📍 Molecular mechanism identified for the treatment of #SkinFibrosis in #SystemicSclerosis:
A team from #MedUniVienna found that inhibiting the metabolic enzyme NNMT reduces pathological fibroblast activation and skin fibrosis in preclinical models.
Read more! ⬇️
📰 @ard.eular.org
A team from #MedUniVienna found that inhibiting the metabolic enzyme NNMT reduces pathological fibroblast activation and skin fibrosis in preclinical models.
Read more! ⬇️
📰 @ard.eular.org
New therapeutic target for skin fibrosis in systemic sclerosis identified
Study details!
www.meduniwien.ac.at
November 6, 2026 at 8:48 AM
📍 Molecular mechanism identified for the treatment of #SkinFibrosis in #SystemicSclerosis:
A team from #MedUniVienna found that inhibiting the metabolic enzyme NNMT reduces pathological fibroblast activation and skin fibrosis in preclinical models.
Read more! ⬇️
📰 @ard.eular.org
A team from #MedUniVienna found that inhibiting the metabolic enzyme NNMT reduces pathological fibroblast activation and skin fibrosis in preclinical models.
Read more! ⬇️
📰 @ard.eular.org
Researchers identify #DKK3 as a driver of radiation-induced #SkinFibrosis, where keratinocyte DKK3 promotes ROS, TGF-β/Wnt signaling, and M2 #MacrophagePolarization; DKK3 deficiency reduces dermal hyperplasia and fibrosis. @dkfz.bsky.social @umich.edu
#STTT: doi.org/10.1038/s413...
#STTT: doi.org/10.1038/s413...
March 4, 2026 at 4:25 PM
Researchers identify #DKK3 as a driver of radiation-induced #SkinFibrosis, where keratinocyte DKK3 promotes ROS, TGF-β/Wnt signaling, and M2 #MacrophagePolarization; DKK3 deficiency reduces dermal hyperplasia and fibrosis. @dkfz.bsky.social @umich.edu
#STTT: doi.org/10.1038/s413...
#STTT: doi.org/10.1038/s413...