Oral cephalosporins for pyelonephritis?!
🆕️⚡️⚡️COPY-ED
Multicenter, retrospective study
N=851
No difference in 14-day pyelonephritis treatment failure for oral cephalosporins* vs FQ/TMP-SMX for outpatient pyelonephritis in the ED #idsky #medsky
* Mostly cephalexin
www.sciencedirect.com/science/arti...
🆕️⚡️⚡️COPY-ED
Multicenter, retrospective study
N=851
No difference in 14-day pyelonephritis treatment failure for oral cephalosporins* vs FQ/TMP-SMX for outpatient pyelonephritis in the ED #idsky #medsky
* Mostly cephalexin
www.sciencedirect.com/science/arti...
November 25, 2024 at 12:42 PM
Oral cephalosporins for pyelonephritis?!
🆕️⚡️⚡️COPY-ED
Multicenter, retrospective study
N=851
No difference in 14-day pyelonephritis treatment failure for oral cephalosporins* vs FQ/TMP-SMX for outpatient pyelonephritis in the ED #idsky #medsky
* Mostly cephalexin
www.sciencedirect.com/science/arti...
🆕️⚡️⚡️COPY-ED
Multicenter, retrospective study
N=851
No difference in 14-day pyelonephritis treatment failure for oral cephalosporins* vs FQ/TMP-SMX for outpatient pyelonephritis in the ED #idsky #medsky
* Mostly cephalexin
www.sciencedirect.com/science/arti...
2-jähriger kommt mit dem Papa in die Praxis. Seit 5 Tagen Fieber. Kein Husten, kein Schnupfen. Urin riecht streng.
Körperliche Untersuchung unauffällig. Beutelurin klappt nicht. CRP über 65mg/l. Eingewiesen mit Verdacht auf Pyelonephritis.
Diagnose: Pyelonephritis mit Megaureter beidseits.
Körperliche Untersuchung unauffällig. Beutelurin klappt nicht. CRP über 65mg/l. Eingewiesen mit Verdacht auf Pyelonephritis.
Diagnose: Pyelonephritis mit Megaureter beidseits.
March 10, 2025 at 3:50 PM
2-jähriger kommt mit dem Papa in die Praxis. Seit 5 Tagen Fieber. Kein Husten, kein Schnupfen. Urin riecht streng.
Körperliche Untersuchung unauffällig. Beutelurin klappt nicht. CRP über 65mg/l. Eingewiesen mit Verdacht auf Pyelonephritis.
Diagnose: Pyelonephritis mit Megaureter beidseits.
Körperliche Untersuchung unauffällig. Beutelurin klappt nicht. CRP über 65mg/l. Eingewiesen mit Verdacht auf Pyelonephritis.
Diagnose: Pyelonephritis mit Megaureter beidseits.
Diagnosis: pyelonephritis/urosepsis
That was fun. Good times… I’m still sweating buckets.
That was fun. Good times… I’m still sweating buckets.
February 8, 2025 at 9:28 PM
Diagnosis: pyelonephritis/urosepsis
That was fun. Good times… I’m still sweating buckets.
That was fun. Good times… I’m still sweating buckets.
6/ "Filling the bottles is a very tedious task. The water doesn't hit the plastic with a vigorous stream; no... it's the sluggish flow of a coyote with pyelonephritis. This entire undertaking requires stoic patience, good hearing, and an internal clock.
March 19, 2026 at 8:05 AM
6/ "Filling the bottles is a very tedious task. The water doesn't hit the plastic with a vigorous stream; no... it's the sluggish flow of a coyote with pyelonephritis. This entire undertaking requires stoic patience, good hearing, and an internal clock.
Hi, I’m bilateral pyelonephritis.
January 2, 2026 at 12:08 AM
Hi, I’m bilateral pyelonephritis.
New EMPHARMNET study-COPY-ED
Worried about cephalosporins in pyelonephritis? Fret not!
🧪 No difference in 14-day pyelonephritis treatment failure 💊for Ceph (n=647) vs FQ/TMP-SMX (n=204)
Love working with smart people to do cool things!
#MedSky #EMSky #IDSky
www.sciencedirect.com/science/arti...
Cephalosporins for Outpatient Pyelonephritis in the Emergency Department: COPY-ED Study
The primary objective of our study was to compare the effectiveness of oral cephalosporins versus fluroquinolones and trimethoprim/sulfamethoxazole (T…
www.sciencedirect.com
November 21, 2024 at 1:14 AM
New EMPHARMNET study-COPY-ED
Worried about cephalosporins in pyelonephritis? Fret not!
🧪 No difference in 14-day pyelonephritis treatment failure 💊for Ceph (n=647) vs FQ/TMP-SMX (n=204)
Love working with smart people to do cool things!
#MedSky #EMSky #IDSky
www.sciencedirect.com/science/arti...
The ALLIUM trial
Novel antibiotic cefepime -enmetazobactam is non inferior vs piperacillin-tazobactam for pyelonephritis
#escmidglobal2026
Novel antibiotic cefepime -enmetazobactam is non inferior vs piperacillin-tazobactam for pyelonephritis
#escmidglobal2026
April 18, 2026 at 9:46 AM
The ALLIUM trial
Novel antibiotic cefepime -enmetazobactam is non inferior vs piperacillin-tazobactam for pyelonephritis
#escmidglobal2026
Novel antibiotic cefepime -enmetazobactam is non inferior vs piperacillin-tazobactam for pyelonephritis
#escmidglobal2026
Important letter in @bsacandjac.bsky.social on use of cefalexin in treating pyelonephritis.
Is it effective? What's the right dose? 🤷♂️
Key quote... 👉 "Critically, there are no EUCAST breakpoints for cefalexin for systemic infection including acute pyelonephritis."
#IDSky #ClinMicro #AMR #UTISky
Is it effective? What's the right dose? 🤷♂️
Key quote... 👉 "Critically, there are no EUCAST breakpoints for cefalexin for systemic infection including acute pyelonephritis."
#IDSky #ClinMicro #AMR #UTISky
Cefalexin use in UK acute pyelonephritis practice: unaddressed challenges in dosing, breakpoints and clinical evidence
Dear Editor in Chief,
academic.oup.com
March 2, 2026 at 9:25 AM
Important letter in @bsacandjac.bsky.social on use of cefalexin in treating pyelonephritis.
Is it effective? What's the right dose? 🤷♂️
Key quote... 👉 "Critically, there are no EUCAST breakpoints for cefalexin for systemic infection including acute pyelonephritis."
#IDSky #ClinMicro #AMR #UTISky
Is it effective? What's the right dose? 🤷♂️
Key quote... 👉 "Critically, there are no EUCAST breakpoints for cefalexin for systemic infection including acute pyelonephritis."
#IDSky #ClinMicro #AMR #UTISky
As a medical health professional, I feel it's my job to make sure everybody knows that is not where good dick goes....unless you want pyelonephritis or somethin
April 17, 2026 at 3:02 AM
As a medical health professional, I feel it's my job to make sure everybody knows that is not where good dick goes....unless you want pyelonephritis or somethin
After a month of pain and pyelonephritis, I can finally get back to the pool. Let’s see how long today goes. Taking it easy.
January 9, 2025 at 1:02 AM
After a month of pain and pyelonephritis, I can finally get back to the pool. Let’s see how long today goes. Taking it easy.
Phase 3 trial for oral cUTI antibiotic stopped early for efficacy
An interim analysis of trial data finds that tebipenem HBr met its primary efficacy end point in patients with complicated urinary tract infections, including pyelonephritis.
www.cidrap.umn.edu/a...
An interim analysis of trial data finds that tebipenem HBr met its primary efficacy end point in patients with complicated urinary tract infections, including pyelonephritis.
www.cidrap.umn.edu/a...
May 29, 2025 at 9:02 PM
Phase 3 trial for oral cUTI antibiotic stopped early for efficacy
An interim analysis of trial data finds that tebipenem HBr met its primary efficacy end point in patients with complicated urinary tract infections, including pyelonephritis.
www.cidrap.umn.edu/a...
An interim analysis of trial data finds that tebipenem HBr met its primary efficacy end point in patients with complicated urinary tract infections, including pyelonephritis.
www.cidrap.umn.edu/a...
Staph epidermidis + urine culture not always contaminant. KTx Bx with rising sCr. Patchy neutrophilic casts and interstitial inflammation suggestion of acute pyelonephritis. #renalpath #nephsky #pathsky
February 8, 2025 at 12:44 AM
Staph epidermidis + urine culture not always contaminant. KTx Bx with rising sCr. Patchy neutrophilic casts and interstitial inflammation suggestion of acute pyelonephritis. #renalpath #nephsky #pathsky
i was told my blood was type O but they told me I can't donate because i had pyelonephritis as a kid
July 29, 2026 at 12:58 PM
i was told my blood was type O but they told me I can't donate because i had pyelonephritis as a kid
Hey, disseminated pyelonephritis :)
Hi, Im meningitis I had as a baby. Hi, Im fell off a zip line and landed from 20 feet in the air on my back. Hi, im pancreatitis. Hi, im a nine inch ovarian cyst. Hi, i-
Introduce yourself as what almost killed you:
Hi, I'm Lou
Hi, I'm Lou
August 14, 2026 at 11:53 AM
Hey, disseminated pyelonephritis :)
I am slowly recovering from pyelonephritis. Feels good to finally start feeling like a human again...
May 13, 2026 at 8:55 AM
I am slowly recovering from pyelonephritis. Feels good to finally start feeling like a human again...
Okay, Pat. sie haben Recht! Ich habe mich geirrt, es ist eine Pyelonephritis😁
November 17, 2023 at 5:58 PM
Okay, Pat. sie haben Recht! Ich habe mich geirrt, es ist eine Pyelonephritis😁
Patient with acute kidney injury following vancomycin treatment for pyelonephritis. Numerous unusual casts (no LC restriction, myo/hemoglobin and chromo negative). EM shows mixture of uromodulin protein and precipitate. C/W vancomycin cast nephropathy. #renalpath #pathsky #nephsky
January 8, 2025 at 1:46 PM
Patient with acute kidney injury following vancomycin treatment for pyelonephritis. Numerous unusual casts (no LC restriction, myo/hemoglobin and chromo negative). EM shows mixture of uromodulin protein and precipitate. C/W vancomycin cast nephropathy. #renalpath #pathsky #nephsky
Nitrofurantoin prescribed to a friend with pyelonephritis?!🫘
Not on my watch. Activate ID pharmacist!!🦸🏻♀️
#PKMatters #UTIsky #IDsky #Pharmsky
Not on my watch. Activate ID pharmacist!!🦸🏻♀️
#PKMatters #UTIsky #IDsky #Pharmsky
a man in a cape stands in front of a batman symbol
Alt: Batman signal in the night sky
media.tenor.com
October 25, 2025 at 6:43 PM
Nitrofurantoin prescribed to a friend with pyelonephritis?!🫘
Not on my watch. Activate ID pharmacist!!🦸🏻♀️
#PKMatters #UTIsky #IDsky #Pharmsky
Not on my watch. Activate ID pharmacist!!🦸🏻♀️
#PKMatters #UTIsky #IDsky #Pharmsky
Leukocyte (neutrophil) casts can be found in pyelonephritis, interstitial nephritis and glomerulonephritis. But in this case, there’s only one clear possibility. Can you tell? #UrinarySediment #UrineMicroscopy #PisseProphet
December 28, 2024 at 2:58 AM
Leukocyte (neutrophil) casts can be found in pyelonephritis, interstitial nephritis and glomerulonephritis. But in this case, there’s only one clear possibility. Can you tell? #UrinarySediment #UrineMicroscopy #PisseProphet
🌟 ABX Pearl of the Day: ertapenem hypoalbuminemia
❓ Q: My ICU patient with hypoalbuminemia has ESBL E. coli pyelonephritis, resistant to PO abx. He improved (afeb, WBC WNL, off pressors) after 3d of meropenem. Should I avoid narrowing to ertapenem?
#IDsky #medsky #meded #pharmsky #skyRX #AMSsky
❓ Q: My ICU patient with hypoalbuminemia has ESBL E. coli pyelonephritis, resistant to PO abx. He improved (afeb, WBC WNL, off pressors) after 3d of meropenem. Should I avoid narrowing to ertapenem?
#IDsky #medsky #meded #pharmsky #skyRX #AMSsky
July 2, 2025 at 3:23 PM
In patients with cUTI (including acute pyelonephritis) treated initially with parenteral therapy who are clinically improving,able to take oral medication,and for whom an effective oral option is available,we suggest transitioning to oral antibiotics rather than continuing IV Abx #idsky #EMIMCC
🔥A sneak peak on the upcoming IDSA guidelines for cUTI🔥
Public Comment: IDSA Guideline on Management and Treatment of Complicated Urinary Tract Infections
So it's still not published yet ! #idsky #medsky #utisky
www.idsociety.org/practice-gui...
Public Comment: IDSA Guideline on Management and Treatment of Complicated Urinary Tract Infections
So it's still not published yet ! #idsky #medsky #utisky
www.idsociety.org/practice-gui...
February 19, 2025 at 10:13 PM
Yes, feel better! And don’t hesitate to go again if you don’t start to feel better or actually feel sicker. (Flank pain, fever etc.) Pyelonephritis can develop from untreated UTI and is a bit more dangerous.
May 5, 2025 at 10:27 PM
Yes, feel better! And don’t hesitate to go again if you don’t start to feel better or actually feel sicker. (Flank pain, fever etc.) Pyelonephritis can develop from untreated UTI and is a bit more dangerous.
Today I learned about xanthogranulomatous pyelonephritis
April 3, 2026 at 7:07 PM
Today I learned about xanthogranulomatous pyelonephritis
Dr. Keintz is interviewed in this @contagionlive.bsky.social article about her most recent paper in @ashejournal.bsky.social
Read the paper here:
www.cambridge.org/core/journal...
@bryanidpharmd.bsky.social #IDSky #UTISky
Read the paper here:
www.cambridge.org/core/journal...
@bryanidpharmd.bsky.social #IDSky #UTISky
January 28, 2025 at 8:33 PM
Dr. Keintz is interviewed in this @contagionlive.bsky.social article about her most recent paper in @ashejournal.bsky.social
Read the paper here:
www.cambridge.org/core/journal...
@bryanidpharmd.bsky.social #IDSky #UTISky
Read the paper here:
www.cambridge.org/core/journal...
@bryanidpharmd.bsky.social #IDSky #UTISky