Le syndrome ReNU, la nouvelle maladie rare qu'on avait pas vu venir
Troubles du développement : le syndrome ReNU, la nouvelle maladie rare qu'on avait pas vu venir
l.whatsupdoc-lemag.fr
October 1, 2026 at 1:25 PM
Le syndrome ReNU, la nouvelle maladie rare qu'on avait pas vu venir
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October 1, 2026 at 1:05 AM
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September 30, 2026 at 7:07 PM
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Our intention, was to investigate whether a small number of sites could be used as a robust biomarker to support therapeutic development. We were super excited therefore to see the 6-site signature port beautifully to a patient-derived iPSC neuronal model across differentiation 🧠
3/4
3/4
September 30, 2026 at 11:22 AM
Our intention, was to investigate whether a small number of sites could be used as a robust biomarker to support therapeutic development. We were super excited therefore to see the 6-site signature port beautifully to a patient-derived iPSC neuronal model across differentiation 🧠
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3/4
The 6-site signature, developed using individuals w/ the recurrent n.64_65insT variant, is specific to variants in the T-loop, one of 2 structures in U4 implicated in ReNU syndrome. We find evidence of Stem III specific events.
This suggests 2 molecularly distinct sub-types of ReNU syndrome 🤯
2/4
This suggests 2 molecularly distinct sub-types of ReNU syndrome 🤯
2/4
September 30, 2026 at 11:22 AM
The 6-site signature, developed using individuals w/ the recurrent n.64_65insT variant, is specific to variants in the T-loop, one of 2 structures in U4 implicated in ReNU syndrome. We find evidence of Stem III specific events.
This suggests 2 molecularly distinct sub-types of ReNU syndrome 🤯
2/4
This suggests 2 molecularly distinct sub-types of ReNU syndrome 🤯
2/4
Excited to share our new preprint "A cross-tissue splicing signature as a quantitative biomarker for ReNU syndrome"
tinyurl.com/RENUsig
Led by super⭐ duo @ruebenadawes.bsky.social @alexblakes.bsky.social
We show that just 6 alternative 5'splice site events perfectly predict ReNU syndrome 🧬
🧵 1/4
tinyurl.com/RENUsig
Led by super⭐ duo @ruebenadawes.bsky.social @alexblakes.bsky.social
We show that just 6 alternative 5'splice site events perfectly predict ReNU syndrome 🧬
🧵 1/4
September 30, 2026 at 11:22 AM
Excited to share our new preprint "A cross-tissue splicing signature as a quantitative biomarker for ReNU syndrome"
tinyurl.com/RENUsig
Led by super⭐ duo @ruebenadawes.bsky.social @alexblakes.bsky.social
We show that just 6 alternative 5'splice site events perfectly predict ReNU syndrome 🧬
🧵 1/4
tinyurl.com/RENUsig
Led by super⭐ duo @ruebenadawes.bsky.social @alexblakes.bsky.social
We show that just 6 alternative 5'splice site events perfectly predict ReNU syndrome 🧬
🧵 1/4
A cross-tissue splicing signature as a quantitative biomarker for ReNU syndrome #RareDisease #Genetics www.medrxiv.org/content/10.6...
September 29, 2026 at 6:51 PM
A cross-tissue splicing signature as a quantitative biomarker for ReNU syndrome #RareDisease #Genetics www.medrxiv.org/content/10.6...
Can a molecular fingerprint with zero false positives in 5,984 controls solve the diagnostic challenge for a severe neurodevelopmental disorder? A new medRxiv preprint maps a highly specific splicing signature for ReNU syndrome.
A six-site RNA signature detects ReNU syndrome
A new molecular signature could finally give drug developers a reliable way to measure treatments for a severe neurodevelopmental disorder.
yesilscience.com
September 29, 2026 at 5:01 PM
Can a molecular fingerprint with zero false positives in 5,984 controls solve the diagnostic challenge for a severe neurodevelopmental disorder? A new medRxiv preprint maps a highly specific splicing signature for ReNU syndrome.
Jean Renu - deeply suspicious, those Speedos in Big Blue!
September 29, 2026 at 8:06 AM
Jean Renu - deeply suspicious, those Speedos in Big Blue!
On the Secular Evolution of Inclinations Among the Classical Belt TNOs
https://arxiv.org/pdf/2609.33080
Dallin Spencer, Darin Ragozzine, Kat Volk, Renu Malhotra.
https://arxiv.org/pdf/2609.33080
Dallin Spencer, Darin Ragozzine, Kat Volk, Renu Malhotra.
https://arxiv.org/abs/2609.33080
arXiv abstract link
arxiv.org
September 29, 2026 at 7:32 AM
On the Secular Evolution of Inclinations Among the Classical Belt TNOs
https://arxiv.org/pdf/2609.33080
Dallin Spencer, Darin Ragozzine, Kat Volk, Renu Malhotra.
https://arxiv.org/pdf/2609.33080
Dallin Spencer, Darin Ragozzine, Kat Volk, Renu Malhotra.
Dallin Spencer, Darin Ragozzine, Kat Volk, Renu Malhotra: On the Secular Evolution of Inclinations Among the Classical Belt TNOs https://arxiv.org/abs/2609.33080 https://arxiv.org/pdf/2609.33080 https://arxiv.org/html/2609.33080
September 29, 2026 at 6:51 AM
Dallin Spencer, Darin Ragozzine, Kat Volk, Renu Malhotra: On the Secular Evolution of Inclinations Among the Classical Belt TNOs https://arxiv.org/abs/2609.33080 https://arxiv.org/pdf/2609.33080 https://arxiv.org/html/2609.33080
📰 New article by Sangmin Woo, Bharathi Srinivasan, Haibo Ding, Jonathan Buck, Renu Rozera, Shruthi Rajoli, Vinayak Arannil, Visakh Madathil
Evaluate skill-equipped agents with Strands Evals and Amazon Bedrock AgentCore
#AWS #AI #MachineLearning
Evaluate skill-equipped agents with Strands Evals and Amazon Bedrock AgentCore
#AWS #AI #MachineLearning
Evaluate skill-equipped agents with Strands Evals and Amazon Bedrock AgentCore
Skills let you encode domain-specific procedures as reusable, portable instructions for agents, but a fluent answer doesn’t prove the agent picked the right skill or followed it. Learn how to measure skill selection and instruction following with Strands Evals and Amazon Bedrock AgentCore Evaluations.
aws.amazon.com
September 22, 2026 at 5:21 PM
📰 New article by Sangmin Woo, Bharathi Srinivasan, Haibo Ding, Jonathan Buck, Renu Rozera, Shruthi Rajoli, Vinayak Arannil, Visakh Madathil
Evaluate skill-equipped agents with Strands Evals and Amazon Bedrock AgentCore
#AWS #AI #MachineLearning
Evaluate skill-equipped agents with Strands Evals and Amazon Bedrock AgentCore
#AWS #AI #MachineLearning
She also acknowledges, reluctantly, that the best public bathrooms are maintained by Business Improvement Districts. The Bryant Square Park bathroom, for example. www.youtube.com/watch?v=0Rh9...
Beautiful Good Looking Public Restroom in NewYork Bryant Park
YouTube video by Journey of My Life by Renu Gihar
www.youtube.com
September 21, 2026 at 9:58 PM
She also acknowledges, reluctantly, that the best public bathrooms are maintained by Business Improvement Districts. The Bryant Square Park bathroom, for example. www.youtube.com/watch?v=0Rh9...
The irony is that Renu and I went to Yuba City - Nagar Kirtan Frstival - largest gathering of Sikh’s outside of India. In 2023 - many Trump supporters. Lots of pro Trump posters.
September 18, 2026 at 6:57 PM
The irony is that Renu and I went to Yuba City - Nagar Kirtan Frstival - largest gathering of Sikh’s outside of India. In 2023 - many Trump supporters. Lots of pro Trump posters.
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September 17, 2026 at 12:56 AM
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4/
The fun starts today at 17 UTC with TTC's Tuesday game: Rumble Royale
The prize for he winner is "Into My Cells #1" by Samantha E. Harvey [SEH], donated to TTC by Renu aka @Rae5555
🔗 objkt.com/tokens/KT1RJ...
StrongerTogether #Tezos 🎁 Gift Week'26
🧵⬇️
The fun starts today at 17 UTC with TTC's Tuesday game: Rumble Royale
The prize for he winner is "Into My Cells #1" by Samantha E. Harvey [SEH], donated to TTC by Renu aka @Rae5555
🔗 objkt.com/tokens/KT1RJ...
StrongerTogether #Tezos 🎁 Gift Week'26
🧵⬇️
September 15, 2026 at 9:01 AM
4/
The fun starts today at 17 UTC with TTC's Tuesday game: Rumble Royale
The prize for he winner is "Into My Cells #1" by Samantha E. Harvey [SEH], donated to TTC by Renu aka @Rae5555
🔗 objkt.com/tokens/KT1RJ...
StrongerTogether #Tezos 🎁 Gift Week'26
🧵⬇️
The fun starts today at 17 UTC with TTC's Tuesday game: Rumble Royale
The prize for he winner is "Into My Cells #1" by Samantha E. Harvey [SEH], donated to TTC by Renu aka @Rae5555
🔗 objkt.com/tokens/KT1RJ...
StrongerTogether #Tezos 🎁 Gift Week'26
🧵⬇️
DeUnemploy yourself today.
Semantic search: "licensed electrician, commercial work"
Licensed Field Electrician
Renu Energy Solutions · Charlotte, NC, USA
10,687 matching in the US — 4,450,859 worldwide.
https://deunemployment.com/job/32f3f7a63ec1?v=2
Semantic search: "licensed electrician, commercial work"
Licensed Field Electrician
Renu Energy Solutions · Charlotte, NC, USA
10,687 matching in the US — 4,450,859 worldwide.
https://deunemployment.com/job/32f3f7a63ec1?v=2
Licensed Field Electrician
Matched by semantic search "licensed electrician, commercial work". 4,450,859 live postings.
deunemployment.com
September 12, 2026 at 2:00 AM
DeUnemploy yourself today.
Semantic search: "licensed electrician, commercial work"
Licensed Field Electrician
Renu Energy Solutions · Charlotte, NC, USA
10,687 matching in the US — 4,450,859 worldwide.
https://deunemployment.com/job/32f3f7a63ec1?v=2
Semantic search: "licensed electrician, commercial work"
Licensed Field Electrician
Renu Energy Solutions · Charlotte, NC, USA
10,687 matching in the US — 4,450,859 worldwide.
https://deunemployment.com/job/32f3f7a63ec1?v=2
BUT WAIT
THERE'S MORE
look at Renu Rewa!
THERE'S MORE
look at Renu Rewa!
September 9, 2026 at 3:14 AM
BUT WAIT
THERE'S MORE
look at Renu Rewa!
THERE'S MORE
look at Renu Rewa!
TD Bank Group shakes up leadership to consolidate tech, AI, and commercial strategy
Vlad Shpilsky, Renu Gupta, and Paul Whitehead have been appointed to newly consolidated senior executive roles
www.fintechfutures.com/job-cuts-new...
#FinTech #FinServ #Banking
Vlad Shpilsky, Renu Gupta, and Paul Whitehead have been appointed to newly consolidated senior executive roles
www.fintechfutures.com/job-cuts-new...
#FinTech #FinServ #Banking
TD Bank shakes up leadership to unify tech, AI, and strategy
TD Bank Group in major executive restructuring to unify core commercial strategies, global technology infrastructure, and AI initiatives - read more here.
www.fintechfutures.com
September 8, 2026 at 8:30 PM
TD Bank Group shakes up leadership to consolidate tech, AI, and commercial strategy
Vlad Shpilsky, Renu Gupta, and Paul Whitehead have been appointed to newly consolidated senior executive roles
www.fintechfutures.com/job-cuts-new...
#FinTech #FinServ #Banking
Vlad Shpilsky, Renu Gupta, and Paul Whitehead have been appointed to newly consolidated senior executive roles
www.fintechfutures.com/job-cuts-new...
#FinTech #FinServ #Banking
Thanks Renu! Thoughtful policy often is hard and messy. This one was a tricky needle to thread.
September 8, 2026 at 6:32 PM
Thanks Renu! Thoughtful policy often is hard and messy. This one was a tricky needle to thread.
