■1977年. 1974年に始まった1隻の戦艦の物語は1977年の夏に社会現象とも言うべきビッグバンを引き起こす。そしてそれは今に至るアニメブームの発端となった。 奇しくも、その戦艦の物語に登場する筈であった隻眼の男の物語もまた、同じ1977年の1月にマンガ連載開始となっていた。 巨大な力が働いたように全てが猛然と動き出した。同年のクリスマスには『交響組曲 宇宙戦艦ヤマト』が発表される。 その19...

We downloaded all kps-positive E. coli from a published, searchable collection of 661,000 bacterial assemblies14 and supplemented them with published ExPEC genomic studies15,16,17,18,19,20,21,22. Genomes with a known phenotypic K type were sourced for 24 different K types from GenBank, the National Collection of Type Cultures (NCTC) project23 and EnteroBase24. From the subsequent 18,185 kps-positive E. coli genomes, we extracted and annotated the K locus and observed 90 G2 (n = 68) and G3 (n = 22) ABC transporter-dependent K loci, based on unique K locus gene presence and absence patterns using Panaroo25. These unique K loci were used to create a GenBank reference database, compatible with the species-agnostic bacterial capsular locus typing tool Kaptive26, to allow in silico G2 and G3 E. coli K typing from assemblies. Of the known G2 and G3 phenotypic K types, 80% are represented here by phenotype–genotype paired data, yet known phenotypes only represent 34% of the 90 K loci observed to have unique capsular gene sets. Furthermore, for 11 K loci with no known phenotype observed in Norwegian BSIs, we confirmed a K+ phenotype, with a positive precipitate on reaction with Cetavlon, and found them to be negative for known K antigens, representing putatively...