy diet and breastfeeding on infant neurocognition https://www.medrxiv.org/content/10.64898/2026.03.22.26348566v1
1/ Prodrome Glia is part of the @remissionbiome protocol. Plasmalogen supplements are widely used in our community. If you already use Prodrome products or plan to discuss with your healthcare team, you can save money and give back to our non-profit at the same time!
May 29, 2025 at 11:30 PM
1/ Prodrome Glia is part of the @remissionbiome protocol. Plasmalogen supplements are widely used in our community. If you already use Prodrome products or plan to discuss with your healthcare team, you can save money and give back to our non-profit at the same time!
🎉 Excited to share that our ARUK Pilot Grant has been funded! 🚀
Our project will explore plasmalogen lipid function in human iPSC-neurons to better understand synaptic dysfunction in Alzheimer’s Disease.
🧠💡 Stay tuned for updates!
@alzheimersresearchuk.org #NeuroLipidomics #Alzheimers #Plasmalogen
Our project will explore plasmalogen lipid function in human iPSC-neurons to better understand synaptic dysfunction in Alzheimer’s Disease.
🧠💡 Stay tuned for updates!
@alzheimersresearchuk.org #NeuroLipidomics #Alzheimers #Plasmalogen
April 3, 2025 at 1:47 PM
🎉 Excited to share that our ARUK Pilot Grant has been funded! 🚀
Our project will explore plasmalogen lipid function in human iPSC-neurons to better understand synaptic dysfunction in Alzheimer’s Disease.
🧠💡 Stay tuned for updates!
@alzheimersresearchuk.org #NeuroLipidomics #Alzheimers #Plasmalogen
Our project will explore plasmalogen lipid function in human iPSC-neurons to better understand synaptic dysfunction in Alzheimer’s Disease.
🧠💡 Stay tuned for updates!
@alzheimersresearchuk.org #NeuroLipidomics #Alzheimers #Plasmalogen
Origin of Eukaryotic Plasmalogen Biosynthesis by Horizontal Gene Transfer from Myxobacteria https://www.biorxiv.org/content/10.1101/2025.10.10.681575v1
October 11, 2025 at 1:32 AM
Origin of Eukaryotic Plasmalogen Biosynthesis by Horizontal Gene Transfer from Myxobacteria https://www.biorxiv.org/content/10.1101/2025.10.10.681575v1
- in the brainstem & other stress-responsive brain regions leads to oxidative & nitrosative stress, further promoting immune and metabolic dysfunction
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Chronic inflammation, neuroglial dysfunction, and plasmalogen deficiency as a new pathobiological hypothesis addressing the overlap between post-COVID-19 symptoms and myalgic encephalomyelitis/chronic...
After five waves of coronavirus disease 2019 (COVID-19) outbreaks, it has been recognized that a significant portion of the affected individuals devel…
www.sciencedirect.com
November 17, 2025 at 8:05 AM
- in the brainstem & other stress-responsive brain regions leads to oxidative & nitrosative stress, further promoting immune and metabolic dysfunction
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
