We introduce #ProxiCapture, an affinity-proteomics platform to map degrader-induced interactions in native cell & tissue lysates. We uncover a context-dependent “glueable” proteome and a scalable route to accelerate molecular glue discovery 🤗
@ibc2-gu.bsky.social @goetheuni.bsky.social

ProxiCapture Reveals Context-Dependent CRBN Interactore Landscape of Molecular Glue Degraders https://www.biorxiv.org/content/10.64898/2026.01.05.697692v1

PXD073192 🚨

ProxiCapture enables proteomics-wide identification of degrader-dependent CRBN-protein interactions across diverse biological contexts.

🚨 New dataset alert! 🚨

ProxiCapture Reveals Context-Dependent CRBN Interactore Landscape of Molecular Glue Degraders https://www.biorxiv.org/content/10.64898/2026.01.05.697692v1

PXD070945 🚨

ProxiCapture enables proteome-wide identification of degrader-dependent CRBN-protein interactions across diverse biological contexts.

🚨 New dataset alert! 🚨