Amazing story in @nature.com by @priyaramakrishna.bsky.social @nikogeldner.bsky.social Anders Meibom and others; revealing intracellular Na+ and other elements in roots and ... a new SOS1 location. Moving the field forward!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Elemental cryo-imaging reveals SOS1-dependent vacuolar sodium accumulation - Nature
This study demonstrates that cryo nanoscale secondary ion mass spectrometry (CryoNanoSIMS) enables direct multi-elemental imaging at subcellular resolution of macro- and micronutrients or trace elemen...
www.nature.com
January 16, 2025 at 8:11 AM
Amazing story in @nature.com by @priyaramakrishna.bsky.social @nikogeldner.bsky.social Anders Meibom and others; revealing intracellular Na+ and other elements in roots and ... a new SOS1 location. Moving the field forward!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Elemental cryo-imaging reveals #SOS1-dependent vacuolar #sodium accumulation
www.nature.com/articles/s41...
#PlantScience @nature.com @ivedesmet1978.bsky.social
@priyaramakrishna.bsky.social @plantresearch.bsky.social @plant-sci.bsky.social @plantbiology.bsky.social @plantpowered1971.bsky.social
www.nature.com/articles/s41...
#PlantScience @nature.com @ivedesmet1978.bsky.social
@priyaramakrishna.bsky.social @plantresearch.bsky.social @plant-sci.bsky.social @plantbiology.bsky.social @plantpowered1971.bsky.social
July 13, 2026 at 11:46 AM
Elemental cryo-imaging reveals #SOS1-dependent vacuolar #sodium accumulation
www.nature.com/articles/s41...
#PlantScience @nature.com @ivedesmet1978.bsky.social
@priyaramakrishna.bsky.social @plantresearch.bsky.social @plant-sci.bsky.social @plantbiology.bsky.social @plantpowered1971.bsky.social
www.nature.com/articles/s41...
#PlantScience @nature.com @ivedesmet1978.bsky.social
@priyaramakrishna.bsky.social @plantresearch.bsky.social @plant-sci.bsky.social @plantbiology.bsky.social @plantpowered1971.bsky.social
Very proud and happy to have contributed to this amazing story led by @priyaramakrishna.bsky.social www.nature.com/articles/s41... @nature.com 🧪
Elemental cryo-imaging reveals SOS1-dependent vacuolar sodium accumulation - Nature
This study demonstrates that cryo nanoscale secondary ion mass spectrometry (CryoNanoSIMS) enables direct multi-elemental imaging at subcellular resolution of macro- and micronutrients or trace elemen...
www.nature.com
January 16, 2025 at 7:58 PM
Very proud and happy to have contributed to this amazing story led by @priyaramakrishna.bsky.social www.nature.com/articles/s41... @nature.com 🧪
This is a truly awesome story by @priyaramakrishna.bsky.social & @nikogeldner.bsky.social et al. #CryoSEM imaging of elements!!! They just opened the floodgates for many many cool discoveries!!! www.nature.com/articles/s41...
Elemental cryo-imaging reveals SOS1-dependent vacuolar sodium accumulation - Nature
This study demonstrates that cryo nanoscale secondary ion mass spectrometry (CryoNanoSIMS) enables direct multi-elemental imaging at subcellular resolution of macro- and micronutrients or trace elemen...
www.nature.com
January 15, 2025 at 8:47 PM
This is a truly awesome story by @priyaramakrishna.bsky.social & @nikogeldner.bsky.social et al. #CryoSEM imaging of elements!!! They just opened the floodgates for many many cool discoveries!!! www.nature.com/articles/s41...
Nature research paper: Elemental cryo-imaging reveals SOS1-dependent vacuolar sodium accumulation
https://go.nature.com/3PDa9lG
https://go.nature.com/3PDa9lG
Elemental cryo-imaging reveals SOS1-dependent vacuolar sodium accumulation - Nature
This study demonstrates that cryo nanoscale secondary ion mass spectrometry (CryoNanoSIMS) enables direct multi-elemental imaging at subcellular resolution of macro- and micronutrients or trace elements in plants and may provide insights into the in vivo roles of many transporters.
go.nature.com
January 15, 2025 at 8:14 PM
Nature research paper: Elemental cryo-imaging reveals SOS1-dependent vacuolar sodium accumulation
https://go.nature.com/3PDa9lG
https://go.nature.com/3PDa9lG
Most plants can`t handle salt, but have evolved strategies to survive in it. How do they do it?🌱🧪
Excited to share some of our first insights using a new cryoelemental imaging technique to answer these questions at the subcellular scale!(1/8)
www.nature.com/articles/s41... @nature.com #PlantScience
Excited to share some of our first insights using a new cryoelemental imaging technique to answer these questions at the subcellular scale!(1/8)
www.nature.com/articles/s41... @nature.com #PlantScience
Elemental cryo-imaging reveals SOS1-dependent vacuolar sodium accumulation - Nature
This study demonstrates that cryo nanoscale secondary ion mass spectrometry (CryoNanoSIMS) enables direct multi-elemental imaging at subcellular resolution of macro- and micronutrients or trace elemen...
www.nature.com
January 16, 2025 at 2:51 PM
Most plants can`t handle salt, but have evolved strategies to survive in it. How do they do it?🌱🧪
Excited to share some of our first insights using a new cryoelemental imaging technique to answer these questions at the subcellular scale!(1/8)
www.nature.com/articles/s41... @nature.com #PlantScience
Excited to share some of our first insights using a new cryoelemental imaging technique to answer these questions at the subcellular scale!(1/8)
www.nature.com/articles/s41... @nature.com #PlantScience
Last month paper @Nature: "Elemental cryo-imaging reveals SOS1-dependent vacuolar sodium accumulation" rdcu.be/eaPvi, highlighted by a N&V "Imaging reveals how plants cope with salt" www.nature.com/articles/d41...
These three SIMS direct images of Na+ are just jaw-dropping.
These three SIMS direct images of Na+ are just jaw-dropping.
February 22, 2025 at 1:35 AM
Last month paper @Nature: "Elemental cryo-imaging reveals SOS1-dependent vacuolar sodium accumulation" rdcu.be/eaPvi, highlighted by a N&V "Imaging reveals how plants cope with salt" www.nature.com/articles/d41...
These three SIMS direct images of Na+ are just jaw-dropping.
These three SIMS direct images of Na+ are just jaw-dropping.
A new imaging technique reveals the multiple facet of salt accumulation pattern in plants and the actual role of SOS1 in salt adaptation: to sequester sodium into vacuoles of meristematic cells www.nature.com/articles/s41...
Elemental cryo-imaging reveals SOS1-dependent vacuolar sodium accumulation - Nature
This study demonstrates that cryo nanoscale secondary ion mass spectrometry (CryoNanoSIMS) enables direct multi-elemental imaging at subcellular resolution of macro- and micronutrients or trace elemen...
www.nature.com
January 18, 2025 at 4:44 PM
A new imaging technique reveals the multiple facet of salt accumulation pattern in plants and the actual role of SOS1 in salt adaptation: to sequester sodium into vacuoles of meristematic cells www.nature.com/articles/s41...
www.nature.com/articles/s41...
- Glad we finally start to see, how sodium gets into the vacuole, congrats to all involved!
- Glad we finally start to see, how sodium gets into the vacuole, congrats to all involved!
Elemental cryo-imaging reveals SOS1-dependent vacuolar sodium accumulation - Nature
This study demonstrates that cryo nanoscale secondary ion mass spectrometry (CryoNanoSIMS) enables direct multi-elemental imaging at subcellular resolution of macro- and micronutrients or trace elemen...
www.nature.com
January 24, 2025 at 3:43 PM
www.nature.com/articles/s41...
- Glad we finally start to see, how sodium gets into the vacuole, congrats to all involved!
- Glad we finally start to see, how sodium gets into the vacuole, congrats to all involved!
🌱🧬Cryo nanoscale SIMS reveals sodium distribution in root meristems. At low salt, sodium accumulates in cell walls. At stressful levels, it shifts to vacuoles
SOS1 functions in vacuolar sodium sequestration, not extrusion #plantscience @priyaramakrishna.bsky.social www.nature.com/articles/s41...
SOS1 functions in vacuolar sodium sequestration, not extrusion #plantscience @priyaramakrishna.bsky.social www.nature.com/articles/s41...
Elemental cryo-imaging reveals SOS1-dependent vacuolar sodium accumulation - Nature
This study demonstrates that cryo nanoscale secondary ion mass spectrometry (CryoNanoSIMS) enables direct multi-elemental imaging at subcellular resolution of macro- and micronutrients or trace elemen...
www.nature.com
July 16, 2026 at 8:39 AM
🌱🧬Cryo nanoscale SIMS reveals sodium distribution in root meristems. At low salt, sodium accumulates in cell walls. At stressful levels, it shifts to vacuoles
SOS1 functions in vacuolar sodium sequestration, not extrusion #plantscience @priyaramakrishna.bsky.social www.nature.com/articles/s41...
SOS1 functions in vacuolar sodium sequestration, not extrusion #plantscience @priyaramakrishna.bsky.social www.nature.com/articles/s41...
🌱🧬 Cryo nanoscale SIMS shows sodium shifts from cell walls at low salt to vacuoles at high salt in root meristems.
SOS1 acts in vacuolar sequestration, not extrusion. #plantscience @ivedesmet1978.bsky.social @priyaramakrishna.bsky.social @nature.com www.nature.com/articles/s41...
SOS1 acts in vacuolar sequestration, not extrusion. #plantscience @ivedesmet1978.bsky.social @priyaramakrishna.bsky.social @nature.com www.nature.com/articles/s41...
Elemental cryo-imaging reveals SOS1-dependent vacuolar sodium accumulation - Nature
This study demonstrates that cryo nanoscale secondary ion mass spectrometry (CryoNanoSIMS) enables direct multi-elemental imaging at subcellular resolution of macro- and micronutrients or trace elemen...
www.nature.com
July 9, 2026 at 10:11 AM
🌱🧬 Cryo nanoscale SIMS shows sodium shifts from cell walls at low salt to vacuoles at high salt in root meristems.
SOS1 acts in vacuolar sequestration, not extrusion. #plantscience @ivedesmet1978.bsky.social @priyaramakrishna.bsky.social @nature.com www.nature.com/articles/s41...
SOS1 acts in vacuolar sequestration, not extrusion. #plantscience @ivedesmet1978.bsky.social @priyaramakrishna.bsky.social @nature.com www.nature.com/articles/s41...
New study from the lab! Colleagues found that roots do not expel salt through SOS1 during salt stress, but rather store it inside the vacuole.
Learn more about how they solved this by developing a new technology: CRYO-Nano-SIM
www.nature.com/articles/s41...
Learn more about how they solved this by developing a new technology: CRYO-Nano-SIM
www.nature.com/articles/s41...
Elemental cryo-imaging reveals SOS1-dependent vacuolar sodium accumulation - Nature
This study demonstrates that cryo nanoscale secondary ion mass spectrometry (CryoNanoSIMS) enables direct multi-elemental imaging at subcellular resolution of macro- and micronutrients or trace elemen...
www.nature.com
January 16, 2025 at 10:28 AM
New study from the lab! Colleagues found that roots do not expel salt through SOS1 during salt stress, but rather store it inside the vacuole.
Learn more about how they solved this by developing a new technology: CRYO-Nano-SIM
www.nature.com/articles/s41...
Learn more about how they solved this by developing a new technology: CRYO-Nano-SIM
www.nature.com/articles/s41...
Increased soil salinity causes crop losses, due to cellular Na+ toxicity. @nature scientists use CryoNanoSIMS for high-res imaging of the subcellular distribution of Na+ and K+ in root cells of Arabidopsis and rice, gaining insights into consequences of salt stress. www.nature.com/articles/s41...
Elemental cryo-imaging reveals SOS1-dependent vacuolar sodium accumulation - Nature
This study demonstrates that cryo nanoscale secondary ion mass spectrometry (CryoNanoSIMS) enables direct multi-elemental imaging at subcellular resolution of macro- and micronutrients or trace elemen...
www.nature.com
January 15, 2025 at 10:21 PM
Increased soil salinity causes crop losses, due to cellular Na+ toxicity. @nature scientists use CryoNanoSIMS for high-res imaging of the subcellular distribution of Na+ and K+ in root cells of Arabidopsis and rice, gaining insights into consequences of salt stress. www.nature.com/articles/s41...
Elemental cryo-imaging reveals SOS1-dependent vacuolar sodium accumulation
Elemental cryo-imaging reveals SOS1-dependent vacuolar sodium accumulation - Nature
This study demonstrates that cryo nanoscale secondary ion mass spectrometry (CryoNanoSIMS) enables direct multi-elemental imaging at subcellular resolution of macro- and micronutrients or trace elemen...
doi.org
January 18, 2025 at 6:46 PM
Elemental cryo-imaging reveals SOS1-dependent vacuolar sodium accumulation
Un très bel article de @priyaramakrishna.bsky.social et al., paru en janvier dans @nature.com, explore les mécanismes cellulaires et moléculaires de cette détoxification à une résolution inédite en exploitant le potentiel du CryoNanoSIMS.
doi.org/10.1038/s415...
doi.org/10.1038/s415...
Elemental cryo-imaging reveals SOS1-dependent vacuolar sodium accumulation - Nature
This study demonstrates that cryo nanoscale secondary ion mass spectrometry (CryoNanoSIMS) enables direct multi-elemental imaging at subcellular resolution of macro- and micronutrients or trace elemen...
doi.org
March 12, 2025 at 11:50 AM
Un très bel article de @priyaramakrishna.bsky.social et al., paru en janvier dans @nature.com, explore les mécanismes cellulaires et moléculaires de cette détoxification à une résolution inédite en exploitant le potentiel du CryoNanoSIMS.
doi.org/10.1038/s415...
doi.org/10.1038/s415...
RRID:Addgene_12217, was just reported to be used in "Sos1 ablation alters focal adhesion dynamics and increases Mmp2/9-dependent gelatinase activity in primary mouse embryonic fibroblasts". Thank you for making your methods matter! #STMpublishing #methodsmatter
doi.org
April 2, 2025 at 7:00 AM
RRID:Addgene_12217, was just reported to be used in "Sos1 ablation alters focal adhesion dynamics and increases Mmp2/9-dependent gelatinase activity in primary mouse embryonic fibroblasts". Thank you for making your methods matter! #STMpublishing #methodsmatter
‘Newly developed cryo nanoscale secondary ion mass spectrometry ion microprobe, which allows high-resolution elemental imaging of cryo-preserved samples and reveals the subcellular distributions of key macronutrients and micronutrients’
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Elemental cryo-imaging reveals SOS1-dependent vacuolar sodium accumulation - Nature
This study demonstrates that cryo nanoscale secondary ion mass spectrometry (CryoNanoSIMS) enables direct multi-elemental imaging at subcellular resolution of macro- and micronutrients or trace elemen...
www.nature.com
January 16, 2025 at 7:17 AM
‘Newly developed cryo nanoscale secondary ion mass spectrometry ion microprobe, which allows high-resolution elemental imaging of cryo-preserved samples and reveals the subcellular distributions of key macronutrients and micronutrients’
www.nature.com/articles/s41...
www.nature.com/articles/s41...
🧩Mechanistically, PI3K activity promotes PIP3-dependent membrane recruitment of GAB1 to form an EGFR/SHP2/SOS1 signalosome, enabling wild-type RAS/MAPK signaling. What’s more? This leads to resistance to KRAS inhibition, providing a rationale for co-targeting PI3KI and KRAS. 🎯
May 7, 2026 at 4:23 PM
🧩Mechanistically, PI3K activity promotes PIP3-dependent membrane recruitment of GAB1 to form an EGFR/SHP2/SOS1 signalosome, enabling wild-type RAS/MAPK signaling. What’s more? This leads to resistance to KRAS inhibition, providing a rationale for co-targeting PI3KI and KRAS. 🎯
For information on the technology, please check out:
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Elemental cryo-imaging reveals SOS1-dependent vacuolar sodium accumulation - Nature
This study demonstrates that cryo nanoscale secondary ion mass spectrometry (CryoNanoSIMS) enables direct multi-elemental imaging at subcellular resolution of macro- and micronutrients or trace elemen...
www.nature.com
May 29, 2025 at 11:47 PM
For information on the technology, please check out:
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Very happy to contribute to Fernando C. Baltana's latest work uncovering a new role for Sos1 in focal adhesion dinamycs rdcu.be/eciCZ
Sos1 ablation alters focal adhesion dynamics and increases Mmp2/9-dependent gelatinase activity in primary mouse embryonic fibroblasts
rdcu.be
March 5, 2025 at 4:08 PM
Very happy to contribute to Fernando C. Baltana's latest work uncovering a new role for Sos1 in focal adhesion dinamycs rdcu.be/eciCZ