#Snoutscope
@patrickzager.bsky.social acquired this lovely 3D timelapse of live neutrophil membrane protrusions on the snoutscope at the UCSF Center for Advanced Light Microscopy. Shown are three orthogonal maximum intensity projections.
March 10, 2026 at 11:26 PM
Production has started for a new #Snoutscope objective, AMS-AGY v3. It has significantly larger FOV and some other tweaks from v1 and v2. Currently accepting pre-orders. The price will need to increase modestly after deliveries start late October.
July 9, 2025 at 8:00 PM
Another #snoutscope imaging session at the UCSF Center for Advanced Light Microscopy! This time, with neutrophils! Courtesy of Patrick Zager in the Weiner lab.

Neutrophil plasma membranes are labeled to show 3D filopodia and lamellipodia dynamics at 1 volume/second.
June 24, 2025 at 1:31 AM
I got a text from Yovan Bodal, who just used our #snoutscope @UCSF to image fly embryos. His quote says it all!

"This was the best results we've gotten on any instrument, possibly for the least amount of work on my end. Here's a GIF of individual mRNAs coming off the gene as they get transcribed:"
June 21, 2025 at 2:00 PM
I'll kick off my bsky profile with a great 3D fluorescence microscopy time-lapse. My buddies Joe Brzostowski and Rachel Stadler (NIH) acquired this on their #snoutscope that I helped them build.

Shown is a fluorescent actin marker in Dictyostelium. Joe and Rachel called this "The Mark of Zorro!"
February 4, 2025 at 3:26 AM
@kahsage.bsky.social is killing it with these teaching tools for #snoutscope training at the UCSF Center for Advanced Light Microscopy. Fantastic illustrations and a whiteboard in the room. Brilliant!
June 26, 2025 at 6:57 PM
I can attest that Joe Brzostowski and Rachel Stadler just finished their #snoutscope at the Twinbrook Imaging Facility at the NIH! You should definitely add them to the snoutclub! (I don't know if either of them are on bsky yet though)

See example timelapse: bsky.app/profile/tann...
I'll kick off my bsky profile with a great 3D fluorescence microscopy time-lapse. My buddies Joe Brzostowski and Rachel Stadler (NIH) acquired this on their #snoutscope that I helped them build.

Shown is a fluorescent actin marker in Dictyostelium. Joe and Rachel called this "The Mark of Zorro!"
February 4, 2025 at 3:31 AM