#WEHI researchers developed #Partita, a high-density mouse genome-wide #CRISPRa library (263,460 sgRNAs), mapping #cancer dependencies, Irx5-driven venetoclax resistance, and in vivo MYC-synergistic oncogenes (Runx2/Runx3/Csf1r). 🐭🤖 #ScienceAdvances2026 #DrugResistance #InVivoScreening