Establishing a firm scientific basis for predicting what will happen to the climate, and in the shorter term to weather, has been the challenge that has occupied Syukuro Manabe's entire working life. In the interview with Adam Smith, recorded amidst the happy chaos resulting from the early morning announcement of his Nobel Prize in Physics, Manabe reflects on the importance of fundamental research. As he says, "The prediction of climate change without accompanying understanding of it is no better than the prediction of a fortune teller."