At ELRIG 2026?

Visit us at stand D06 for a chat and discover the TarSeer™ BRETSA™ Target Engagement System in Dr Craig Malcolm's Cell Engineering Track talk, on Wednesday 14 October at 4.15 p.m.

#ELRIG2026 #TargetEngagement #DrugDiscovery

Thanks to Margherita Brindisi for hosting me in Naples today. www.linkedin.com/posts/marghe...

Biochemical and cellular binding assays don't always align

NanoBRET® Target Engagement Assays measure compound binding to full-length proteins in live cells for a more physiologically relevant view of selectivity and& potency

More at: https://ow.ly/OBgc50Z385J

#TargetEngagement #DrugDiscovery

TarSeer™ BRETSA™ measures target engagement for difficult proteins in live cells via thermal stability. Addresses weak binders & targets lacking probes.

Practical drug discovery tool. SLAS 2026.

https://ow.ly/Rj2G50YcPTt

#DrugDiscovery #TargetEngagement

Tivantinib entered trials as a MET inhibitor, then turned out to act through another mechanism.

This blog explores why confirming cellular target engagement is essential in drug discovery

👉https://tinyurl.com/TivantinibBlog

#DrugDiscovery #TargetEngagement

Thanks my #coinvestigators for opportunity to present data of #D3S_001, a novel #KRASG12C inhibitor in #G12Ci pre-treated #NSCLC at @theaacr.bsky.social #AACR25. Strong & rapid #targetengagement confer superior #efficacy c.f. 1st generation G12Ci.

✔️ORR 30%; DCR 80% in KRASG12Ci pre-treated popn.