#RatModel
LightNews LightNews
dmmjournal.bsky.social
Sankalpa Chakraborty, Viswanathan Rajagopalan & co used the ZSF1 #RatModel to investigate early and severe age-related heart failure with preserved ejection fraction and showed novel noncoding and coding markers in early- and/or late-ageing-related hypothyroid #HFpEF.

Read doi.org/10.1242/dmm....
January 8, 2026 at 8:00 AM
statsandresearch.bsky.social
Discover in-depth insights on the 🐀 Rat Model Market, key trends, growth drivers, top players, and future forecasts. Perfect for researchers & investors seeking strategic data. 📊🔬 #RatModel #MarketResearch #PharmaTrends #Biomedical #PreclinicalStudies
Global Rat Model Market Professional Survey Report 2021
Global Rat Model Market, Share, Revenue, Size, Global, Research Report, Rate, Price, Industry Trends, Analysis, Outlook ,Forecast,
www.statsandresearch.com
July 1, 2025 at 11:30 AM
statsandresearch.bsky.social
🔬 𝗘𝘅𝗽𝗹𝗼𝗿𝗲 𝘁𝗵𝗲 𝗹𝗮𝘁𝗲𝘀𝘁 𝗶𝗻𝘀𝗶𝗴𝗵𝘁𝘀 𝗶𝗻 𝘁𝗵𝗲 🐀 𝗥𝗮𝘁 𝗠𝗼𝗱𝗲𝗹 𝗠𝗮𝗿𝗸𝗲𝘁 — 𝘁𝗿𝗲𝗻𝗱𝘀, 𝗸𝗲𝘆 𝗽𝗹𝗮𝘆𝗲𝗿𝘀, 𝗴𝗿𝗼𝘄𝘁𝗵 𝗳𝗼𝗿𝗲𝗰𝗮𝘀𝘁𝘀 & 𝗲𝗺𝗲𝗿𝗴𝗶𝗻𝗴 𝘁𝗲𝗰𝗵𝗻𝗼𝗹𝗼𝗴𝗶𝗲𝘀. 𝗩𝗶𝘁𝗮𝗹 𝗳𝗼𝗿 𝗱𝗿𝘂𝗴 𝗱𝗶𝘀𝗰𝗼𝘃𝗲𝗿𝘆 & 𝗯𝗶𝗼𝗺𝗲𝗱𝗶𝗰𝗮𝗹 𝗥&𝗗. 𝗚𝗮𝗶𝗻 𝘀𝘁𝗿𝗮𝘁𝗲𝗴𝗶𝗰 𝗮𝗱𝘃𝗮𝗻𝘁𝗮𝗴𝗲 𝘄𝗶𝘁𝗵 𝗶𝗻-𝗱𝗲𝗽𝘁𝗵 𝗮𝗻𝗮𝗹𝘆𝘀𝗶𝘀

#RatModel #AnimalModels #BiomedicalResearch #PharmaceuticalResearch #Biotech
Global Rat Model Market Professional Survey Report 2021
Global Rat Model Market, Share, Revenue, Size, Global, Research Report, Rate, Price, Industry Trends, Analysis, Outlook ,Forecast,
www.statsandresearch.com
May 1, 2025 at 8:00 AM
dmmjournal.bsky.social
Jing-Fu Bao, Youhua Liu, Aiqing Li & co developed two methods to simulate human uremic #cardiomyopathy, compared these approaches across several #RatModel and#MouseModel, and identified CCR-2 as a potential therapeutic target.

Read doi.org/10.1242/dmm....
The figure shows global changes of the left ventricle in modified nephrectomy- and adenine-induced uremic cardiomyopathy. Panel A: volcano plot of upregulated and downregulated differentially expressed genes. Panels B and C: gene ontology circle graphs showing the main changes in biological processes, cellular components and molecular functions in uremic cardiomyopathy developed by both approaches. Panel D: gene set enrichment analysis, which identified the primary differences between these two approaches.
February 11, 2026 at 12:01 PM
dmmjournal.bsky.social
Tao Wang, Cynthia Daoud, Abbass Jaber, Isabelle Richard & co generated a new #RatModel of #DuchenneMuscularDystrophy with an exon 45 deletion using CRISPR/Cas9, recapitulating the most-frequent single-exon deletion and key features of #DMD.

Read: doi.org/10.1242/dmm....
Figure showing progressive cardiac abnormalities in DmdΔ45 rats compared with wild‑type controls. Panel A presents a bar graph of heart weight normalized to body weight, with DmdΔ45 rats showing increased values. Panel B displays heart tissue sections: HPS staining on the left reveals structural disorganization, and Sirius Red staining on the right highlights increased fibrosis in DmdΔ45 hearts, particularly in the left and right ventricles. Panel C shows a line graph of cardiac output measured by transthoracic echocardiography from 3 to 18 months, with DmdΔ45 rats exhibiting a decline over time. Panel D presents left ventricular end‑systolic diameter measurements, which are enlarged in DmdΔ45 rats. Panel E shows a bar plot of ejection fraction, reduced in DmdΔ45 animals.
February 20, 2026 at 8:01 AM
miekeroth.com
working on the atlas. #ratmodel #bitbybit
December 7, 2024 at 4:19 AM