O adm está assim
September 10, 2025 at 8:29 PM
O adm está assim
6/24 Immunosuppression in IgAN?
STOP IGA—No benefit in GFR decline in white population done in Europe, even in the 10-year follow-up study
TESTING and low-dose testing have shown improvement in clinical endpoints in a Chinese IgAN population
STOP IGA—No benefit in GFR decline in white population done in Europe, even in the 10-year follow-up study
TESTING and low-dose testing have shown improvement in clinical endpoints in a Chinese IgAN population
June 3, 2026 at 1:38 PM
6/24 Immunosuppression in IgAN?
STOP IGA—No benefit in GFR decline in white population done in Europe, even in the 10-year follow-up study
TESTING and low-dose testing have shown improvement in clinical endpoints in a Chinese IgAN population
STOP IGA—No benefit in GFR decline in white population done in Europe, even in the 10-year follow-up study
TESTING and low-dose testing have shown improvement in clinical endpoints in a Chinese IgAN population
And just in time NDT publishes a small trial showing dramatic antiproteinuric and GFR stabilizing effect of calcitriol in IgAN! Calcitriol is the new Flozin. Stop the Press
/s
academic.oup.com/ndt/advance-...
/s
academic.oup.com/ndt/advance-...
September 19, 2025 at 12:39 PM
And just in time NDT publishes a small trial showing dramatic antiproteinuric and GFR stabilizing effect of calcitriol in IgAN! Calcitriol is the new Flozin. Stop the Press
/s
academic.oup.com/ndt/advance-...
/s
academic.oup.com/ndt/advance-...
Dr. Heather reich speaks on IgA nephropathy. Comparing #TESTING vs #STOP-IgAN trial vs. #DAPA-CKD with Race, #Proteinuria, rapid decline in #GFR (annual GFR loss). An excellent review and comparision! #theISN
March 28, 2025 at 3:12 AM
Dr. Heather reich speaks on IgA nephropathy. Comparing #TESTING vs #STOP-IgAN trial vs. #DAPA-CKD with Race, #Proteinuria, rapid decline in #GFR (annual GFR loss). An excellent review and comparision! #theISN
''Today there are emerging precision therapies that can preserve kidney function and potentially stop IgAN in its tracks. But early diagnosis is crucial. The sooner treatment gets underway, the better the odds that “we can push off the need for dialysis, hopefully permanently,”says Brad Rovin[...]''
A silent immune attack on the kidney could be treated by new drugs, if it can be found early
IgA nephropathy, an immune assault on the kidneys, is often missed. New treatments mean that spotting it sooner might save lives
www.scientificamerican.com
March 22, 2026 at 2:00 AM
''Today there are emerging precision therapies that can preserve kidney function and potentially stop IgAN in its tracks. But early diagnosis is crucial. The sooner treatment gets underway, the better the odds that “we can push off the need for dialysis, hopefully permanently,”says Brad Rovin[...]''
1/2 I do agree with the fact that the field is moving fast and that IgAN trials have turned problematic. We had to stop screening pts for a ravulizumab trial because can’t offer placebo to pts when we have iptacopan and sibeprenlimab available. And SOC in CKD trials has been evolving too. But….
June 3, 2026 at 12:57 AM
1/2 I do agree with the fact that the field is moving fast and that IgAN trials have turned problematic. We had to stop screening pts for a ravulizumab trial because can’t offer placebo to pts when we have iptacopan and sibeprenlimab available. And SOC in CKD trials has been evolving too. But….
History of steroids in IgAN
STOP-IGA
TESTING
TESTING 2.0
Interesting to see long term proteinuria and GFR data…not impressive (but I doubt we will see any 7 year data from other treatments)
#RKDSummit
STOP-IGA
TESTING
TESTING 2.0
Interesting to see long term proteinuria and GFR data…not impressive (but I doubt we will see any 7 year data from other treatments)
#RKDSummit
November 23, 2024 at 5:01 PM
History of steroids in IgAN
STOP-IGA
TESTING
TESTING 2.0
Interesting to see long term proteinuria and GFR data…not impressive (but I doubt we will see any 7 year data from other treatments)
#RKDSummit
STOP-IGA
TESTING
TESTING 2.0
Interesting to see long term proteinuria and GFR data…not impressive (but I doubt we will see any 7 year data from other treatments)
#RKDSummit
Dr. Heather reich speaks on IgA nephropathy. Comparing #TESTING vs #STOP-IgAN trial vs. #DAPA-CKD with Race, #Proteinuria, rapid decline in #GFR (annual GFR loss). An excellent review and comparision! #theISN
March 28, 2025 at 3:39 AM
Dr. Heather reich speaks on IgA nephropathy. Comparing #TESTING vs #STOP-IgAN trial vs. #DAPA-CKD with Race, #Proteinuria, rapid decline in #GFR (annual GFR loss). An excellent review and comparision! #theISN