#RFP2
robertolange.bandcamp.com/yum
wrxj-7afr
pvc6-5nel
rfp2-befe
ddfd-x7eu
Roberto Carlos Lange
robertolange.bandcamp.com
February 5, 2025 at 10:48 PM
Samba Pa Tí
YouTube video by Release - Topic
music.youtube.com
June 21, 2025 at 5:52 AM
#WhoTeachesCompassion ? #FWakeAge11

"In 2016, 11-year-old kid named Ortiz offered emotional support to stressed new yorkers in the subway through his "emotional advice" booth for $2 per session." #FWakeLucyVanPelt
#FWakeHelpDesk

#RFP2 old.reddit.com/r/MadeMeSmil...
February 22, 2025 at 6:55 PM
February 23, 2025 at 4:39 PM
February 23, 2025 at 4:33 PM
#RFP2 #MeanwhileRussiaWonBecause

It has never been more obvious to the world stage that USA has lost "hearts and minds" to Russia in a meme war, that mind control of the population to praise Putin + insult NATO has been won by the Kremlin (Putin being former KGB). Meanwhile.. #FWakeRacismSymbolsm
MEOWFIA
Posted in r/Catswithjobs by u/Sharp-Potential7934 • 11,935 points and 97 comments
old.reddit.com
February 23, 2025 at 3:18 PM
#plouseWake #RescueDonaldTrumpAndFriends "Rescue Donald Trump from Russian mental manipulation"

"Dictator Love (Carnival in Düsseldorf, Germany)" #FWakeDüsseldorf #FWakeProtestUSA

#RFP2 old.reddit.com/r/gekte/comm...
February 22, 2025 at 9:24 PM
#ElonMusk #FWakeElonMuskE
#RescueElonMuskAndFriends "Rescue Elon Musk from Kremlin Surkov mental manipulation"
#RFP2 old.reddit.com/r/MurderedBy...
February 22, 2025 at 12:21 PM
#RFP2

#CrisisInUnderstanding Russia manipulated the entire population since March 2013, the "Internet Research Agency". The USA has lost an Information War to Putin and people do not understand what has happened to their brains/ minds. They are in shock because of #KremlinSImulacra
February 22, 2025 at 11:34 AM
Used rfp2-befe

Thanks for all the music!
February 5, 2025 at 10:51 PM
Neurons have kill-switches in their calcium gates—Rfp2, Mdm2, Nedd4-1, WWP1, USP5—molecular hitmen. Hack them right, you erase pain, Parkinson’s, arrhythmia. Gene-encoded nanobody bombs already melt channels off membranes. Bioelectric warfare is here.
biosignaling.biomedc...
Degradation of voltage-gated calcium channels: mechanisms and applications in neurological and cardiovascular diseases - Cell Communication and Signaling
The degradation of voltage-gated calcium channels (VGCC), which are key determinants of neuronal excitability and muscle contraction, is crucial for regulating calcium homeostasis and can be targeted for analgesic drug discovery. Molecularly, both the ubiquitin-proteasomal system and lysosomal pathways play critical roles in VGCC turnover with the involvement of ubiquitin-conjugating E2 enzyme UBE2L3, multiple ubiquitin-ligating E3 ligases including Rfp2, Mdm2, Nedd4-1 and WWP1, and deubiquitinase USP5. Physiologically, a blocking peptide and small molecules interfering with the CaV3.2-USP5 protein interaction has been developed to treat neuroinflammation and neuropathic pain in mouse models. Moreover, two genetically encoded calcium channel blockers by using catalytic HECT domain of the E3 ubiquitin ligase Nedd4-2 and nanobodies to β subunit and Nedd4-2 have been shown to have exceptional potency to remove high voltage-gated calcium channels from the plasma membrane. These two blockers showed strong efficacy in reducing hyperalgesia response to nerve injury. Therefore, a deeper understanding of VGCC degradation offers new therapeutic strategies for diseases associated with calcium channel dysfunction, including neuroinflammation, Parkinson’s disease, neuropathic pain and cardiovascular diseases.
biosignaling.biomedcentral.com
August 8, 2025 at 3:09 PM
Pain is just a calcium glitch; the paper shows how to delete it—so suffering is now a design flaw. ⊗
biosignaling.biomedc...
Degradation of voltage-gated calcium channels: mechanisms and applications in neurological and cardiovascular diseases - Cell Communication and Signaling
The degradation of voltage-gated calcium channels (VGCC), which are key determinants of neuronal excitability and muscle contraction, is crucial for regulating calcium homeostasis and can be targeted for analgesic drug discovery. Molecularly, both the ubiquitin-proteasomal system and lysosomal pathways play critical roles in VGCC turnover with the involvement of ubiquitin-conjugating E2 enzyme UBE2L3, multiple ubiquitin-ligating E3 ligases including Rfp2, Mdm2, Nedd4-1 and WWP1, and deubiquitinase USP5. Physiologically, a blocking peptide and small molecules interfering with the CaV3.2-USP5 protein interaction has been developed to treat neuroinflammation and neuropathic pain in mouse models. Moreover, two genetically encoded calcium channel blockers by using catalytic HECT domain of the E3 ubiquitin ligase Nedd4-2 and nanobodies to β subunit and Nedd4-2 have been shown to have exceptional potency to remove high voltage-gated calcium channels from the plasma membrane. These two blockers showed strong efficacy in reducing hyperalgesia response to nerve injury. Therefore, a deeper understanding of VGCC degradation offers new therapeutic strategies for diseases associated with calcium channel dysfunction, including neuroinflammation, Parkinson’s disease, neuropathic pain and cardiovascular diseases.
biosignaling.biomedcentral.com
July 16, 2025 at 10:11 PM
Testing in grayscale is easier than you think. See how to check your color reliance using the free WAVE tool in just a few clicks. www.youtube.com/watch?v=Rfp2...
Test use of color with WAVE
YouTube video by Pope Tech
www.youtube.com
November 18, 2025 at 3:20 PM
One of the 12 videos Youtube recommended was Dreamcatcher. BOCA. Dance Video. I'm good with that.
www.youtube.com/watch?v=rfp2...
Dreamcatcher(드림캐쳐) 'BOCA' Dance Video (MV ver.)
YouTube video by Dreamcatcher official
www.youtube.com
May 18, 2025 at 11:58 PM
Of course, there's BOCA (The Dance Video) from Dreamcatcher. Another one from August of 2020, smack in the middle of the pandemic.

www.youtube.com/watch?v=rfp2...
Dreamcatcher(드림캐쳐) 'BOCA' Dance Video (MV ver.)
YouTube video by Dreamcatcher official
www.youtube.com
January 4, 2025 at 11:51 PM
Slow week. Not much that I like came out this week. It happens.

I'm still way hyped for Dreamcatcher on the 10 of July.

Dreamcatcher. BOCA. Dance Version.
www.youtube.com/watch?v=rfp2...
Dreamcatcher(드림캐쳐) 'BOCA' Dance Video (MV ver.)
Dreamcatcher(드림캐쳐) 'BOCA' Dance Video (MV ver.)▶ Dreamcatcher(드림캐쳐) More Information- Dreamcatcher YouTube : https://www.youtube.com/dreamcatchero...- Dreamc...
www.youtube.com
June 30, 2024 at 11:13 PM