#StrainDifferences
🌟NEW PREPRINT ALERT!🌟

We are very pleased to introduce #StrainDifferences: “Genetic background sets the trajectory of cancer evolution”

www.biorxiv.org/content/10.1...

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Genetic background sets the trajectory of cancer evolution
Human cancers are heterogeneous. Their genomes evolve from genetically diverse germlines in complex and dynamic environments, including exposure to potential carcinogens. This heterogeneity of humans,...
www.biorxiv.org
January 15, 2025 at 7:19 PM
🧬NEW PAPER🧬

To what extent is cancer development deterministic? Does the germline genome affect that predictability?

Find out in our #StrainDifferences paper @nature.com

"Genetic background sets the trajectory of experimental cancer evolution"
www.nature.com/articles/s41...

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Genetic background sets the trajectory of experimental cancer evolution - Nature
Experimentally replaying tumour evolution in divergent mouse strains reveals the importance of interactions between genetic ancestry and acquired cancer-driving mutations in shaping the earliest stage...
www.nature.com
July 26, 2026 at 11:01 PM